Development Level

Tbio 286 | 11,178
Tdark 82 | 6,569
Tchem 57 | 1,885
Tclin 20 | 612

Collection

GPCR: IDG Consortium (Targets) 1 | 126
Ion Channel: IDG Consortium (T... 1 | 99
Kinase: IDG Consortium (Comple... 1 | 37
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 23 | 979
preweaning lethality, incomple... 18 | 499
decreased total body fat amoun... 8 | 207
embryonic lethality prior to t... 8 | 278
decreased body weight 7 | 161
abnormal seminal vesicle morph... 6 | 114
decreased lean body mass 6 | 135
increased lean body mass 6 | 172
decreased circulating triglyce... 5 | 79
embryonic lethality prior to o... 5 | 239
abnormal bone structure 4 | 187
abnormal heart morphology 4 | 162
decreased bone mineral content 4 | 151
decreased hemoglobin content 4 | 68
decreased leukocyte cell numbe... 4 | 73
increased heart weight 4 | 62
increased mean corpuscular vol... 4 | 92
increased total body fat amoun... 4 | 134
male infertility 4 | 123
thrombocytopenia 4 | 56
abnormal behavior 3 | 298
abnormal coat-hair pigmentatio... 3 | 64
abnormal embryo size 3 | 220
abnormal epididymis morphology 3 | 42
cataract 3 | 92
decreased body length 3 | 101
decreased bone mineral density 3 | 126
decreased circulating alanine ... 3 | 47
decreased circulating insulin ... 3 | 76
decreased erythrocyte cell num... 3 | 62
decreased hematocrit 3 | 46
decreased lymphocyte cell numb... 3 | 83
decreased vertical activity 3 | 208
enlarged epididymis 3 | 31
enlarged heart 3 | 210
female infertility 3 | 60
improved glucose tolerance 3 | 79
increased circulating choleste... 3 | 66
increased mean corpuscular hem... 3 | 96
increased neutrophil cell numb... 3 | 46
prenatal lethality prior to he... 3 | 87
small superior vagus ganglion 3 | 74
abnormal cranium morphology 2 | 36
abnormal lens morphology 2 | 81
abnormal retina morphology 2 | 71
abnormal retinal vasculature m... 2 | 27
abnormal skin morphology 2 | 50
abnormal sleep behavior 2 | 70
abnormal spleen morphology 2 | 55
abnormal testis morphology 2 | 43
corneal opacity 2 | 32
decreased circulating LDL chol... 2 | 38
decreased circulating glucose ... 2 | 126
decreased fasted circulating g... 2 | 65
decreased grip strength 2 | 116
decreased heart rate 2 | 18
decreased heart weight 2 | 27
decreased mean corpuscular hem... 2 | 31
decreased spleen weight 2 | 10
decreased startle reflex 2 | 75
embryonic growth retardation 2 | 106
enlarged kidney 2 | 14
enlarged seminal vesicle 2 | 10
enlarged uterus 2 | 11
increased blood urea nitrogen ... 2 | 48
increased body weight 2 | 25
increased circulating HDL chol... 2 | 80
increased circulating alkaline... 2 | 122
increased circulating iron lev... 2 | 30
increased circulating triglyce... 2 | 42
increased fasted circulating g... 2 | 76
increased hematocrit 2 | 46
increased mean corpuscular hem... 2 | 36
increased prepulse inhibition 2 | 32
increased thermal nociceptive ... 2 | 9
irregularly shaped pupil 2 | 7
narrow eye opening 2 | 12
prenatal lethality 2 | 28
small testis 2 | 58
vertebral fusion 2 | 23
abnormal behavioral response t... 1 | 66
abnormal lung morphology 1 | 26
abnormal tooth morphology 1 | 24
abnormal vertebrae morphology 1 | 18
decreased IgG1 level 1 | 8
decreased caudal vertebrae num... 1 | 53
decreased circulating amylase ... 1 | 28
decreased circulating serum al... 1 | 82
decreased red blood cell distr... 1 | 41
decreased total retina thickne... 1 | 17
enlarged spleen 1 | 41
impaired pupillary reflex 1 | 26
increased aggression 1 | 4
increased body length 1 | 32
increased bone mineral density 1 | 72
increased circulating phosphat... 1 | 26
increased eosinophil cell numb... 1 | 11
increased startle reflex 1 | 112
persistence of hyaloid vascula... 1 | 33
thrombocytosis 1 | 27

