Development Level

Tbio 137 | 10,625
Tdark 42 | 7,003
Tchem 23 | 1,890
Tclin 11 | 602

Collection

Eligible Kinase Proteins 3 | 134
Eligible Ion Channel Proteins 1 | 117

IMPC Term

increased mean corpuscular hem... 4 | 93
preweaning lethality, complete... 4 | 633
preweaning lethality, incomple... 4 | 260
thrombocytopenia 3 | 46
abnormal embryo size 2 | 112
abnormal sleep behavior 2 | 63
decreased bone mineral density 2 | 126
embryonic lethality prior to o... 2 | 148
embryonic lethality prior to t... 2 | 187
enlarged heart 2 | 111
hypoactivity 2 | 89
increased circulating serum al... 2 | 25
short tibia 2 | 82
tremors 2 | 34
abnormal QRS complex 1 | 25
abnormal behavioral response t... 1 | 52
abnormal bone mineralization 1 | 55
abnormal bone structure 1 | 131
abnormal cervical vertebrae mo... 1 | 4
abnormal coat/hair pigmentatio... 1 | 54
abnormal cranium morphology 1 | 32
abnormal forebrain development 1 | 18
abnormal head morphology 1 | 10
abnormal hindbrain development 1 | 24
abnormal lung morphology 1 | 15
abnormal midbrain development 1 | 22
abnormal neural tube closure 1 | 37
abnormal pericardium morpholog... 1 | 11
abnormal posture 1 | 5
abnormal response to tactile s... 1 | 16
abnormal retina morphology 1 | 100
abnormal retinal pigmentation 1 | 61
abnormal rib morphology 1 | 28
abnormal snout morphology 1 | 18
abnormal startle reflex 1 | 14
abnormal testis morphology 1 | 30
abnormal urinary bladder morph... 1 | 2
absent startle reflex 1 | 15
cardiovascular system phenotyp... 1 | 35
convulsive seizures 1 | 11
decreased CD8-positive, alpha-... 1 | 26
decreased body weight 1 | 174
decreased caudal vertebrae num... 1 | 49
decreased cervical vertebrae n... 1 | 12
decreased circulating HDL chol... 1 | 77
decreased circulating chloride... 1 | 32
decreased circulating glucose ... 1 | 121
decreased circulating glycerol... 1 | 19
decreased circulating insulin ... 1 | 75
decreased erythrocyte cell num... 1 | 43
decreased fasted circulating g... 1 | 49
decreased heart rate 1 | 10
decreased lean body mass 1 | 195
decreased mean platelet volume 1 | 12
decreased monocyte cell number 1 | 28
decreased prepulse inhibition 1 | 52
decreased startle reflex 1 | 48
decreased threshold for audito... 1 | 32
decreased total body fat amoun... 1 | 186
enlarged epididymis 1 | 27
female infertility 1 | 34
hydroencephaly 1 | 6
increased KLRG1+ CD8 alpha bet... 1 | 2
increased T cell number 1 | 15
increased body length 1 | 20
increased bone mineral content 1 | 92
increased circulating HDL chol... 1 | 63
increased circulating calcium ... 1 | 32
increased circulating chloride... 1 | 43
increased circulating choleste... 1 | 53
increased circulating sodium l... 1 | 71
increased circulating total pr... 1 | 20
increased circulating triglyce... 1 | 24
increased fasted circulating g... 1 | 68
increased grip strength 1 | 83
increased mean corpuscular vol... 1 | 91
increased or absent threshold ... 1 | 128
increased prepulse inhibition 1 | 21
increased respiratory quotient 1 | 12
increased sacral vertebrae num... 1 | 62
increased total body fat amoun... 1 | 57
male infertility 1 | 62
prolonged QRS complex duration 1 | 2
prolonged RR interval 1 | 2
small superior vagus ganglion 1 | 20
small testis 1 | 37
trunk curl 1 | 15

