Development Level

Tbio 484 | 11,651
Tdark 96 | 6,593
Tchem 57 | 1,388
Tclin 28 | 612

Collection

RFA-RM-18-021 9 | 328
Kinase: IDG Consortium (Target... 6 | 125
Kinase: IDG Consortium (Comple... 4 | 37
Ion Channel: IDG Consortium (T... 2 | 99
GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

preweaning lethality, complete... 35 | 979
abnormal behavior 18 | 298
preweaning lethality, incomple... 17 | 499
decreased total body fat amoun... 12 | 207
decreased vertical activity 10 | 208
increased lean body mass 10 | 172
hyperactivity 9 | 148
increased bone mineral content 9 | 108
increased mean corpuscular vol... 9 | 92
decreased body weight 8 | 161
embryonic lethality prior to t... 8 | 278
increased circulating alkaline... 8 | 122
abnormal heart morphology 7 | 162
enlarged heart 7 | 210
increased startle reflex 7 | 112
thrombocytopenia 7 | 56
cataract 6 | 92
decreased circulating glucose ... 6 | 126
decreased grip strength 6 | 116
decreased leukocyte cell numbe... 6 | 73
hypoactivity 6 | 132
increased or absent threshold ... 6 | 101
abnormal bone structure 5 | 187
abnormal coat-hair pigmentatio... 5 | 64
abnormal embryo size 5 | 220
abnormal gait 5 | 69
abnormal lens morphology 5 | 81
decreased body length 5 | 101
decreased bone mineral content 5 | 151
decreased circulating serum al... 5 | 82
decreased circulating triglyce... 5 | 79
embryonic lethality prior to o... 5 | 239
increased fasted circulating g... 5 | 76
increased mean corpuscular hem... 5 | 96
abnormal eye morphology 4 | 68
decreased fasted circulating g... 4 | 65
decreased mean corpuscular vol... 4 | 79
edema 4 | 59
improved glucose tolerance 4 | 79
increased circulating potassiu... 4 | 29
increased circulating sodium l... 4 | 71
increased circulating triglyce... 4 | 42
increased mean platelet volume 4 | 45
male infertility 4 | 123
abnormal joint morphology 3 | 23
abnormal kidney morphology 3 | 65
abnormal retina morphology 3 | 71
abnormal sleep behavior 3 | 70
decreased circulating HDL chol... 3 | 68
decreased circulating choleste... 3 | 93
decreased erythrocyte cell num... 3 | 62
decreased lean body mass 3 | 135
decreased neutrophil cell numb... 3 | 42
decreased startle reflex 3 | 75
increased blood urea nitrogen ... 3 | 48
increased body length 3 | 32
increased bone mineral density 3 | 72
increased vertical activity 3 | 24
abnormal bone mineralization 2 | 38
abnormal cornea morphology 2 | 31
abnormal iris morphology 2 | 13
abnormal seminal vesicle morph... 2 | 114
abnormal snout morphology 2 | 23
abnormal spleen morphology 2 | 55
abnormal tail morphology 2 | 25
abnormal tibia morphology 2 | 14
abnormal tooth morphology 2 | 24
absent startle reflex 2 | 24
anophthalmia 2 | 33
decreased blood urea nitrogen ... 2 | 51
decreased circulating aspartat... 2 | 34
decreased circulating insulin ... 2 | 76
decreased circulating total pr... 2 | 49
decreased heart left ventricle... 2 | 28
decreased hemoglobin content 2 | 68
decreased lymphocyte cell numb... 2 | 83
decreased mean corpuscular hem... 2 | 50
decreased mean corpuscular hem... 2 | 31
decreased prepulse inhibition 2 | 82
decreased red blood cell distr... 2 | 41
enlarged kidney 2 | 14
enlarged spleen 2 | 41
impaired pupillary reflex 2 | 26
increased circulating aspartat... 2 | 15
increased circulating chloride... 2 | 41
increased circulating choleste... 2 | 66
increased circulating magnesiu... 2 | 10
increased erythrocyte cell num... 2 | 39
increased heart weight 2 | 62
increased kidney weight 2 | 6
increased total body fat amoun... 2 | 134
mammalian phenotype 2 | 17
microphthalmia 2 | 26
pale yolk sac 2 | 25
persistence of hyaloid vascula... 2 | 33
prolonged QT interval 2 | 38
tremors 2 | 39
abnormal craniofacial morpholo... 1 | 33
decreased IgG1 level 1 | 8
decreased circulating amylase ... 1 | 28

Disease

aldosterone-producing adenoma 665 | 665
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Endocrine System 662 | 18,159
Digestive Tract 660 | 17,369
Skin and soft tissues 659 | 17,230
Female tissues 658 | 17,400
Male tissues 658 | 17,142
Liver and Pancreas 656 | 16,750
Urinary Tract 655 | 16,678
Nervous System 654 | 16,725
Respiratory system 651 | 16,393
Blood and immune system 647 | 16,909
Cardiovascular System 637 | 15,192

Target Family

Non-IDG 376 | 12,091
Enzyme 152 | 4,145
Transcription Factor 52 | 1,400
Kinase 31 | 634
Transporter 19 | 473
Epigenetic 11 | 242
GPCR 11 | 408
Ion Channel 9 | 344
Nuclear Receptor 3 | 48
TF/Epigenetic 1 | 38

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Epithelial membrane protein 2 EMP2 Tbio Non-IDG -2.30856 210.6 116
Paraspeckle component 1 PSPC1 Tbio Non-IDG -1.75415 48.3 19
Ras-related protein Rab-22A RAB22A Tbio Enzyme -1.40824 19.7 123
Paraneoplastic antigen Ma2 PNMA2 Tbio Non-IDG -2.92781 822.4 113
Transcription factor HES-1 HES1 Tbio Transcription Factor -1.77409 55.5 444
Protein arginine methyltransferase NDUFAF7, mitochondrial NDUFAF7 Tbio Enzyme -0.45102 2.70 64
Endoplasmic reticulum junction formation protein lunapark LNPK Tbio Non-IDG -1.07127 11.1 9
Macrophage receptor MARCO MARCO Tbio Non-IDG -2.37206 210.3 189
Chromobox protein homolog 3 CBX3 Tbio Epigenetic -2.00023 90.5 366
Collagen and calcium-binding EGF domain-containing protein 1 CCBE1 Tbio Non-IDG -1.27652 20.3 165