Development Level

Tbio 532 | 11,445
Tdark 103 | 6,588
Tchem 100 | 1,598
Tclin 29 | 613

Collection

RFA-RM-18-021 9 | 328
Ion Channel: IDG Consortium (T... 6 | 99
GPCR: IDG Consortium (Targets) 2 | 126
GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

preweaning lethality, complete... 26 | 979
preweaning lethality, incomple... 24 | 499
decreased total body fat amoun... 15 | 207
decreased vertical activity 13 | 208
increased bone mineral content 11 | 108
increased lean body mass 11 | 172
abnormal behavior 10 | 298
hyperactivity 10 | 148
increased circulating alkaline... 10 | 122
decreased body weight 9 | 161
decreased bone mineral content 9 | 151
decreased bone mineral density 9 | 126
enlarged heart 9 | 210
abnormal heart morphology 8 | 162
decreased grip strength 8 | 116
abnormal bone structure 7 | 187
cataract 7 | 92
increased bone mineral density 7 | 72
abnormal embryo size 6 | 220
decreased body length 6 | 101
hypoactivity 6 | 132
thrombocytopenia 6 | 56
abnormal lens morphology 5 | 81
decreased blood urea nitrogen ... 5 | 51
decreased circulating glucose ... 5 | 126
decreased circulating insulin ... 5 | 76
decreased heart weight 5 | 27
decreased startle reflex 5 | 75
embryonic lethality prior to t... 5 | 278
enlarged lymph nodes 5 | 37
increased mean corpuscular hem... 5 | 96
increased mean corpuscular hem... 5 | 36
increased startle reflex 5 | 112
abnormal behavioral response t... 4 | 66
abnormal gait 4 | 69
decreased circulating HDL chol... 4 | 68
decreased circulating alanine ... 4 | 47
decreased circulating calcium ... 4 | 36
decreased fasted circulating g... 4 | 65
decreased lean body mass 4 | 135
decreased lymphocyte cell numb... 4 | 83
decreased mean corpuscular vol... 4 | 79
decreased red blood cell distr... 4 | 41
increased body weight 4 | 25
increased circulating HDL chol... 4 | 80
increased circulating sodium l... 4 | 71
increased fasted circulating g... 4 | 76
increased mean corpuscular vol... 4 | 92
increased total body fat amoun... 4 | 134
limb grasping 4 | 41
abnormal femur morphology 3 | 14
abnormal lung morphology 3 | 26
abnormal retina morphology 3 | 71
abnormal seminal vesicle morph... 3 | 114
corneal opacity 3 | 32
decreased circulating choleste... 3 | 93
decreased circulating serum al... 3 | 82
decreased circulating total pr... 3 | 49
decreased circulating triglyce... 3 | 79
decreased hemoglobin content 3 | 68
decreased large unstained cell... 3 | 11
decreased leukocyte cell numbe... 3 | 73
decreased prepulse inhibition 3 | 82
improved glucose tolerance 3 | 79
increased circulating choleste... 3 | 66
increased circulating phosphat... 3 | 26
increased monocyte cell number 3 | 63
increased or absent threshold ... 3 | 101
abnormal body wall morphology 2 | 9
abnormal cornea morphology 2 | 31
abnormal cranium morphology 2 | 36
abnormal epididymis morphology 2 | 42
abnormal eye morphology 2 | 68
abnormal head morphology 2 | 10
abnormal liver morphology 2 | 17
abnormal retinal vasculature m... 2 | 27
abnormal sleep behavior 2 | 70
abnormal spleen morphology 2 | 55
abnormal testis morphology 2 | 43
abnormal vertebrae morphology 2 | 18
decreased circulating aspartat... 2 | 34
decreased circulating bilirubi... 2 | 19
decreased circulating sodium l... 2 | 22
decreased hematocrit 2 | 46
enlarged spleen 2 | 41
impaired glucose tolerance 2 | 75
impaired pupillary reflex 2 | 26
impaired righting response 2 | 26
increased body length 2 | 32
increased circulating amylase ... 2 | 25
increased circulating fructosa... 2 | 13
increased circulating serum al... 2 | 22
increased circulating triglyce... 2 | 42
increased heart weight 2 | 62
long tibia 2 | 25
male infertility 2 | 123
prenatal lethality prior to he... 2 | 87
small superior vagus ganglion 2 | 74
small testis 2 | 58
tremors 2 | 39

Disease

active ulcerative colitis 764 | 764
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Digestive Tract 750 | 17,369
Female tissues 746 | 17,400
Endocrine System 745 | 18,159
Skin and soft tissues 743 | 17,230
Male tissues 740 | 17,142
Urinary Tract 737 | 16,678
Liver and Pancreas 736 | 16,750
Blood and immune system 730 | 16,909
Respiratory system 724 | 16,393
Nervous System 723 | 16,725
Cardiovascular System 664 | 15,192

Target Family

Non-IDG 406 | 12,091
Enzyme 203 | 4,145
Transporter 51 | 473
Transcription Factor 45 | 1,400
Kinase 28 | 634
Ion Channel 16 | 344
GPCR 10 | 408
Nuclear Receptor 3 | 48
Epigenetic 1 | 242
TF/Epigenetic 1 | 38

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Inactive cytidine monophosphate-N-acetylneuraminic acid hydroxylase CMAHP Tbio Enzyme -1.76743 57.3 0
Probable global transcription activator SNF2L1 SMARCA1 Tbio Non-IDG -2.20560 145.6 116
Protein S100-A11 S100A11 Tbio Non-IDG -2.01412 110.0 311
Rab-3A-interacting protein RAB3IP Tbio Non-IDG -1.03500 11.6 89
Redox-regulatory protein FAM213A FAM213A Tbio Non-IDG -1.51277 30.6 63
Sorcin SRI Tbio Non-IDG -2.69915 481.5 119
Four and a half LIM domains protein 1 FHL1 Tbio Non-IDG -2.46134 291.4 312
Choline transporter-like protein 1 SLC44A1 Tbio Transporter -1.60796 43.9 212
DNA damage-inducible transcript 4 protein DDIT4 Tbio Non-IDG -2.11497 150.3 231
Proline-rich transmembrane protein 1 PRRT1 Tbio Non-IDG -1.33375 18.2 68