Development Level

Tbio 2,623 | 11,178
Tdark 792 | 6,569
Tchem 428 | 1,885
Tclin 159 | 612

Collection

Ion Channel: IDG Consortium (T... 26 | 99
Kinase: IDG Consortium (Target... 18 | 125
GPCR: IDG Consortium (Targets) 8 | 126
Kinase: IDG Consortium (Comple... 6 | 37
GPCR: IDG Consortium (Complete... 3 | 25

IMPC Phenotype

preweaning lethality, complete... 258 | 979
preweaning lethality, incomple... 147 | 499
abnormal behavior 92 | 298
embryonic lethality prior to t... 78 | 278
decreased total body fat amoun... 64 | 207
embryonic lethality prior to o... 64 | 239
abnormal embryo size 59 | 220
decreased vertical activity 53 | 208
increased lean body mass 53 | 172
decreased body weight 50 | 161
abnormal bone structure 49 | 187
enlarged heart 49 | 210
hyperactivity 49 | 148
hypoactivity 43 | 132
increased bone mineral content 42 | 108
decreased bone mineral content 41 | 151
decreased lean body mass 39 | 135
decreased grip strength 37 | 116
increased startle reflex 37 | 112
increased total body fat amoun... 37 | 134
increased circulating alkaline... 35 | 122
abnormal heart morphology 33 | 162
decreased bone mineral density 33 | 126
male infertility 33 | 123
decreased circulating glucose ... 31 | 126
decreased circulating choleste... 30 | 93
decreased circulating serum al... 30 | 82
decreased startle reflex 28 | 75
cataract 26 | 92
prenatal lethality prior to he... 26 | 87
abnormal seminal vesicle morph... 25 | 114
decreased prepulse inhibition 25 | 82
embryonic growth retardation 25 | 106
increased or absent threshold ... 25 | 101
abnormal behavioral response t... 24 | 66
decreased circulating insulin ... 24 | 76
increased mean corpuscular hem... 24 | 96
increased mean corpuscular vol... 24 | 92
short tibia 24 | 97
decreased circulating HDL chol... 23 | 68
abnormal lens morphology 22 | 81
decreased body length 22 | 101
increased heart weight 22 | 62
decreased circulating triglyce... 20 | 79
decreased mean corpuscular vol... 20 | 79
abnormal sleep behavior 19 | 70
decreased hemoglobin content 19 | 68
decreased lymphocyte cell numb... 19 | 83
abnormal retina morphology 18 | 71
decreased leukocyte cell numbe... 18 | 73
improved glucose tolerance 18 | 79
increased bone mineral density 18 | 72
increased circulating HDL chol... 18 | 80
increased fasted circulating g... 18 | 76
increased monocyte cell number 18 | 63
abnormal gait 17 | 69
abnormal kidney morphology 17 | 65
abnormal spleen morphology 17 | 55
decreased fasted circulating g... 17 | 65
increased leukocyte cell numbe... 17 | 47
abnormal coat-hair pigmentatio... 16 | 64
abnormal eye morphology 16 | 68
decreased caudal vertebrae num... 16 | 53
increased hemoglobin content 16 | 45
small superior vagus ganglion 16 | 74
thrombocytopenia 16 | 56
decreased circulating total pr... 15 | 49
decreased mean corpuscular hem... 15 | 50
impaired glucose tolerance 15 | 75
increased circulating sodium l... 15 | 71
decreased blood urea nitrogen ... 14 | 51
edema 14 | 59
female infertility 14 | 60
increased circulating chloride... 14 | 41
increased circulating triglyce... 14 | 42
increased mean corpuscular hem... 14 | 36
tremors 14 | 39
decreased circulating LDL chol... 13 | 38
increased blood urea nitrogen ... 13 | 48
increased circulating creatini... 13 | 38
abnormal neural tube closure 12 | 46
abnormal skin morphology 12 | 50
increased circulating calcium ... 12 | 34
increased circulating choleste... 12 | 66
limb grasping 12 | 41
small testis 12 | 58
abnormal coat appearance 11 | 31
abnormal craniofacial morpholo... 11 | 33
abnormal cranium morphology 11 | 36
abnormal embryo turning 11 | 31
abnormal epididymis morphology 11 | 42
cardiovascular system phenotyp... 11 | 36
decreased circulating alanine ... 11 | 47
enlarged lymph nodes 11 | 37
enlarged spleen 11 | 41
increased grip strength 11 | 41
increased hematocrit 11 | 46
increased mean platelet volume 11 | 45
increased neutrophil cell numb... 11 | 46
prolonged ST segment 10 | 36

