Development Level

Tbio 201 | 11,178
Tchem 49 | 1,885
Tdark 27 | 6,569
Tclin 10 | 612

Collection

Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

preweaning lethality, complete... 19 | 979
preweaning lethality, incomple... 11 | 499
abnormal behavior 8 | 298
enlarged heart 6 | 210
abnormal bone structure 5 | 187
abnormal heart morphology 5 | 162
abnormal retina morphology 5 | 71
decreased body weight 5 | 161
decreased total body fat amoun... 5 | 207
embryonic lethality prior to o... 5 | 239
embryonic lethality prior to t... 5 | 278
abnormal lens morphology 4 | 81
decreased circulating choleste... 4 | 93
decreased mean corpuscular vol... 4 | 79
increased lean body mass 4 | 172
increased or absent threshold ... 4 | 101
short tibia 4 | 97
abnormal embryo size 3 | 220
abnormal seminal vesicle morph... 3 | 114
abnormal spleen morphology 3 | 55
abnormal tooth morphology 3 | 24
cataract 3 | 92
decreased circulating iron lev... 3 | 32
decreased grip strength 3 | 116
decreased vertical activity 3 | 208
impaired glucose tolerance 3 | 75
increased mean corpuscular vol... 3 | 92
increased startle reflex 3 | 112
abnormal brain morphology 2 | 13
abnormal cranium morphology 2 | 36
abnormal eye morphology 2 | 68
abnormal incisor morphology 2 | 4
abnormal sleep behavior 2 | 70
abnormal snout morphology 2 | 23
absent startle reflex 2 | 24
anophthalmia 2 | 33
decreased body length 2 | 101
decreased bone mineral content 2 | 151
decreased circulating HDL chol... 2 | 68
decreased circulating aspartat... 2 | 34
decreased circulating bilirubi... 2 | 19
decreased circulating glucose ... 2 | 126
decreased circulating insulin ... 2 | 76
decreased circulating phosphat... 2 | 27
decreased circulating serum al... 2 | 82
decreased circulating total pr... 2 | 49
decreased circulating triglyce... 2 | 79
decreased lean body mass 2 | 135
decreased mean corpuscular hem... 2 | 31
decreased startle reflex 2 | 75
hyperactivity 2 | 148
hypoactivity 2 | 132
increased blood urea nitrogen ... 2 | 48
increased bone mineral density 2 | 72
increased circulating triglyce... 2 | 42
increased fasted circulating g... 2 | 76
increased heart weight 2 | 62
increased leukocyte cell numbe... 2 | 47
increased mean corpuscular hem... 2 | 96
increased mean corpuscular hem... 2 | 36
prenatal lethality prior to he... 2 | 87
vertebral transformation 2 | 12
abnormal heart left ventricle ... 1 | 16
abnormal joint morphology 1 | 23
abnormal locomotor behavior 1 | 24
abnormal neural tube morpholog... 1 | 12
abnormal retinal vasculature m... 1 | 27
abnormal tail movements 1 | 12
abnormal vocalization 1 | 21
convulsive seizures 1 | 13
decreased IgE level 1 | 6
decreased IgG1 level 1 | 8
decreased caudal vertebrae num... 1 | 53
decreased circulating LDL chol... 1 | 38
decreased circulating amylase ... 1 | 28
decreased exploration in new e... 1 | 11
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased mean platelet volume 1 | 25
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
dilated heart left ventricle 1 | 11
edema 1 | 59
embryonic growth retardation 1 | 106
enlarged spleen 1 | 41
hydrometra 1 | 53
increased aggression 1 | 4
increased body length 1 | 32
increased bone mineral content 1 | 108
increased cardiac muscle contr... 1 | 8
increased circulating alkaline... 1 | 122
increased circulating iron lev... 1 | 30
increased circulating serum al... 1 | 22
increased circulating sodium l... 1 | 71
increased exploration in new e... 1 | 8
increased hemoglobin content 1 | 45
microphthalmia 1 | 26
persistence of hyaloid vascula... 1 | 33
polycystic kidney 1 | 15
small superior vagus ganglion 1 | 74

