Development Level

Tbio 197 | 10,625
Tchem 55 | 1,890
Tdark 29 | 7,003
Tclin 10 | 602

Collection

Eligible Ion Channel Proteins 1 | 117
Eligible Kinase Proteins 1 | 134

IMPC Term

preweaning lethality, complete... 11 | 633
abnormal behavior 7 | 226
preweaning lethality, incomple... 7 | 260
decreased lean body mass 6 | 195
increased or absent threshold ... 6 | 128
abnormal retina morphology 5 | 100
decreased total body fat amoun... 5 | 186
decreased body weight 4 | 174
decreased bone mineral content 4 | 157
decreased bone mineral density 4 | 126
decreased circulating serum al... 4 | 79
embryonic lethality prior to o... 4 | 148
increased lean body mass 4 | 107
abnormal spleen morphology 3 | 36
abnormal tooth morphology 3 | 24
decreased circulating HDL chol... 3 | 77
decreased circulating iron lev... 3 | 25
decreased circulating total pr... 3 | 41
decreased circulating triglyce... 3 | 83
decreased grip strength 3 | 123
decreased lumbar vertebrae num... 3 | 62
decreased startle reflex 3 | 48
enlarged heart 3 | 111
impaired glucose tolerance 3 | 52
increased fasted circulating g... 3 | 68
increased grip strength 3 | 83
increased mean corpuscular hem... 3 | 93
increased mean corpuscular vol... 3 | 91
increased sacral vertebrae num... 3 | 62
short tibia 3 | 82
abnormal QRS complex 2 | 25
abnormal bone structure 2 | 131
abnormal brain morphology 2 | 6
abnormal cranium morphology 2 | 32
abnormal embryo size 2 | 112
abnormal heart morphology 2 | 51
abnormal lens morphology 2 | 73
abnormal rib morphology 2 | 28
abnormal seminal vesicle morph... 2 | 47
abnormal sleep behavior 2 | 63
abnormal snout morphology 2 | 18
absent startle reflex 2 | 15
decreased body length 2 | 108
decreased circulating aspartat... 2 | 27
decreased circulating choleste... 2 | 85
decreased circulating glucose ... 2 | 121
decreased circulating insulin ... 2 | 75
decreased mean corpuscular vol... 2 | 50
embryonic lethality prior to t... 2 | 187
hyperactivity 2 | 108
hypoactivity 2 | 89
improved glucose tolerance 2 | 56
increased blood urea nitrogen ... 2 | 44
increased bone mineral content 2 | 92
increased bone mineral density 2 | 52
increased circulating alkaline... 2 | 119
increased circulating iron lev... 2 | 25
increased leukocyte cell numbe... 2 | 37
vertebral transformation 2 | 12
abnormal behavioral response t... 1 | 52
abnormal coping response 1 | 12
abnormal eye morphology 1 | 38
abnormal eye size 1 | 11
abnormal neural tube closure 1 | 37
abnormal neural tube morpholog... 1 | 8
abnormal retinal blood vessel ... 1 | 18
abnormal retinal pigmentation 1 | 61
abnormal skin morphology 1 | 23
abnormal vocalization 1 | 21
convulsive seizures 1 | 11
decreased caudal vertebrae num... 1 | 49
decreased circulating bilirubi... 1 | 14
decreased circulating phosphat... 1 | 15
decreased eosinophil cell numb... 1 | 41
decreased exploration in new e... 1 | 9
decreased heart weight 1 | 44
decreased hematocrit 1 | 25
decreased hemoglobin content 1 | 53
decreased mean corpuscular hem... 1 | 34
decreased threshold for audito... 1 | 32
decreased total retina thickne... 1 | 20
decreased vertical activity 1 | 22
dilated heart left ventricle 1 | 10
enlarged spleen 1 | 26
hydrops fetalis 1 | 22
increased CD4-positive, CD25-p... 1 | 18
increased NK T cell number 1 | 11
increased body length 1 | 20
increased caudal vertebrae num... 1 | 8
increased circulating HDL chol... 1 | 63
increased circulating alanine ... 1 | 11
increased circulating serum al... 1 | 25
increased circulating triglyce... 1 | 24
increased eosinophil cell numb... 1 | 9
increased gamma-delta T cell n... 1 | 16
increased rib number 1 | 41
microphthalmia 1 | 15
persistence of hyaloid vascula... 1 | 22
polycystic kidney 1 | 9
prenatal lethality prior to he... 1 | 64

