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Target Filters...

Development Level

Tbio 137 | 10,625
Tdark 42 | 7,003
Tchem 23 | 1,890
Tclin 11 | 602

Collection

Eligible Kinase Proteins 3 | 134
Eligible Ion Channel Proteins 1 | 117

IMPC Term

increased mean corpuscular hem... 4 | 93
preweaning lethality, complete... 4 | 633
preweaning lethality, incomple... 4 | 260
thrombocytopenia 3 | 46
abnormal embryo size 2 | 112
abnormal sleep behavior 2 | 63
decreased bone mineral density 2 | 126
embryonic lethality prior to o... 2 | 148
embryonic lethality prior to t... 2 | 187
enlarged heart 2 | 111
hypoactivity 2 | 89
increased circulating serum al... 2 | 25
short tibia 2 | 82
tremors 2 | 34
abnormal QRS complex 1 | 25
abnormal behavioral response t... 1 | 52
abnormal bone mineralization 1 | 55
abnormal bone structure 1 | 131
abnormal cervical vertebrae mo... 1 | 4
abnormal coat/hair pigmentatio... 1 | 54
abnormal cranium morphology 1 | 32
abnormal forebrain development 1 | 18
abnormal head morphology 1 | 10
abnormal hindbrain development 1 | 24
abnormal lung morphology 1 | 15
abnormal midbrain development 1 | 22
abnormal neural tube closure 1 | 37
abnormal pericardium morpholog... 1 | 11
abnormal posture 1 | 5
abnormal response to tactile s... 1 | 16
abnormal retina morphology 1 | 100
abnormal retinal pigmentation 1 | 61
abnormal rib morphology 1 | 28
abnormal snout morphology 1 | 18
abnormal startle reflex 1 | 14
abnormal testis morphology 1 | 30
abnormal urinary bladder morph... 1 | 2
absent startle reflex 1 | 15
cardiovascular system phenotyp... 1 | 35
convulsive seizures 1 | 11
decreased CD8-positive, alpha-... 1 | 26
decreased body weight 1 | 174
decreased caudal vertebrae num... 1 | 49
decreased cervical vertebrae n... 1 | 12
decreased circulating HDL chol... 1 | 77
decreased circulating chloride... 1 | 32
decreased circulating glucose ... 1 | 121
decreased circulating glycerol... 1 | 19
decreased circulating insulin ... 1 | 75
decreased erythrocyte cell num... 1 | 43
decreased fasted circulating g... 1 | 49
decreased heart rate 1 | 10
decreased lean body mass 1 | 195
decreased mean platelet volume 1 | 12
decreased monocyte cell number 1 | 28
decreased prepulse inhibition 1 | 52
decreased startle reflex 1 | 48
decreased threshold for audito... 1 | 32
decreased total body fat amoun... 1 | 186
enlarged epididymis 1 | 27
female infertility 1 | 34
hydroencephaly 1 | 6
increased KLRG1+ CD8 alpha bet... 1 | 2
increased T cell number 1 | 15
increased body length 1 | 20
increased bone mineral content 1 | 92
increased circulating HDL chol... 1 | 63
increased circulating calcium ... 1 | 32
increased circulating chloride... 1 | 43
increased circulating choleste... 1 | 53
increased circulating sodium l... 1 | 71
increased circulating total pr... 1 | 20
increased circulating triglyce... 1 | 24
increased fasted circulating g... 1 | 68
increased grip strength 1 | 83
increased mean corpuscular vol... 1 | 91
increased or absent threshold ... 1 | 128
increased prepulse inhibition 1 | 21
increased respiratory quotient 1 | 12
increased sacral vertebrae num... 1 | 62
increased total body fat amoun... 1 | 57
male infertility 1 | 62
prolonged QRS complex duration 1 | 2
prolonged RR interval 1 | 2
small superior vagus ganglion 1 | 20
small testis 1 | 37
trunk curl 1 | 15

