Development Level

Tbio 145 | 11,178
Tchem 51 | 1,885
Tdark 17 | 6,569
Tclin 13 | 612

Collection

GPCR: IDG Consortium (Complete... 2 | 25
GPCR: IDG Consortium (Targets) 2 | 126

IMPC Phenotype

preweaning lethality, complete... 8 | 979
enlarged heart 6 | 210
abnormal heart morphology 5 | 162
cataract 5 | 92
increased mean corpuscular hem... 5 | 36
decreased circulating glucose ... 4 | 126
decreased mean corpuscular vol... 4 | 79
decreased total body fat amoun... 4 | 207
decreased vertical activity 4 | 208
increased mean corpuscular hem... 4 | 96
preweaning lethality, incomple... 4 | 499
abnormal behavior 3 | 298
abnormal embryo size 3 | 220
abnormal kidney morphology 3 | 65
abnormal lens morphology 3 | 81
abnormal seminal vesicle morph... 3 | 114
embryonic lethality prior to t... 3 | 278
increased circulating alkaline... 3 | 122
increased circulating sodium l... 3 | 71
increased erythrocyte cell num... 3 | 39
abnormal coat-hair pigmentatio... 2 | 64
abnormal sleep behavior 2 | 70
decreased circulating insulin ... 2 | 76
decreased circulating serum al... 2 | 82
decreased circulating sodium l... 2 | 22
decreased erythrocyte cell num... 2 | 62
decreased fasted circulating g... 2 | 65
decreased grip strength 2 | 116
decreased hematocrit 2 | 46
decreased lean body mass 2 | 135
decreased leukocyte cell numbe... 2 | 73
decreased lymphocyte cell numb... 2 | 83
decreased mean corpuscular hem... 2 | 50
decreased neutrophil cell numb... 2 | 42
hydrometra 2 | 53
hyperactivity 2 | 148
hypoactivity 2 | 132
impaired righting response 2 | 26
increased bone mineral content 2 | 108
increased bone mineral density 2 | 72
increased circulating HDL chol... 2 | 80
increased circulating chloride... 2 | 41
increased heart weight 2 | 62
increased neutrophil cell numb... 2 | 46
increased total body fat amoun... 2 | 134
small superior vagus ganglion 2 | 74
abnormal behavioral response t... 1 | 66
abnormal body wall morphology 1 | 9
abnormal epididymis morphology 1 | 42
abnormal gait 1 | 69
abnormal liver morphology 1 | 17
abnormal lung morphology 1 | 26
abnormal optic disc morphology 1 | 10
abnormal retina morphology 1 | 71
abnormal retinal vasculature m... 1 | 27
abnormal sensory capabilities-... 1 | 8
abnormal spine curvature 1 | 9
abnormal tooth morphology 1 | 24
abnormal vitreous body morphol... 1 | 10
cardiovascular system phenotyp... 1 | 36
decreased blood urea nitrogen ... 1 | 51
decreased bone mineral content 1 | 151
decreased circulating HDL chol... 1 | 68
decreased circulating creatini... 1 | 39
decreased circulating iron lev... 1 | 32
decreased heart rate variabili... 1 | 13
decreased hemoglobin content 1 | 68
decreased mean corpuscular hem... 1 | 31
decreased prepulse inhibition 1 | 82
decreased spleen weight 1 | 10
decreased startle reflex 1 | 75
dilated heart left ventricle 1 | 11
edema 1 | 59
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
enlarged epididymis 1 | 31
enlarged lymph nodes 1 | 37
enlarged uterus 1 | 11
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased circulating alanine ... 1 | 13
increased circulating bilirubi... 1 | 16
increased circulating choleste... 1 | 66
increased circulating free fat... 1 | 20
increased circulating glucose ... 1 | 24
increased circulating potassiu... 1 | 29
increased circulating triglyce... 1 | 42
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased or absent threshold ... 1 | 101
increased prepulse inhibition 1 | 32
increased red blood cell distr... 1 | 34
increased startle reflex 1 | 112
increased vertical activity 1 | 24
microphthalmia 1 | 26
short tibia 1 | 97
thin ventricular wall 1 | 24
tremors 1 | 39

