Development Level

Tbio 2,103 | 11,651
Tdark 400 | 6,593
Tchem 320 | 1,388
Tclin 128 | 612

Collection

Kinase: IDG Consortium (Target... 13 | 125
GPCR: IDG Consortium (Targets) 9 | 126
GPCR: IDG Consortium (Complete... 7 | 25
Ion Channel: IDG Consortium (T... 7 | 99
Kinase: IDG Consortium (Comple... 3 | 37

IMPC Phenotype

preweaning lethality, complete... 145 | 979
preweaning lethality, incomple... 102 | 499
abnormal behavior 58 | 298
enlarged heart 48 | 210
decreased total body fat amoun... 47 | 207
embryonic lethality prior to t... 44 | 278
abnormal embryo size 40 | 220
decreased vertical activity 39 | 208
increased lean body mass 37 | 172
abnormal bone structure 36 | 187
abnormal heart morphology 32 | 162
embryonic lethality prior to o... 30 | 239
hypoactivity 30 | 132
increased total body fat amoun... 29 | 134
decreased body weight 28 | 161
increased circulating alkaline... 27 | 122
decreased bone mineral content 26 | 151
increased or absent threshold ... 26 | 101
decreased grip strength 24 | 116
decreased prepulse inhibition 24 | 82
hyperactivity 24 | 148
increased circulating HDL chol... 24 | 80
decreased lean body mass 23 | 135
increased bone mineral content 23 | 108
male infertility 22 | 123
abnormal seminal vesicle morph... 21 | 114
decreased bone mineral density 21 | 126
decreased circulating choleste... 21 | 93
decreased startle reflex 21 | 75
increased circulating choleste... 19 | 66
increased mean corpuscular vol... 19 | 92
abnormal kidney morphology 18 | 65
cataract 18 | 92
decreased circulating glucose ... 18 | 126
decreased lymphocyte cell numb... 18 | 83
increased heart weight 18 | 62
decreased body length 17 | 101
embryonic growth retardation 17 | 106
increased startle reflex 17 | 112
short tibia 17 | 97
abnormal eye morphology 16 | 68
decreased circulating insulin ... 16 | 76
abnormal retina morphology 15 | 71
decreased leukocyte cell numbe... 15 | 73
increased mean corpuscular hem... 15 | 96
abnormal lens morphology 14 | 81
abnormal spleen morphology 14 | 55
decreased fasted circulating g... 14 | 65
impaired glucose tolerance 14 | 75
improved glucose tolerance 14 | 79
increased fasted circulating g... 14 | 76
increased hematocrit 14 | 46
small superior vagus ganglion 14 | 74
abnormal gait 13 | 69
abnormal sleep behavior 13 | 70
decreased circulating HDL chol... 13 | 68
enlarged spleen 13 | 41
increased monocyte cell number 13 | 63
thrombocytopenia 13 | 56
decreased circulating serum al... 12 | 82
decreased circulating triglyce... 12 | 79
increased bone mineral density 12 | 72
increased neutrophil cell numb... 12 | 46
abnormal skin morphology 11 | 50
decreased hemoglobin content 11 | 68
decreased mean corpuscular vol... 11 | 79
female infertility 11 | 60
increased erythrocyte cell num... 11 | 39
abnormal behavioral response t... 10 | 66
abnormal coat-hair pigmentatio... 10 | 64
decreased blood urea nitrogen ... 10 | 51
decreased circulating calcium ... 10 | 36
decreased red blood cell distr... 10 | 41
edema 10 | 59
hydrometra 10 | 53
increased blood urea nitrogen ... 10 | 48
prenatal lethality prior to he... 10 | 87
abnormal neural tube closure 9 | 46
decreased erythrocyte cell num... 9 | 62
enlarged lymph nodes 9 | 37
increased circulating triglyce... 9 | 42
abnormal bone mineralization 8 | 38
abnormal retinal blood vessel ... 8 | 26
abnormal testis morphology 8 | 43
decreased circulating LDL chol... 8 | 38
decreased circulating alanine ... 8 | 47
decreased circulating alkaline... 8 | 46
decreased circulating aspartat... 8 | 34
decreased circulating creatini... 8 | 39
decreased circulating total pr... 8 | 49
decreased mean corpuscular hem... 8 | 50
decreased neutrophil cell numb... 8 | 42
increased circulating sodium l... 8 | 71
increased grip strength 8 | 41
increased hemoglobin content 8 | 45
increased leukocyte cell numbe... 8 | 47
limb grasping 8 | 41
microphthalmia 8 | 26
small testis 8 | 58
cardiovascular system phenotyp... 7 | 36

Disease

invasive ductal carcinoma 2,951 | 2,951
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Female tissues 2,927 | 17,400
Endocrine System 2,926 | 18,159
Digestive Tract 2,922 | 17,369
Skin and soft tissues 2,921 | 17,230
Male tissues 2,917 | 17,142
Blood and immune system 2,912 | 16,909
Liver and Pancreas 2,911 | 16,750
Urinary Tract 2,911 | 16,678
Respiratory system 2,902 | 16,393
Nervous System 2,893 | 16,725
Cardiovascular System 2,829 | 15,192

Target Family

Non-IDG 1,744 | 12,091
Enzyme 664 | 4,145
Transcription Factor 196 | 1,400
Kinase 128 | 634
Transporter 75 | 473
GPCR 59 | 408
Ion Channel 34 | 344
Epigenetic 32 | 242
Nuclear Receptor 14 | 48
TF/Epigenetic 5 | 38

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Calcium uptake protein 3, mitochondrial MICU3 Tdark Non-IDG -0.21085 1.14 50
Paired mesoderm homeobox protein 1 PRRX1 Tbio Transcription Factor -1.58479 38.8 304
Integrin alpha-11 ITGA11 Tbio Non-IDG -1.13736 14.3 76
Eukaryotic translation initiation factor 1 EIF1 Tbio Non-IDG -2.06392 118.5 92
ATP-binding cassette sub-family A member 1 ABCA1 Tclin Transporter -3.15111 1451.8 388
Calcium homeostasis modulator protein 6 CALHM6 Tdark Ion Channel -0.43644 4.12 26
Transcription factor HES-1 HES1 Tbio Transcription Factor -1.77409 55.5 444
UPF0577 protein KIAA1324 KIAA1324 Tbio Non-IDG -1.30268 19.8 137
CMRF35-like molecule 9 CD300LG Tdark Non-IDG -0.92828 10.3 49
Butyrophilin-like protein 9 BTNL9 Tdark Non-IDG -0.69979 4.69 67