Development Level

Tbio 185 | 11,651
Tchem 92 | 1,388
Tclin 33 | 612
Tdark 9 | 6,593

IMPC Phenotype

preweaning lethality, complete... 21 | 979
preweaning lethality, incomple... 11 | 499
decreased total body fat amoun... 8 | 207
embryonic lethality prior to t... 8 | 278
increased circulating HDL chol... 7 | 80
increased circulating alkaline... 7 | 122
increased total body fat amoun... 7 | 134
decreased fasted circulating g... 5 | 65
decreased lean body mass 5 | 135
enlarged heart 5 | 210
increased circulating choleste... 5 | 66
abnormal behavior 4 | 298
abnormal bone structure 4 | 187
abnormal embryo size 4 | 220
decreased mean corpuscular vol... 4 | 79
embryonic lethality prior to o... 4 | 239
impaired glucose tolerance 4 | 75
increased lean body mass 4 | 172
increased mean corpuscular vol... 4 | 92
tremors 4 | 39
abnormal coat- hair morphology 3 | 19
abnormal gait 3 | 69
abnormal heart morphology 3 | 162
abnormal retina morphology 3 | 71
cataract 3 | 92
decreased body length 3 | 101
decreased circulating HDL chol... 3 | 68
decreased circulating choleste... 3 | 93
decreased circulating insulin ... 3 | 76
decreased grip strength 3 | 116
decreased startle reflex 3 | 75
decreased vertical activity 3 | 208
hypoactivity 3 | 132
increased circulating chloride... 3 | 41
increased circulating total pr... 3 | 28
increased fasted circulating g... 3 | 76
increased red blood cell distr... 3 | 34
increased startle reflex 3 | 112
short tibia 3 | 97
abnormal bone mineralization 2 | 38
abnormal femur morphology 2 | 14
abnormal forebrain development 2 | 20
abnormal hindbrain development 2 | 16
abnormal lens morphology 2 | 81
abnormal locomotor behavior 2 | 24
abnormal neural tube closure 2 | 46
abnormal retinal blood vessel ... 2 | 26
abnormal sleep behavior 2 | 70
abnormal snout morphology 2 | 23
decreased body weight 2 | 161
decreased bone mineral content 2 | 151
decreased circulating alanine ... 2 | 47
decreased circulating alkaline... 2 | 46
decreased circulating free fat... 2 | 31
decreased circulating triglyce... 2 | 79
decreased erythrocyte cell num... 2 | 62
decreased heart left ventricle... 2 | 28
decreased lymphocyte cell numb... 2 | 83
decreased mean corpuscular hem... 2 | 31
decreased neutrophil cell numb... 2 | 42
decreased pulmonary respirator... 2 | 5
decreased red blood cell distr... 2 | 41
enlarged stomach 2 | 2
improved glucose tolerance 2 | 79
increased body length 2 | 32
increased circulating amylase ... 2 | 25
increased circulating calcium ... 2 | 34
increased circulating iron lev... 2 | 30
increased circulating phosphat... 2 | 26
increased circulating triglyce... 2 | 42
increased grip strength 2 | 41
increased lymphocyte cell numb... 2 | 32
increased mean corpuscular hem... 2 | 96
increased monocyte cell number 2 | 63
male infertility 2 | 123
prenatal lethality prior to he... 2 | 87
small thymus 2 | 16
thin ventricular wall 2 | 24
thrombocytopenia 2 | 56
abnormal epididymis morphology 1 | 42
abnormal head morphology 1 | 10
abnormal heart left ventricle ... 1 | 16
abnormal liver morphology 1 | 17
abnormal lung morphology 1 | 26
abnormal retinal vasculature m... 1 | 27
convulsive seizures 1 | 13
decreased IgG1 level 1 | 8
decreased T cell number 1 | 15
decreased circulating amylase ... 1 | 28
decreased circulating calcium ... 1 | 36
decreased circulating iron lev... 1 | 32
decreased hematocrit 1 | 46
increased bone mineral density 1 | 72
increased circulating bilirubi... 1 | 16
increased circulating serum al... 1 | 22
increased eosinophil cell numb... 1 | 11
increased heart weight 1 | 62
increased hemoglobin content 1 | 45
persistence of hyaloid vascula... 1 | 33
vertebral fusion 1 | 23

Disease

Vascular disease 319 | 319
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Digestive Tract 309 | 17,369
Endocrine System 307 | 18,159
Female tissues 307 | 17,400
Skin and soft tissues 306 | 17,230
Liver and Pancreas 303 | 16,750
Urinary Tract 302 | 16,678
Male tissues 300 | 17,142
Blood and immune system 299 | 16,909
Respiratory system 296 | 16,393
Nervous System 293 | 16,725
Cardiovascular System 279 | 15,192

Target Family

Non-IDG 155 | 12,091
Enzyme 77 | 4,145
Transcription Factor 25 | 1,400
Kinase 23 | 634
GPCR 14 | 408
Ion Channel 12 | 344
Transporter 7 | 473
Epigenetic 3 | 242
Nuclear Receptor 3 | 48

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Dual specificity protein phosphatase 1 DUSP1 Tchem Enzyme -2.88260 810.9 388
ATP-binding cassette sub-family A member 1 ABCA1 Tclin Transporter -3.15111 1451.8 388
Integrin alpha-2 ITGA2 Tbio Non-IDG -2.58423 335.9 895
Thrombospondin-1 THBS1 Tbio Non-IDG -3.06622 1281.6 504
Inactive caspase-12 CASP12 Tbio Enzyme -2.64252 415.1 429
TSC22 domain family protein 1 TSC22D1 Tbio Transcription Factor -1.54599 46.0 300
Estrogen receptor ESR1 Tclin Nuclear Receptor -4.00480 8421.6 2610