Development Level

Tbio 63 | 11,445
Tchem 9 | 1,598
Tclin 8 | 613
Tdark 8 | 6,588

Collection

Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 8 | 979
decreased body weight 4 | 161
preweaning lethality, incomple... 4 | 499
abnormal behavior 2 | 298
abnormal embryo development 2 | 7
abnormal retina morphology 2 | 71
absent startle reflex 2 | 24
decreased prepulse inhibition 2 | 82
decreased startle reflex 2 | 75
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
increased or absent threshold ... 2 | 101
mammalian phenotype 2 | 17
syndactyly 2 | 23
abnormal behavioral response t... 1 | 66
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal brain morphology 1 | 13
abnormal coat-hair pigmentatio... 1 | 64
abnormal cranium morphology 1 | 36
abnormal digit morphology 1 | 10
abnormal embryo size 1 | 220
abnormal embryo turning 1 | 31
abnormal eye morphology 1 | 68
abnormal eye size 1 | 7
abnormal gait 1 | 69
abnormal head size 1 | 6
abnormal joint morphology 1 | 23
abnormal lens morphology 1 | 81
abnormal maxilla morphology 1 | 17
abnormal nail morphology 1 | 8
abnormal pelvic girdle bone mo... 1 | 12
abnormal pericardium morpholog... 1 | 26
abnormal placement of pupils 1 | 6
abnormal response to new envir... 1 | 10
abnormal snout morphology 1 | 23
abnormal vertebrae morphology 1 | 18
abnormal vitreous body morphol... 1 | 10
brachydactyly 1 | 19
cataract 1 | 92
decreased body length 1 | 101
decreased bone mineral density 1 | 126
decreased circulating amylase ... 1 | 28
decreased circulating creatini... 1 | 39
decreased erythrocyte cell num... 1 | 62
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
hydroencephaly 1 | 14
hydrops fetalis 1 | 1
hypoactivity 1 | 132
impaired pupillary reflex 1 | 26
increased circulating HDL chol... 1 | 80
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating free fat... 1 | 20
increased heart rate variabili... 1 | 7
increased large unstained cell... 1 | 5
increased lean body mass 1 | 172
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
increased prepulse inhibition 1 | 32
increased total body fat amoun... 1 | 134
microphthalmia 1 | 26
mydriasis 1 | 6
narrow eye opening 1 | 12
prenatal lethality prior to he... 1 | 87

Disease

Syndactyly 88 | 88
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Female tissues 85 | 17,400
Endocrine System 84 | 18,159
Digestive Tract 83 | 17,369
Male tissues 83 | 17,142
Skin and soft tissues 82 | 17,230
Urinary Tract 81 | 16,678
Nervous System 78 | 16,725
Blood and immune system 75 | 16,909
Liver and Pancreas 75 | 16,750
Respiratory system 74 | 16,393
Cardiovascular System 65 | 15,192

Target Family

Non-IDG 46 | 12,091
Transcription Factor 17 | 1,400
Enzyme 12 | 4,145
Kinase 7 | 634
Epigenetic 2 | 242
GPCR 2 | 408
Ion Channel 2 | 344

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Bardet-Biedl syndrome 4 protein BBS4 Tbio Non-IDG -1.53435 31.5 200
Extracellular matrix protein FRAS1 FRAS1 Tbio Non-IDG -1.51346 36.5 22
Chondroitin sulfate synthase 1 CHSY1 Tbio Enzyme -1.69082 48.5 101
Smoothened homolog SMO Tclin GPCR -1.17466 14.5 415
Limb region 1 protein homolog LMBR1 Tbio Non-IDG -2.39449 251.0 126
Homeobox protein Hox-D9 HOXD9 Tbio Transcription Factor -1.52954 36.2 137
WD repeat-containing protein 60 WDR60 Tbio Non-IDG -0.64761 3.98 23
Cytosolic Fe-S cluster assembly factor NUBP1 NUBP1 Tbio Non-IDG -1.31867 20.0 105
Ankyrin repeat and fibronectin type-III domain-containing protein 1 ANKFN1 Tdark Non-IDG 0.06 0.71 13
Meckel syndrome type 1 protein MKS1 Tbio Non-IDG -1.31837 20.5 59