Development Level

Tbio 152 | 10,625
Tchem 45 | 1,890
Tdark 24 | 7,003
Tclin 11 | 602

Collection

GPCR: IDG Consortium (Complete/Control) 1 | 24
GPCR: IDG Consortium (Targets) 1 | 128
Ion Channel: IDG Consortium (Targets) 1 | 102
Kinase: IDG Consortium (Complete/Control) 1 | 37

IMPC Phenotype

preweaning lethality, complete... 9 | 633
preweaning lethality, incomple... 7 | 260
abnormal behavior 4 | 226
abnormal heart morphology 4 | 51
decreased circulating insulin ... 4 | 75
enlarged heart 4 | 111
abnormal skin morphology 3 | 23
decreased body weight 3 | 174
decreased circulating HDL chol... 3 | 77
decreased circulating alanine ... 3 | 53
embryonic lethality prior to t... 3 | 187
hyperactivity 3 | 108
increased bone mineral content 3 | 92
increased circulating alkaline... 3 | 119
short tibia 3 | 82
abnormal bone mineralization 2 | 55
abnormal bone structure 2 | 131
abnormal embryo size 2 | 112
abnormal epididymis morphology 2 | 31
abnormal femur morphology 2 | 14
abnormal joint morphology 2 | 14
abnormal lens morphology 2 | 73
abnormal neural tube morpholog... 2 | 8
abnormal radius morphology 2 | 8
abnormal retina morphology 2 | 100
abnormal startle reflex 2 | 14
abnormal tibia morphology 2 | 14
abnormal ulna morphology 2 | 8
decreased blood urea nitrogen ... 2 | 31
decreased body length 2 | 108
decreased bone mineral density 2 | 126
decreased circulating alkaline... 2 | 41
decreased circulating amylase ... 2 | 24
decreased circulating serum al... 2 | 79
decreased circulating total pr... 2 | 41
decreased circulating triglyce... 2 | 83
decreased grip strength 2 | 123
decreased lean body mass 2 | 195
decreased startle reflex 2 | 48
decreased total body fat amoun... 2 | 186
embryonic lethality prior to o... 2 | 148
improved glucose tolerance 2 | 56
increased bone mineral density 2 | 52
increased or absent threshold ... 2 | 128
prenatal lethality prior to he... 2 | 64
abnormal behavioral response t... 1 | 52
abnormal brain morphology 1 | 6
abnormal cornea morphology 1 | 24
abnormal ear morphology 1 | 5
abnormal embryo turning 1 | 15
abnormal neural tube closure 1 | 37
abnormal optic disc morphology 1 | 10
abnormal pancreas morphology 1 | 6
abnormal pelvic girdle bone mo... 1 | 11
abnormal sleep behavior 1 | 63
abnormal spleen morphology 1 | 36
abnormal tail movements 1 | 12
abnormal testis morphology 1 | 30
abnormal vertebrae morphology 1 | 14
cardiovascular system phenotyp... 1 | 35
convulsive seizures 1 | 11
decreased CD4-positive, alpha ... 1 | 19
decreased CD8-positive, alpha-... 1 | 26
decreased T cell number 1 | 31
decreased bone mineral content 1 | 157
decreased circulating calcium ... 1 | 33
decreased circulating phosphat... 1 | 15
decreased effector memory CD8-... 1 | 24
decreased eosinophil cell numb... 1 | 41
decreased heart rate variabili... 1 | 11
decreased heart weight 1 | 44
decreased lumbar vertebrae num... 1 | 62
decreased mean corpuscular hem... 1 | 34
decreased mean corpuscular vol... 1 | 50
embryonic growth retardation 1 | 28
hydroencephaly 1 | 6
impaired glucose tolerance 1 | 52
increased blood urea nitrogen ... 1 | 44
increased body weight 1 | 42
increased caudal vertebrae num... 1 | 8
increased circulating calcium ... 1 | 32
increased circulating creatini... 1 | 29
increased circulating potassiu... 1 | 31
increased circulating sodium l... 1 | 71
increased circulating total pr... 1 | 20
increased circulating triglyce... 1 | 24
increased fasted circulating g... 1 | 68
increased grip strength 1 | 83
increased hematocrit 1 | 36
increased hemoglobin content 1 | 45
increased prepulse inhibition 1 | 21
increased respiratory quotient 1 | 12
increased sacral vertebrae num... 1 | 62
increased total body fat amoun... 1 | 57
increased vertical activity 1 | 18
oligodactyly 1 | 14
prenatal lethality 1 | 16
short tail 1 | 4
small testis 1 | 37
thrombocytopenia 1 | 46

