Development Level

Tbio 146 | 11,445
Tdark 106 | 6,588
Tchem 22 | 1,598
Tclin 14 | 613

Collection

RFA-RM-18-021 6 | 328
GPCR: IDG Consortium (Targets) 2 | 126
Ion Channel: IDG Consortium (T... 2 | 99
Kinase: IDG Consortium (Target... 2 | 125

IMPC Phenotype

preweaning lethality, complete... 10 | 979
abnormal embryo size 4 | 220
decreased prepulse inhibition 4 | 82
decreased startle reflex 4 | 75
increased startle reflex 4 | 112
limb grasping 4 | 41
decreased fasted circulating g... 3 | 65
decreased hemoglobin content 3 | 68
decreased total body fat amoun... 3 | 207
embryonic lethality prior to t... 3 | 278
hyperactivity 3 | 148
improved glucose tolerance 3 | 79
increased lean body mass 3 | 172
abnormal behavior 2 | 298
abnormal bone structure 2 | 187
abnormal seminal vesicle morph... 2 | 114
abnormal sleep behavior 2 | 70
absent startle reflex 2 | 24
cyanosis 2 | 7
cystolithiasis 2 | 3
decreased body weight 2 | 161
decreased circulating glucose ... 2 | 126
decreased circulating insulin ... 2 | 76
decreased circulating iron lev... 2 | 32
decreased circulating serum al... 2 | 82
decreased hematocrit 2 | 46
decreased lean body mass 2 | 135
decreased leukocyte cell numbe... 2 | 73
decreased lymphocyte cell numb... 2 | 83
enlarged urinary bladder 2 | 8
impaired pupillary reflex 2 | 26
increased blood urea nitrogen ... 2 | 48
increased body length 2 | 32
increased circulating sodium l... 2 | 71
increased fasted circulating g... 2 | 76
increased heart weight 2 | 62
increased monocyte cell number 2 | 63
increased neutrophil cell numb... 2 | 46
polycystic kidney 2 | 15
preweaning lethality, incomple... 2 | 499
abnormal bone mineralization 1 | 38
abnormal coat appearance 1 | 31
abnormal coat-hair pigmentatio... 1 | 64
abnormal craniofacial morpholo... 1 | 33
abnormal ear morphology 1 | 9
abnormal epididymis morphology 1 | 42
abnormal eye anterior chamber ... 1 | 9
abnormal eye morphology 1 | 68
abnormal forebrain morphology 1 | 10
abnormal gait 1 | 69
abnormal kidney morphology 1 | 65
abnormal locomotor activation 1 | 16
abnormal neural tube closure 1 | 46
abnormal pupil morphology 1 | 2
abnormal spleen morphology 1 | 55
abnormal startle reflex 1 | 15
abnormal tail morphology 1 | 25
abnormal tail movements 1 | 12
abnormal urinary bladder morph... 1 | 11
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased cardiac muscle contr... 1 | 11
decreased circulating amylase ... 1 | 28
decreased circulating bilirubi... 1 | 19
decreased circulating fructosa... 1 | 30
decreased circulating potassiu... 1 | 20
decreased circulating sodium l... 1 | 22
decreased eosinophil cell numb... 1 | 24
decreased erythrocyte cell num... 1 | 62
decreased exploration in new e... 1 | 11
decreased vertical activity 1 | 208
dilated heart left ventricle 1 | 11
embryonic growth retardation 1 | 106
enlarged kidney 1 | 14
enlarged spleen 1 | 41
hemorrhage 1 | 23
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
impaired righting response 1 | 26
increased circulating HDL chol... 1 | 80
increased circulating amylase ... 1 | 25
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating fructosa... 1 | 13
increased circulating serum al... 1 | 22
increased circulating triglyce... 1 | 42
increased leukocyte cell numbe... 1 | 47
increased mean platelet volume 1 | 45
increased or absent threshold ... 1 | 101
increased red blood cell distr... 1 | 34
increased spleen weight 1 | 10
increased total body fat amoun... 1 | 134
male infertility 1 | 123
mammalian phenotype 1 | 17
prenatal lethality prior to he... 1 | 87
small kidney 1 | 16
tremors 1 | 39

Disease

facioscapulohumeral dystrophy 288 | 288
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Endocrine System 257 | 18,159
Female tissues 232 | 17,400
Skin and soft tissues 230 | 17,230
Digestive Tract 229 | 17,369
Nervous System 225 | 16,725
Male tissues 222 | 17,142
Blood and immune system 215 | 16,909
Urinary Tract 215 | 16,678
Liver and Pancreas 211 | 16,750
Respiratory system 204 | 16,393
Cardiovascular System 171 | 15,192

Target Family

Non-IDG 164 | 12,091
Enzyme 50 | 4,145
Transcription Factor 34 | 1,400
Transporter 14 | 473
Kinase 10 | 634
GPCR 7 | 408
Ion Channel 5 | 344
Epigenetic 2 | 242
TF/Epigenetic 2 | 38

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
MAGE-like protein 2 MAGEL2 Tbio Non-IDG -1.95242 83.8 86
Redox-regulatory protein FAM213A FAM213A Tbio Non-IDG -1.51277 30.6 63
Neuromodulin GAP43 Tbio Non-IDG -2.93905 762.9 597
Putative methyl-CpG-binding domain protein 3-like 3 MBD3L3 Tdark Non-IDG 0.00000 56
NACHT, LRR and PYD domains-containing protein 2 NLRP2 Tbio Non-IDG -1.82146 68.5 245
Putative upstream-binding factor 1-like protein 6 UBTFL6 Tdark Non-IDG 0.00000 0
Upstream-binding factor 1-like protein 1 UBTFL1 Tdark Transcription Factor 0.00000 17
Nicotinamide N-methyltransferase NNMT Tchem Enzyme -2.09313 121.9 268
Homeobox protein Hox-D9 HOXD9 Tbio Transcription Factor -1.52954 36.2 137
Roundabout homolog 2 ROBO2 Tbio Non-IDG -1.89275 74.1 161