Development Level

Tbio 150 | 11,651
Tchem 23 | 1,388
Tdark 23 | 6,593
Tclin 8 | 612

Collection

RFA-RM-18-021 3 | 328
GPCR: IDG Consortium (Targets) 1 | 126
Ion Channel: IDG Consortium (T... 1 | 99
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

decreased vertical activity 7 | 208
abnormal behavior 5 | 298
enlarged heart 5 | 210
preweaning lethality, complete... 5 | 979
preweaning lethality, incomple... 5 | 499
abnormal heart morphology 4 | 162
abnormal skin morphology 4 | 50
decreased circulating insulin ... 4 | 76
abnormal lens morphology 3 | 81
decreased circulating alanine ... 3 | 47
decreased circulating triglyce... 3 | 79
decreased total body fat amoun... 3 | 207
impaired glucose tolerance 3 | 75
abnormal bone mineralization 2 | 38
abnormal pancreas morphology 2 | 13
abnormal seminal vesicle morph... 2 | 114
abnormal spleen morphology 2 | 55
abnormal vertebrae morphology 2 | 18
cataract 2 | 92
decreased blood urea nitrogen ... 2 | 51
decreased body length 2 | 101
decreased body weight 2 | 161
decreased circulating HDL chol... 2 | 68
decreased circulating amylase ... 2 | 28
decreased circulating phosphat... 2 | 27
decreased mean corpuscular hem... 2 | 50
decreased startle reflex 2 | 75
embryonic lethality prior to t... 2 | 278
enlarged spleen 2 | 41
hypoactivity 2 | 132
improved glucose tolerance 2 | 79
increased circulating alkaline... 2 | 122
increased fasted circulating g... 2 | 76
increased total body fat amoun... 2 | 134
increased vertical activity 2 | 24
prenatal lethality prior to he... 2 | 87
short tibia 2 | 97
small superior vagus ganglion 2 | 74
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal brain morphology 1 | 13
abnormal cecum morphology 1 | 7
abnormal cornea morphology 1 | 31
abnormal embryo size 1 | 220
abnormal epididymis morphology 1 | 42
abnormal eye morphology 1 | 68
abnormal femur morphology 1 | 14
abnormal heart left ventricle ... 1 | 16
abnormal joint morphology 1 | 23
abnormal neural tube morpholog... 1 | 12
abnormal radius morphology 1 | 8
abnormal sleep behavior 1 | 70
abnormal startle reflex 1 | 15
abnormal stomach morphology 1 | 10
abnormal tail morphology 1 | 25
abnormal tail movements 1 | 12
abnormal testis morphology 1 | 43
abnormal thymus morphology 1 | 7
abnormal tibia morphology 1 | 14
abnormal ulna morphology 1 | 8
abnormal vertebral arch morpho... 1 | 9
cardiovascular system phenotyp... 1 | 36
convulsive seizures 1 | 13
decreased CD4-positive, alpha ... 1 | 7
decreased CD8-positive, alpha-... 1 | 8
decreased T cell number 1 | 15
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating LDL chol... 1 | 38
decreased circulating alkaline... 1 | 46
decreased circulating calcium ... 1 | 36
decreased circulating choleste... 1 | 93
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased heart rate variabili... 1 | 13
decreased mean platelet volume 1 | 25
decreased threshold for audito... 1 | 26
embryonic lethality prior to o... 1 | 239
hydroencephaly 1 | 14
hydrometra 1 | 53
hyperactivity 1 | 148
increased blood urea nitrogen ... 1 | 48
increased body weight 1 | 25
increased bone mineral density 1 | 72
increased circulating calcium ... 1 | 34
increased circulating potassiu... 1 | 29
increased circulating sodium l... 1 | 71
increased heart weight 1 | 62
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
long tail 1 | 1
mammalian phenotype 1 | 17
microphthalmia 1 | 26
pale yolk sac 1 | 25
prenatal lethality 1 | 28
small testis 1 | 58
small thymus 1 | 16
thick tail 1 | 1

Disease

chronic lymphosyte leukemia 204 | 204
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Blood and immune system 187 | 16,909
Digestive Tract 187 | 17,369
Endocrine System 187 | 18,159
Female tissues 187 | 17,400
Liver and Pancreas 187 | 16,750
Male tissues 187 | 17,142
Skin and soft tissues 187 | 17,230
Urinary Tract 187 | 16,678
Respiratory system 186 | 16,393
Cardiovascular System 185 | 15,192
Nervous System 184 | 16,725

Target Family

Non-IDG 133 | 12,091
Transcription Factor 28 | 1,400
Enzyme 27 | 4,145
GPCR 7 | 408
Ion Channel 3 | 344
Kinase 3 | 634
Transporter 2 | 473
Nuclear Receptor 1 | 48

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Dual specificity protein phosphatase 1 DUSP1 Tchem Enzyme -2.88260 810.9 388
Paraneoplastic antigen Ma2 PNMA2 Tbio Non-IDG -2.92781 822.4 113
Nicotinamide phosphoribosyltransferase NAMPT Tchem Enzyme -2.94790 1054.3 667
Galectin-2 LGALS2 Tbio Non-IDG -1.12300 13.4 172
Fc receptor-like protein 5 FCRL5 Tbio Non-IDG -1.23637 21.0 145
Interferon gamma receptor 1 IFNGR1 Tbio Non-IDG -2.23009 172.7 518
Platelet glycoprotein 4 CD36 Tbio Non-IDG -2.63884 376.0 1155
Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 PAG1 Tbio Non-IDG -1.69647 50.1 216
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 SAMHD1 Tbio Enzyme -3.96722 8709.0 274
BH3-interacting domain death agonist BID Tbio Non-IDG -1.85313 58.9 981