Development Level
Tbio | 991 | 10,625 | |
Tchem | 230 | 1,890 | |
Tdark | 161 | 7,003 | |
Tclin | 93 | 602 |
Collection
Eligible Kinase Proteins | 6 | 134 | |
Eligible Ion Channel Proteins | 5 | 117 | |
Eligible non-olfactory GPCR Proteins | 5 | 145 |
IMPC Term
preweaning lethality, complete... | 58 | 633 | |
preweaning lethality, incomple... | 30 | 260 | |
abnormal behavior | 23 | 226 | |
decreased lean body mass | 22 | 195 | |
embryonic lethality prior to t... | 21 | 187 | |
decreased body weight | 20 | 174 | |
decreased total body fat amoun... | 18 | 186 | |
decreased grip strength | 16 | 123 | |
decreased bone mineral content | 15 | 157 | |
increased or absent threshold ... | 15 | 128 | |
abnormal embryo size | 14 | 112 | |
decreased body length | 14 | 108 | |
embryonic lethality prior to o... | 13 | 148 | |
increased circulating alkaline... | 13 | 119 | |
increased mean corpuscular vol... | 13 | 91 | |
abnormal bone structure | 12 | 131 | |
abnormal retina morphology | 12 | 100 | |
decreased circulating glucose ... | 12 | 121 | |
enlarged heart | 12 | 111 | |
decreased bone mineral density | 11 | 126 | |
decreased circulating choleste... | 11 | 85 | |
decreased circulating HDL chol... | 10 | 77 | |
increased bone mineral content | 10 | 92 | |
increased lean body mass | 10 | 107 | |
decreased mean corpuscular vol... | 9 | 50 | |
hyperactivity | 9 | 108 | |
increased startle reflex | 9 | 38 | |
decreased heart weight | 8 | 44 | |
decreased startle reflex | 8 | 48 | |
improved glucose tolerance | 8 | 56 | |
increased circulating calcium ... | 8 | 32 | |
increased fasted circulating g... | 8 | 68 | |
increased mean corpuscular hem... | 8 | 93 | |
short tibia | 8 | 82 | |
abnormal bone mineralization | 7 | 55 | |
decreased circulating serum al... | 7 | 79 | |
decreased circulating triglyce... | 7 | 83 | |
decreased eosinophil cell numb... | 7 | 41 | |
decreased lumbar vertebrae num... | 7 | 62 | |
decreased prepulse inhibition | 7 | 52 | |
female infertility | 7 | 34 | |
hypoactivity | 7 | 89 | |
increased exploration in new e... | 7 | 56 | |
thrombocytopenia | 7 | 46 | |
decreased caudal vertebrae num... | 6 | 49 | |
decreased circulating alanine ... | 6 | 53 | |
decreased circulating insulin ... | 6 | 75 | |
decreased circulating total pr... | 6 | 41 | |
decreased fasted circulating g... | 6 | 49 | |
decreased leukocyte cell numbe... | 6 | 54 | |
increased blood urea nitrogen ... | 6 | 44 | |
increased grip strength | 6 | 83 | |
increased hematocrit | 6 | 36 | |
increased sacral vertebrae num... | 6 | 62 | |
prenatal lethality prior to he... | 6 | 64 | |
abnormal gait | 5 | 51 | |
abnormal heart morphology | 5 | 51 | |
abnormal lens morphology | 5 | 73 | |
abnormal seminal vesicle morph... | 5 | 47 | |
cardiovascular system phenotyp... | 5 | 35 | |
decreased circulating free fat... | 5 | 39 | |
decreased erythrocyte cell num... | 5 | 43 | |
decreased hemoglobin content | 5 | 53 | |
impaired glucose tolerance | 5 | 52 | |
increased bone mineral density | 5 | 52 | |
increased circulating HDL chol... | 5 | 63 | |
increased circulating creatini... | 5 | 29 | |
increased total body fat amoun... | 5 | 57 | |
male infertility | 5 | 62 | |
tremors | 5 | 34 | |
abnormal coat/hair pigmentatio... | 4 | 54 | |
abnormal cranium morphology | 4 | 32 | |
abnormal eye morphology | 4 | 38 | |
abnormal hindbrain development | 4 | 24 | |
abnormal lung morphology | 4 | 15 | |
abnormal midbrain development | 4 | 22 | |
abnormal neural tube closure | 4 | 37 | |
abnormal retinal pigmentation | 4 | 61 | |
abnormal skin appearance | 4 | 8 | |
decreased circulating alkaline... | 4 | 41 | |
decreased circulating glycerol... | 4 | 19 | |
decreased circulating iron lev... | 4 | 25 | |
decreased mean corpuscular hem... | 4 | 34 | |
decreased threshold for audito... | 4 | 32 | |
hydrops fetalis | 4 | 22 | |
impaired righting response | 4 | 19 | |
increased circulating bilirubi... | 4 | 16 | |
increased circulating choleste... | 4 | 53 | |
increased circulating phosphat... | 4 | 24 | |
increased circulating sodium l... | 4 | 71 | |
increased heart weight | 4 | 37 | |
increased rib number | 4 | 41 | |
limb grasping | 4 | 35 | |
abnormal sleep behavior | 3 | 63 | |
decreased rib number | 3 | 59 | |
increased body weight | 3 | 42 | |
increased circulating potassiu... | 3 | 31 | |
increased circulating serum al... | 3 | 25 | |
increased circulating total pr... | 3 | 20 | |
increased hemoglobin content | 3 | 45 |
Disease
Tissue
Digestive Tract | 1,462 | 18,473 | |
Nervous System | 1,462 | 18,561 | |
Liver and Pancreas | 1,461 | 18,136 | |
Male tissues | 1,460 | 17,969 | |
Urinary Tract | 1,459 | 18,444 | |
Female tissues | 1,458 | 18,647 | |
Endocrine System | 1,456 | 18,512 | |
Cardiovascular System | 1,453 | 17,958 | |
Blood and immune system | 1,452 | 17,995 | |
Respiratory system | 1,446 | 17,484 | |
Skin and soft tissues | 1,443 | 18,115 |
Target Family
Non-IDG | 857 | 11,969 | |
Enzyme | 340 | 4,146 | |
Transcription Factor | 93 | 1,400 | |
Kinase | 61 | 634 | |
Transporter | 47 | 473 | |
GPCR | 32 | 408 | |
Ion Channel | 28 | 341 | |
Epigenetic | 9 | 242 | |
Nuclear Receptor | 6 | 48 | |
TF/Epigenetic | 1 | 38 | |
oGPCR | 1 | 421 |
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