Development Level

Tbio 365 | 11,178
Tchem 74 | 1,885
Tdark 42 | 6,569
Tclin 11 | 612

Collection

Kinase: IDG Consortium (Target... 3 | 125
GPCR: IDG Consortium (Targets) 1 | 126
Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

preweaning lethality, complete... 28 | 979
preweaning lethality, incomple... 17 | 499
abnormal behavior 10 | 298
decreased total body fat amoun... 10 | 207
embryonic lethality prior to t... 10 | 278
decreased body weight 9 | 161
increased bone mineral content 8 | 108
increased lean body mass 8 | 172
enlarged heart 7 | 210
hypoactivity 7 | 132
abnormal embryo size 6 | 220
decreased bone mineral content 6 | 151
decreased bone mineral density 6 | 126
decreased lean body mass 6 | 135
decreased vertical activity 6 | 208
increased bone mineral density 6 | 72
increased mean corpuscular vol... 6 | 92
abnormal bone structure 5 | 187
abnormal coat-hair pigmentatio... 5 | 64
decreased grip strength 5 | 116
embryonic growth retardation 5 | 106
increased startle reflex 5 | 112
abnormal bone mineralization 4 | 38
abnormal eye morphology 4 | 68
abnormal heart morphology 4 | 162
cataract 4 | 92
decreased caudal vertebrae num... 4 | 53
decreased circulating HDL chol... 4 | 68
decreased circulating LDL chol... 4 | 38
decreased circulating choleste... 4 | 93
decreased circulating glucose ... 4 | 126
decreased circulating insulin ... 4 | 76
decreased heart weight 4 | 27
decreased leukocyte cell numbe... 4 | 73
decreased lymphocyte cell numb... 4 | 83
decreased mean corpuscular hem... 4 | 31
impaired glucose tolerance 4 | 75
increased fasted circulating g... 4 | 76
increased heart weight 4 | 62
prenatal lethality prior to he... 4 | 87
abnormal coat- hair morphology 3 | 19
abnormal retina morphology 3 | 71
decreased circulating alanine ... 3 | 47
decreased neutrophil cell numb... 3 | 42
decreased prepulse inhibition 3 | 82
embryonic lethality prior to o... 3 | 239
hyperactivity 3 | 148
improved glucose tolerance 3 | 79
increased circulating chloride... 3 | 41
increased circulating sodium l... 3 | 71
increased mean corpuscular hem... 3 | 36
increased monocyte cell number 3 | 63
increased total body fat amoun... 3 | 134
thrombocytopenia 3 | 56
tremors 3 | 39
abnormal coat appearance 2 | 31
abnormal epididymis morphology 2 | 42
abnormal joint morphology 2 | 23
abnormal lens morphology 2 | 81
abnormal locomotor behavior 2 | 24
abnormal lung morphology 2 | 26
abnormal pericardium morpholog... 2 | 26
abnormal seminal vesicle morph... 2 | 114
abnormal sensory capabilities-... 2 | 8
abnormal sleep behavior 2 | 70
brachydactyly 2 | 19
corneal opacity 2 | 32
decreased body length 2 | 101
decreased circulating creatini... 2 | 39
decreased circulating free fat... 2 | 31
decreased circulating potassiu... 2 | 20
decreased circulating serum al... 2 | 82
decreased mean corpuscular vol... 2 | 79
decreased mean platelet volume 2 | 25
enlarged epididymis 2 | 31
enlarged liver 2 | 2
enlarged spleen 2 | 41
increased body length 2 | 32
increased body weight 2 | 25
increased circulating HDL chol... 2 | 80
increased circulating bilirubi... 2 | 16
increased circulating calcium ... 2 | 34
increased circulating glucose ... 2 | 24
increased circulating phosphat... 2 | 26
increased circulating triglyce... 2 | 42
increased heart rate 2 | 23
increased hematocrit 2 | 46
increased leukocyte cell numbe... 2 | 47
increased lymphocyte cell numb... 2 | 32
increased mean corpuscular hem... 2 | 96
increased mean platelet volume 2 | 45
increased or absent threshold ... 2 | 101
increased vertical activity 2 | 24
limb grasping 2 | 41
mammalian phenotype 2 | 17
short tibia 2 | 97
shortened ST segment 2 | 10
small seminal vesicle 2 | 10
syndactyly 2 | 23
increased circulating iron lev... 1 | 30

