Development Level

Tbio 109 | 11,651
Tclin 26 | 612
Tchem 22 | 1,388

Collection

Kinase: IDG Consortium (Target... 1 | 125
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 17 | 979
embryonic lethality prior to t... 6 | 278
preweaning lethality, incomple... 4 | 499
decreased mean corpuscular vol... 3 | 79
increased startle reflex 3 | 112
abnormal behavior 2 | 298
abnormal bone structure 2 | 187
abnormal gait 2 | 69
decreased bone mineral content 2 | 151
decreased grip strength 2 | 116
decreased lean body mass 2 | 135
embryonic lethality prior to o... 2 | 239
enlarged heart 2 | 210
enlarged urinary bladder 2 | 8
hypoactivity 2 | 132
impaired glucose tolerance 2 | 75
increased leukocyte cell numbe... 2 | 47
increased lymphocyte cell numb... 2 | 32
increased thermal nociceptive ... 2 | 9
increased total body fat amoun... 2 | 134
prenatal lethality 2 | 28
prenatal lethality prior to he... 2 | 87
small testis 2 | 58
tremors 2 | 39
abnormal cornea morphology 1 | 31
abnormal embryo size 1 | 220
abnormal eye anterior chamber ... 1 | 9
abnormal eye morphology 1 | 68
abnormal forebrain development 1 | 20
abnormal heart morphology 1 | 162
abnormal hindbrain development 1 | 16
abnormal joint morphology 1 | 23
abnormal kidney morphology 1 | 65
abnormal limb bud morphology 1 | 17
abnormal liver size 1 | 5
abnormal lung morphology 1 | 26
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal optic disc morphology 1 | 10
abnormal placenta size 1 | 20
abnormal retina morphology 1 | 71
abnormal skin condition 1 | 6
abnormal skin morphology 1 | 50
abnormal snout morphology 1 | 23
abnormal spleen morphology 1 | 55
abnormal stomach morphology 1 | 10
abnormal tooth morphology 1 | 24
abnormal urinary bladder morph... 1 | 11
aorta dilation 1 | 3
brachydactyly 1 | 19
cataract 1 | 92
corneal opacity 1 | 32
cystolithiasis 1 | 3
decreased body weight 1 | 161
decreased circulating alkaline... 1 | 46
decreased circulating amylase ... 1 | 28
decreased circulating creatini... 1 | 39
decreased circulating sodium l... 1 | 22
decreased fasted circulating g... 1 | 65
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 31
decreased neutrophil cell numb... 1 | 42
decreased red blood cell distr... 1 | 41
decreased spleen weight 1 | 10
decreased thermal nociceptive ... 1 | 2
decreased total body fat amoun... 1 | 207
embryonic growth retardation 1 | 106
enlarged kidney 1 | 14
enlarged lymph nodes 1 | 37
enlarged spleen 1 | 41
increased body weight 1 | 25
increased circulating alkaline... 1 | 122
increased circulating free fat... 1 | 20
increased circulating triglyce... 1 | 42
increased fasted circulating g... 1 | 76
increased heart weight 1 | 62
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 36
increased neutrophil cell numb... 1 | 46
increased respiratory quotient 1 | 2
increased spleen weight 1 | 10
irregularly shaped pupil 1 | 7
limb grasping 1 | 41
male infertility 1 | 123
pale liver 1 | 6
pale yolk sac 1 | 25
pallor 1 | 34
persistence of hyaloid vascula... 1 | 33
polycystic kidney 1 | 15
prolonged QT interval 1 | 38
shortened QT interval 1 | 4
small kidney 1 | 16
syndactyly 1 | 23

Disease

Variable expressivity 157 | 157
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Endocrine System 156 | 18,159
Digestive Tract 155 | 17,369
Skin and soft tissues 152 | 17,230
Female tissues 151 | 17,400
Urinary Tract 151 | 16,678
Liver and Pancreas 150 | 16,750
Male tissues 150 | 17,142
Nervous System 150 | 16,725
Blood and immune system 147 | 16,909
Respiratory system 144 | 16,393
Cardiovascular System 131 | 15,192

Target Family

Non-IDG 66 | 12,091
Enzyme 53 | 4,145
Transcription Factor 16 | 1,400
Ion Channel 11 | 344
Transporter 5 | 473
Kinase 4 | 634
Epigenetic 2 | 242

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Atlastin-1 ATL1 Tbio Non-IDG -2.07795 119.7 164
Myosin-2 MYH2 Tbio Non-IDG -2.14128 114.9 63
Gap junction beta-6 protein GJB6 Tbio Non-IDG -2.99235 908.9 170
Sodium channel protein type 2 subunit alpha SCN2A Tclin Ion Channel -3.11580 1268.8 107
Protein O-mannosyl-transferase 2 POMT2 Tbio Enzyme -1.48456 31.6 104
Mitochondrial pyruvate carrier 1 MPC1 Tbio Non-IDG -1.77095 56.4 96
Mannose-1-phosphate guanyltransferase beta GMPPB Tbio Enzyme -1.17283 16.0 118
Protein patched homolog 1 PTCH1 Tbio Non-IDG -3.04637 1057.4 452
Platelet glycoprotein VI GP6 Tbio Non-IDG -2.73714 584.5 201
Acid ceramidase ASAH1 Tchem Enzyme -2.94716 848.0 203