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Development Level

Tbio 79 | 11,178
Tchem 20 | 1,885
Tclin 15 | 612
Tdark 13 | 6,569

Collection

Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

abnormal heart morphology 5 | 162
decreased vertical activity 5 | 208
enlarged heart 4 | 210
preweaning lethality, complete... 4 | 979
abnormal behavior 3 | 298
decreased bone mineral content 3 | 151
increased total body fat amoun... 3 | 134
preweaning lethality, incomple... 3 | 499
abnormal embryo size 2 | 220
abnormal eye morphology 2 | 68
decreased blood urea nitrogen ... 2 | 51
decreased circulating insulin ... 2 | 76
decreased circulating triglyce... 2 | 79
decreased lean body mass 2 | 135
hyperactivity 2 | 148
increased or absent threshold ... 2 | 101
increased vertical activity 2 | 24
abnormal behavioral response t... 1 | 66
abnormal coat- hair morphology 1 | 19
abnormal facial morphology 1 | 17
abnormal gait 1 | 69
abnormal hair growth 1 | 10
abnormal head shape 1 | 10
abnormal liver morphology 1 | 17
abnormal lung morphology 1 | 26
abnormal outer ear morphology 1 | 3
abnormal seminal vesicle morph... 1 | 114
abnormal sleep behavior 1 | 70
abnormal tail morphology 1 | 25
absent startle reflex 1 | 24
absent testes 1 | 6
anophthalmia 1 | 33
cataract 1 | 92
corneal opacity 1 | 32
decreased basophil cell number 1 | 16
decreased circulating alkaline... 1 | 46
decreased circulating amylase ... 1 | 28
decreased circulating glucose ... 1 | 126
decreased circulating potassiu... 1 | 20
decreased circulating sodium l... 1 | 22
decreased eosinophil cell numb... 1 | 24
decreased grip strength 1 | 116
decreased mean platelet volume 1 | 25
decreased total body fat amoun... 1 | 207
improved glucose tolerance 1 | 79
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating bilirubi... 1 | 16
increased circulating iron lev... 1 | 30
increased circulating serum al... 1 | 22
increased circulating sodium l... 1 | 71
increased grip strength 1 | 41
increased lean body mass 1 | 172
microphthalmia 1 | 26
prenatal lethality prior to he... 1 | 87
short tibia 1 | 97
shortened ST segment 1 | 10
small superior vagus ganglion 1 | 74
thrombocytosis 1 | 27