Disease

interstitial lung disease 287 | 287
Carcinoma 11,192 | 11,192
ovarian cancer 8,297 | 8,297
osteosarcoma 7,766 | 7,766
psoriasis 6,514 | 6,514
medulloblastoma, large-cell 6,086 | 6,086
glioblastoma 5,635 | 5,635
atypical teratoid / rhabdoid tumor 4,971 | 4,971
lung cancer 4,607 | 4,607
ependymoma 4,559 | 4,559
group 3 medulloblastoma 4,002 | 4,002
adult high grade glioma 3,701 | 3,701
Breast cancer 3,469 | 3,469
intraductal papillary-mucinous neoplasm (IPMN) 3,204 | 3,204
malignant mesothelioma 3,135 | 3,135
Astrocytoma, Pilocytic 3,006 | 3,006
primitive neuroectodermal tumor 2,957 | 2,957
intraductal papillary-mucinous carcinoma (IPMC) 2,902 | 2,902
intraductal papillary-mucinous adenoma (IPMA) 2,872 | 2,872
invasive ductal carcinoma 2,867 | 2,867
non-small cell lung cancer 2,799 | 2,799
oligodendroglioma 2,768 | 2,768
lung carcinoma 2,755 | 2,755
lung adenocarcinoma 2,627 | 2,627
Kidney cancer 2,548 | 2,548
astrocytic glioma 2,530 | 2,530
Cancer 2,388 | 2,388
pancreatic cancer 2,322 | 2,322
interstitial cystitis 2,237 | 2,237
subependymal giant cell astrocytoma 2,230 | 2,230
tuberculosis 1,963 | 1,963
pituitary cancer 1,915 | 1,915
pancreatic ductal adenocarcinoma liver metastasis 1,911 | 1,911
Pick disease 1,856 | 1,856
group 4 medulloblastoma 1,806 | 1,806
ulcerative colitis 1,765 | 1,765
ductal carcinoma in situ 1,686 | 1,686
diabetes mellitus 1,683 | 1,683
cystic fibrosis 1,629 | 1,629
breast carcinoma 1,589 | 1,589
colon cancer 1,428 | 1,428
Autosomal recessive predisposition 1,407 | 1,407
adrenocortical carcinoma 1,385 | 1,385
Multiple myeloma 1,296 | 1,296
Rheumatoid arthritis 1,156 | 1,156
juvenile dermatomyositis 1,147 | 1,147
Schizophrenia 1,136 | 1,136
acute quadriplegic myopathy 1,133 | 1,133
astrocytoma 1,113 | 1,113
primary pancreatic ductal adenocarcinoma 1,071 | 1,071
spina bifida 1,053 | 1,053
pediatric high grade glioma 1,035 | 1,035
nasopharyngeal carcinoma 1,024 | 1,024
cutaneous lupus erythematosus 1,016 | 1,016
Intellectual disability 998 | 998
dermatomyositis 941 | 941
Atopic dermatitis 915 | 915
active Crohn's disease 882 | 882
non primary Sjogren syndrome sicca 861 | 861
gastric carcinoma 781 | 781
Epilepsy 775 | 775
acute myeloid leukemia 760 | 760
Waldenstrons macroglobulinemia 742 | 742
active ulcerative colitis 736 | 736
Liver Cirrhosis, Experimental 733 | 733
primary Sjogren syndrome 710 | 710
medulloblastoma 702 | 702
esophageal adenocarcinoma 696 | 696
Melanoma 689 | 689
progressive supranuclear palsy 656 | 656
Obesity 655 | 655
Bipolar Disorder 646 | 646
aldosterone-producing adenoma 646 | 646
Alzheimer's disease 640 | 640
Dull intelligence 634 | 634
Low intelligence 634 | 634
Mental Retardation 634 | 634
Mental deficiency 634 | 634
Poor school performance 634 | 634
Cognitive delay 596 | 596
Global developmental delay 596 | 596
Mental and motor retardation 596 | 596
Liver cancer 589 | 589
Duchenne muscular dystrophy 587 | 587
Seizures 584 | 584
Muscle hypotonia 562 | 562
pancreatic carcinoma 555 | 555
fibroadenoma 538 | 538
hepatocellular carcinoma 536 | 536
Multiple Sclerosis 527 | 527
Endometriosis 521 | 521
Short stature 514 | 514
chronic rhinosinusitis 505 | 505
autosomal dominant Emery-Dreifuss muscular dystrophy 492 | 492
Down syndrome 480 | 480
mucosa-associated lymphoid tissue lymphoma 473 | 473
Prostatic Neoplasms 472 | 472
sonic hedgehog group medulloblastoma 459 | 459
posterior fossa group A ependymoma 456 | 456
Skin cancer 451 | 451
gastric cancer 445 | 445

Tissue

Digestive Tract 286 | 17,369
Endocrine System 286 | 18,159
Female tissues 285 | 17,400
Skin and soft tissues 285 | 17,230
Urinary Tract 285 | 16,678
Blood and immune system 284 | 16,909
Liver and Pancreas 284 | 16,750
Male tissues 284 | 17,142
Respiratory system 284 | 16,393
Nervous System 281 | 16,725
Cardiovascular System 275 | 15,192

Target Family

Non-IDG 196 | 12,091
Enzyme 54 | 4,145
Transcription Factor 10 | 1,400
Kinase 9 | 634
Transporter 5 | 473
Ion Channel 4 | 344
Epigenetic 3 | 242
GPCR 3 | 408
TF/Epigenetic 2 | 38
Nuclear Receptor 1 | 48

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Docking protein 5 DOK5 Tbio Non-IDG -1.04456 11.4 284
Keratin, type I cytoskeletal 17 KRT17 Tbio Non-IDG -2.43909 265.8 711
Rho-related GTP-binding protein RhoU RHOU Tbio Enzyme -1.30084 24.8 95
ATP-dependent RNA helicase DDX3X DDX3X Tchem Enzyme -2.32036 221.7 479
Uncharacterized protein C6orf62 C6orf62 Tdark Non-IDG 0.57 0.18 105
Rho GTPase-activating protein 21 ARHGAP21 Tbio Enzyme -0.88944 9.45 20
Cathepsin Z CTSZ Tchem Enzyme -1.80363 70.2 233
MORC family CW-type zinc finger protein 3 MORC3 Tbio Non-IDG -1.61241 36.6 61
Nuclear receptor subfamily 4 group A member 2 NR4A2 Tchem Nuclear Receptor -2.59490 415.4 307
Protein enabled homolog ENAH Tbio Non-IDG -1.02502 9.91 150