Development Level

Tbio 741 | 11,651
Tchem 117 | 1,388
Tdark 78 | 6,593
Tclin 30 | 612

Collection

Kinase: IDG Consortium (Target... 5 | 125
Kinase: IDG Consortium (Comple... 4 | 37
GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

preweaning lethality, complete... 86 | 979
preweaning lethality, incomple... 32 | 499
embryonic lethality prior to t... 25 | 278
abnormal behavior 21 | 298
embryonic lethality prior to o... 21 | 239
abnormal embryo size 20 | 220
decreased body weight 14 | 161
decreased total body fat amoun... 13 | 207
decreased bone mineral density 11 | 126
decreased vertical activity 11 | 208
hypoactivity 11 | 132
increased startle reflex 11 | 112
increased lean body mass 10 | 172
abnormal bone structure 9 | 187
decreased body length 9 | 101
decreased lean body mass 9 | 135
embryonic growth retardation 9 | 106
decreased circulating choleste... 8 | 93
increased bone mineral content 8 | 108
increased fasted circulating g... 8 | 76
abnormal retina morphology 7 | 71
decreased bone mineral content 7 | 151
decreased mean corpuscular vol... 7 | 79
decreased prepulse inhibition 7 | 82
increased blood urea nitrogen ... 7 | 48
increased bone mineral density 7 | 72
increased circulating choleste... 7 | 66
increased mean corpuscular vol... 7 | 92
short tibia 7 | 97
abnormal gait 6 | 69
decreased grip strength 6 | 116
edema 6 | 59
hyperactivity 6 | 148
increased circulating HDL chol... 6 | 80
increased mean corpuscular hem... 6 | 96
increased or absent threshold ... 6 | 101
increased total body fat amoun... 6 | 134
prenatal lethality prior to he... 6 | 87
abnormal lens morphology 5 | 81
anophthalmia 5 | 33
cataract 5 | 92
decreased circulating glucose ... 5 | 126
decreased leukocyte cell numbe... 5 | 73
decreased mean corpuscular hem... 5 | 50
decreased neutrophil cell numb... 5 | 42
increased circulating alkaline... 5 | 122
increased heart weight 5 | 62
increased hematocrit 5 | 46
increased lymphocyte cell numb... 5 | 32
male infertility 5 | 123
thrombocytopenia 5 | 56
abnormal coat-hair pigmentatio... 4 | 64
abnormal craniofacial morpholo... 4 | 33
abnormal neural tube closure 4 | 46
decreased blood urea nitrogen ... 4 | 51
decreased caudal vertebrae num... 4 | 53
decreased circulating triglyce... 4 | 79
decreased erythrocyte cell num... 4 | 62
decreased hemoglobin content 4 | 68
decreased lymphocyte cell numb... 4 | 83
decreased mean corpuscular hem... 4 | 31
impaired glucose tolerance 4 | 75
increased circulating iron lev... 4 | 30
increased circulating sodium l... 4 | 71
increased erythrocyte cell num... 4 | 39
increased leukocyte cell numbe... 4 | 47
increased neutrophil cell numb... 4 | 46
abnormal behavioral response t... 3 | 66
abnormal bone mineralization 3 | 38
abnormal cranium morphology 3 | 36
abnormal eye morphology 3 | 68
abnormal sleep behavior 3 | 70
absent startle reflex 3 | 24
decreased circulating HDL chol... 3 | 68
decreased circulating amylase ... 3 | 28
decreased circulating insulin ... 3 | 76
decreased circulating iron lev... 3 | 32
decreased circulating total pr... 3 | 49
decreased hematocrit 3 | 46
decreased startle reflex 3 | 75
enlarged heart 3 | 210
enlarged lymph nodes 3 | 37
female infertility 3 | 60
increased circulating glycerol... 3 | 9
increased circulating phosphat... 3 | 26
increased hemoglobin content 3 | 45
increased mean corpuscular hem... 3 | 36
increased red blood cell distr... 3 | 34
microphthalmia 3 | 26
pallor 3 | 34
small testis 3 | 58
abnormal placenta size 2 | 20
abnormal skin coloration 2 | 25
abnormal skin condition 2 | 6
abnormal vibrissa morphology 2 | 25
cardiovascular system phenotyp... 2 | 36
decreased circulating creatini... 2 | 39
decreased fasted circulating g... 2 | 65
increased circulating calcium ... 2 | 34
increased monocyte cell number 2 | 63

Disease

dermatomyositis 966 | 966
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Endocrine System 924 | 18,159
Liver and Pancreas 924 | 16,750
Male tissues 924 | 17,142
Skin and soft tissues 924 | 17,230
Urinary Tract 924 | 16,678
Digestive Tract 923 | 17,369
Female tissues 923 | 17,400
Blood and immune system 921 | 16,909
Respiratory system 921 | 16,393
Cardiovascular System 920 | 15,192
Nervous System 918 | 16,725

Target Family

Non-IDG 608 | 12,091
Enzyme 208 | 4,145
Transcription Factor 46 | 1,400
Kinase 41 | 634
Epigenetic 28 | 242
Transporter 18 | 473
GPCR 7 | 408
Nuclear Receptor 4 | 48
TF/Epigenetic 4 | 38
Ion Channel 2 | 344

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
F-box/WD repeat-containing protein 2 FBXW2 Tbio Non-IDG -2.09381 115.1 104
Ras-related protein Rab-21 RAB21 Tbio Enzyme -1.33715 23.1 275
T-complex protein 1 subunit zeta CCT6A Tbio Non-IDG -1.39880 26.2 90
ATP-binding cassette sub-family A member 1 ABCA1 Tclin Transporter -3.15111 1451.8 388
Cytoplasmic FMR1-interacting protein 1 CYFIP1 Tbio Non-IDG -1.46134 28.5 64
Eukaryotic translation initiation factor 4E transporter EIF4ENIF1 Tbio Non-IDG -1.60874 36.7 242
HLA class I histocompatibility antigen, B-51 alpha chain HLA-B Tbio Non-IDG -1.88752 1613.5 0
Chromobox protein homolog 3 CBX3 Tbio Epigenetic -2.00023 90.5 366
E3 ubiquitin-protein ligase CBL-B CBLB Tbio Enzyme -0.82313 6.58 193
TSC22 domain family protein 1 TSC22D1 Tbio Transcription Factor -1.54599 46.0 300