Development Level

Tbio 328 | 11,651
Tdark 126 | 6,593
Tchem 31 | 1,388
Tclin 27 | 612

Collection

RFA-RM-18-021 6 | 328
Kinase: IDG Consortium (Target... 3 | 125
Ion Channel: IDG Consortium (T... 2 | 99
GPCR: IDG Consortium (Targets) 1 | 126
Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 19 | 979
preweaning lethality, incomple... 19 | 499
abnormal embryo size 11 | 220
decreased total body fat amoun... 10 | 207
abnormal behavior 9 | 298
abnormal heart morphology 8 | 162
decreased vertical activity 8 | 208
embryonic lethality prior to t... 8 | 278
abnormal seminal vesicle morph... 7 | 114
decreased body weight 7 | 161
hyperactivity 7 | 148
increased lean body mass 7 | 172
enlarged heart 6 | 210
increased bone mineral content 6 | 108
increased mean corpuscular vol... 6 | 92
male infertility 6 | 123
decreased bone mineral density 5 | 126
decreased circulating insulin ... 5 | 76
decreased lean body mass 5 | 135
decreased lymphocyte cell numb... 5 | 83
embryonic lethality prior to o... 5 | 239
increased heart weight 5 | 62
increased startle reflex 5 | 112
abnormal behavioral response t... 4 | 66
abnormal bone structure 4 | 187
decreased prepulse inhibition 4 | 82
decreased startle reflex 4 | 75
embryonic growth retardation 4 | 106
enlarged spleen 4 | 41
hypoactivity 4 | 132
increased blood urea nitrogen ... 4 | 48
increased total body fat amoun... 4 | 134
microphthalmia 4 | 26
abnormal craniofacial morpholo... 3 | 33
abnormal embryo turning 3 | 31
abnormal retina morphology 3 | 71
abnormal sleep behavior 3 | 70
abnormal spleen morphology 3 | 55
decreased body length 3 | 101
decreased bone mineral content 3 | 151
decreased circulating glucose ... 3 | 126
decreased circulating triglyce... 3 | 79
decreased erythrocyte cell num... 3 | 62
decreased leukocyte cell numbe... 3 | 73
edema 3 | 59
increased neutrophil cell numb... 3 | 46
increased or absent threshold ... 3 | 101
prenatal lethality prior to he... 3 | 87
abnormal bone mineralization 2 | 38
abnormal cornea morphology 2 | 31
abnormal cranium morphology 2 | 36
abnormal eye morphology 2 | 68
abnormal facial morphology 2 | 17
abnormal iris morphology 2 | 13
abnormal locomotor activation 2 | 16
abnormal response to tactile s... 2 | 17
abnormal startle reflex 2 | 15
abnormal tail morphology 2 | 25
anophthalmia 2 | 33
cardiovascular system phenotyp... 2 | 36
cataract 2 | 92
convulsive seizures 2 | 13
decreased circulating HDL chol... 2 | 68
decreased circulating bilirubi... 2 | 19
decreased circulating potassiu... 2 | 20
decreased circulating serum al... 2 | 82
decreased grip strength 2 | 116
decreased hematocrit 2 | 46
decreased mean corpuscular hem... 2 | 50
decreased threshold for audito... 2 | 26
female infertility 2 | 60
hydrometra 2 | 53
improved glucose tolerance 2 | 79
increased bone mineral density 2 | 72
increased circulating HDL chol... 2 | 80
increased circulating alkaline... 2 | 122
increased circulating iron lev... 2 | 30
increased circulating triglyce... 2 | 42
increased erythrocyte cell num... 2 | 39
increased grip strength 2 | 41
increased heart rate 2 | 23
increased hematocrit 2 | 46
increased leukocyte cell numbe... 2 | 47
increased mean corpuscular hem... 2 | 96
increased monocyte cell number 2 | 63
limb grasping 2 | 41
short tibia 2 | 97
shortened RR interval 2 | 17
small adrenal glands 2 | 16
small superior vagus ganglion 2 | 74
small testis 2 | 58
thrombocytopenia 2 | 56
abnormal ear morphology 1 | 9
abnormal whole-body plethysmog... 1 | 4
decreased eosinophil cell numb... 1 | 24
decreased red blood cell distr... 1 | 41
decreased total retina thickne... 1 | 17
increased circulating choleste... 1 | 66
thin ventricular wall 1 | 24
tremors 1 | 39

Disease

chronic rhinosinusitis 512 | 512
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,519
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,577
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,290
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,988
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,954
invasive ductal carcinoma 2,951 | 2,950
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,744
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,695
breast carcinoma 1,638 | 1,637
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,108
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Endocrine System 508 | 18,159
Female tissues 506 | 17,400
Male tissues 504 | 17,142
Respiratory system 500 | 16,393
Skin and soft tissues 500 | 17,230
Digestive Tract 499 | 17,369
Blood and immune system 491 | 16,909
Liver and Pancreas 490 | 16,750
Nervous System 490 | 16,725
Urinary Tract 489 | 16,678
Cardiovascular System 439 | 15,192

Target Family

Non-IDG 341 | 12,091
Enzyme 94 | 4,145
Transcription Factor 28 | 1,400
Transporter 15 | 473
Kinase 14 | 634
GPCR 7 | 408
Ion Channel 6 | 344
Nuclear Receptor 5 | 48
Epigenetic 1 | 242
TF/Epigenetic 1 | 38

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Dual specificity protein phosphatase 1 DUSP1 Tchem Enzyme -2.88260 810.9 388
IQ and AAA domain-containing protein 1 IQCA1 Tbio Non-IDG -0.80618 5.26 77
4-aminobutyrate aminotransferase, mitochondrial ABAT Tclin Enzyme -2.02391 104.3 204
Nephronectin NPNT Tbio Non-IDG -1.54450 37.2 104
Cysteine-rich secretory protein 3 CRISP3 Tbio Non-IDG -1.58618 43.2 129
Syndecan-4 SDC4 Tbio Non-IDG -2.39649 274.8 297
Protein wntless homolog WLS Tbio Non-IDG -2.50699 316.3 71
Dynein heavy chain 6, axonemal DNAH6 Tbio Non-IDG -0.53057 4.17 18
Sperm flagellar protein 2 SPEF2 Tdark Non-IDG -1.20840 16.3 33
Fc receptor-like protein 5 FCRL5 Tbio Non-IDG -1.23637 21.0 145