Disease

cystic fibrosis and chronic rhinosinusitis 213 | 213
ovarian cancer 8,492 | 8,492
osteosarcoma 7,933 | 7,933
psoriasis 6,685 | 6,685
medulloblastoma, large-cell 6,234 | 6,234
glioblastoma 5,572 | 5,572
lung cancer 4,473 | 4,473
atypical teratoid / rhabdoid tumor 4,369 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 3,289 | 3,289
malignant mesothelioma 3,163 | 3,163
Breast cancer 3,099 | 3,099
pilocytic astrocytoma 3,086 | 3,086
primitive neuroectodermal tumor 3,031 | 3,031
intraductal papillary-mucinous carcinoma (IPMC) 2,988 | 2,988
intraductal papillary-mucinous adenoma (IPMA) 2,956 | 2,956
invasive ductal carcinoma 2,950 | 2,950
oligodendroglioma 2,849 | 2,849
lung carcinoma 2,844 | 2,844
non-small cell lung cancer 2,798 | 2,798
lung adenocarcinoma 2,714 | 2,714
pediatric high grade glioma 2,712 | 2,712
ependymoma 2,514 | 2,514
Cancer 2,346 | 2,346
pancreatic cancer 2,300 | 2,300
interstitial cystitis 2,299 | 2,299
subependymal giant cell astrocytoma 2,287 | 2,287
group 3 medulloblastoma 2,254 | 2,254
astrocytic glioma 2,241 | 2,241
adult high grade glioma 2,148 | 2,148
Carcinoma 2,147 | 2,147
ulcerative colitis 2,087 | 2,087
pituitary cancer 1,972 | 1,972
Pick disease 1,893 | 1,893
group 4 medulloblastoma 1,875 | 1,875
pancreatic ductal adenocarcinoma liver metastasis 1,795 | 1,795
ductal carcinoma in situ 1,745 | 1,745
cystic fibrosis 1,670 | 1,670
diabetes mellitus 1,663 | 1,663
breast carcinoma 1,614 | 1,614
tuberculosis 1,563 | 1,563
posterior fossa group B ependymoma 1,530 | 1,530
medulloblastoma 1,524 | 1,524
posterior fossa group A ependymoma 1,511 | 1,511
astrocytoma 1,493 | 1,493
sonic hedgehog group medulloblastoma 1,482 | 1,482
colon cancer 1,475 | 1,475
adrenocortical carcinoma 1,427 | 1,427
Multiple myeloma 1,328 | 1,328
primary pancreatic ductal adenocarcinoma 1,271 | 1,271
juvenile dermatomyositis 1,189 | 1,189
Rheumatoid Arthritis 1,171 | 1,171
acute quadriplegic myopathy 1,157 | 1,157
atypical teratoid/rhabdoid tumor 1,095 | 1,095
spina bifida 1,064 | 1,064
cutaneous lupus erythematosus 1,056 | 1,056
nasopharyngeal carcinoma 1,056 | 1,056
dermatomyositis 967 | 967
Atopic dermatitis 944 | 944
active Crohn's disease 918 | 918
non primary Sjogren syndrome sicca 840 | 840
gastric carcinoma 832 | 832
primary Sjogren syndrome 789 | 789
acute myeloid leukemia 785 | 785
Waldenstrons macroglobulinemia 765 | 765
esophageal adenocarcinoma 737 | 737
tuberculosis and treatment for 6 months 686 | 686
progressive supranuclear palsy 674 | 674
aldosterone-producing adenoma 664 | 664
Alzheimer's disease 644 | 644
Obesity 616 | 616
Duchenne muscular dystrophy 602 | 602
Intellectual disability 573 | 573
pancreatic carcinoma 567 | 567
fibroadenoma 557 | 557
hepatocellular carcinoma 550 | 550
Down syndrome 548 | 548
Endometriosis 535 | 535
chronic rhinosinusitis 512 | 512
Schizophrenia 503 | 503
autosomal dominant Emery-Dreifuss muscular dystrophy 499 | 499
Multiple Sclerosis 498 | 498
mucosa-associated lymphoid tissue lymphoma 480 | 480
active ulcerative colitis 477 | 477
Prostatic Neoplasms 471 | 471
IGA Glomerulonephritis 454 | 454
gastric cancer 436 | 436
Amyotrophic Lateral Sclerosis 432 | 432
non-small cell lung carcinoma 413 | 413
Mammary Neoplasms 410 | 410
inflammatory breast cancer 404 | 404
Kidney disease 397 | 397
Neurodegenerative disease 383 | 383
sarcoidosis 368 | 368
Parkinson's disease 364 | 364
Asthma 349 | 349
glioblastoma multiforme 347 | 347
Epilepsy 346 | 346
Polycystic Ovary Syndrome 335 | 335
nephrosclerosis 329 | 329
tuberculosis and treatment for 3 months 327 | 327
Autistic Disorder 320 | 320

Tissue

Cardiovascular System 212 | 17,958
Digestive Tract 212 | 18,473
Endocrine System 212 | 18,512
Female tissues 212 | 18,647
Nervous System 212 | 18,561
Urinary Tract 212 | 18,444
Blood and immune system 211 | 17,995
Liver and Pancreas 211 | 18,136
Male tissues 211 | 17,969
Respiratory system 211 | 17,484
Skin and soft tissues 211 | 18,115

Target Family

Non-IDG 140 | 11,969
Enzyme 32 | 4,146
Transcription Factor 16 | 1,400
Kinase 10 | 634
Transporter 7 | 473
Ion Channel 4 | 341
GPCR 3 | 408
Epigenetic 1 | 242

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Serotransferrin TF Tchem Non-IDG -4.13936 13124.3 952
B-cell antigen receptor complex-associated protein alpha chain CD79A Tbio Non-IDG -4.43926 27478.2 943
Heat shock protein HSP 90-alpha HSP90AA1 Tchem Non-IDG -3.28941 4395.5 921
Receptor tyrosine-protein kinase erbB-4 ERBB4 Tclin Kinase -2.75974 526.1 834
Lactotransferrin LTF Tbio Non-IDG -2.52826 332.5 794
Forkhead box protein O3 FOXO3 Tbio Transcription Factor -2.88928 758.9 787
Neutrophil gelatinase-associated lipocalin LCN2 Tbio Enzyme -3.30350 2128.8 665
Nitric oxide synthase, inducible NOS2 Tchem Enzyme -3.34028 2206.3 649