Development Level

Tbio 1,075 | 10,625
Tdark 263 | 7,003
Tchem 250 | 1,890
Tclin 77 | 602

Collection

Eligible Ion Channel Proteins 15 | 117
Eligible Kinase Proteins 13 | 134
Eligible non-olfactory GPCR Proteins 5 | 143

IMPC Term

abnormal behavior 31 | 226
preweaning lethality, complete... 29 | 633
preweaning lethality, incomple... 29 | 260
decreased total body fat amoun... 21 | 186
decreased lean body mass 19 | 195
increased circulating alkaline... 18 | 119
decreased body weight 17 | 174
abnormal retina morphology 16 | 100
increased bone mineral content 15 | 92
abnormal bone structure 14 | 131
decreased bone mineral content 13 | 157
decreased circulating HDL chol... 13 | 77
decreased body length 12 | 108
decreased circulating choleste... 12 | 85
hypoactivity 12 | 89
increased lean body mass 12 | 107
increased or absent threshold ... 12 | 128
enlarged heart 11 | 111
hyperactivity 11 | 108
short tibia 11 | 82
abnormal lens morphology 10 | 73
abnormal sleep behavior 10 | 63
decreased heart weight 10 | 44
decreased prepulse inhibition 10 | 52
abnormal bone mineralization 9 | 55
decreased circulating insulin ... 9 | 75
increased bone mineral density 9 | 52
increased mean corpuscular vol... 9 | 91
abnormal behavioral response t... 8 | 52
abnormal retinal pigmentation 8 | 61
decreased bone mineral density 8 | 126
decreased grip strength 8 | 123
decreased rib number 8 | 59
increased exploration in new e... 8 | 56
abnormal coat/hair pigmentatio... 7 | 54
abnormal eye morphology 7 | 38
decreased circulating calcium ... 7 | 33
decreased circulating glucose ... 7 | 121
decreased lumbar vertebrae num... 7 | 62
improved glucose tolerance 7 | 56
increased circulating potassiu... 7 | 31
increased circulating triglyce... 7 | 24
increased startle reflex 7 | 38
abnormal epididymis morphology 6 | 31
abnormal spleen morphology 6 | 36
corneal opacity 6 | 25
decreased circulating alanine ... 6 | 53
decreased vertical activity 6 | 22
increased circulating sodium l... 6 | 71
increased hematocrit 6 | 36
increased sacral vertebrae num... 6 | 62
thrombocytopenia 6 | 46
abnormal embryo size 5 | 112
abnormal gait 5 | 51
abnormal heart morphology 5 | 51
abnormal rib morphology 5 | 28
abnormal seminal vesicle morph... 5 | 47
decreased caudal vertebrae num... 5 | 49
decreased circulating alkaline... 5 | 41
decreased circulating free fat... 5 | 39
decreased circulating potassiu... 5 | 17
decreased circulating triglyce... 5 | 83
decreased eosinophil cell numb... 5 | 41
decreased hemoglobin content 5 | 53
decreased leukocyte cell numbe... 5 | 54
decreased startle reflex 5 | 48
embryonic lethality prior to t... 5 | 187
increased blood urea nitrogen ... 5 | 44
increased circulating HDL chol... 5 | 63
increased circulating choleste... 5 | 53
increased heart rate 5 | 17
increased hemoglobin content 5 | 45
increased leukocyte cell numbe... 5 | 37
increased mean corpuscular hem... 5 | 93
straub tail 5 | 26
abnormal iris morphology 4 | 12
abnormal pelvic girdle bone mo... 4 | 11
abnormal skin morphology 4 | 23
abnormal snout morphology 4 | 18
abnormal tibia morphology 4 | 14
decreased CD4-positive, CD25-p... 4 | 24
decreased blood urea nitrogen ... 4 | 31
decreased circulating LDL chol... 4 | 37
decreased circulating bilirubi... 4 | 14
decreased circulating fructosa... 4 | 31
decreased erythrocyte cell num... 4 | 43
decreased threshold for audito... 4 | 32
enlarged epididymis 4 | 27
enlarged lymph nodes 4 | 27
enlarged spleen 4 | 26
increased body weight 4 | 42
increased circulating amylase ... 4 | 13
increased circulating calcium ... 4 | 32
increased grip strength 4 | 83
increased heart weight 4 | 37
increased total body fat amoun... 4 | 57
prenatal lethality prior to he... 4 | 64
shortened RR interval 4 | 19
abnormal vibrissa morphology 3 | 17
increased circulating total pr... 3 | 20

