Development Level

Tbio 1,472 | 11,178
Tdark 329 | 6,569
Tchem 315 | 1,885
Tclin 121 | 612

Collection

GPCR: IDG Consortium (Targets) 17 | 126
Ion Channel: IDG Consortium (T... 10 | 99
GPCR: IDG Consortium (Complete... 7 | 25
Kinase: IDG Consortium (Comple... 7 | 37
Kinase: IDG Consortium (Target... 7 | 125

IMPC Phenotype

preweaning lethality, incomple... 79 | 499
preweaning lethality, complete... 70 | 979
enlarged heart 40 | 210
decreased vertical activity 33 | 208
decreased total body fat amoun... 31 | 207
abnormal behavior 30 | 298
abnormal embryo size 29 | 220
abnormal heart morphology 27 | 162
embryonic lethality prior to t... 26 | 278
cataract 24 | 92
abnormal seminal vesicle morph... 23 | 114
increased lean body mass 23 | 172
abnormal bone structure 21 | 187
increased or absent threshold ... 21 | 101
abnormal lens morphology 20 | 81
decreased lymphocyte cell numb... 20 | 83
hypoactivity 20 | 132
decreased body weight 19 | 161
decreased bone mineral content 17 | 151
embryonic lethality prior to o... 17 | 239
increased monocyte cell number 17 | 63
abnormal skin morphology 16 | 50
increased bone mineral content 16 | 108
small superior vagus ganglion 16 | 74
abnormal kidney morphology 15 | 65
decreased mean corpuscular vol... 15 | 79
decreased startle reflex 15 | 75
decreased circulating serum al... 14 | 82
decreased grip strength 14 | 116
decreased leukocyte cell numbe... 14 | 73
decreased prepulse inhibition 14 | 82
hyperactivity 14 | 148
increased startle reflex 14 | 112
abnormal sleep behavior 13 | 70
impaired glucose tolerance 13 | 75
increased total body fat amoun... 13 | 134
decreased circulating glucose ... 12 | 126
hydrometra 12 | 53
increased fasted circulating g... 12 | 76
increased mean corpuscular hem... 12 | 96
decreased bone mineral density 11 | 126
decreased circulating insulin ... 11 | 76
decreased hemoglobin content 11 | 68
increased neutrophil cell numb... 11 | 46
short tibia 11 | 97
abnormal coat-hair pigmentatio... 10 | 64
decreased circulating choleste... 10 | 93
decreased fasted circulating g... 10 | 65
decreased lean body mass 10 | 135
improved glucose tolerance 10 | 79
increased circulating alkaline... 10 | 122
increased circulating triglyce... 10 | 42
increased mean corpuscular vol... 10 | 92
male infertility 10 | 123
abnormal eye morphology 9 | 68
abnormal retina morphology 9 | 71
abnormal spleen morphology 9 | 55
decreased body length 9 | 101
decreased circulating triglyce... 9 | 79
decreased erythrocyte cell num... 9 | 62
decreased mean corpuscular hem... 9 | 50
increased circulating HDL chol... 9 | 80
increased erythrocyte cell num... 9 | 39
increased heart weight 9 | 62
small testis 9 | 58
thrombocytopenia 9 | 56
abnormal behavioral response t... 8 | 66
abnormal epididymis morphology 8 | 42
abnormal gait 8 | 69
abnormal testis morphology 8 | 43
decreased blood urea nitrogen ... 8 | 51
decreased circulating total pr... 8 | 49
decreased hematocrit 8 | 46
impaired righting response 8 | 26
increased blood urea nitrogen ... 8 | 48
increased bone mineral density 8 | 72
limb grasping 8 | 41
abnormal coat appearance 7 | 31
decreased circulating HDL chol... 7 | 68
decreased circulating alkaline... 7 | 46
decreased threshold for audito... 7 | 26
increased body weight 7 | 25
increased circulating choleste... 7 | 66
prenatal lethality prior to he... 7 | 87
absent startle reflex 6 | 24
decreased circulating bilirubi... 6 | 19
decreased circulating potassiu... 6 | 20
decreased red blood cell distr... 6 | 41
embryonic growth retardation 6 | 106
enlarged lymph nodes 6 | 37
female infertility 6 | 60
increased body length 6 | 32
increased circulating calcium ... 6 | 34
increased circulating potassiu... 6 | 29
increased circulating sodium l... 6 | 71
increased mean platelet volume 6 | 45
increased vertical activity 6 | 24
corneal opacity 5 | 32
decreased circulating iron lev... 5 | 32
increased prepulse inhibition 5 | 32