Disease

cystic fibrosis and chronic rhinosinusitis 213 | 213
ovarian cancer 8,484 | 8,484
osteosarcoma 7,933 | 7,933
psoriasis 6,685 | 6,685
medulloblastoma, large-cell 6,234 | 6,234
glioblastoma 5,572 | 5,572
lung cancer 4,466 | 4,466
atypical teratoid / rhabdoid tumor 4,369 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 3,289 | 3,289
malignant mesothelioma 3,162 | 3,162
Breast cancer 3,094 | 3,094
pilocytic astrocytoma 3,086 | 3,086
primitive neuroectodermal tumor 3,031 | 3,031
intraductal papillary-mucinous carcinoma (IPMC) 2,988 | 2,988
intraductal papillary-mucinous adenoma (IPMA) 2,956 | 2,956
invasive ductal carcinoma 2,950 | 2,950
oligodendroglioma 2,849 | 2,849
lung carcinoma 2,844 | 2,844
non-small cell lung cancer 2,798 | 2,798
lung adenocarcinoma 2,713 | 2,713
pediatric high grade glioma 2,712 | 2,712
ependymoma 2,514 | 2,514
Cancer 2,346 | 2,346
pancreatic cancer 2,300 | 2,300
interstitial cystitis 2,299 | 2,299
subependymal giant cell astrocytoma 2,287 | 2,287
group 3 medulloblastoma 2,254 | 2,254
astrocytic glioma 2,241 | 2,241
adult high grade glioma 2,148 | 2,148
Carcinoma 2,147 | 2,147
ulcerative colitis 2,087 | 2,087
pituitary cancer 1,972 | 1,972
Pick disease 1,893 | 1,893
group 4 medulloblastoma 1,875 | 1,875
pancreatic ductal adenocarcinoma liver metastasis 1,795 | 1,795
ductal carcinoma in situ 1,745 | 1,745
cystic fibrosis 1,665 | 1,665
diabetes mellitus 1,663 | 1,663
breast carcinoma 1,614 | 1,614
tuberculosis 1,557 | 1,557
posterior fossa group B ependymoma 1,530 | 1,530
medulloblastoma 1,524 | 1,524
posterior fossa group A ependymoma 1,511 | 1,511
astrocytoma 1,493 | 1,493
sonic hedgehog group medulloblastoma 1,482 | 1,482
colon cancer 1,475 | 1,475
adrenocortical carcinoma 1,427 | 1,427
Multiple myeloma 1,327 | 1,327
primary pancreatic ductal adenocarcinoma 1,271 | 1,271
juvenile dermatomyositis 1,189 | 1,189
Rheumatoid Arthritis 1,160 | 1,160
acute quadriplegic myopathy 1,157 | 1,157
atypical teratoid/rhabdoid tumor 1,095 | 1,095
spina bifida 1,064 | 1,064
cutaneous lupus erythematosus 1,056 | 1,056
nasopharyngeal carcinoma 1,056 | 1,056
Atopic dermatitis 944 | 944
dermatomyositis 933 | 933
active Crohn's disease 918 | 918
non primary Sjogren syndrome sicca 840 | 840
gastric carcinoma 832 | 832
primary Sjogren syndrome 789 | 789
acute myeloid leukemia 780 | 780
Waldenstrons macroglobulinemia 765 | 765
esophageal adenocarcinoma 737 | 737
tuberculosis and treatment for 6 months 686 | 686
progressive supranuclear palsy 674 | 674
aldosterone-producing adenoma 664 | 664
Alzheimer's disease 644 | 644
Obesity 616 | 616
Duchenne muscular dystrophy 602 | 602
Intellectual disability 573 | 573
pancreatic carcinoma 567 | 567
fibroadenoma 557 | 557
Down syndrome 548 | 548
Endometriosis 535 | 535
hepatocellular carcinoma 532 | 532
chronic rhinosinusitis 512 | 512
Schizophrenia 501 | 501
autosomal dominant Emery-Dreifuss muscular dystrophy 499 | 499
Multiple Sclerosis 498 | 498
mucosa-associated lymphoid tissue lymphoma 480 | 480
active ulcerative colitis 477 | 477
Prostatic Neoplasms 471 | 471
IGA Glomerulonephritis 454 | 454
Amyotrophic Lateral Sclerosis 431 | 431
gastric cancer 430 | 430
non-small cell lung carcinoma 413 | 413
Mammary Neoplasms 410 | 410
inflammatory breast cancer 404 | 404
Kidney disease 396 | 396
Neurodegenerative disease 383 | 383
Parkinson's disease 364 | 364
sarcoidosis 358 | 358
Asthma 349 | 349
glioblastoma multiforme 347 | 347
Epilepsy 346 | 346
Polycystic Ovary Syndrome 332 | 332
nephrosclerosis 329 | 329
tuberculosis and treatment for 3 months 327 | 327
Autistic Disorder 320 | 320

Tissue

Cardiovascular System 212 | 17,958
Digestive Tract 212 | 18,473
Endocrine System 212 | 18,512
Female tissues 212 | 18,647
Nervous System 212 | 18,561
Urinary Tract 212 | 18,444
Blood and immune system 211 | 17,995
Liver and Pancreas 211 | 18,136
Male tissues 211 | 17,969
Respiratory system 211 | 17,484
Skin and soft tissues 211 | 18,115

Target Family

Non-IDG 140 | 11,971
Enzyme 32 | 4,146
Transcription Factor 16 | 1,400
Kinase 10 | 634
Transporter 7 | 473
Ion Channel 4 | 341
GPCR 3 | 406
Epigenetic 1 | 242

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Nuclear pore complex protein Nup98-Nup96 NUP98 Tbio Enzyme -2.21148 186.3 172
Bardet-Biedl syndrome 7 protein BBS7 Tbio Non-IDG -1.02867 11.1 125
Homeodomain-interacting protein kinase 1 HIPK1 Tbio Kinase -0.62325 4.93 166
Krueppel-like factor 9 KLF9 Tbio Transcription Factor -1.87911 88.8 139
Cytochrome b5 CYB5A Tchem Non-IDG -3.24788 1711.2 249
Lipoma-preferred partner LPP Tbio Non-IDG -2.68601 520.6 153
Serotransferrin TF Tchem Non-IDG -4.13136 13124.3 952
Elongation of very long chain fatty acids protein 5 ELOVL5 Tchem Non-IDG -1.81279 72.3 189
Lysyl oxidase homolog 1 LOXL1 Tbio Enzyme -2.51621 344.5 145
Cilia- and flagella-associated protein 43 CFAP43 Tdark Non-IDG 0.00000 0