Disease

autosomal dominant Emery-Dreifuss muscular dystrophy 492 | 492
Carcinoma 11,192 | 11,192
ovarian cancer 8,297 | 8,297
osteosarcoma 7,766 | 7,766
psoriasis 6,514 | 6,514
medulloblastoma, large-cell 6,086 | 6,086
glioblastoma 5,635 | 5,635
atypical teratoid / rhabdoid tumor 4,971 | 4,971
lung cancer 4,607 | 4,607
ependymoma 4,559 | 4,559
group 3 medulloblastoma 4,002 | 4,002
adult high grade glioma 3,701 | 3,701
Breast cancer 3,469 | 3,469
intraductal papillary-mucinous neoplasm (IPMN) 3,204 | 3,204
malignant mesothelioma 3,135 | 3,135
Astrocytoma, Pilocytic 3,006 | 3,006
primitive neuroectodermal tumor 2,957 | 2,957
intraductal papillary-mucinous carcinoma (IPMC) 2,902 | 2,902
intraductal papillary-mucinous adenoma (IPMA) 2,872 | 2,872
invasive ductal carcinoma 2,867 | 2,867
non-small cell lung cancer 2,799 | 2,799
oligodendroglioma 2,768 | 2,768
lung carcinoma 2,755 | 2,755
lung adenocarcinoma 2,627 | 2,627
Kidney cancer 2,548 | 2,548
astrocytic glioma 2,530 | 2,530
Cancer 2,388 | 2,388
pancreatic cancer 2,322 | 2,322
interstitial cystitis 2,237 | 2,237
subependymal giant cell astrocytoma 2,230 | 2,230
tuberculosis 1,963 | 1,963
pituitary cancer 1,915 | 1,915
pancreatic ductal adenocarcinoma liver metastasis 1,911 | 1,911
Pick disease 1,856 | 1,856
group 4 medulloblastoma 1,806 | 1,806
ulcerative colitis 1,765 | 1,765
ductal carcinoma in situ 1,686 | 1,686
diabetes mellitus 1,683 | 1,683
cystic fibrosis 1,629 | 1,629
breast carcinoma 1,589 | 1,589
colon cancer 1,428 | 1,428
Autosomal recessive predisposition 1,407 | 1,407
adrenocortical carcinoma 1,385 | 1,385
Multiple myeloma 1,296 | 1,296
Rheumatoid arthritis 1,156 | 1,156
juvenile dermatomyositis 1,147 | 1,147
Schizophrenia 1,136 | 1,136
acute quadriplegic myopathy 1,133 | 1,133
astrocytoma 1,113 | 1,113
primary pancreatic ductal adenocarcinoma 1,071 | 1,071
spina bifida 1,053 | 1,053
pediatric high grade glioma 1,035 | 1,035
nasopharyngeal carcinoma 1,024 | 1,024
cutaneous lupus erythematosus 1,016 | 1,016
Intellectual disability 998 | 998
dermatomyositis 941 | 941
Atopic dermatitis 915 | 915
active Crohn's disease 882 | 882
non primary Sjogren syndrome sicca 861 | 861
gastric carcinoma 781 | 781
Epilepsy 775 | 775
acute myeloid leukemia 760 | 760
Waldenstrons macroglobulinemia 742 | 742
active ulcerative colitis 736 | 736
Liver Cirrhosis, Experimental 733 | 733
primary Sjogren syndrome 710 | 710
medulloblastoma 702 | 702
esophageal adenocarcinoma 696 | 696
Melanoma 689 | 689
progressive supranuclear palsy 656 | 656
Obesity 655 | 655
Bipolar Disorder 646 | 646
aldosterone-producing adenoma 646 | 646
Alzheimer's disease 640 | 640
Dull intelligence 634 | 634
Low intelligence 634 | 634
Mental Retardation 634 | 634
Mental deficiency 634 | 634
Poor school performance 634 | 634
Cognitive delay 596 | 596
Global developmental delay 596 | 596
Mental and motor retardation 596 | 596
Liver cancer 589 | 589
Duchenne muscular dystrophy 587 | 587
Seizures 584 | 584
Muscle hypotonia 562 | 562
pancreatic carcinoma 555 | 555
fibroadenoma 538 | 538
hepatocellular carcinoma 536 | 536
Multiple Sclerosis 527 | 527
Endometriosis 521 | 521
Short stature 514 | 514
chronic rhinosinusitis 505 | 505
Down syndrome 480 | 480
mucosa-associated lymphoid tissue lymphoma 473 | 473
Prostatic Neoplasms 472 | 472
sonic hedgehog group medulloblastoma 459 | 459
posterior fossa group A ependymoma 456 | 456
Skin cancer 451 | 451
gastric cancer 445 | 445

Tissue

Endocrine System 488 | 18,159
Skin and soft tissues 488 | 17,230
Digestive Tract 487 | 17,369
Male tissues 487 | 17,142
Cardiovascular System 485 | 15,192
Female tissues 485 | 17,400
Nervous System 485 | 16,725
Liver and Pancreas 484 | 16,750
Blood and immune system 483 | 16,909
Urinary Tract 483 | 16,678
Respiratory system 479 | 16,393

Target Family

Non-IDG 331 | 12,091
Enzyme 84 | 4,145
Transcription Factor 33 | 1,400
Kinase 18 | 634
Transporter 13 | 473
GPCR 5 | 408
Ion Channel 4 | 344
Epigenetic 2 | 242
Nuclear Receptor 1 | 48
TF/Epigenetic 1 | 38

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Nidogen-2 NID2 Tbio Non-IDG -1.62355 40.1 116
Transforming growth factor beta receptor type 3 TGFBR3 Tbio Non-IDG -1.92250 80.6 270
Protein CYR61 CYR61 Tbio Non-IDG -2.43164 320.5 423
Dehydrogenase/reductase SDR family member 7C DHRS7C Tdark Enzyme -0.30702 2.41 87
BDNF/NT-3 growth factors receptor NTRK2 Tchem Kinase -3.14477 1170.3 947
Diamine acetyltransferase 1 SAT1 Tbio Enzyme -2.60045 409.5 159
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like BNIP3L Tbio Non-IDG -2.20837 153.7 355
SH3 domain-binding protein 5 SH3BP5 Tbio Non-IDG -2.76639 566.7 116
Zinc finger E-box-binding homeobox 2 ZEB2 Tbio Transcription Factor -2.49656 262.6 474
Interferon-induced, double-stranded RNA-activated protein kinase EIF2AK2 Tbio Kinase -1.96184 89.9 894