Disease

head and neck cancer and chronic obstructive pulmonary disease 226 | 226
Carcinoma 11,192 | 11,192
ovarian cancer 8,297 | 8,297
osteosarcoma 7,766 | 7,766
psoriasis 6,514 | 6,514
medulloblastoma, large-cell 6,086 | 6,086
glioblastoma 5,635 | 5,635
atypical teratoid / rhabdoid tumor 4,971 | 4,971
lung cancer 4,607 | 4,607
ependymoma 4,559 | 4,559
group 3 medulloblastoma 4,002 | 4,002
adult high grade glioma 3,701 | 3,701
Breast cancer 3,469 | 3,469
intraductal papillary-mucinous neoplasm (IPMN) 3,204 | 3,204
malignant mesothelioma 3,135 | 3,135
Astrocytoma, Pilocytic 3,006 | 3,006
primitive neuroectodermal tumor 2,957 | 2,957
intraductal papillary-mucinous carcinoma (IPMC) 2,902 | 2,902
intraductal papillary-mucinous adenoma (IPMA) 2,872 | 2,872
invasive ductal carcinoma 2,867 | 2,867
non-small cell lung cancer 2,799 | 2,799
oligodendroglioma 2,768 | 2,768
lung carcinoma 2,755 | 2,755
lung adenocarcinoma 2,627 | 2,627
Kidney cancer 2,548 | 2,548
astrocytic glioma 2,530 | 2,530
Cancer 2,388 | 2,388
pancreatic cancer 2,322 | 2,322
interstitial cystitis 2,237 | 2,237
subependymal giant cell astrocytoma 2,230 | 2,230
tuberculosis 1,963 | 1,963
pituitary cancer 1,915 | 1,915
pancreatic ductal adenocarcinoma liver metastasis 1,911 | 1,911
Pick disease 1,856 | 1,856
group 4 medulloblastoma 1,806 | 1,806
ulcerative colitis 1,765 | 1,765
ductal carcinoma in situ 1,686 | 1,686
diabetes mellitus 1,683 | 1,683
cystic fibrosis 1,629 | 1,629
breast carcinoma 1,589 | 1,589
colon cancer 1,428 | 1,428
Autosomal recessive predisposition 1,407 | 1,407
adrenocortical carcinoma 1,385 | 1,385
Multiple myeloma 1,296 | 1,296
Rheumatoid arthritis 1,156 | 1,156
juvenile dermatomyositis 1,147 | 1,147
Schizophrenia 1,136 | 1,136
acute quadriplegic myopathy 1,133 | 1,133
astrocytoma 1,113 | 1,113
primary pancreatic ductal adenocarcinoma 1,071 | 1,071
spina bifida 1,053 | 1,053
pediatric high grade glioma 1,035 | 1,035
nasopharyngeal carcinoma 1,024 | 1,024
cutaneous lupus erythematosus 1,016 | 1,016
Intellectual disability 998 | 998
dermatomyositis 941 | 941
Atopic dermatitis 915 | 915
active Crohn's disease 882 | 882
non primary Sjogren syndrome sicca 861 | 861
gastric carcinoma 781 | 781
Epilepsy 775 | 775
acute myeloid leukemia 760 | 760
Waldenstrons macroglobulinemia 742 | 742
active ulcerative colitis 736 | 736
Liver Cirrhosis, Experimental 733 | 733
primary Sjogren syndrome 710 | 710
medulloblastoma 702 | 702
esophageal adenocarcinoma 696 | 696
Melanoma 689 | 689
progressive supranuclear palsy 656 | 656
Obesity 655 | 655
Bipolar Disorder 646 | 646
aldosterone-producing adenoma 646 | 646
Alzheimer's disease 640 | 640
Dull intelligence 634 | 634
Low intelligence 634 | 634
Mental Retardation 634 | 634
Mental deficiency 634 | 634
Poor school performance 634 | 634
Cognitive delay 596 | 596
Global developmental delay 596 | 596
Mental and motor retardation 596 | 596
Liver cancer 589 | 589
Duchenne muscular dystrophy 587 | 587
Seizures 584 | 584
Muscle hypotonia 562 | 562
pancreatic carcinoma 555 | 555
fibroadenoma 538 | 538
hepatocellular carcinoma 536 | 536
Multiple Sclerosis 527 | 527
Endometriosis 521 | 521
Short stature 514 | 514
chronic rhinosinusitis 505 | 505
autosomal dominant Emery-Dreifuss muscular dystrophy 492 | 492
Down syndrome 480 | 480
mucosa-associated lymphoid tissue lymphoma 473 | 473
Prostatic Neoplasms 472 | 472
sonic hedgehog group medulloblastoma 459 | 459
posterior fossa group A ependymoma 456 | 456
Skin cancer 451 | 451
gastric cancer 445 | 445

Tissue

Digestive Tract 222 | 17,369
Female tissues 222 | 17,400
Skin and soft tissues 222 | 17,230
Endocrine System 221 | 18,159
Respiratory system 219 | 16,393
Blood and immune system 218 | 16,909
Liver and Pancreas 218 | 16,750
Male tissues 217 | 17,142
Urinary Tract 216 | 16,678
Nervous System 214 | 16,725
Cardiovascular System 201 | 15,192

Target Family

Non-IDG 133 | 12,091
Enzyme 56 | 4,145
GPCR 12 | 408
Transcription Factor 9 | 1,400
Transporter 6 | 473
Kinase 5 | 634
Ion Channel 3 | 344
Epigenetic 1 | 242
Nuclear Receptor 1 | 48

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Neutrophil gelatinase-associated lipocalin LCN2 Tbio Enzyme -3.35178 2368.1 847
Nck-associated protein 1-like NCKAP1L Tbio Non-IDG -1.07556 11.2 127
E3 ubiquitin-protein ligase MARCH1 MARCH1 Tbio Enzyme -2.08811 122.3 133
Ras-related protein Rab-3B RAB3B Tbio Enzyme -1.38932 26.8 121
P protein OCA2 Tbio Non-IDG -2.47946 286.8 125
CMRF35-like molecule 1 CD300LF Tbio Non-IDG -1.58161 43.4 183
Serum paraoxonase/lactonase 3 PON3 Tbio Enzyme -1.89828 64.7 182
Pirin PIR Tchem Non-IDG -2.72312 503.8 154
Allograft inflammatory factor 1 AIF1 Tbio Non-IDG -3.07876 1105.3 601
C-C motif chemokine 8 CCL8 Tbio Non-IDG -2.14856 127.9 298