Development Level

Tbio 145 | 11,445
Tchem 23 | 1,598
Tclin 14 | 613
Tdark 12 | 6,588

Collection

Kinase: IDG Consortium (Target... 2 | 125
GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

abnormal bone structure 5 | 187
decreased lymphocyte cell numb... 5 | 83
increased lean body mass 5 | 172
preweaning lethality, incomple... 5 | 499
abnormal seminal vesicle morph... 4 | 114
decreased lean body mass 4 | 135
preweaning lethality, complete... 4 | 979
decreased grip strength 3 | 116
decreased total body fat amoun... 3 | 207
enlarged heart 3 | 210
impaired glucose tolerance 3 | 75
increased circulating chloride... 3 | 41
increased monocyte cell number 3 | 63
increased total body fat amoun... 3 | 134
abnormal behavior 2 | 298
abnormal eye morphology 2 | 68
abnormal heart morphology 2 | 162
abnormal locomotor behavior 2 | 24
decreased circulating HDL chol... 2 | 68
decreased circulating alkaline... 2 | 46
decreased circulating choleste... 2 | 93
decreased fasted circulating g... 2 | 65
decreased mean corpuscular vol... 2 | 79
decreased prepulse inhibition 2 | 82
decreased pulmonary respirator... 2 | 5
decreased vertical activity 2 | 208
enlarged lymph nodes 2 | 37
enlarged stomach 2 | 2
increased circulating HDL chol... 2 | 80
increased circulating alkaline... 2 | 122
increased circulating amylase ... 2 | 25
increased circulating sodium l... 2 | 71
increased lymphocyte cell numb... 2 | 32
increased red blood cell distr... 2 | 34
short tibia 2 | 97
small spleen 2 | 19
small testis 2 | 58
small thymus 2 | 16
tremors 2 | 39
abnormal cecum morphology 1 | 7
abnormal coat-hair pigmentatio... 1 | 64
abnormal gait 1 | 69
abnormal iris morphology 1 | 13
abnormal kidney morphology 1 | 65
abnormal optic disc morphology 1 | 10
abnormal retina morphology 1 | 71
abnormal sleep behavior 1 | 70
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
abnormal vibrissa morphology 1 | 25
abnormal vitreous body morphol... 1 | 10
cataract 1 | 92
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating creatini... 1 | 39
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased erythrocyte cell num... 1 | 62
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased mature B cell number 1 | 7
enlarged cecum 1 | 5
enlarged kidney 1 | 14
enlarged spleen 1 | 41
hydrometra 1 | 53
hypoactivity 1 | 132
impaired righting response 1 | 26
increased body length 1 | 32
increased circulating choleste... 1 | 66
increased circulating glucose ... 1 | 24
increased erythrocyte cell num... 1 | 39
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 96
increased mean corpuscular hem... 1 | 36
increased mean corpuscular vol... 1 | 92
increased neutrophil cell numb... 1 | 46
increased or absent threshold ... 1 | 101
increased prepulse inhibition 1 | 32
persistence of hyaloid vascula... 1 | 33
prolonged ST segment 1 | 36
small kidney 1 | 16
small superior vagus ganglion 1 | 74
thrombocytopenia 1 | 56

Disease

Systemic lupus erythematosus 194 | 194
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Endocrine System 177 | 18,159
Female tissues 176 | 17,400
Digestive Tract 175 | 17,369
Skin and soft tissues 175 | 17,230
Blood and immune system 174 | 16,909
Liver and Pancreas 174 | 16,750
Urinary Tract 173 | 16,678
Male tissues 172 | 17,142
Respiratory system 172 | 16,393
Nervous System 169 | 16,725
Cardiovascular System 164 | 15,192

Target Family

Non-IDG 124 | 12,091
Enzyme 34 | 4,145
Transcription Factor 16 | 1,400
Kinase 8 | 634
Transporter 4 | 473
Ion Channel 2 | 344
TF/Epigenetic 2 | 38
Epigenetic 1 | 242
GPCR 1 | 408
Nuclear Receptor 1 | 48
oGPCR 1 | 421

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
DNA topoisomerase 3-beta-1 TOP3B Tbio Enzyme -1.06981 9.54 153
Tumor necrosis factor receptor superfamily member 13C TNFRSF13C Tbio Non-IDG -2.48953 288.2 437
2'-5'-oligoadenylate synthase 3 OAS3 Tbio Enzyme -1.30083 17.8 141
Neurexin-1 NRXN1 Tbio Non-IDG -1.88807 125.1 174
Sodium channel protein type 10 subunit alpha SCN10A Tclin Ion Channel -3.17690 1469.3 126
Exosome component 10 EXOSC10 Tbio Non-IDG -2.45249 279.1 123
Interferon alpha-inducible protein 27, mitochondrial IFI27 Tbio Non-IDG -1.51419 33.3 0
Methylcytosine dioxygenase TET3 TET3 Tbio Enzyme -1.96016 82.2 167
Transportin-3 TNPO3 Tbio Non-IDG -1.74707 55.2 105
Low affinity immunoglobulin gamma Fc region receptor II-c FCGR2C Tbio Non-IDG -2.61667 619.4 0