Development Level

Tbio 106 | 10,625
Tdark 41 | 7,003
Tchem 28 | 1,890
Tclin 17 | 602

Collection

GPCR: IDG Consortium (Complete/Control) 1 | 26

IMPC Phenotype

preweaning lethality, complete... 11 | 633
preweaning lethality, incomple... 7 | 260
abnormal retina morphology 4 | 100
decreased circulating fructosa... 4 | 31
decreased total body fat amoun... 4 | 186
abnormal retinal pigmentation 3 | 61
decreased body weight 3 | 174
decreased fasted circulating g... 3 | 49
decreased lean body mass 3 | 195
increased bone mineral content 3 | 92
increased circulating aspartat... 3 | 17
increased lean body mass 3 | 107
abnormal behavior 2 | 226
abnormal lens morphology 2 | 73
abnormal seminal vesicle morph... 2 | 47
abnormal testis morphology 2 | 30
decreased circulating LDL chol... 2 | 37
decreased circulating alanine ... 2 | 53
decreased circulating aspartat... 2 | 27
decreased circulating glucose ... 2 | 121
decreased grip strength 2 | 123
decreased startle reflex 2 | 48
hyperactivity 2 | 108
impaired glucose tolerance 2 | 52
improved glucose tolerance 2 | 56
increased circulating alkaline... 2 | 119
increased leukocyte cell numbe... 2 | 37
increased red blood cell distr... 2 | 21
increased startle reflex 2 | 38
prenatal lethality prior to he... 2 | 64
small testis 2 | 37
abnormal coat appearance 1 | 25
abnormal coat-hair pigmentatio... 1 | 54
abnormal cranium morphology 1 | 32
abnormal embryo size 1 | 112
abnormal gait 1 | 51
abnormal heart left ventricle ... 1 | 20
abnormal heart morphology 1 | 51
abnormal lung morphology 1 | 15
abnormal lymph node morphology 1 | 3
abnormal retinal vasculature m... 1 | 15
abnormal startle reflex 1 | 14
abnormal vertebrae morphology 1 | 14
cardiovascular system phenotyp... 1 | 35
convulsive seizures 1 | 11
decreased CD4-positive, CD25-p... 1 | 24
decreased KLRG1-positive NK ce... 1 | 9
decreased Ly6C low monocyte nu... 1 | 23
decreased basophil cell number 1 | 11
decreased body length 1 | 108
decreased bone mineral content 1 | 157
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 49
decreased circulating iron lev... 1 | 25
decreased circulating phosphat... 1 | 15
decreased circulating serum al... 1 | 79
decreased circulating sodium l... 1 | 18
decreased eosinophil cell numb... 1 | 41
decreased gamma-delta T cell n... 1 | 18
decreased heart rate 1 | 10
decreased heart weight 1 | 44
decreased mean corpuscular hem... 1 | 19
decreased mean corpuscular vol... 1 | 50
decreased prepulse inhibition 1 | 52
embryonic lethality prior to t... 1 | 187
enlarged lymph nodes 1 | 27
hypoactivity 1 | 89
increased B cell number 1 | 23
increased CD4-positive NK T ce... 1 | 3
increased CD4-positive, CD25-p... 1 | 18
increased Ly6C high monocyte n... 1 | 12
increased NK T cell number 1 | 11
increased NK cell number 1 | 19
increased T cell number 1 | 15
increased blood urea nitrogen ... 1 | 44
increased body weight 1 | 42
increased bone mineral density 1 | 52
increased caudal vertebrae num... 1 | 8
increased circulating alanine ... 1 | 11
increased circulating amylase ... 1 | 13
increased circulating calcium ... 1 | 32
increased circulating choleste... 1 | 53
increased circulating fructosa... 1 | 11
increased circulating potassiu... 1 | 31
increased circulating total pr... 1 | 20
increased erythrocyte cell num... 1 | 26
increased gamma-delta T cell n... 1 | 16
increased grip strength 1 | 83
increased heart weight 1 | 37
increased hemoglobin content 1 | 45
increased mean corpuscular vol... 1 | 91
increased memory-marker CD4-po... 1 | 3
increased or absent threshold ... 1 | 128
increased respiratory quotient 1 | 12
increased total body fat amoun... 1 | 57
oligodactyly 1 | 14
persistence of hyaloid vascula... 1 | 22
prenatal lethality 1 | 16
straub tail 1 | 26
thrombocytosis 1 | 23

