Development Level

Tbio 93 | 11,445
Tdark 26 | 6,588
Tchem 15 | 1,598
Tclin 8 | 613

Collection

RFA-RM-18-021 6 | 328
Ion Channel: IDG Consortium (T... 3 | 99
GPCR: IDG Consortium (Complete... 2 | 25
GPCR: IDG Consortium (Targets) 1 | 126
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 14 | 979
preweaning lethality, incomple... 8 | 499
embryonic lethality prior to t... 7 | 278
decreased vertical activity 6 | 208
enlarged heart 6 | 210
embryonic lethality prior to o... 5 | 239
abnormal behavior 3 | 298
abnormal eye morphology 3 | 68
abnormal heart morphology 3 | 162
abnormal craniofacial morpholo... 2 | 33
abnormal embryo size 2 | 220
abnormal facial morphology 2 | 17
abnormal neural tube closure 2 | 46
abnormal seminal vesicle morph... 2 | 114
cleft palate 2 | 8
decreased circulating bilirubi... 2 | 19
decreased circulating total pr... 2 | 49
decreased grip strength 2 | 116
decreased lean body mass 2 | 135
decreased total body fat amoun... 2 | 207
embryonic growth retardation 2 | 106
increased lean body mass 2 | 172
increased or absent threshold ... 2 | 101
abnormal body wall morphology 1 | 9
abnormal bone structure 1 | 187
abnormal coat- hair morphology 1 | 19
abnormal coat-hair pigmentatio... 1 | 64
abnormal forebrain morphology 1 | 10
abnormal hindbrain morphology 1 | 10
abnormal kidney morphology 1 | 65
abnormal limb bud morphology 1 | 17
abnormal limb morphology 1 | 13
abnormal liver size 1 | 5
abnormal locomotor activation 1 | 16
abnormal lymph node morphology 1 | 3
abnormal midbrain morphology 1 | 10
abnormal pericardium morpholog... 1 | 26
abnormal sleep behavior 1 | 70
abnormal spleen morphology 1 | 55
abnormal tail morphology 1 | 25
abnormal tibia morphology 1 | 14
cataract 1 | 92
cyanosis 1 | 7
decreased body length 1 | 101
decreased body weight 1 | 161
decreased cardiac muscle contr... 1 | 11
decreased circulating HDL chol... 1 | 68
decreased circulating amylase ... 1 | 28
decreased circulating calcium ... 1 | 36
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating serum al... 1 | 82
decreased circulating triglyce... 1 | 79
decreased heart left ventricle... 1 | 28
decreased heart rate 1 | 18
decreased heart weight 1 | 27
decreased hemoglobin content 1 | 68
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular hem... 1 | 31
decreased mean corpuscular vol... 1 | 79
decreased respiratory quotient 1 | 16
decreased startle reflex 1 | 75
decreased threshold for audito... 1 | 26
enlarged lymph nodes 1 | 37
enlarged spleen 1 | 41
hemorrhage 1 | 23
hydrometra 1 | 53
hyperactivity 1 | 148
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
improved glucose tolerance 1 | 79
increased body length 1 | 32
increased bone mineral content 1 | 108
increased circulating alkaline... 1 | 122
increased circulating insulin ... 1 | 3
increased circulating total pr... 1 | 28
increased heart weight 1 | 62
increased large unstained cell... 1 | 5
increased mean corpuscular vol... 1 | 92
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
long tibia 1 | 25
male infertility 1 | 123
polydactyly 1 | 7
prolonged RR interval 1 | 8
short tibia 1 | 97
small adrenal glands 1 | 16
small heart 1 | 10
small lymph nodes 1 | 1
small superior vagus ganglion 1 | 74
small testis 1 | 58
thin ventricular wall 1 | 24
thrombocytopenia 1 | 56

Disease

glioblastoma multiforme 142 | 142
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Endocrine System 140 | 18,159
Nervous System 140 | 16,725
Liver and Pancreas 139 | 16,750
Male tissues 139 | 17,142
Skin and soft tissues 139 | 17,230
Digestive Tract 138 | 17,369
Female tissues 138 | 17,400
Blood and immune system 137 | 16,909
Urinary Tract 136 | 16,678
Respiratory system 135 | 16,393
Cardiovascular System 128 | 15,192

Target Family

Non-IDG 75 | 12,091
Enzyme 35 | 4,145
Transcription Factor 13 | 1,400
GPCR 7 | 408
Kinase 6 | 634
Ion Channel 4 | 344
Epigenetic 1 | 242
Transporter 1 | 473

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Lysosomal Pro-X carboxypeptidase PRCP Tchem Enzyme -1.87633 85.9 165
Synergin gamma SYNRG Tdark Non-IDG -1.69335 48.2 24
A-kinase anchor protein 10, mitochondrial AKAP10 Tbio Enzyme -1.41570 26.7 202
FERM domain-containing protein 8 FRMD8 Tdark Non-IDG 0.48 0.20 104
Putative uncharacterized protein SNHG12 SNHG12 Tdark Non-IDG 0.00000 0
Homeobox protein MSX-1 MSX1 Tbio Transcription Factor -2.59245 390.1 298
Sorcin SRI Tbio Non-IDG -2.69915 481.5 119
Protein CROC-4 C1orf61 Tdark Non-IDG -0.25085 1.87 11
Protein BEX4 BEX4 Tbio Non-IDG -0.42070 1.71 90
Hypoxia-inducible lipid droplet-associated protein HILPDA Tbio Non-IDG -1.24205 21.6 18