Disease

adrenocortical adenoma 127 | 127
Carcinoma 11,192 | 11,192
ovarian cancer 8,297 | 8,297
osteosarcoma 7,766 | 7,766
psoriasis 6,514 | 6,514
medulloblastoma, large-cell 6,086 | 6,086
glioblastoma 5,635 | 5,635
atypical teratoid / rhabdoid tumor 4,971 | 4,971
lung cancer 4,607 | 4,607
ependymoma 4,559 | 4,559
group 3 medulloblastoma 4,002 | 4,002
adult high grade glioma 3,701 | 3,701
Breast cancer 3,469 | 3,469
intraductal papillary-mucinous neoplasm (IPMN) 3,204 | 3,204
malignant mesothelioma 3,135 | 3,135
Astrocytoma, Pilocytic 3,006 | 3,006
primitive neuroectodermal tumor 2,957 | 2,957
intraductal papillary-mucinous carcinoma (IPMC) 2,902 | 2,902
intraductal papillary-mucinous adenoma (IPMA) 2,872 | 2,872
invasive ductal carcinoma 2,867 | 2,867
non-small cell lung cancer 2,799 | 2,799
oligodendroglioma 2,768 | 2,768
lung carcinoma 2,755 | 2,755
lung adenocarcinoma 2,627 | 2,627
Kidney cancer 2,548 | 2,548
astrocytic glioma 2,530 | 2,530
Cancer 2,388 | 2,388
pancreatic cancer 2,322 | 2,322
interstitial cystitis 2,237 | 2,237
subependymal giant cell astrocytoma 2,230 | 2,230
tuberculosis 1,963 | 1,963
pituitary cancer 1,915 | 1,915
pancreatic ductal adenocarcinoma liver metastasis 1,911 | 1,911
Pick disease 1,856 | 1,856
group 4 medulloblastoma 1,806 | 1,806
ulcerative colitis 1,765 | 1,765
ductal carcinoma in situ 1,686 | 1,686
diabetes mellitus 1,683 | 1,683
cystic fibrosis 1,629 | 1,629
breast carcinoma 1,589 | 1,589
colon cancer 1,428 | 1,428
Autosomal recessive predisposition 1,407 | 1,407
adrenocortical carcinoma 1,385 | 1,385
Multiple myeloma 1,296 | 1,296
Rheumatoid arthritis 1,156 | 1,156
juvenile dermatomyositis 1,147 | 1,147
Schizophrenia 1,136 | 1,136
acute quadriplegic myopathy 1,133 | 1,133
astrocytoma 1,113 | 1,113
primary pancreatic ductal adenocarcinoma 1,071 | 1,071
spina bifida 1,053 | 1,053
pediatric high grade glioma 1,035 | 1,035
nasopharyngeal carcinoma 1,024 | 1,024
cutaneous lupus erythematosus 1,016 | 1,016
Intellectual disability 998 | 998
dermatomyositis 941 | 941
Atopic dermatitis 915 | 915
active Crohn's disease 882 | 882
non primary Sjogren syndrome sicca 861 | 861
gastric carcinoma 781 | 781
Epilepsy 775 | 775
acute myeloid leukemia 760 | 760
Waldenstrons macroglobulinemia 742 | 742
active ulcerative colitis 736 | 736
Liver Cirrhosis, Experimental 733 | 733
primary Sjogren syndrome 710 | 710
medulloblastoma 702 | 702
esophageal adenocarcinoma 696 | 696
Melanoma 689 | 689
progressive supranuclear palsy 656 | 656
Obesity 655 | 655
Bipolar Disorder 646 | 646
aldosterone-producing adenoma 646 | 646
Alzheimer's disease 640 | 640
Dull intelligence 634 | 634
Low intelligence 634 | 634
Mental Retardation 634 | 634
Mental deficiency 634 | 634
Poor school performance 634 | 634
Cognitive delay 596 | 596
Global developmental delay 596 | 596
Mental and motor retardation 596 | 596
Liver cancer 589 | 589
Duchenne muscular dystrophy 587 | 587
Seizures 584 | 584
Muscle hypotonia 562 | 562
pancreatic carcinoma 555 | 555
fibroadenoma 538 | 538
hepatocellular carcinoma 536 | 536
Multiple Sclerosis 527 | 527
Endometriosis 521 | 521
Short stature 514 | 514
chronic rhinosinusitis 505 | 505
autosomal dominant Emery-Dreifuss muscular dystrophy 492 | 492
Down syndrome 480 | 480
mucosa-associated lymphoid tissue lymphoma 473 | 473
Prostatic Neoplasms 472 | 472
sonic hedgehog group medulloblastoma 459 | 459
posterior fossa group A ependymoma 456 | 456
Skin cancer 451 | 451
gastric cancer 445 | 445

Tissue

Digestive Tract 127 | 17,369
Endocrine System 127 | 18,159
Female tissues 127 | 17,400
Liver and Pancreas 127 | 16,750
Skin and soft tissues 127 | 17,230
Urinary Tract 127 | 16,678
Male tissues 126 | 17,142
Blood and immune system 125 | 16,909
Respiratory system 125 | 16,393
Nervous System 123 | 16,725
Cardiovascular System 119 | 15,192

Target Family

Non-IDG 78 | 12,091
Enzyme 23 | 4,145
Kinase 9 | 634
GPCR 7 | 408
Transcription Factor 6 | 1,400
Transporter 2 | 473
Epigenetic 1 | 242
Ion Channel 1 | 344

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protocadherin-10 PCDH10 Tbio Non-IDG -1.75590 63.8 104
C-C motif chemokine 8 CCL8 Tbio Non-IDG -2.14856 127.9 298
Melanocortin-2 receptor accessory protein MRAP Tbio Non-IDG -3.60469 4145.9 102
Cytochrome P450 3A4 CYP3A4 Tclin Enzyme -3.65839 4688.0 397
Secretogranin-1 CHGB Tbio Non-IDG -2.19222 139.3 103
RIPOR family member 3 RIPOR3 Tdark Non-IDG 0.00000 56
Adipogenesis regulatory factor ADIRF Tbio Non-IDG -2.20802 160.5 48
DNA-binding protein inhibitor ID-1 ID1 Tbio Transcription Factor -2.62261 440.3 311
Inactive ubiquitin carboxyl-terminal hydrolase 53 USP53 Tdark Enzyme 0.02 1.54 61
Juxtaposed with another zinc finger protein 1 JAZF1 Tbio Non-IDG -1.61585 42.8 94