Disease

Type 2 diabetes mellitus 192 | 192
ovarian cancer 8,491 | 8,491
osteosarcoma 7,933 | 7,933
psoriasis 6,685 | 6,685
medulloblastoma, large-cell 6,234 | 6,234
glioblastoma 5,572 | 5,572
lung cancer 4,473 | 4,473
atypical teratoid / rhabdoid tumor 4,369 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 3,289 | 3,289
malignant mesothelioma 3,163 | 3,163
Breast cancer 3,098 | 3,098
pilocytic astrocytoma 3,086 | 3,086
primitive neuroectodermal tumor 3,031 | 3,031
intraductal papillary-mucinous carcinoma (IPMC) 2,988 | 2,988
intraductal papillary-mucinous adenoma (IPMA) 2,956 | 2,956
invasive ductal carcinoma 2,950 | 2,950
oligodendroglioma 2,849 | 2,849
lung carcinoma 2,844 | 2,844
non-small cell lung cancer 2,798 | 2,798
lung adenocarcinoma 2,714 | 2,714
pediatric high grade glioma 2,712 | 2,712
ependymoma 2,514 | 2,514
Cancer 2,346 | 2,346
pancreatic cancer 2,300 | 2,300
interstitial cystitis 2,299 | 2,299
subependymal giant cell astrocytoma 2,287 | 2,287
group 3 medulloblastoma 2,254 | 2,254
astrocytic glioma 2,241 | 2,241
adult high grade glioma 2,148 | 2,148
Carcinoma 2,147 | 2,147
ulcerative colitis 2,087 | 2,087
pituitary cancer 1,972 | 1,972
Pick disease 1,893 | 1,893
group 4 medulloblastoma 1,875 | 1,875
pancreatic ductal adenocarcinoma liver metastasis 1,795 | 1,795
ductal carcinoma in situ 1,745 | 1,745
cystic fibrosis 1,670 | 1,670
diabetes mellitus 1,663 | 1,663
breast carcinoma 1,614 | 1,614
tuberculosis 1,563 | 1,563
posterior fossa group B ependymoma 1,530 | 1,530
medulloblastoma 1,524 | 1,524
posterior fossa group A ependymoma 1,511 | 1,511
astrocytoma 1,493 | 1,493
sonic hedgehog group medulloblastoma 1,482 | 1,482
colon cancer 1,475 | 1,475
adrenocortical carcinoma 1,427 | 1,427
Multiple myeloma 1,327 | 1,327
primary pancreatic ductal adenocarcinoma 1,271 | 1,271
juvenile dermatomyositis 1,189 | 1,189
Rheumatoid Arthritis 1,170 | 1,170
acute quadriplegic myopathy 1,157 | 1,157
atypical teratoid/rhabdoid tumor 1,095 | 1,095
spina bifida 1,064 | 1,064
cutaneous lupus erythematosus 1,056 | 1,056
nasopharyngeal carcinoma 1,056 | 1,056
dermatomyositis 966 | 966
Atopic dermatitis 944 | 944
active Crohn's disease 918 | 918
non primary Sjogren syndrome sicca 840 | 840
gastric carcinoma 832 | 832
primary Sjogren syndrome 788 | 788
acute myeloid leukemia 785 | 785
Waldenstrons macroglobulinemia 764 | 764
esophageal adenocarcinoma 737 | 737
tuberculosis and treatment for 6 months 686 | 686
progressive supranuclear palsy 674 | 674
aldosterone-producing adenoma 664 | 664
Alzheimer's disease 644 | 644
Obesity 616 | 616
Duchenne muscular dystrophy 602 | 602
Intellectual disability 573 | 573
pancreatic carcinoma 567 | 567
fibroadenoma 557 | 557
hepatocellular carcinoma 550 | 550
Down syndrome 548 | 548
Endometriosis 535 | 535
chronic rhinosinusitis 512 | 512
Schizophrenia 503 | 503
autosomal dominant Emery-Dreifuss muscular dystrophy 499 | 499
Multiple Sclerosis 498 | 498
mucosa-associated lymphoid tissue lymphoma 480 | 480
active ulcerative colitis 477 | 477
Prostatic Neoplasms 471 | 471
IGA Glomerulonephritis 454 | 454
gastric cancer 436 | 436
Amyotrophic Lateral Sclerosis 432 | 432
non-small cell lung carcinoma 413 | 413
Mammary Neoplasms 410 | 410
inflammatory breast cancer 404 | 404
Kidney disease 397 | 397
Neurodegenerative disease 383 | 383
sarcoidosis 368 | 368
Parkinson's disease 364 | 364
Asthma 349 | 349
glioblastoma multiforme 347 | 347
Epilepsy 346 | 346
Polycystic Ovary Syndrome 334 | 334
nephrosclerosis 329 | 329
tuberculosis and treatment for 3 months 327 | 327
Autistic Disorder 320 | 320

Tissue

Cardiovascular System 189 | 17,957
Liver and Pancreas 189 | 18,135
Digestive Tract 188 | 18,472
Female tissues 188 | 18,646
Male tissues 188 | 17,968
Nervous System 188 | 18,560
Endocrine System 187 | 18,511
Urinary Tract 187 | 18,443
Skin and soft tissues 186 | 18,114
Blood and immune system 184 | 17,994
Respiratory system 180 | 17,483

Target Family

Non-IDG 96 | 11,969
Enzyme 43 | 4,146
Transcription Factor 18 | 1,400
Ion Channel 9 | 341
Transporter 8 | 473
GPCR 7 | 408
Kinase 6 | 634
Nuclear Receptor 3 | 48
Epigenetic 2 | 242

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Thyroid adenoma-associated protein THADA Tbio Non-IDG -1.50722 29.2 46
Small G protein signaling modulator 2 SGSM2 Tbio Non-IDG -0.28255 1.93 58
VPS10 domain-containing receptor SorCS2 SORCS2 Tdark Non-IDG -0.69167 4.99 39
Potassium channel subfamily K member 16 KCNK16 Tdark Ion Channel -0.80937 5.88 10
Calmodulin-binding transcription activator 1 CAMTA1 Tbio Transcription Factor -1.44456 29.7 14
Protein tyrosine phosphatase domain-containing protein 1 PTPDC1 Tdark Enzyme 0.63 0.20 12
Voltage-dependent L-type calcium channel subunit alpha-1C CACNA1C Tclin Ion Channel -2.72211 489.2 316
Kinesin-like protein KIF11 KIF11 Tchem Non-IDG -2.57588 377.6 296
Protein sprouty homolog 2 SPRY2 Tbio Non-IDG -1.86730 81.5 178
Protein regulator of cytokinesis 1 PRC1 Tbio Non-IDG -0.85707 4.86 161