Disease

chronic lymphosyte leukemia 232 | 232
ovarian cancer 8,491 | 8,491
osteosarcoma 7,933 | 7,933
psoriasis 6,685 | 6,685
medulloblastoma, large-cell 6,234 | 6,234
glioblastoma 5,572 | 5,572
lung cancer 4,473 | 4,473
atypical teratoid / rhabdoid tumor 4,369 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 3,289 | 3,289
malignant mesothelioma 3,163 | 3,163
Breast cancer 3,098 | 3,098
pilocytic astrocytoma 3,086 | 3,086
primitive neuroectodermal tumor 3,031 | 3,031
intraductal papillary-mucinous carcinoma (IPMC) 2,988 | 2,988
intraductal papillary-mucinous adenoma (IPMA) 2,956 | 2,956
invasive ductal carcinoma 2,950 | 2,950
oligodendroglioma 2,849 | 2,849
lung carcinoma 2,844 | 2,844
non-small cell lung cancer 2,798 | 2,798
lung adenocarcinoma 2,714 | 2,714
pediatric high grade glioma 2,712 | 2,712
ependymoma 2,514 | 2,514
Cancer 2,346 | 2,346
pancreatic cancer 2,300 | 2,300
interstitial cystitis 2,299 | 2,299
subependymal giant cell astrocytoma 2,287 | 2,287
group 3 medulloblastoma 2,254 | 2,254
astrocytic glioma 2,241 | 2,241
adult high grade glioma 2,148 | 2,148
Carcinoma 2,147 | 2,147
ulcerative colitis 2,087 | 2,087
pituitary cancer 1,972 | 1,972
Pick disease 1,893 | 1,893
group 4 medulloblastoma 1,875 | 1,875
pancreatic ductal adenocarcinoma liver metastasis 1,795 | 1,795
ductal carcinoma in situ 1,745 | 1,745
cystic fibrosis 1,670 | 1,670
diabetes mellitus 1,663 | 1,663
breast carcinoma 1,614 | 1,614
tuberculosis 1,563 | 1,563
posterior fossa group B ependymoma 1,530 | 1,530
medulloblastoma 1,524 | 1,524
posterior fossa group A ependymoma 1,511 | 1,511
astrocytoma 1,493 | 1,493
sonic hedgehog group medulloblastoma 1,482 | 1,482
colon cancer 1,475 | 1,475
adrenocortical carcinoma 1,427 | 1,427
Multiple myeloma 1,327 | 1,327
primary pancreatic ductal adenocarcinoma 1,271 | 1,271
juvenile dermatomyositis 1,189 | 1,189
Rheumatoid Arthritis 1,170 | 1,170
acute quadriplegic myopathy 1,157 | 1,157
atypical teratoid/rhabdoid tumor 1,095 | 1,095
spina bifida 1,064 | 1,064
cutaneous lupus erythematosus 1,056 | 1,056
nasopharyngeal carcinoma 1,056 | 1,056
dermatomyositis 966 | 966
Atopic dermatitis 944 | 944
active Crohn's disease 918 | 918
non primary Sjogren syndrome sicca 840 | 840
gastric carcinoma 832 | 832
primary Sjogren syndrome 788 | 788
acute myeloid leukemia 785 | 785
Waldenstrons macroglobulinemia 764 | 764
esophageal adenocarcinoma 737 | 737
tuberculosis and treatment for 6 months 686 | 686
progressive supranuclear palsy 674 | 674
aldosterone-producing adenoma 664 | 664
Alzheimer's disease 644 | 644
Obesity 616 | 616
Duchenne muscular dystrophy 602 | 602
Intellectual disability 573 | 573
pancreatic carcinoma 567 | 567
fibroadenoma 557 | 557
hepatocellular carcinoma 550 | 550
Down syndrome 548 | 548
Endometriosis 535 | 535
chronic rhinosinusitis 512 | 512
Schizophrenia 503 | 503
autosomal dominant Emery-Dreifuss muscular dystrophy 499 | 499
Multiple Sclerosis 498 | 498
mucosa-associated lymphoid tissue lymphoma 480 | 480
active ulcerative colitis 477 | 477
Prostatic Neoplasms 471 | 471
IGA Glomerulonephritis 454 | 454
gastric cancer 436 | 436
Amyotrophic Lateral Sclerosis 432 | 432
non-small cell lung carcinoma 413 | 413
Mammary Neoplasms 410 | 410
inflammatory breast cancer 404 | 404
Kidney disease 397 | 397
Neurodegenerative disease 383 | 383
sarcoidosis 368 | 368
Parkinson's disease 364 | 364
Asthma 349 | 349
glioblastoma multiforme 347 | 347
Epilepsy 346 | 346
Polycystic Ovary Syndrome 334 | 334
nephrosclerosis 329 | 329
tuberculosis and treatment for 3 months 327 | 327
Autistic Disorder 320 | 320

Tissue

Digestive Tract 230 | 18,472
Liver and Pancreas 230 | 18,135
Male tissues 230 | 17,968
Nervous System 230 | 18,560
Urinary Tract 230 | 18,443
Blood and immune system 229 | 17,994
Endocrine System 229 | 18,511
Female tissues 229 | 18,646
Cardiovascular System 228 | 17,957
Respiratory system 228 | 17,483
Skin and soft tissues 225 | 18,114

Target Family

Non-IDG 145 | 11,969
Enzyme 33 | 4,146
Transcription Factor 31 | 1,400
GPCR 9 | 408
Kinase 7 | 634
Ion Channel 3 | 341
Transporter 3 | 473
Nuclear Receptor 1 | 48

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Dual specificity protein phosphatase 1 DUSP1 Tchem Enzyme -2.86495 767.9 361
Interferon gamma receptor 1 IFNGR1 Tchem Non-IDG -2.19638 160.9 450
Galectin-3 LGALS3 Tchem Non-IDG -3.33005 2249.5 911
Myristoylated alanine-rich C-kinase substrate MARCKS Tbio Enzyme -2.67051 512.2 639
Alternative prion protein PRNP Tbio Non-IDG -3.44085 5471.9 0
A-kinase anchor protein 12 AKAP12 Tbio Enzyme -1.97288 119.1 151
Complement receptor type 1 CR1 Tbio Non-IDG -3.34929 2279.9 502
Testis-specific Y-encoded-like protein 5 TSPYL5 Tbio Non-IDG -0.70609 5.15 68
Dihydropyrimidine dehydrogenase [NADP(+)] DPYD Tclin Enzyme -2.60310 374.7 140
Alpha-1-antitrypsin SERPINA1 Tbio Non-IDG -3.73976 5495.0 809