Development Level

Tbio 81 | 11,651
Tchem 10 | 1,388
Tdark 7 | 6,593
Tclin 2 | 612

IMPC Phenotype

preweaning lethality, incomple... 6 | 499
preweaning lethality, complete... 4 | 979
cataract 2 | 92
decreased vertical activity 2 | 208
embryonic lethality prior to t... 2 | 278
hypoactivity 2 | 132
impaired glucose tolerance 2 | 75
increased fasted circulating g... 2 | 76
abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal coat appearance 1 | 31
abnormal coat-hair pigmentatio... 1 | 64
abnormal embryo size 1 | 220
abnormal lens morphology 1 | 81
abnormal lip morphology 1 | 2
abnormal locomotor behavior 1 | 24
abnormal retina morphology 1 | 71
abnormal skin coloration 1 | 25
abnormal sleep behavior 1 | 70
abnormal tail morphology 1 | 25
absent testes 1 | 6
aorta stenosis 1 | 2
convulsive seizures 1 | 13
decreased blood urea nitrogen ... 1 | 51
decreased circulating creatini... 1 | 39
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating potassiu... 1 | 20
decreased food intake 1 | 13
decreased grip strength 1 | 116
decreased heart weight 1 | 27
decreased neutrophil cell numb... 1 | 42
decreased red blood cell distr... 1 | 41
decreased thermal nociceptive ... 1 | 2
decreased threshold for audito... 1 | 26
decreased total retina thickne... 1 | 17
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
enlarged liver 1 | 2
enlarged spleen 1 | 41
eye hemorrhage 1 | 1
increased body length 1 | 32
increased body temperature 1 | 9
increased body weight 1 | 25
increased circulating HDL chol... 1 | 80
increased circulating iron lev... 1 | 30
increased circulating triglyce... 1 | 42
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased mean platelet volume 1 | 45
unresponsive to tactile stimul... 1 | 8

Disease

fascioscapulohumeral muscular dystrophy 100 | 100
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Blood and immune system 99 | 16,909
Digestive Tract 99 | 17,369
Endocrine System 99 | 18,159
Female tissues 99 | 17,400
Male tissues 99 | 17,142
Skin and soft tissues 99 | 17,230
Liver and Pancreas 98 | 16,750
Nervous System 98 | 16,725
Respiratory system 98 | 16,393
Urinary Tract 98 | 16,678
Cardiovascular System 95 | 15,192

Target Family

Non-IDG 65 | 12,091
Enzyme 18 | 4,145
Transcription Factor 11 | 1,400
GPCR 2 | 408
Kinase 2 | 634
Epigenetic 1 | 242
Nuclear Receptor 1 | 48

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Procollagen C-endopeptidase enhancer 2 PCOLCE2 Tbio Enzyme -0.74149 6.98 109
Cbp/p300-interacting transactivator 2 CITED2 Tbio Non-IDG -2.07760 134.8 167
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 SAMHD1 Tbio Enzyme -3.96722 8709.0 274
Ubiquitin-conjugating enzyme E2 Q2 UBE2Q2 Tbio Non-IDG -0.88971 8.59 153
Protein prune homolog 2 PRUNE2 Tbio Non-IDG -1.04301 12.3 82
Atypical chemokine receptor 3 ACKR3 Tchem GPCR -1.91187 99.0 476
Collagen alpha-1(III) chain COL3A1 Tbio Non-IDG -2.58251 354.8 439
Transcriptional repressor protein YY1 YY1 Tbio Transcription Factor -2.80737 619.7 475
Aspartyl/asparaginyl beta-hydroxylase ASPH Tbio Enzyme -2.70558 505.4 235
Trinucleotide repeat-containing gene 6A protein TNRC6A Tbio Non-IDG -2.08032 118.3 77