Development Level

Tbio 329 | 10,625
Tdark 72 | 7,003
Tchem 55 | 1,890
Tclin 21 | 602

Collection

Eligible Ion Channel Proteins 5 | 117
Eligible non-olfactory GPCR Proteins 2 | 145

IMPC Term

preweaning lethality, complete... 9 | 633
abnormal behavior 7 | 226
decreased body weight 7 | 174
decreased total body fat amoun... 7 | 186
increased circulating alkaline... 7 | 119
hyperactivity 6 | 108
decreased bone mineral density 5 | 126
decreased circulating glucose ... 5 | 121
decreased lean body mass 5 | 195
increased bone mineral content 5 | 92
increased lean body mass 5 | 107
increased or absent threshold ... 5 | 128
decreased body length 4 | 108
decreased bone mineral content 4 | 157
decreased circulating alanine ... 4 | 53
decreased circulating choleste... 4 | 85
decreased grip strength 4 | 123
hypoactivity 4 | 89
abnormal bone structure 3 | 131
abnormal lens morphology 3 | 73
abnormal lung morphology 3 | 15
cataract 3 | 26
decreased B cell number 3 | 30
decreased NK cell number 3 | 16
decreased T cell number 3 | 31
decreased caudal vertebrae num... 3 | 49
decreased circulating fructosa... 3 | 31
decreased circulating insulin ... 3 | 75
decreased mature B cell number 3 | 25
enlarged heart 3 | 111
increased body weight 3 | 42
increased bone mineral density 3 | 52
increased circulating sodium l... 3 | 71
increased fasted circulating g... 3 | 68
increased mean corpuscular hem... 3 | 93
increased mean corpuscular vol... 3 | 91
limb grasping 3 | 35
preweaning lethality, incomple... 3 | 260
short tibia 3 | 82
abnormal cornea morphology 2 | 24
abnormal embryo size 2 | 112
abnormal eye morphology 2 | 38
abnormal femur morphology 2 | 14
abnormal humerus morphology 2 | 11
abnormal startle reflex 2 | 14
corneal opacity 2 | 25
decreased CD8-positive, alpha-... 2 | 26
decreased circulating HDL chol... 2 | 77
decreased circulating aspartat... 2 | 27
decreased circulating calcium ... 2 | 33
decreased circulating serum al... 2 | 79
decreased circulating sodium l... 2 | 18
decreased circulating total pr... 2 | 41
decreased erythrocyte cell num... 2 | 43
decreased fasted circulating g... 2 | 49
decreased heart weight 2 | 44
decreased lumbar vertebrae num... 2 | 62
decreased monocyte cell number 2 | 28
decreased rib number 2 | 59
decreased startle reflex 2 | 48
embryonic lethality prior to t... 2 | 187
enlarged lymph nodes 2 | 27
improved glucose tolerance 2 | 56
increased circulating chloride... 2 | 43
increased effector memory CD8-... 2 | 14
increased exploration in new e... 2 | 56
increased hematocrit 2 | 36
increased sacral vertebrae num... 2 | 62
increased startle reflex 2 | 38
thrombocytopenia 2 | 46
abnormal body wall morphology 1 | 7
abnormal cranium morphology 1 | 32
abnormal heart morphology 1 | 51
abnormal locomotor activation 1 | 26
abnormal retinal pigmentation 1 | 61
abnormal rib morphology 1 | 28
abnormal skin morphology 1 | 23
abnormal testis morphology 1 | 30
abnormal thoracic vertebrae mo... 1 | 16
absent pinna reflex 1 | 21
decreased CD4-positive, alpha ... 1 | 19
decreased blood urea nitrogen ... 1 | 31
decreased circulating triglyce... 1 | 83
decreased eosinophil cell numb... 1 | 41
decreased mean corpuscular hem... 1 | 34
decreased thoracic vertebrae n... 1 | 7
female infertility 1 | 34
increased CD4-positive, CD25-p... 1 | 18
increased NK cell number 1 | 19
increased circulating HDL chol... 1 | 63
increased circulating choleste... 1 | 53
increased circulating magnesiu... 1 | 10
increased circulating triglyce... 1 | 24
increased effector memory CD4-... 1 | 15
increased eosinophil cell numb... 1 | 9
increased mean platelet volume 1 | 19
long tibia 1 | 13
prenatal lethality prior to he... 1 | 64
straub tail 1 | 26
trunk curl 1 | 15

