Development Level

Tbio 365 | 11,651
Tdark 95 | 6,593
Tchem 65 | 1,388
Tclin 22 | 612

Collection

Kinase: IDG Consortium (Target... 3 | 125
Kinase: IDG Consortium (Comple... 2 | 37
GPCR: IDG Consortium (Targets) 1 | 126
Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

preweaning lethality, complete... 39 | 979
embryonic lethality prior to t... 16 | 278
embryonic lethality prior to o... 14 | 239
preweaning lethality, incomple... 13 | 499
decreased lymphocyte cell numb... 8 | 83
enlarged heart 8 | 210
abnormal behavior 7 | 298
abnormal heart morphology 7 | 162
decreased total body fat amoun... 7 | 207
decreased vertical activity 7 | 208
abnormal seminal vesicle morph... 6 | 114
decreased body weight 6 | 161
increased neutrophil cell numb... 6 | 46
increased startle reflex 6 | 112
abnormal bone structure 5 | 187
abnormal embryo size 5 | 220
decreased hemoglobin content 5 | 68
increased circulating alkaline... 5 | 122
increased monocyte cell number 5 | 63
abnormal lens morphology 4 | 81
abnormal retina morphology 4 | 71
cataract 4 | 92
decreased bone mineral content 4 | 151
decreased bone mineral density 4 | 126
decreased circulating triglyce... 4 | 79
decreased lean body mass 4 | 135
decreased leukocyte cell numbe... 4 | 73
decreased mean corpuscular vol... 4 | 79
increased heart weight 4 | 62
increased mean corpuscular vol... 4 | 92
increased total body fat amoun... 4 | 134
male infertility 4 | 123
thrombocytopenia 4 | 56
abnormal coat-hair pigmentatio... 3 | 64
abnormal kidney morphology 3 | 65
abnormal lung morphology 3 | 26
abnormal retinal vasculature m... 3 | 27
abnormal skin morphology 3 | 50
abnormal spleen morphology 3 | 55
decreased body length 3 | 101
decreased circulating HDL chol... 3 | 68
decreased circulating alanine ... 3 | 47
decreased circulating amylase ... 3 | 28
decreased circulating choleste... 3 | 93
decreased heart left ventricle... 3 | 28
decreased hematocrit 3 | 46
decreased mean corpuscular hem... 3 | 50
decreased prepulse inhibition 3 | 82
decreased red blood cell distr... 3 | 41
decreased spleen weight 3 | 10
decreased threshold for audito... 3 | 26
female infertility 3 | 60
improved glucose tolerance 3 | 79
increased bone mineral content 3 | 108
increased circulating HDL chol... 3 | 80
increased circulating calcium ... 3 | 34
increased circulating choleste... 3 | 66
increased lean body mass 3 | 172
increased or absent threshold ... 3 | 101
increased prepulse inhibition 3 | 32
prenatal lethality prior to he... 3 | 87
abnormal bone mineralization 2 | 38
abnormal cecum morphology 2 | 7
abnormal eye morphology 2 | 68
abnormal neural tube closure 2 | 46
abnormal neural tube morpholog... 2 | 12
abnormal retinal blood vessel ... 2 | 26
abnormal sleep behavior 2 | 70
corneal opacity 2 | 32
decreased blood urea nitrogen ... 2 | 51
decreased circulating bilirubi... 2 | 19
decreased circulating glucose ... 2 | 126
decreased circulating insulin ... 2 | 76
decreased circulating serum al... 2 | 82
decreased circulating total pr... 2 | 49
decreased heart weight 2 | 27
decreased mean corpuscular hem... 2 | 31
edema 2 | 59
enlarged kidney 2 | 14
enlarged seminal vesicle 2 | 10
hyperactivity 2 | 148
hypoactivity 2 | 132
increased anti-nuclear antigen... 2 | 19
increased blood urea nitrogen ... 2 | 48
increased body length 2 | 32
increased bone mineral density 2 | 72
increased circulating total pr... 2 | 28
increased circulating triglyce... 2 | 42
increased eosinophil cell numb... 2 | 11
increased erythrocyte cell num... 2 | 39
increased fasted circulating g... 2 | 76
increased mean corpuscular hem... 2 | 96
polycystic kidney 2 | 15
prolonged ST segment 2 | 36
thin ventricular wall 2 | 24
abnormal craniofacial morpholo... 1 | 33
abnormal ear morphology 1 | 9
enlarged spleen 1 | 41
increased circulating iron lev... 1 | 30
vertebral fusion 1 | 23

Disease

hepatocellular carcinoma 547 | 547
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Endocrine System 542 | 18,159
Liver and Pancreas 541 | 16,750
Skin and soft tissues 541 | 17,230
Urinary Tract 541 | 16,678
Blood and immune system 540 | 16,909
Digestive Tract 540 | 17,369
Female tissues 539 | 17,400
Male tissues 537 | 17,142
Respiratory system 537 | 16,393
Nervous System 536 | 16,725
Cardiovascular System 530 | 15,192

Target Family

Non-IDG 309 | 12,091
Enzyme 137 | 4,145
Transcription Factor 47 | 1,400
Kinase 16 | 634
GPCR 14 | 408
Transporter 10 | 473
Epigenetic 6 | 242
Ion Channel 4 | 344
Nuclear Receptor 2 | 48
TF/Epigenetic 2 | 38

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cellular tumor antigen p53 TP53 Tchem Transcription Factor -4.74112 54026.3 6298
Prothrombin F2 Tclin Enzyme -4.53745 33691.4 579
Interleukin-1 beta IL1B Tclin Non-IDG -4.40738 24522.4 1588
Vascular endothelial growth factor A VEGFA Tclin Non-IDG -4.27197 19076.6 1809