Development Level

Tbio 168 | 11,651
Tdark 50 | 6,593
Tchem 34 | 1,388
Tclin 20 | 612

Collection

RFA-RM-18-021 2 | 328
GPCR: IDG Consortium (Complete... 1 | 25
Ion Channel: IDG Consortium (T... 1 | 99
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 18 | 979
preweaning lethality, incomple... 11 | 499
decreased total body fat amoun... 8 | 207
abnormal behavior 7 | 298
decreased vertical activity 6 | 208
enlarged heart 6 | 210
abnormal seminal vesicle morph... 5 | 114
decreased prepulse inhibition 4 | 82
hypoactivity 4 | 132
improved glucose tolerance 4 | 79
short tibia 4 | 97
abnormal bone structure 3 | 187
abnormal eye morphology 3 | 68
abnormal heart morphology 3 | 162
abnormal retina morphology 3 | 71
cataract 3 | 92
decreased circulating alanine ... 3 | 47
decreased circulating choleste... 3 | 93
decreased circulating fructosa... 3 | 30
decreased circulating glucose ... 3 | 126
decreased fasted circulating g... 3 | 65
decreased lean body mass 3 | 135
decreased mean corpuscular vol... 3 | 79
decreased startle reflex 3 | 75
enlarged kidney 3 | 14
hyperactivity 3 | 148
increased bone mineral content 3 | 108
increased bone mineral density 3 | 72
increased circulating HDL chol... 3 | 80
increased fasted circulating g... 3 | 76
increased lean body mass 3 | 172
increased or absent threshold ... 3 | 101
increased red blood cell distr... 3 | 34
increased startle reflex 3 | 112
increased total body fat amoun... 3 | 134
abnormal coat-hair pigmentatio... 2 | 64
abnormal embryo size 2 | 220
abnormal gait 2 | 69
abnormal kidney morphology 2 | 65
abnormal lens morphology 2 | 81
abnormal lung morphology 2 | 26
abnormal testis morphology 2 | 43
decreased body length 2 | 101
decreased body weight 2 | 161
decreased bone mineral content 2 | 151
decreased circulating HDL chol... 2 | 68
decreased circulating LDL chol... 2 | 38
decreased circulating aspartat... 2 | 34
decreased circulating insulin ... 2 | 76
decreased circulating serum al... 2 | 82
decreased heart left ventricle... 2 | 28
decreased lactate dehydrogenas... 2 | 16
decreased lymphocyte cell numb... 2 | 83
decreased red blood cell distr... 2 | 41
decreased respiratory quotient 2 | 16
embryonic lethality prior to t... 2 | 278
enlarged lymph nodes 2 | 37
impaired glucose tolerance 2 | 75
increased blood urea nitrogen ... 2 | 48
increased circulating aspartat... 2 | 15
increased circulating choleste... 2 | 66
increased erythrocyte cell num... 2 | 39
increased hemoglobin content 2 | 45
increased leukocyte cell numbe... 2 | 47
increased mean platelet volume 2 | 45
increased monocyte cell number 2 | 63
prenatal lethality 2 | 28
prenatal lethality prior to he... 2 | 87
prolonged ST segment 2 | 36
small testis 2 | 58
thin ventricular wall 2 | 24
abnormal behavioral response t... 1 | 66
abnormal cranium morphology 1 | 36
abnormal pancreas morphology 1 | 13
abnormal retinal vasculature m... 1 | 27
abnormal sleep behavior 1 | 70
abnormal spleen morphology 1 | 55
abnormal vibrissa morphology 1 | 25
cardiovascular system phenotyp... 1 | 36
convulsive seizures 1 | 13
decreased bone mineral density 1 | 126
decreased circulating calcium ... 1 | 36
decreased circulating iron lev... 1 | 32
decreased eosinophil cell numb... 1 | 24
decreased hematocrit 1 | 46
decreased mean corpuscular hem... 1 | 31
increased anti-nuclear antigen... 1 | 19
increased body weight 1 | 25
increased circulating alkaline... 1 | 122
increased circulating amylase ... 1 | 25
increased circulating fructosa... 1 | 13
increased circulating lipase l... 1 | 3
increased circulating potassiu... 1 | 29
increased circulating serum al... 1 | 22
increased circulating total pr... 1 | 28
increased heart weight 1 | 62
increased hematocrit 1 | 46
increased mean corpuscular vol... 1 | 92
persistence of hyaloid vascula... 1 | 33
thrombocytosis 1 | 27

Disease

Type 2 diabetes mellitus 272 | 272
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Endocrine System 266 | 18,159
Digestive Tract 258 | 17,369
Female tissues 256 | 17,400
Skin and soft tissues 256 | 17,230
Male tissues 255 | 17,142
Nervous System 251 | 16,725
Liver and Pancreas 250 | 16,750
Blood and immune system 249 | 16,909
Urinary Tract 249 | 16,678
Respiratory system 240 | 16,393
Cardiovascular System 224 | 15,192

Target Family

Non-IDG 138 | 12,091
Enzyme 62 | 4,145
Transcription Factor 24 | 1,400
Kinase 12 | 634
Ion Channel 11 | 344
Transporter 11 | 473
GPCR 8 | 408
Nuclear Receptor 3 | 48
Epigenetic 2 | 242
TF/Epigenetic 1 | 38

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
ATP-binding cassette sub-family A member 1 ABCA1 Tclin Transporter -3.15111 1451.8 388
Alpha-ketoglutarate-dependent dioxygenase FTO FTO Tbio Enzyme -3.13021 1342.0 318
Desmoglein-3 DSG3 Tbio Non-IDG -2.57795 402.0 381
Collagen and calcium-binding EGF domain-containing protein 1 CCBE1 Tbio Non-IDG -1.27652 20.3 165
Alkaline phosphatase, placental type ALPP Tbio Enzyme -2.71952 511.2 929
Fat storage-inducing transmembrane protein 2 FITM2 Tdark Non-IDG -1.27967 17.3 2
Transmembrane protein FAM155A FAM155A Tdark Non-IDG 0.19 0.58 69
Tyrosine-protein kinase SYK SYK Tchem Kinase -3.14835 1437.4 1136
Voltage-dependent calcium channel gamma-2 subunit CACNG2 Tbio Ion Channel -1.92203 89.6 173
Thyroid adenoma-associated protein THADA Tbio Non-IDG -1.52487 33.2 60