Development Level

Tbio 1,167 | 11,445
Tdark 231 | 6,588
Tchem 218 | 1,598
Tclin 80 | 613

Collection

Ion Channel: IDG Consortium (T... 14 | 99
Kinase: IDG Consortium (Target... 13 | 125
GPCR: IDG Consortium (Targets) 5 | 126
Kinase: IDG Consortium (Comple... 4 | 37
GPCR: IDG Consortium (Complete... 2 | 25

IMPC Phenotype

preweaning lethality, incomple... 52 | 499
preweaning lethality, complete... 50 | 979
abnormal behavior 36 | 298
decreased vertical activity 24 | 208
enlarged heart 23 | 210
decreased body weight 18 | 161
hypoactivity 18 | 132
increased lean body mass 18 | 172
abnormal heart morphology 17 | 162
hyperactivity 17 | 148
abnormal bone structure 16 | 187
decreased total body fat amoun... 16 | 207
abnormal retina morphology 14 | 71
embryonic lethality prior to t... 13 | 278
increased bone mineral content 13 | 108
abnormal embryo size 12 | 220
increased circulating alkaline... 12 | 122
increased mean corpuscular vol... 12 | 92
increased or absent threshold ... 12 | 101
increased startle reflex 12 | 112
abnormal eye morphology 11 | 68
abnormal seminal vesicle morph... 11 | 114
decreased bone mineral content 11 | 151
decreased lean body mass 11 | 135
decreased lymphocyte cell numb... 11 | 83
increased bone mineral density 11 | 72
abnormal lens morphology 10 | 81
cataract 10 | 92
decreased body length 10 | 101
decreased circulating HDL chol... 10 | 68
decreased circulating choleste... 10 | 93
decreased prepulse inhibition 10 | 82
decreased startle reflex 10 | 75
increased circulating HDL chol... 10 | 80
increased circulating triglyce... 10 | 42
abnormal sleep behavior 9 | 70
improved glucose tolerance 9 | 79
increased heart weight 9 | 62
increased hematocrit 9 | 46
increased total body fat amoun... 9 | 134
abnormal behavioral response t... 8 | 66
abnormal coat-hair pigmentatio... 8 | 64
abnormal gait 8 | 69
abnormal spleen morphology 8 | 55
decreased circulating insulin ... 8 | 76
embryonic lethality prior to o... 8 | 239
increased blood urea nitrogen ... 8 | 48
increased circulating choleste... 8 | 66
increased leukocyte cell numbe... 8 | 47
increased neutrophil cell numb... 8 | 46
prenatal lethality prior to he... 8 | 87
thrombocytopenia 8 | 56
decreased circulating alanine ... 7 | 47
decreased circulating calcium ... 7 | 36
decreased heart weight 7 | 27
increased monocyte cell number 7 | 63
short tibia 7 | 97
small superior vagus ganglion 7 | 74
abnormal kidney morphology 6 | 65
abnormal skin morphology 6 | 50
abnormal snout morphology 6 | 23
decreased blood urea nitrogen ... 6 | 51
decreased circulating aspartat... 6 | 34
decreased fasted circulating g... 6 | 65
decreased grip strength 6 | 116
decreased hemoglobin content 6 | 68
decreased leukocyte cell numbe... 6 | 73
decreased mean corpuscular hem... 6 | 31
decreased mean corpuscular vol... 6 | 79
enlarged spleen 6 | 41
increased circulating potassiu... 6 | 29
increased circulating sodium l... 6 | 71
increased heart rate 6 | 23
increased mean platelet volume 6 | 45
mammalian phenotype 6 | 17
abnormal bone mineralization 5 | 38
abnormal epididymis morphology 5 | 42
abnormal locomotor behavior 5 | 24
abnormal lung morphology 5 | 26
abnormal tibia morphology 5 | 14
abnormal vibrissa morphology 5 | 25
corneal opacity 5 | 32
decreased circulating LDL chol... 5 | 38
decreased circulating bilirubi... 5 | 19
decreased circulating glucose ... 5 | 126
decreased circulating potassiu... 5 | 20
decreased circulating triglyce... 5 | 79
decreased erythrocyte cell num... 5 | 62
embryonic growth retardation 5 | 106
hydrometra 5 | 53
impaired righting response 5 | 26
increased body length 5 | 32
increased circulating calcium ... 5 | 34
increased fasted circulating g... 5 | 76
increased lymphocyte cell numb... 5 | 32
decreased circulating fructosa... 4 | 30
impaired glucose tolerance 4 | 75
increased mean corpuscular hem... 4 | 96
male infertility 4 | 123
small testis 4 | 58

Disease

cystic fibrosis 1,696 | 1,696
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Female tissues 1,676 | 17,400
Digestive Tract 1,673 | 17,369
Endocrine System 1,671 | 18,159
Skin and soft tissues 1,667 | 17,230
Blood and immune system 1,660 | 16,909
Urinary Tract 1,648 | 16,678
Male tissues 1,646 | 17,142
Liver and Pancreas 1,641 | 16,750
Respiratory system 1,627 | 16,393
Nervous System 1,623 | 16,725
Cardiovascular System 1,537 | 15,192

Target Family

Non-IDG 982 | 12,091
Enzyme 376 | 4,145
Transcription Factor 111 | 1,400
Kinase 78 | 634
Transporter 58 | 473
Ion Channel 46 | 344
GPCR 25 | 408
Nuclear Receptor 8 | 48
Epigenetic 6 | 242
TF/Epigenetic 4 | 38
oGPCR 2 | 421

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Beta-secretase 2 BACE2 Tchem Enzyme -2.09709 114.0 418
Suppressor of tumorigenicity 14 protein ST14 Tchem Non-IDG -2.50215 338.3 309
Paraneoplastic antigen Ma2 PNMA2 Tbio Non-IDG -2.92781 822.4 113
Beta-1,4-galactosyltransferase 1 B4GALT1 Tbio Enzyme -2.34454 211.1 130
Heme-binding protein 2 HEBP2 Tbio Non-IDG -1.05941 10.8 114
HRAS-like suppressor 2 HRASLS2 Tbio Non-IDG -0.19299 1.65 72
Adhesion G-protein coupled receptor G1 ADGRG1 Tbio GPCR -1.94601 100.6 182
Serine/threonine-protein kinase tousled-like 1 TLK1 Tchem Kinase -1.25235 19.2 305
Nicotinamide riboside kinase 1 NMRK1 Tbio Kinase -0.84939 6.66 143
DnaJ homolog subfamily C member 15 DNAJC15 Tbio Non-IDG -1.67016 50.2 31