Development Level

Tbio 166 | 11,445
Tchem 24 | 1,598
Tdark 15 | 6,588
Tclin 8 | 613

Collection

Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

abnormal behavior 6 | 298
preweaning lethality, complete... 6 | 979
preweaning lethality, incomple... 5 | 499
abnormal bone structure 4 | 187
abnormal sleep behavior 4 | 70
cataract 4 | 92
decreased lean body mass 4 | 135
increased mean corpuscular hem... 4 | 36
abnormal humerus morphology 3 | 11
abnormal lens morphology 3 | 81
decreased circulating glucose ... 3 | 126
decreased total body fat amoun... 3 | 207
enlarged heart 3 | 210
hypoactivity 3 | 132
increased or absent threshold ... 3 | 101
abnormal behavioral response t... 2 | 66
abnormal bone mineralization 2 | 38
abnormal coat-hair pigmentatio... 2 | 64
abnormal femur morphology 2 | 14
abnormal seminal vesicle morph... 2 | 114
decreased body weight 2 | 161
decreased bone mineral density 2 | 126
decreased circulating creatini... 2 | 39
decreased circulating potassiu... 2 | 20
decreased circulating triglyce... 2 | 79
decreased heart weight 2 | 27
embryonic lethality prior to t... 2 | 278
hyperactivity 2 | 148
increased body weight 2 | 25
increased bone mineral content 2 | 108
increased bone mineral density 2 | 72
increased circulating alkaline... 2 | 122
increased circulating chloride... 2 | 41
increased circulating sodium l... 2 | 71
increased circulating triglyce... 2 | 42
increased fasted circulating g... 2 | 76
increased heart weight 2 | 62
increased lean body mass 2 | 172
increased mean corpuscular hem... 2 | 96
increased startle reflex 2 | 112
abnormal coat appearance 1 | 31
abnormal epididymis morphology 1 | 42
abnormal eye morphology 1 | 68
abnormal gait 1 | 69
abnormal heart morphology 1 | 162
abnormal incisor color 1 | 3
abnormal joint morphology 1 | 23
abnormal lung morphology 1 | 26
abnormal optic disc morphology 1 | 10
abnormal skin morphology 1 | 50
abnormal spleen morphology 1 | 55
abnormal tail morphology 1 | 25
abnormal tail movements 1 | 12
abnormal testis morphology 1 | 43
abnormal tibia morphology 1 | 14
abnormal tooth morphology 1 | 24
brachydactyly 1 | 19
convulsive seizures 1 | 13
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased circulating insulin ... 1 | 76
decreased circulating phosphat... 1 | 27
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased mature B cell number 1 | 7
decreased mean corpuscular hem... 1 | 31
decreased neutrophil cell numb... 1 | 42
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
decreased thermal nociceptive ... 1 | 2
decreased vertical activity 1 | 208
dilated heart left ventricle 1 | 11
embryonic lethality prior to o... 1 | 239
enlarged epididymis 1 | 31
enlarged heart atrium 1 | 4
enlarged seminal vesicle 1 | 10
enlarged spleen 1 | 41
enlarged uterus 1 | 11
eye hemorrhage 1 | 1
hydrometra 1 | 53
impaired glucose tolerance 1 | 75
impaired righting response 1 | 26
improved glucose tolerance 1 | 79
increased aggression 1 | 4
increased blood urea nitrogen ... 1 | 48
increased blood uric acid leve... 1 | 5
increased body length 1 | 32
increased circulating HDL chol... 1 | 80
increased circulating thyroxin... 1 | 7
increased hematocrit 1 | 46
increased leukocyte cell numbe... 1 | 47
kinked tail 1 | 2
limb grasping 1 | 41
mammalian phenotype 1 | 17
prenatal lethality prior to he... 1 | 87
short tibia 1 | 97
small seminal vesicle 1 | 10
small superior vagus ganglion 1 | 74
small testis 1 | 58
syndactyly 1 | 23

Disease

limb girdle muscular dystrophy 2A 213 | 213
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Digestive Tract 213 | 17,369
Endocrine System 213 | 18,159
Male tissues 213 | 17,142
Skin and soft tissues 213 | 17,230
Nervous System 212 | 16,725
Blood and immune system 211 | 16,909
Female tissues 211 | 17,400
Cardiovascular System 210 | 15,192
Liver and Pancreas 210 | 16,750
Urinary Tract 210 | 16,678
Respiratory system 208 | 16,393

Target Family

Non-IDG 159 | 12,091
Enzyme 41 | 4,145
Kinase 5 | 634
Transporter 4 | 473
Ion Channel 2 | 344
GPCR 1 | 408
Transcription Factor 1 | 1,400

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
LHFPL tetraspan subfamily member 6 protein LHFPL6 Tdark Non-IDG -0.47054 2.66 66
Epithelial membrane protein 1 EMP1 Tbio Non-IDG -2.60119 387.7 88
Tubulin beta-6 chain TUBB6 Tclin Non-IDG -0.94163 8.01 85
Transmembrane glycoprotein NMB GPNMB Tbio Non-IDG -2.05817 130.8 293
Scavenger receptor cysteine-rich type 1 protein M130 CD163 Tbio Non-IDG -2.93036 825.2 985
Paraneoplastic antigen-like protein 8A PNMA8A Tdark Non-IDG 0.56 0.25 30
Protein S100-A11 S100A11 Tbio Non-IDG -2.01412 110.0 311
60S ribosomal protein L3 RPL3 Tbio Non-IDG -2.02901 103.9 190
Mitochondrial uncoupling protein 3 UCP3 Tbio Non-IDG -2.74050 585.4 181
EKC/KEOPS complex subunit TPRKB TPRKB Tbio Non-IDG -0.79500 4.88 134