Disease

interstitial cystitis 2,237 | 2,237
Carcinoma 11,192 | 11,192
ovarian cancer 8,297 | 8,297
osteosarcoma 7,766 | 7,766
psoriasis 6,514 | 6,514
medulloblastoma, large-cell 6,086 | 6,086
glioblastoma 5,635 | 5,635
atypical teratoid / rhabdoid tumor 4,971 | 4,971
lung cancer 4,607 | 4,607
ependymoma 4,559 | 4,559
group 3 medulloblastoma 4,002 | 4,002
adult high grade glioma 3,701 | 3,701
Breast cancer 3,469 | 3,469
intraductal papillary-mucinous neoplasm (IPMN) 3,204 | 3,204
malignant mesothelioma 3,135 | 3,135
Astrocytoma, Pilocytic 3,006 | 3,006
primitive neuroectodermal tumor 2,957 | 2,957
intraductal papillary-mucinous carcinoma (IPMC) 2,902 | 2,902
intraductal papillary-mucinous adenoma (IPMA) 2,872 | 2,872
invasive ductal carcinoma 2,867 | 2,867
non-small cell lung cancer 2,799 | 2,799
oligodendroglioma 2,768 | 2,768
lung carcinoma 2,755 | 2,755
lung adenocarcinoma 2,627 | 2,627
Kidney cancer 2,548 | 2,548
astrocytic glioma 2,530 | 2,530
Cancer 2,388 | 2,388
pancreatic cancer 2,322 | 2,322
subependymal giant cell astrocytoma 2,230 | 2,230
tuberculosis 1,963 | 1,963
pituitary cancer 1,915 | 1,915
pancreatic ductal adenocarcinoma liver metastasis 1,911 | 1,911
Pick disease 1,856 | 1,856
group 4 medulloblastoma 1,806 | 1,806
ulcerative colitis 1,765 | 1,765
ductal carcinoma in situ 1,686 | 1,686
diabetes mellitus 1,683 | 1,683
cystic fibrosis 1,629 | 1,629
breast carcinoma 1,589 | 1,589
colon cancer 1,428 | 1,428
Autosomal recessive predisposition 1,407 | 1,407
adrenocortical carcinoma 1,385 | 1,385
Multiple myeloma 1,296 | 1,296
Rheumatoid arthritis 1,156 | 1,156
juvenile dermatomyositis 1,147 | 1,147
Schizophrenia 1,136 | 1,136
acute quadriplegic myopathy 1,133 | 1,133
astrocytoma 1,113 | 1,113
primary pancreatic ductal adenocarcinoma 1,071 | 1,071
spina bifida 1,053 | 1,053
pediatric high grade glioma 1,035 | 1,035
nasopharyngeal carcinoma 1,024 | 1,024
cutaneous lupus erythematosus 1,016 | 1,016
Intellectual disability 998 | 998
dermatomyositis 941 | 941
Atopic dermatitis 915 | 915
active Crohn's disease 882 | 882
non primary Sjogren syndrome sicca 861 | 861
gastric carcinoma 781 | 781
Epilepsy 775 | 775
acute myeloid leukemia 760 | 760
Waldenstrons macroglobulinemia 742 | 742
active ulcerative colitis 736 | 736
Liver Cirrhosis, Experimental 733 | 733
primary Sjogren syndrome 710 | 710
medulloblastoma 702 | 702
esophageal adenocarcinoma 696 | 696
Melanoma 689 | 689
progressive supranuclear palsy 656 | 656
Obesity 655 | 655
Bipolar Disorder 646 | 646
aldosterone-producing adenoma 646 | 646
Alzheimer's disease 640 | 640
Dull intelligence 634 | 634
Low intelligence 634 | 634
Mental Retardation 634 | 634
Mental deficiency 634 | 634
Poor school performance 634 | 634
Cognitive delay 596 | 596
Global developmental delay 596 | 596
Mental and motor retardation 596 | 596
Liver cancer 589 | 589
Duchenne muscular dystrophy 587 | 587
Seizures 584 | 584
Muscle hypotonia 562 | 562
pancreatic carcinoma 555 | 555
fibroadenoma 538 | 538
hepatocellular carcinoma 536 | 536
Multiple Sclerosis 527 | 527
Endometriosis 521 | 521
Short stature 514 | 514
chronic rhinosinusitis 505 | 505
autosomal dominant Emery-Dreifuss muscular dystrophy 492 | 492
Down syndrome 480 | 480
mucosa-associated lymphoid tissue lymphoma 473 | 473
Prostatic Neoplasms 472 | 472
sonic hedgehog group medulloblastoma 459 | 459
posterior fossa group A ependymoma 456 | 456
Skin cancer 451 | 451
gastric cancer 445 | 445

Tissue

Digestive Tract 2,195 | 17,369
Female tissues 2,188 | 17,400
Endocrine System 2,187 | 18,159
Urinary Tract 2,187 | 16,678
Male tissues 2,185 | 17,142
Skin and soft tissues 2,184 | 17,230
Blood and immune system 2,169 | 16,909
Liver and Pancreas 2,168 | 16,750
Respiratory system 2,162 | 16,393
Nervous System 2,125 | 16,725
Cardiovascular System 2,038 | 15,192

Target Family

Non-IDG 1,348 | 12,091
Enzyme 459 | 4,145
Transcription Factor 141 | 1,400
Kinase 88 | 634
GPCR 75 | 408
Transporter 58 | 473
Ion Channel 42 | 344
Nuclear Receptor 12 | 48
Epigenetic 8 | 242
TF/Epigenetic 4 | 38
oGPCR 2 | 421

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Nidogen-2 NID2 Tbio Non-IDG -1.62355 40.1 116
MyoD family inhibitor domain-containing protein MDFIC Tbio Non-IDG -2.90969 749.0 122
T-lymphocyte activation antigen CD80 CD80 Tclin Non-IDG -3.39216 2405.6 1323
Prominin-2 PROM2 Tbio Non-IDG -1.12562 11.0 199
Neutrophil gelatinase-associated lipocalin LCN2 Tbio Enzyme -3.35178 2368.1 847
Nck-associated protein 1-like NCKAP1L Tbio Non-IDG -1.07556 11.2 127
E3 ubiquitin-protein ligase MARCH1 MARCH1 Tbio Enzyme -2.08811 122.3 133
Tumor necrosis factor receptor superfamily member 1B TNFRSF1B Tchem Non-IDG -3.67481 4484.7 712
Protein NKG7 NKG7 Tdark Non-IDG -0.96689 9.71 14
Pantothenate kinase 1 PANK1 Tbio Kinase -1.80926 56.9 188