Development Level

Tbio 76 | 11,651
Tclin 15 | 612
Tdark 15 | 6,593
Tchem 9 | 1,388

Collection

Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

abnormal behavior 3 | 298
preweaning lethality, incomple... 3 | 499
decreased caudal vertebrae num... 2 | 53
hyperactivity 2 | 148
increased fasted circulating g... 2 | 76
increased mean platelet volume 2 | 45
increased vertical activity 2 | 24
abnormal behavioral response t... 1 | 66
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal craniofacial morpholo... 1 | 33
abnormal cranium morphology 1 | 36
abnormal ear morphology 1 | 9
abnormal embryo size 1 | 220
abnormal embryonic autopod pla... 1 | 2
abnormal epididymis morphology 1 | 42
abnormal facial morphology 1 | 17
abnormal incisor morphology 1 | 4
abnormal placenta morphology 1 | 5
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal sleep behavior 1 | 70
abnormal spleen morphology 1 | 55
abnormal vertebral arch morpho... 1 | 9
abnormal whole-body plethysmog... 1 | 4
convulsive seizures 1 | 13
decreased KLRG1+ CD8 alpha bet... 1 | 2
decreased body length 1 | 101
decreased body weight 1 | 161
decreased circulating alanine ... 1 | 47
decreased circulating amylase ... 1 | 28
decreased circulating fructosa... 1 | 30
decreased circulating insulin ... 1 | 76
decreased circulating potassiu... 1 | 20
decreased circulating serum al... 1 | 82
decreased circulating triglyce... 1 | 79
decreased grip strength 1 | 116
decreased thermal nociceptive ... 1 | 2
decreased threshold for audito... 1 | 26
decreased vertical activity 1 | 208
edema 1 | 59
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged epididymis 1 | 31
eye hemorrhage 1 | 1
fusion of vertebral arches 1 | 7
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased body weight 1 | 25
increased bone mineral density 1 | 72
increased grip strength 1 | 41
increased lean body mass 1 | 172
increased monocyte cell number 1 | 63
increased or absent threshold ... 1 | 101
limb grasping 1 | 41
prenatal lethality 1 | 28
preweaning lethality, complete... 1 | 979
small kidney 1 | 16
small testis 1 | 58
tremors 1 | 39
unresponsive to tactile stimul... 1 | 8
vertebral transformation 1 | 12

Disease

Substance-Related Disorders 115 | 115
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Endocrine System 111 | 18,159
Female tissues 111 | 17,400
Male tissues 110 | 17,142
Digestive Tract 109 | 17,369
Skin and soft tissues 109 | 17,230
Blood and immune system 107 | 16,909
Liver and Pancreas 107 | 16,750
Nervous System 104 | 16,725
Respiratory system 104 | 16,393
Urinary Tract 104 | 16,678
Cardiovascular System 95 | 15,192

Target Family

Non-IDG 66 | 12,091
Enzyme 18 | 4,145
GPCR 7 | 408
Transcription Factor 7 | 1,400
Transporter 7 | 473
Kinase 5 | 634
Ion Channel 4 | 344
oGPCR 1 | 421

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
MAP kinase-interacting serine/threonine-protein kinase 1 MKNK1 Tchem Kinase -1.71576 46.7 408
Sodium-dependent serotonin transporter SLC6A4 Tclin Transporter -3.63283 4453.8 245
Mitochondrial pyruvate carrier 1 MPC1 Tbio Non-IDG -1.77095 56.4 96
Chromodomain-helicase-DNA-binding protein 1-like CHD1L Tbio Enzyme -2.22453 176.8 129
Proton myo-inositol cotransporter SLC2A13 Tbio Transporter -1.10021 10.8 71
Uncharacterized protein C10orf82 C10orf82 Tdark Non-IDG 0.00000 20
Programmed cell death 1 ligand 1 CD274 Tclin Non-IDG -3.53386 3285.3 993
D(2) dopamine receptor DRD2 Tclin GPCR -3.28700 1882.2 264
Pre-B-cell leukemia transcription factor 1 PBX1 Tbio Transcription Factor -2.30640 200.0 232
Membrane-associated transporter protein SLC45A2 Tbio Transporter -2.45584 276.5 83