Development Level

Tbio 592 | 11,445
Tchem 97 | 1,598
Tdark 45 | 6,588
Tclin 31 | 613

Collection

RFA-RM-18-021 4 | 328
Kinase: IDG Consortium (Target... 3 | 125
GPCR: IDG Consortium (Complete... 1 | 25
GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

preweaning lethality, complete... 69 | 979
preweaning lethality, incomple... 26 | 499
embryonic lethality prior to o... 23 | 239
embryonic lethality prior to t... 19 | 278
decreased total body fat amoun... 12 | 207
abnormal embryo size 11 | 220
abnormal behavior 9 | 298
decreased body weight 9 | 161
cataract 8 | 92
hypoactivity 8 | 132
abnormal bone structure 7 | 187
decreased leukocyte cell numbe... 7 | 73
increased lean body mass 7 | 172
abnormal lens morphology 6 | 81
decreased circulating alanine ... 6 | 47
decreased grip strength 6 | 116
thrombocytopenia 6 | 56
increased hemoglobin content 5 | 45
increased mean corpuscular hem... 5 | 36
increased or absent threshold ... 5 | 101
increased startle reflex 5 | 112
abnormal heart morphology 4 | 162
abnormal retina morphology 4 | 71
decreased circulating serum al... 4 | 82
decreased mean corpuscular hem... 4 | 31
embryonic growth retardation 4 | 106
increased body weight 4 | 25
increased bone mineral density 4 | 72
increased circulating alkaline... 4 | 122
increased circulating sodium l... 4 | 71
increased heart weight 4 | 62
increased mean corpuscular hem... 4 | 96
increased total body fat amoun... 4 | 134
male infertility 4 | 123
abnormal coat-hair pigmentatio... 3 | 64
abnormal gait 3 | 69
abnormal maxilla morphology 3 | 17
abnormal neural tube closure 3 | 46
decreased bone mineral density 3 | 126
decreased circulating aspartat... 3 | 34
decreased circulating choleste... 3 | 93
decreased circulating glucose ... 3 | 126
decreased erythrocyte cell num... 3 | 62
decreased lymphocyte cell numb... 3 | 83
decreased mean corpuscular hem... 3 | 50
decreased mean corpuscular vol... 3 | 79
decreased neutrophil cell numb... 3 | 42
decreased prepulse inhibition 3 | 82
decreased startle reflex 3 | 75
decreased vertical activity 3 | 208
female infertility 3 | 60
hyperactivity 3 | 148
increased blood urea nitrogen ... 3 | 48
increased bone mineral content 3 | 108
increased circulating HDL chol... 3 | 80
increased circulating chloride... 3 | 41
increased grip strength 3 | 41
increased mean corpuscular vol... 3 | 92
increased neutrophil cell numb... 3 | 46
increased prepulse inhibition 3 | 32
abnormal coat appearance 2 | 31
abnormal cranium morphology 2 | 36
abnormal kidney morphology 2 | 65
abnormal sleep behavior 2 | 70
abnormal snout morphology 2 | 23
abnormal testis morphology 2 | 43
abnormal vitreous body morphol... 2 | 10
brachydactyly 2 | 19
decreased body length 2 | 101
decreased bone mineral content 2 | 151
decreased caudal vertebrae num... 2 | 53
decreased circulating calcium ... 2 | 36
decreased circulating chloride... 2 | 30
decreased circulating creatini... 2 | 39
decreased circulating magnesiu... 2 | 13
decreased circulating potassiu... 2 | 20
decreased circulating triglyce... 2 | 79
decreased hemoglobin content 2 | 68
decreased lactate dehydrogenas... 2 | 16
decreased lean body mass 2 | 135
decreased red blood cell distr... 2 | 41
decreased total retina thickne... 2 | 17
enlarged heart 2 | 210
enlarged lymph nodes 2 | 37
impaired glucose tolerance 2 | 75
increased body length 2 | 32
increased circulating amylase ... 2 | 25
increased circulating bilirubi... 2 | 16
increased circulating choleste... 2 | 66
increased circulating potassiu... 2 | 29
increased fasted circulating g... 2 | 76
increased hematocrit 2 | 46
limb grasping 2 | 41
microphthalmia 2 | 26
prenatal lethality prior to he... 2 | 87
shortened RR interval 2 | 17
small adrenal glands 2 | 16
small spleen 2 | 19
small testis 2 | 58
syndactyly 2 | 23

Disease

Waldenstrons macroglobulinemia 765 | 765
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Digestive Tract 762 | 17,369
Endocrine System 762 | 18,159
Female tissues 762 | 17,400
Blood and immune system 761 | 16,909
Liver and Pancreas 761 | 16,750
Respiratory system 761 | 16,393
Skin and soft tissues 761 | 17,230
Male tissues 759 | 17,142
Urinary Tract 759 | 16,678
Cardiovascular System 756 | 15,192
Nervous System 755 | 16,725

Target Family

Non-IDG 449 | 12,091
Enzyme 211 | 4,145
Transcription Factor 34 | 1,400
Kinase 32 | 634
Epigenetic 15 | 242
Transporter 12 | 473
GPCR 7 | 408
Ion Channel 2 | 344
Nuclear Receptor 2 | 48
TF/Epigenetic 1 | 38

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Uncharacterized protein KIAA1551 KIAA1551 Tdark Non-IDG -0.49946 2.76 22
60S ribosomal protein L3 RPL3 Tbio Non-IDG -2.02901 103.9 190
Heterogeneous nuclear ribonucleoprotein H3 HNRNPH3 Tbio Non-IDG -1.80776 63.4 80
Sorcin SRI Tbio Non-IDG -2.69915 481.5 119
SAFB-like transcription modulator SLTM Tdark Non-IDG -0.51977 2.83 111
Heterogeneous nuclear ribonucleoprotein M HNRNPM Tbio Non-IDG -1.64443 45.9 331
U3 small nucleolar RNA-associated protein 18 homolog UTP18 Tdark Non-IDG -0.50488 2.92 52
Tetratricopeptide repeat protein 19, mitochondrial TTC19 Tbio Non-IDG -0.95371 10.6 38
Sodium-coupled neutral amino acid transporter 2 SLC38A2 Tbio Transporter -1.98482 96.5 91
T-complex protein 1 subunit zeta CCT6A Tbio Non-IDG -1.39880 26.2 90