Disease

cystic fibrosis 1,665 | 1,665
ovarian cancer 8,484 | 8,484
osteosarcoma 7,933 | 7,933
psoriasis 6,685 | 6,685
medulloblastoma, large-cell 6,234 | 6,234
glioblastoma 5,572 | 5,572
lung cancer 4,466 | 4,466
atypical teratoid / rhabdoid tumor 4,369 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 3,289 | 3,289
malignant mesothelioma 3,162 | 3,162
Breast cancer 3,094 | 3,094
pilocytic astrocytoma 3,086 | 3,086
primitive neuroectodermal tumor 3,031 | 3,031
intraductal papillary-mucinous carcinoma (IPMC) 2,988 | 2,988
intraductal papillary-mucinous adenoma (IPMA) 2,956 | 2,956
invasive ductal carcinoma 2,950 | 2,950
oligodendroglioma 2,849 | 2,849
lung carcinoma 2,844 | 2,844
non-small cell lung cancer 2,798 | 2,798
lung adenocarcinoma 2,713 | 2,713
pediatric high grade glioma 2,712 | 2,712
ependymoma 2,514 | 2,514
Cancer 2,346 | 2,346
pancreatic cancer 2,300 | 2,300
interstitial cystitis 2,299 | 2,299
subependymal giant cell astrocytoma 2,287 | 2,287
group 3 medulloblastoma 2,254 | 2,254
astrocytic glioma 2,241 | 2,241
adult high grade glioma 2,148 | 2,148
Carcinoma 2,147 | 2,147
ulcerative colitis 2,087 | 2,087
pituitary cancer 1,972 | 1,972
Pick disease 1,893 | 1,893
group 4 medulloblastoma 1,875 | 1,875
pancreatic ductal adenocarcinoma liver metastasis 1,795 | 1,795
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,663 | 1,663
breast carcinoma 1,614 | 1,614
tuberculosis 1,557 | 1,557
posterior fossa group B ependymoma 1,530 | 1,530
medulloblastoma 1,524 | 1,524
posterior fossa group A ependymoma 1,511 | 1,511
astrocytoma 1,493 | 1,493
sonic hedgehog group medulloblastoma 1,482 | 1,482
colon cancer 1,475 | 1,475
adrenocortical carcinoma 1,427 | 1,427
Multiple myeloma 1,327 | 1,327
primary pancreatic ductal adenocarcinoma 1,271 | 1,271
juvenile dermatomyositis 1,189 | 1,189
Rheumatoid Arthritis 1,160 | 1,160
acute quadriplegic myopathy 1,157 | 1,157
atypical teratoid/rhabdoid tumor 1,095 | 1,095
spina bifida 1,064 | 1,064
cutaneous lupus erythematosus 1,056 | 1,056
nasopharyngeal carcinoma 1,056 | 1,056
Atopic dermatitis 944 | 944
dermatomyositis 933 | 933
active Crohn's disease 918 | 918
non primary Sjogren syndrome sicca 840 | 840
gastric carcinoma 832 | 832
primary Sjogren syndrome 789 | 789
acute myeloid leukemia 780 | 780
Waldenstrons macroglobulinemia 765 | 765
esophageal adenocarcinoma 737 | 737
tuberculosis and treatment for 6 months 686 | 686
progressive supranuclear palsy 674 | 674
aldosterone-producing adenoma 664 | 664
Alzheimer's disease 644 | 644
Obesity 616 | 616
Duchenne muscular dystrophy 602 | 602
Intellectual disability 573 | 573
pancreatic carcinoma 567 | 567
fibroadenoma 557 | 557
Down syndrome 548 | 548
Endometriosis 535 | 535
hepatocellular carcinoma 532 | 532
chronic rhinosinusitis 512 | 512
Schizophrenia 501 | 501
autosomal dominant Emery-Dreifuss muscular dystrophy 499 | 499
Multiple Sclerosis 498 | 498
mucosa-associated lymphoid tissue lymphoma 480 | 480
active ulcerative colitis 477 | 477
Prostatic Neoplasms 471 | 471
IGA Glomerulonephritis 454 | 454
Amyotrophic Lateral Sclerosis 431 | 431
gastric cancer 430 | 430
non-small cell lung carcinoma 413 | 413
Mammary Neoplasms 410 | 410
inflammatory breast cancer 404 | 404
Kidney disease 396 | 396
Neurodegenerative disease 383 | 383
Parkinson's disease 364 | 364
sarcoidosis 358 | 358
Asthma 349 | 349
glioblastoma multiforme 347 | 347
Epilepsy 346 | 346
Polycystic Ovary Syndrome 332 | 332
nephrosclerosis 329 | 329
tuberculosis and treatment for 3 months 327 | 327
Autistic Disorder 320 | 320

Tissue

Digestive Tract 1,651 | 18,473
Female tissues 1,651 | 18,647
Urinary Tract 1,650 | 18,444
Nervous System 1,649 | 18,561
Endocrine System 1,648 | 18,512
Liver and Pancreas 1,648 | 18,136
Male tissues 1,644 | 17,969
Skin and soft tissues 1,643 | 18,115
Cardiovascular System 1,642 | 17,958
Blood and immune system 1,638 | 17,995
Respiratory system 1,636 | 17,484

Target Family

Non-IDG 968 | 11,971
Enzyme 368 | 4,146
Transcription Factor 111 | 1,400
Kinase 74 | 634
Transporter 56 | 473
Ion Channel 45 | 341
GPCR 23 | 406
Nuclear Receptor 8 | 48
Epigenetic 6 | 242
TF/Epigenetic 4 | 38
oGPCR 2 | 421

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Interleukin-1 beta IL1B Tclin Non-IDG -4.34333 22444.2 1345
C-reactive protein CRP Tbio Non-IDG -4.51399 33883.5 1160
Chitinase-3-like protein 1 CHI3L1 Tbio Enzyme -2.73776 668.3 248
Lumican LUM Tbio Non-IDG -2.67820 509.4 209
Interstitial collagenase MMP1 Tchem Enzyme -3.40801 2529.5 682
Glial cell line-derived neurotrophic factor GDNF Tbio Non-IDG -3.30206 2301.5 303
EGF-like repeat and discoidin I-like domain-containing protein 3 EDIL3 Tbio Non-IDG -1.83671 93.1 157
Antileukoproteinase SLPI Tbio Enzyme -2.56514 434.2 290
Probable phospholipid-transporting ATPase IIB ATP9B Tdark Transporter -0.57248 3.74 5
Monocarboxylate transporter 14 SLC16A14 Tdark Transporter -0.69265 4.88 34