Disease

active ulcerative colitis 477 | 477
ovarian cancer 8,492 | 8,492
osteosarcoma 7,933 | 7,933
psoriasis 6,685 | 6,685
medulloblastoma, large-cell 6,234 | 6,234
glioblastoma 5,572 | 5,572
lung cancer 4,473 | 4,473
atypical teratoid / rhabdoid tumor 4,369 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 3,289 | 3,289
malignant mesothelioma 3,163 | 3,163
Breast cancer 3,099 | 3,099
pilocytic astrocytoma 3,086 | 3,086
primitive neuroectodermal tumor 3,031 | 3,031
intraductal papillary-mucinous carcinoma (IPMC) 2,988 | 2,988
intraductal papillary-mucinous adenoma (IPMA) 2,956 | 2,956
invasive ductal carcinoma 2,950 | 2,950
oligodendroglioma 2,849 | 2,849
lung carcinoma 2,844 | 2,844
non-small cell lung cancer 2,798 | 2,798
lung adenocarcinoma 2,714 | 2,714
pediatric high grade glioma 2,712 | 2,712
ependymoma 2,514 | 2,514
Cancer 2,346 | 2,346
pancreatic cancer 2,300 | 2,300
interstitial cystitis 2,299 | 2,299
subependymal giant cell astrocytoma 2,287 | 2,287
group 3 medulloblastoma 2,254 | 2,254
astrocytic glioma 2,241 | 2,241
adult high grade glioma 2,148 | 2,148
Carcinoma 2,147 | 2,147
ulcerative colitis 2,087 | 2,087
pituitary cancer 1,972 | 1,972
Pick disease 1,893 | 1,893
group 4 medulloblastoma 1,875 | 1,875
pancreatic ductal adenocarcinoma liver metastasis 1,795 | 1,795
ductal carcinoma in situ 1,745 | 1,745
cystic fibrosis 1,670 | 1,670
diabetes mellitus 1,663 | 1,663
breast carcinoma 1,614 | 1,614
tuberculosis 1,563 | 1,563
posterior fossa group B ependymoma 1,530 | 1,530
medulloblastoma 1,524 | 1,524
posterior fossa group A ependymoma 1,511 | 1,511
astrocytoma 1,493 | 1,493
sonic hedgehog group medulloblastoma 1,482 | 1,482
colon cancer 1,475 | 1,475
adrenocortical carcinoma 1,427 | 1,427
Multiple myeloma 1,328 | 1,328
primary pancreatic ductal adenocarcinoma 1,271 | 1,271
juvenile dermatomyositis 1,189 | 1,189
Rheumatoid Arthritis 1,171 | 1,171
acute quadriplegic myopathy 1,157 | 1,157
atypical teratoid/rhabdoid tumor 1,095 | 1,095
spina bifida 1,064 | 1,064
cutaneous lupus erythematosus 1,056 | 1,056
nasopharyngeal carcinoma 1,056 | 1,056
dermatomyositis 967 | 967
Atopic dermatitis 944 | 944
active Crohn's disease 918 | 918
non primary Sjogren syndrome sicca 840 | 840
gastric carcinoma 832 | 832
primary Sjogren syndrome 789 | 789
acute myeloid leukemia 785 | 785
Waldenstrons macroglobulinemia 765 | 765
esophageal adenocarcinoma 737 | 737
tuberculosis and treatment for 6 months 686 | 686
progressive supranuclear palsy 674 | 674
aldosterone-producing adenoma 664 | 664
Alzheimer's disease 644 | 644
Obesity 616 | 616
Duchenne muscular dystrophy 602 | 602
Intellectual disability 573 | 573
pancreatic carcinoma 567 | 567
fibroadenoma 557 | 557
hepatocellular carcinoma 550 | 550
Down syndrome 548 | 548
Endometriosis 535 | 535
chronic rhinosinusitis 512 | 512
Schizophrenia 503 | 503
autosomal dominant Emery-Dreifuss muscular dystrophy 499 | 499
Multiple Sclerosis 498 | 498
mucosa-associated lymphoid tissue lymphoma 480 | 480
Prostatic Neoplasms 471 | 471
IGA Glomerulonephritis 454 | 454
gastric cancer 436 | 436
Amyotrophic Lateral Sclerosis 432 | 432
non-small cell lung carcinoma 413 | 413
Mammary Neoplasms 410 | 410
inflammatory breast cancer 404 | 404
Kidney disease 397 | 397
Neurodegenerative disease 383 | 383
sarcoidosis 368 | 368
Parkinson's disease 364 | 364
Asthma 349 | 349
glioblastoma multiforme 347 | 347
Epilepsy 346 | 346
Polycystic Ovary Syndrome 335 | 335
nephrosclerosis 329 | 329
tuberculosis and treatment for 3 months 327 | 327
Autistic Disorder 320 | 320

Tissue

Digestive Tract 470 | 18,473
Urinary Tract 469 | 18,444
Cardiovascular System 468 | 17,958
Endocrine System 468 | 18,512
Female tissues 468 | 18,647
Liver and Pancreas 467 | 18,136
Nervous System 467 | 18,561
Male tissues 466 | 17,969
Blood and immune system 465 | 17,995
Respiratory system 465 | 17,484
Skin and soft tissues 464 | 18,115

Target Family

Non-IDG 264 | 11,969
Enzyme 112 | 4,146
Transcription Factor 32 | 1,400
Transporter 31 | 473
Kinase 15 | 634
Ion Channel 13 | 341
GPCR 7 | 408
Nuclear Receptor 2 | 48
Epigenetic 1 | 242

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Homeobox protein Hox-D10 HOXD10 Tbio Transcription Factor -1.76497 45.4 166
Putative uncharacterized protein encoded by LINC00467 LINC00467 Tdark Non-IDG 0.00000 0
Protein C-ets-2 ETS2 Tbio Transcription Factor -2.39443 244.9 192
Zinc finger protein ZFPM2 ZFPM2 Tbio Transcription Factor -1.75745 57.5 78
Protein Hook homolog 3 HOOK3 Tbio Non-IDG -1.18684 0.00000 55
Short-chain dehydrogenase/reductase family 42E member 1 SDR42E1 Tdark Enzyme 0.00000 11
Guanine nucleotide-binding protein subunit alpha-15 GNA15 Tbio Non-IDG -2.74618 475.0 155
Probable global transcription activator SNF2L1 SMARCA1 Tbio Non-IDG -2.18842 137.5 94
Ecto-ADP-ribosyltransferase 3 ART3 Tbio Enzyme -1.29743 20.5 266
Inactive cytidine monophosphate-N-acetylneuraminic acid hydroxylase CMAHP Tbio Enzyme -1.70218 50.2 0