Development Level

Tbio 394 | 11,651
Tdark 83 | 6,593
Tchem 48 | 1,388
Tclin 34 | 612

Collection

RFA-RM-18-021 9 | 328
Ion Channel: IDG Consortium (T... 4 | 99
Kinase: IDG Consortium (Target... 3 | 125
GPCR: IDG Consortium (Targets) 2 | 126
Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 22 | 979
abnormal behavior 14 | 298
decreased vertical activity 13 | 208
hyperactivity 11 | 148
preweaning lethality, incomple... 10 | 499
decreased body weight 8 | 161
embryonic lethality prior to t... 8 | 278
hypoactivity 8 | 132
abnormal bone structure 7 | 187
abnormal heart morphology 7 | 162
decreased total body fat amoun... 7 | 207
enlarged heart 7 | 210
abnormal gait 6 | 69
decreased fasted circulating g... 6 | 65
increased lean body mass 6 | 172
increased mean corpuscular vol... 6 | 92
increased total body fat amoun... 6 | 134
abnormal embryo size 5 | 220
abnormal lens morphology 5 | 81
decreased bone mineral density 5 | 126
decreased circulating choleste... 5 | 93
decreased circulating serum al... 5 | 82
decreased circulating triglyce... 5 | 79
decreased grip strength 5 | 116
decreased prepulse inhibition 5 | 82
decreased startle reflex 5 | 75
increased fasted circulating g... 5 | 76
increased neutrophil cell numb... 5 | 46
abnormal sleep behavior 4 | 70
decreased bone mineral content 4 | 151
decreased circulating amylase ... 4 | 28
decreased circulating glucose ... 4 | 126
decreased mean corpuscular vol... 4 | 79
increased bone mineral content 4 | 108
increased heart weight 4 | 62
increased hematocrit 4 | 46
increased or absent threshold ... 4 | 101
small superior vagus ganglion 4 | 74
abnormal behavioral response t... 3 | 66
abnormal coat-hair pigmentatio... 3 | 64
abnormal cranium morphology 3 | 36
abnormal eye morphology 3 | 68
abnormal kidney morphology 3 | 65
abnormal retina morphology 3 | 71
abnormal seminal vesicle morph... 3 | 114
abnormal skin morphology 3 | 50
abnormal spleen morphology 3 | 55
cardiovascular system phenotyp... 3 | 36
decreased CD4-positive, alpha ... 3 | 7
decreased T cell number 3 | 15
decreased circulating insulin ... 3 | 76
decreased circulating total pr... 3 | 49
decreased lymphocyte cell numb... 3 | 83
decreased neutrophil cell numb... 3 | 42
embryonic lethality prior to o... 3 | 239
female infertility 3 | 60
hydrometra 3 | 53
impaired glucose tolerance 3 | 75
improved glucose tolerance 3 | 79
increased circulating HDL chol... 3 | 80
increased circulating choleste... 3 | 66
increased mean corpuscular hem... 3 | 96
increased startle reflex 3 | 112
limb grasping 3 | 41
male infertility 3 | 123
prenatal lethality prior to he... 3 | 87
thrombocytopenia 3 | 56
abnormal bone mineralization 2 | 38
abnormal ear morphology 2 | 9
abnormal head morphology 2 | 10
abnormal limb bud morphology 2 | 17
abnormal neural tube closure 2 | 46
abnormal startle reflex 2 | 15
abnormal whole-body plethysmog... 2 | 4
corneal opacity 2 | 32
decreased IgG1 level 2 | 8
decreased circulating alkaline... 2 | 46
decreased circulating fructosa... 2 | 30
decreased hemoglobin content 2 | 68
decreased red blood cell distr... 2 | 41
edema 2 | 59
enlarged uterus 2 | 11
increased blood urea nitrogen ... 2 | 48
increased blood uric acid leve... 2 | 5
increased circulating alkaline... 2 | 122
increased circulating amylase ... 2 | 25
increased circulating calcium ... 2 | 34
increased circulating creatini... 2 | 38
increased circulating phosphat... 2 | 26
increased circulating serum al... 2 | 22
increased circulating triglyce... 2 | 42
increased hemoglobin content 2 | 45
increased prepulse inhibition 2 | 32
increased red blood cell distr... 2 | 34
microphthalmia 2 | 26
pallor 2 | 34
prolonged QT interval 2 | 38
prolonged ST segment 2 | 36
short tibia 2 | 97
tremors 2 | 39

Disease

fibroadenoma 559 | 559
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Endocrine System 556 | 18,159
Female tissues 556 | 17,400
Digestive Tract 555 | 17,369
Male tissues 555 | 17,142
Skin and soft tissues 555 | 17,230
Blood and immune system 552 | 16,909
Liver and Pancreas 552 | 16,750
Urinary Tract 552 | 16,678
Respiratory system 548 | 16,393
Nervous System 546 | 16,725
Cardiovascular System 528 | 15,192

Target Family

Non-IDG 330 | 12,091
Enzyme 129 | 4,145
Transcription Factor 35 | 1,400
Kinase 25 | 634
GPCR 14 | 408
Transporter 14 | 473
Ion Channel 9 | 344
Nuclear Receptor 3 | 48

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Dual specificity protein phosphatase 1 DUSP1 Tchem Enzyme -2.88260 810.9 388
CMRF35-like molecule 9 CD300LG Tdark Non-IDG -0.92828 10.3 49
Proprotein convertase subtilisin/kexin type 6 PCSK6 Tchem Enzyme -2.33983 216.4 239
4-aminobutyrate aminotransferase, mitochondrial ABAT Tclin Enzyme -2.02391 104.3 204
Butyrophilin-like protein 9 BTNL9 Tdark Non-IDG -0.69979 4.69 67
Macrophage receptor MARCO MARCO Tbio Non-IDG -2.37206 210.3 189
Collagen and calcium-binding EGF domain-containing protein 1 CCBE1 Tbio Non-IDG -1.27652 20.3 165
Transmembrane protein FAM155A FAM155A Tdark Non-IDG 0.19 0.58 69
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform PPP2R1B Tbio Enzyme -1.20793 16.9 203
Procollagen C-endopeptidase enhancer 2 PCOLCE2 Tbio Enzyme -0.74149 6.98 109