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Development Level

Tbio 147 | 11,445
Tdark 39 | 6,588
Tchem 20 | 1,598
Tclin 8 | 613

Collection

RFA-RM-18-021 6 | 328
Ion Channel: IDG Consortium (T... 3 | 99
Kinase: IDG Consortium (Target... 3 | 125
Kinase: IDG Consortium (Comple... 2 | 37

IMPC Phenotype

decreased total body fat amoun... 7 | 207
preweaning lethality, complete... 7 | 979
preweaning lethality, incomple... 6 | 499
abnormal embryo size 4 | 220
embryonic lethality prior to t... 4 | 278
enlarged heart 4 | 210
increased bone mineral content 4 | 108
abnormal heart morphology 3 | 162
decreased prepulse inhibition 3 | 82
hydrometra 3 | 53
hypoactivity 3 | 132
increased or absent threshold ... 3 | 101
small superior vagus ganglion 3 | 74
abnormal behavior 2 | 298
abnormal bone structure 2 | 187
abnormal locomotor behavior 2 | 24
abnormal pericardium morpholog... 2 | 26
abnormal retina morphology 2 | 71
abnormal seminal vesicle morph... 2 | 114
abnormal sleep behavior 2 | 70
decreased body weight 2 | 161
decreased bone mineral density 2 | 126
decreased circulating glucose ... 2 | 126
decreased lymphocyte cell numb... 2 | 83
decreased startle reflex 2 | 75
edema 2 | 59
embryonic growth retardation 2 | 106
embryonic lethality prior to o... 2 | 239
hyperactivity 2 | 148
increased bone mineral density 2 | 72
increased circulating HDL chol... 2 | 80
increased heart weight 2 | 62
increased lean body mass 2 | 172
increased mean corpuscular hem... 2 | 96
increased mean corpuscular vol... 2 | 92
increased startle reflex 2 | 112
male infertility 2 | 123
short tibia 2 | 97
thrombocytopenia 2 | 56
tremors 2 | 39
abnormal behavioral response t... 1 | 66
abnormal bone mineralization 1 | 38
abnormal coat-hair pigmentatio... 1 | 64
abnormal cranium morphology 1 | 36
abnormal epididymis morphology 1 | 42
abnormal eye morphology 1 | 68
abnormal gait 1 | 69
abnormal gallbladder morpholog... 1 | 1
abnormal head morphology 1 | 10
abnormal lung morphology 1 | 26
abnormal optic disc morphology 1 | 10
abnormal response to tactile s... 1 | 17
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal snout morphology 1 | 23
abnormal startle reflex 1 | 15
abnormal testis morphology 1 | 43
abnormal urinary bladder morph... 1 | 11
convulsive seizures 1 | 13
corneal opacity 1 | 32
decreased circulating HDL chol... 1 | 68
decreased circulating choleste... 1 | 93
decreased circulating insulin ... 1 | 76
decreased circulating sodium l... 1 | 22
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased heart left ventricle... 1 | 28
decreased heart rate 1 | 18
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular hem... 1 | 31
decreased mean corpuscular vol... 1 | 79
decreased vertical activity 1 | 208
enlarged epididymis 1 | 31
enlarged gallbladder 1 | 2
enlarged seminal vesicle 1 | 10
female infertility 1 | 60
hydroencephaly 1 | 14
impaired glucose tolerance 1 | 75
improved glucose tolerance 1 | 79
increased T cell number 1 | 6
increased body length 1 | 32
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased circulating triglyce... 1 | 42
increased erythrocyte cell num... 1 | 39
increased fasted circulating g... 1 | 76
increased grip strength 1 | 41
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
increased prepulse inhibition 1 | 32
increased total body fat amoun... 1 | 134
limb grasping 1 | 41
prenatal lethality prior to he... 1 | 87
prolonged QT interval 1 | 38
prolonged RR interval 1 | 8
prolonged ST segment 1 | 36
small testis 1 | 58
thin ventricular wall 1 | 24

Disease

cystic fibrosis and chronic rhinosinusitis 214 | 214
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Endocrine System 208 | 18,159
Female tissues 207 | 17,400
Male tissues 207 | 17,142
Digestive Tract 205 | 17,369
Urinary Tract 205 | 16,678
Liver and Pancreas 204 | 16,750
Respiratory system 204 | 16,393
Skin and soft tissues 204 | 17,230
Blood and immune system 203 | 16,909
Nervous System 202 | 16,725
Cardiovascular System 185 | 15,192

Target Family

Non-IDG 142 | 12,091
Enzyme 31 | 4,145
Transcription Factor 17 | 1,400
Kinase 9 | 634
Ion Channel 6 | 344
Transporter 6 | 473
GPCR 2 | 408
Epigenetic 1 | 242

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
B-cell antigen receptor complex-associated protein alpha chain CD79A Tbio Non-IDG -4.45149 28259.4 1170
Serotransferrin TF Tbio Non-IDG -4.15070 13447.9 1168
Receptor tyrosine-protein kinase erbB-4 ERBB4 Tclin Kinase -2.78704 558.2 1072
Heat shock protein HSP 90-alpha HSP90AA1 Tchem Non-IDG -3.31859 4681.5 1057
Cell surface glycoprotein MUC18 MCAM Tbio Non-IDG -2.76771 602.1 1056
Forkhead box protein O3 FOXO3 Tbio Transcription Factor -2.94477 863.9 864
DNA topoisomerase 2-alpha TOP2A Tclin Enzyme -2.88264 723.0 847
Neutrophil gelatinase-associated lipocalin LCN2 Tbio Enzyme -3.35178 2368.1 847
Nitric oxide synthase, inducible NOS2 Tchem Enzyme -3.35134 2277.5 752
Thymidylate synthase TYMS Tclin Enzyme -2.93426 732.0 733