Development Level

Tbio 160 | 11,651
Tchem 48 | 1,388
Tdark 18 | 6,593
Tclin 13 | 612

Collection

RFA-RM-18-021 3 | 328
GPCR: IDG Consortium (Complete... 2 | 25
GPCR: IDG Consortium (Targets) 2 | 126

IMPC Phenotype

preweaning lethality, complete... 8 | 979
enlarged heart 6 | 210
abnormal heart morphology 5 | 162
cataract 5 | 92
increased mean corpuscular hem... 5 | 36
preweaning lethality, incomple... 5 | 499
decreased circulating glucose ... 4 | 126
decreased mean corpuscular vol... 4 | 79
decreased total body fat amoun... 4 | 207
decreased vertical activity 4 | 208
increased mean corpuscular hem... 4 | 96
abnormal behavior 3 | 298
abnormal embryo size 3 | 220
abnormal kidney morphology 3 | 65
abnormal lens morphology 3 | 81
abnormal seminal vesicle morph... 3 | 114
embryonic lethality prior to t... 3 | 278
increased circulating alkaline... 3 | 122
increased circulating sodium l... 3 | 71
increased erythrocyte cell num... 3 | 39
abnormal coat-hair pigmentatio... 2 | 64
abnormal sleep behavior 2 | 70
decreased circulating insulin ... 2 | 76
decreased circulating serum al... 2 | 82
decreased circulating sodium l... 2 | 22
decreased erythrocyte cell num... 2 | 62
decreased fasted circulating g... 2 | 65
decreased grip strength 2 | 116
decreased hematocrit 2 | 46
decreased lean body mass 2 | 135
decreased leukocyte cell numbe... 2 | 73
decreased lymphocyte cell numb... 2 | 83
decreased mean corpuscular hem... 2 | 50
decreased neutrophil cell numb... 2 | 42
hydrometra 2 | 53
hyperactivity 2 | 148
hypoactivity 2 | 132
impaired righting response 2 | 26
increased blood urea nitrogen ... 2 | 48
increased bone mineral content 2 | 108
increased bone mineral density 2 | 72
increased circulating HDL chol... 2 | 80
increased circulating chloride... 2 | 41
increased heart weight 2 | 62
increased neutrophil cell numb... 2 | 46
increased total body fat amoun... 2 | 134
short tibia 2 | 97
small superior vagus ganglion 2 | 74
abnormal behavioral response t... 1 | 66
abnormal body wall morphology 1 | 9
abnormal epididymis morphology 1 | 42
abnormal gait 1 | 69
abnormal liver morphology 1 | 17
abnormal lung morphology 1 | 26
abnormal optic disc morphology 1 | 10
abnormal retina morphology 1 | 71
abnormal retinal vasculature m... 1 | 27
abnormal spine curvature 1 | 9
abnormal tooth morphology 1 | 24
abnormal vitreous body morphol... 1 | 10
cardiovascular system phenotyp... 1 | 36
decreased blood urea nitrogen ... 1 | 51
decreased bone mineral content 1 | 151
decreased circulating HDL chol... 1 | 68
decreased circulating bilirubi... 1 | 19
decreased circulating creatini... 1 | 39
decreased circulating iron lev... 1 | 32
decreased heart rate variabili... 1 | 13
decreased hemoglobin content 1 | 68
decreased mean corpuscular hem... 1 | 31
decreased prepulse inhibition 1 | 82
decreased spleen weight 1 | 10
decreased startle reflex 1 | 75
dilated heart left ventricle 1 | 11
edema 1 | 59
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
enlarged epididymis 1 | 31
enlarged lymph nodes 1 | 37
enlarged uterus 1 | 11
increased circulating alanine ... 1 | 13
increased circulating bilirubi... 1 | 16
increased circulating choleste... 1 | 66
increased circulating free fat... 1 | 20
increased circulating glucose ... 1 | 24
increased circulating potassiu... 1 | 29
increased circulating triglyce... 1 | 42
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased or absent threshold ... 1 | 101
increased prepulse inhibition 1 | 32
increased red blood cell distr... 1 | 34
increased startle reflex 1 | 112
increased vertical activity 1 | 24
microphthalmia 1 | 26
premature death 1 | 5
thin ventricular wall 1 | 24
tremors 1 | 39

Disease

head and neck cancer and chronic obstructive pulmonary disease 239 | 239
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Digestive Tract 235 | 17,369
Female tissues 235 | 17,400
Endocrine System 234 | 18,159
Skin and soft tissues 234 | 17,230
Respiratory system 232 | 16,393
Blood and immune system 231 | 16,909
Liver and Pancreas 230 | 16,750
Male tissues 230 | 17,142
Urinary Tract 229 | 16,678
Nervous System 225 | 16,725
Cardiovascular System 211 | 15,192

Target Family

Non-IDG 135 | 12,091
Enzyme 67 | 4,145
GPCR 12 | 408
Transcription Factor 9 | 1,400
Transporter 6 | 473
Kinase 5 | 634
Ion Channel 3 | 344
Epigenetic 1 | 242
Nuclear Receptor 1 | 48

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Galectin-2 LGALS2 Tbio Non-IDG -1.12300 13.4 172
Thrombospondin-1 THBS1 Tbio Non-IDG -3.06622 1281.6 504
A disintegrin and metalloproteinase with thrombospondin motifs 2 ADAMTS2 Tbio Enzyme -2.51717 1472.5 133
Tyrosine-protein kinase JAK3 JAK3 Tclin Kinase -2.64385 453.7 292
Aldehyde dehydrogenase, dimeric NADP-preferring ALDH3A1 Tchem Enzyme -2.12624 141.3 310
HEPACAM family member 2 HEPACAM2 Tbio Non-IDG -0.86200 6.23 109
C-C chemokine receptor type 2 CCR2 Tchem GPCR -3.06548 1112.4 530
Lebercilin LCA5 Tbio Non-IDG -1.24990 16.8 78
Collagen alpha-1(III) chain COL3A1 Tbio Non-IDG -2.58251 354.8 439
AP-2 complex subunit beta AP2B1 Tbio Non-IDG -1.59767 34.8 212