Disease

gastric cancer 445 | 445
Carcinoma 11,192 | 11,192
ovarian cancer 8,297 | 8,297
osteosarcoma 7,766 | 7,766
psoriasis 6,514 | 6,514
medulloblastoma, large-cell 6,086 | 6,086
glioblastoma 5,635 | 5,635
atypical teratoid / rhabdoid tumor 4,971 | 4,971
lung cancer 4,607 | 4,607
ependymoma 4,559 | 4,559
group 3 medulloblastoma 4,002 | 4,002
adult high grade glioma 3,701 | 3,701
Breast cancer 3,469 | 3,469
intraductal papillary-mucinous neoplasm (IPMN) 3,204 | 3,204
malignant mesothelioma 3,135 | 3,135
Astrocytoma, Pilocytic 3,006 | 3,006
primitive neuroectodermal tumor 2,957 | 2,957
intraductal papillary-mucinous carcinoma (IPMC) 2,902 | 2,902
intraductal papillary-mucinous adenoma (IPMA) 2,872 | 2,872
invasive ductal carcinoma 2,867 | 2,867
non-small cell lung cancer 2,799 | 2,799
oligodendroglioma 2,768 | 2,768
lung carcinoma 2,755 | 2,755
lung adenocarcinoma 2,627 | 2,627
Kidney cancer 2,548 | 2,548
astrocytic glioma 2,530 | 2,530
Cancer 2,388 | 2,388
pancreatic cancer 2,322 | 2,322
interstitial cystitis 2,237 | 2,237
subependymal giant cell astrocytoma 2,230 | 2,230
tuberculosis 1,963 | 1,963
pituitary cancer 1,915 | 1,915
pancreatic ductal adenocarcinoma liver metastasis 1,911 | 1,911
Pick disease 1,856 | 1,856
group 4 medulloblastoma 1,806 | 1,806
ulcerative colitis 1,765 | 1,765
ductal carcinoma in situ 1,686 | 1,686
diabetes mellitus 1,683 | 1,683
cystic fibrosis 1,629 | 1,629
breast carcinoma 1,589 | 1,589
colon cancer 1,428 | 1,428
Autosomal recessive predisposition 1,407 | 1,407
adrenocortical carcinoma 1,385 | 1,385
Multiple myeloma 1,296 | 1,296
Rheumatoid arthritis 1,156 | 1,156
juvenile dermatomyositis 1,147 | 1,147
Schizophrenia 1,136 | 1,136
acute quadriplegic myopathy 1,133 | 1,133
astrocytoma 1,113 | 1,113
primary pancreatic ductal adenocarcinoma 1,071 | 1,071
spina bifida 1,053 | 1,053
pediatric high grade glioma 1,035 | 1,035
nasopharyngeal carcinoma 1,024 | 1,024
cutaneous lupus erythematosus 1,016 | 1,016
Intellectual disability 998 | 998
dermatomyositis 941 | 941
Atopic dermatitis 915 | 915
active Crohn's disease 882 | 882
non primary Sjogren syndrome sicca 861 | 861
gastric carcinoma 781 | 781
Epilepsy 775 | 775
acute myeloid leukemia 760 | 760
Waldenstrons macroglobulinemia 742 | 742
active ulcerative colitis 736 | 736
Liver Cirrhosis, Experimental 733 | 733
primary Sjogren syndrome 710 | 710
medulloblastoma 702 | 702
esophageal adenocarcinoma 696 | 696
Melanoma 689 | 689
progressive supranuclear palsy 656 | 656
Obesity 655 | 655
Bipolar Disorder 646 | 646
aldosterone-producing adenoma 646 | 646
Alzheimer's disease 640 | 640
Dull intelligence 634 | 634
Low intelligence 634 | 634
Mental Retardation 634 | 634
Mental deficiency 634 | 634
Poor school performance 634 | 634
Cognitive delay 596 | 596
Global developmental delay 596 | 596
Mental and motor retardation 596 | 596
Liver cancer 589 | 589
Duchenne muscular dystrophy 587 | 587
Seizures 584 | 584
Muscle hypotonia 562 | 562
pancreatic carcinoma 555 | 555
fibroadenoma 538 | 538
hepatocellular carcinoma 536 | 536
Multiple Sclerosis 527 | 527
Endometriosis 521 | 521
Short stature 514 | 514
chronic rhinosinusitis 505 | 505
autosomal dominant Emery-Dreifuss muscular dystrophy 492 | 492
Down syndrome 480 | 480
mucosa-associated lymphoid tissue lymphoma 473 | 473
Prostatic Neoplasms 472 | 472
sonic hedgehog group medulloblastoma 459 | 459
posterior fossa group A ependymoma 456 | 456
Skin cancer 451 | 451

Tissue

Blood and immune system 440 | 16,909
Skin and soft tissues 440 | 17,230
Digestive Tract 439 | 17,369
Endocrine System 439 | 18,159
Respiratory system 439 | 16,393
Urinary Tract 439 | 16,678
Female tissues 438 | 17,400
Liver and Pancreas 438 | 16,750
Male tissues 437 | 17,142
Nervous System 436 | 16,725
Cardiovascular System 431 | 15,192

Target Family

Non-IDG 251 | 12,091
Enzyme 108 | 4,145
Transcription Factor 38 | 1,400
Kinase 12 | 634
Transporter 12 | 473
Epigenetic 7 | 242
GPCR 7 | 408
Ion Channel 4 | 344
Nuclear Receptor 4 | 48
TF/Epigenetic 2 | 38

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Neutrophil gelatinase-associated lipocalin LCN2 Tbio Enzyme -3.35178 2368.1 847
2-5A-dependent ribonuclease RNASEL Tchem Kinase -2.71673 525.8 127
DNA-directed RNA polymerase I subunit RPA2 POLR1B Tbio Enzyme -0.78946 5.77 86
Zinc finger protein with KRAB and SCAN domains 7 ZKSCAN7 Tbio Transcription Factor -2.02912 100.6 54
Zinc finger protein 320 ZNF320 Tdark Transcription Factor -0.14483 1.30 30
C-type lectin domain family 1 member B CLEC1B Tbio Non-IDG -1.92806 93.6 224
Glucose 1,6-bisphosphate synthase PGM2L1 Tbio Enzyme -0.50191 2.73 91
Rho-related GTP-binding protein RhoU RHOU Tbio Enzyme -1.30084 24.8 95
Centrosomal protein of 104 kDa CEP104 Tbio Non-IDG -1.23064 17.5 69
Intron-binding protein aquarius AQR Tbio Non-IDG -1.58594 38.3 56