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Development Level

Tbio 84 | 11,445
Tchem 19 | 1,598
Tclin 15 | 613
Tdark 13 | 6,588

Collection

Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

abnormal heart morphology 6 | 162
decreased vertical activity 5 | 208
enlarged heart 5 | 210
preweaning lethality, complete... 4 | 979
abnormal behavior 3 | 298
decreased bone mineral content 3 | 151
increased total body fat amoun... 3 | 134
preweaning lethality, incomple... 3 | 499
abnormal embryo size 2 | 220
abnormal eye morphology 2 | 68
decreased blood urea nitrogen ... 2 | 51
decreased circulating insulin ... 2 | 76
decreased circulating triglyce... 2 | 79
decreased lean body mass 2 | 135
hyperactivity 2 | 148
increased or absent threshold ... 2 | 101
increased vertical activity 2 | 24
abnormal behavioral response t... 1 | 66
abnormal coat- hair morphology 1 | 19
abnormal facial morphology 1 | 17
abnormal gait 1 | 69
abnormal hair growth 1 | 10
abnormal head shape 1 | 10
abnormal kidney morphology 1 | 65
abnormal liver morphology 1 | 17
abnormal lung morphology 1 | 26
abnormal outer ear morphology 1 | 3
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
abnormal sleep behavior 1 | 70
abnormal tail morphology 1 | 25
absent startle reflex 1 | 24
absent testes 1 | 6
anophthalmia 1 | 33
cataract 1 | 92
corneal opacity 1 | 32
decreased basophil cell number 1 | 16
decreased circulating alkaline... 1 | 46
decreased circulating amylase ... 1 | 28
decreased circulating glucose ... 1 | 126
decreased circulating potassiu... 1 | 20
decreased circulating sodium l... 1 | 22
decreased eosinophil cell numb... 1 | 24
decreased grip strength 1 | 116
decreased mean platelet volume 1 | 25
decreased total body fat amoun... 1 | 207
enlarged kidney 1 | 14
improved glucose tolerance 1 | 79
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating bilirubi... 1 | 16
increased circulating iron lev... 1 | 30
increased circulating serum al... 1 | 22
increased circulating sodium l... 1 | 71
increased grip strength 1 | 41
increased lean body mass 1 | 172
microphthalmia 1 | 26
prenatal lethality prior to he... 1 | 87
short tibia 1 | 97
shortened ST segment 1 | 10
small superior vagus ganglion 1 | 74
thrombocytosis 1 | 27

Disease

adrenocortical adenoma 131 | 131
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Digestive Tract 131 | 17,369
Endocrine System 131 | 18,159
Female tissues 131 | 17,400
Liver and Pancreas 131 | 16,750
Skin and soft tissues 131 | 17,230
Urinary Tract 131 | 16,678
Male tissues 130 | 17,142
Blood and immune system 129 | 16,909
Respiratory system 129 | 16,393
Nervous System 127 | 16,725
Cardiovascular System 123 | 15,192

Target Family

Non-IDG 79 | 12,091
Enzyme 25 | 4,145
Kinase 9 | 634
GPCR 7 | 408
Transcription Factor 7 | 1,400
Transporter 2 | 473
Epigenetic 1 | 242
Ion Channel 1 | 344

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Tubulin beta-6 chain TUBB6 Tclin Non-IDG -0.94163 8.01 85
UDP-N-acetylhexosamine pyrophosphorylase-like protein 1 UAP1L1 Tdark Enzyme 0.90 0.11 70
Transcription elongation factor A protein-like 7 TCEAL7 Tbio Non-IDG -0.70919 5.68 38
Protocadherin-18 PCDH18 Tbio Non-IDG -0.69395 5.31 87
Zinc finger protein 711 ZNF711 Tbio Transcription Factor -0.83546 5.36 36
WAP four-disulfide core domain protein 1 WFDC1 Tbio Non-IDG -1.94592 87.9 127
Fatty acid-binding protein, adipocyte FABP4 Tchem Non-IDG -2.73935 617.7 605
Angiopoietin-related protein 1 ANGPTL1 Tbio Non-IDG -1.27029 19.3 252
PWWP domain-containing protein MUM1L1 MUM1L1 Tdark Non-IDG 0.44 0.27 71
A disintegrin and metalloproteinase with thrombospondin motifs 1 ADAMTS1 Tchem Enzyme -2.44459 279.8 227