Disease

group 3 medulloblastoma 4,002 | 4,002
Carcinoma 11,192 | 11,192
ovarian cancer 8,297 | 8,297
osteosarcoma 7,766 | 7,766
psoriasis 6,514 | 6,514
medulloblastoma, large-cell 6,086 | 6,086
glioblastoma 5,635 | 5,635
atypical teratoid / rhabdoid tumor 4,971 | 4,971
lung cancer 4,607 | 4,607
ependymoma 4,559 | 4,559
adult high grade glioma 3,701 | 3,701
Breast cancer 3,469 | 3,469
intraductal papillary-mucinous neoplasm (IPMN) 3,204 | 3,204
malignant mesothelioma 3,135 | 3,135
Astrocytoma, Pilocytic 3,006 | 3,006
primitive neuroectodermal tumor 2,957 | 2,957
intraductal papillary-mucinous carcinoma (IPMC) 2,902 | 2,902
intraductal papillary-mucinous adenoma (IPMA) 2,872 | 2,872
invasive ductal carcinoma 2,867 | 2,867
non-small cell lung cancer 2,799 | 2,799
oligodendroglioma 2,768 | 2,768
lung carcinoma 2,755 | 2,755
lung adenocarcinoma 2,627 | 2,627
Kidney cancer 2,548 | 2,548
astrocytic glioma 2,530 | 2,530
Cancer 2,388 | 2,388
pancreatic cancer 2,322 | 2,322
interstitial cystitis 2,237 | 2,237
subependymal giant cell astrocytoma 2,230 | 2,230
tuberculosis 1,963 | 1,963
pituitary cancer 1,915 | 1,915
pancreatic ductal adenocarcinoma liver metastasis 1,911 | 1,911
Pick disease 1,856 | 1,856
group 4 medulloblastoma 1,806 | 1,806
ulcerative colitis 1,765 | 1,765
ductal carcinoma in situ 1,686 | 1,686
diabetes mellitus 1,683 | 1,683
cystic fibrosis 1,629 | 1,629
breast carcinoma 1,589 | 1,589
colon cancer 1,428 | 1,428
Autosomal recessive predisposition 1,407 | 1,407
adrenocortical carcinoma 1,385 | 1,385
Multiple myeloma 1,296 | 1,296
Rheumatoid arthritis 1,156 | 1,156
juvenile dermatomyositis 1,147 | 1,147
Schizophrenia 1,136 | 1,136
acute quadriplegic myopathy 1,133 | 1,133
astrocytoma 1,113 | 1,113
primary pancreatic ductal adenocarcinoma 1,071 | 1,071
spina bifida 1,053 | 1,053
pediatric high grade glioma 1,035 | 1,035
nasopharyngeal carcinoma 1,024 | 1,024
cutaneous lupus erythematosus 1,016 | 1,016
Intellectual disability 998 | 998
dermatomyositis 941 | 941
Atopic dermatitis 915 | 915
active Crohn's disease 882 | 882
non primary Sjogren syndrome sicca 861 | 861
gastric carcinoma 781 | 781
Epilepsy 775 | 775
acute myeloid leukemia 760 | 760
Waldenstrons macroglobulinemia 742 | 742
active ulcerative colitis 736 | 736
Liver Cirrhosis, Experimental 733 | 733
primary Sjogren syndrome 710 | 710
medulloblastoma 702 | 702
esophageal adenocarcinoma 696 | 696
Melanoma 689 | 689
progressive supranuclear palsy 656 | 656
Obesity 655 | 655
Bipolar Disorder 646 | 646
aldosterone-producing adenoma 646 | 646
Alzheimer's disease 640 | 640
Dull intelligence 634 | 634
Low intelligence 634 | 634
Mental Retardation 634 | 634
Mental deficiency 634 | 634
Poor school performance 634 | 634
Cognitive delay 596 | 596
Global developmental delay 596 | 596
Mental and motor retardation 596 | 596
Liver cancer 589 | 589
Duchenne muscular dystrophy 587 | 587
Seizures 584 | 584
Muscle hypotonia 562 | 562
pancreatic carcinoma 555 | 555
fibroadenoma 538 | 538
hepatocellular carcinoma 536 | 536
Multiple Sclerosis 527 | 527
Endometriosis 521 | 521
Short stature 514 | 514
chronic rhinosinusitis 505 | 505
autosomal dominant Emery-Dreifuss muscular dystrophy 492 | 492
Down syndrome 480 | 480
mucosa-associated lymphoid tissue lymphoma 473 | 473
Prostatic Neoplasms 472 | 472
sonic hedgehog group medulloblastoma 459 | 459
posterior fossa group A ependymoma 456 | 456
Skin cancer 451 | 451
gastric cancer 445 | 445

Tissue

Endocrine System 3,953 | 18,159
Nervous System 3,929 | 16,725
Digestive Tract 3,909 | 17,369
Skin and soft tissues 3,906 | 17,230
Female tissues 3,904 | 17,400
Male tissues 3,890 | 17,142
Liver and Pancreas 3,852 | 16,750
Blood and immune system 3,849 | 16,909
Urinary Tract 3,848 | 16,678
Respiratory system 3,803 | 16,393
Cardiovascular System 3,642 | 15,192

Target Family

Non-IDG 2,341 | 12,091
Enzyme 812 | 4,145
Transcription Factor 320 | 1,400
Kinase 165 | 634
Transporter 94 | 473
Ion Channel 92 | 344
Epigenetic 86 | 242
GPCR 62 | 408
Nuclear Receptor 14 | 48
TF/Epigenetic 13 | 38
oGPCR 3 | 421

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Vascular endothelial zinc finger 1 VEZF1 Tbio Transcription Factor -2.04566 107.4 83
Nidogen-2 NID2 Tbio Non-IDG -1.62355 40.1 116
Protein RCC2 RCC2 Tbio Non-IDG -1.49831 31.4 148
Protocadherin-7 PCDH7 Tbio Non-IDG -1.42056 26.3 248
Docking protein 5 DOK5 Tbio Non-IDG -1.04456 11.4 284
Ryanodine receptor 1 RYR1 Tclin Ion Channel -3.00978 1018.9 103
ATP-dependent DNA helicase DDX11 DDX11 Tbio Enzyme -1.05592 30.0 163
Protein FAM189A1 FAM189A1 Tdark Non-IDG 0.11 0.69 20
Protein atonal homolog 7 ATOH7 Tbio Transcription Factor -3.08645 1060.6 178
Zinc finger protein 423 ZNF423 Tbio Transcription Factor -1.62303 45.3 77