Disease

interstitial lung disease 291 | 291
ovarian cancer 8,484 | 8,484
osteosarcoma 7,933 | 7,933
psoriasis 6,685 | 6,685
medulloblastoma, large-cell 6,234 | 6,234
glioblastoma 5,572 | 5,572
lung cancer 4,466 | 4,466
atypical teratoid / rhabdoid tumor 4,369 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 3,289 | 3,289
malignant mesothelioma 3,162 | 3,162
Breast cancer 3,094 | 3,094
pilocytic astrocytoma 3,086 | 3,086
primitive neuroectodermal tumor 3,031 | 3,031
intraductal papillary-mucinous carcinoma (IPMC) 2,988 | 2,988
intraductal papillary-mucinous adenoma (IPMA) 2,956 | 2,956
invasive ductal carcinoma 2,950 | 2,950
oligodendroglioma 2,849 | 2,849
lung carcinoma 2,844 | 2,844
non-small cell lung cancer 2,798 | 2,798
lung adenocarcinoma 2,713 | 2,713
pediatric high grade glioma 2,712 | 2,712
ependymoma 2,514 | 2,514
Cancer 2,346 | 2,346
pancreatic cancer 2,300 | 2,300
interstitial cystitis 2,299 | 2,299
subependymal giant cell astrocytoma 2,287 | 2,287
group 3 medulloblastoma 2,254 | 2,254
astrocytic glioma 2,241 | 2,241
adult high grade glioma 2,148 | 2,148
Carcinoma 2,147 | 2,147
ulcerative colitis 2,087 | 2,087
pituitary cancer 1,972 | 1,972
Pick disease 1,893 | 1,893
group 4 medulloblastoma 1,875 | 1,875
pancreatic ductal adenocarcinoma liver metastasis 1,795 | 1,795
ductal carcinoma in situ 1,745 | 1,745
cystic fibrosis 1,665 | 1,665
diabetes mellitus 1,663 | 1,663
breast carcinoma 1,614 | 1,614
tuberculosis 1,557 | 1,557
posterior fossa group B ependymoma 1,530 | 1,530
medulloblastoma 1,524 | 1,524
posterior fossa group A ependymoma 1,511 | 1,511
astrocytoma 1,493 | 1,493
sonic hedgehog group medulloblastoma 1,482 | 1,482
colon cancer 1,475 | 1,475
adrenocortical carcinoma 1,427 | 1,427
Multiple myeloma 1,327 | 1,327
primary pancreatic ductal adenocarcinoma 1,271 | 1,271
juvenile dermatomyositis 1,189 | 1,189
Rheumatoid Arthritis 1,160 | 1,160
acute quadriplegic myopathy 1,157 | 1,157
atypical teratoid/rhabdoid tumor 1,095 | 1,095
spina bifida 1,064 | 1,064
cutaneous lupus erythematosus 1,056 | 1,056
nasopharyngeal carcinoma 1,056 | 1,056
Atopic dermatitis 944 | 944
dermatomyositis 933 | 933
active Crohn's disease 918 | 918
non primary Sjogren syndrome sicca 840 | 840
gastric carcinoma 832 | 832
primary Sjogren syndrome 789 | 789
acute myeloid leukemia 780 | 780
Waldenstrons macroglobulinemia 765 | 765
esophageal adenocarcinoma 737 | 737
tuberculosis and treatment for 6 months 686 | 686
progressive supranuclear palsy 674 | 674
aldosterone-producing adenoma 664 | 664
Alzheimer's disease 644 | 644
Obesity 616 | 616
Duchenne muscular dystrophy 602 | 602
Intellectual disability 573 | 573
pancreatic carcinoma 567 | 567
fibroadenoma 557 | 557
Down syndrome 548 | 548
Endometriosis 535 | 535
hepatocellular carcinoma 532 | 532
chronic rhinosinusitis 512 | 512
Schizophrenia 501 | 501
autosomal dominant Emery-Dreifuss muscular dystrophy 499 | 499
Multiple Sclerosis 498 | 498
mucosa-associated lymphoid tissue lymphoma 480 | 480
active ulcerative colitis 477 | 477
Prostatic Neoplasms 471 | 471
IGA Glomerulonephritis 454 | 454
Amyotrophic Lateral Sclerosis 431 | 431
gastric cancer 430 | 430
non-small cell lung carcinoma 413 | 413
Mammary Neoplasms 410 | 410
inflammatory breast cancer 404 | 404
Kidney disease 396 | 396
Neurodegenerative disease 383 | 383
Parkinson's disease 364 | 364
sarcoidosis 358 | 358
Asthma 349 | 349
glioblastoma multiforme 347 | 347
Epilepsy 346 | 346
Polycystic Ovary Syndrome 332 | 332
nephrosclerosis 329 | 329
tuberculosis and treatment for 3 months 327 | 327
Autistic Disorder 320 | 320

Tissue

Urinary Tract 291 | 18,444
Cardiovascular System 290 | 17,958
Digestive Tract 290 | 18,473
Respiratory system 290 | 17,484
Blood and immune system 289 | 17,995
Liver and Pancreas 289 | 18,136
Male tissues 289 | 17,969
Nervous System 289 | 18,561
Endocrine System 288 | 18,512
Female tissues 288 | 18,647
Skin and soft tissues 287 | 18,115

Target Family

Non-IDG 198 | 11,971
Enzyme 55 | 4,146
Kinase 10 | 634
Transcription Factor 10 | 1,400
Transporter 5 | 473
Ion Channel 4 | 341
Epigenetic 3 | 242
GPCR 3 | 406
TF/Epigenetic 2 | 38
Nuclear Receptor 1 | 48

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
C-reactive protein CRP Tbio Non-IDG -4.51399 33883.5 1160
Mucin-1 MUC1 Tbio Non-IDG -3.49560 3532.0 1851
Desmoplakin DSP Tbio Non-IDG -2.90088 786.5 167
Dimethylaniline monooxygenase [N-oxide-forming] 5 FMO5 Tbio Enzyme -0.93021 9.11 128
Nuclear autoantigenic sperm protein NASP Tbio Non-IDG -1.72078 58.3 103
Pyruvate kinase PKM PKM Tchem Kinase -3.09101 1313.5 672
Calcium/calmodulin-dependent protein kinase type 1D CAMK1D Tchem Kinase -1.06137 12.5 282
Protein FAM83F FAM83F Tdark Non-IDG 0.00000 1.08 59
Neuroblast differentiation-associated protein AHNAK AHNAK Tbio Non-IDG -1.61845 51.3 82
Krueppel-like factor 9 KLF9 Tbio Transcription Factor -1.87911 88.8 139