Development Level

Tbio 88 | 11,651
Tchem 13 | 1,388
Tclin 10 | 612
Tdark 1 | 6,593

Collection

Kinase: IDG Consortium (Target... 1 | 125
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 13 | 979
abnormal behavior 4 | 298
decreased grip strength 4 | 116
embryonic lethality prior to o... 4 | 239
embryonic lethality prior to t... 4 | 278
preweaning lethality, incomple... 4 | 499
abnormal embryo size 3 | 220
decreased total body fat amoun... 3 | 207
hypoactivity 3 | 132
abnormal coat-hair pigmentatio... 2 | 64
abnormal retinal vasculature m... 2 | 27
abnormal snout morphology 2 | 23
abnormal tooth morphology 2 | 24
decreased body weight 2 | 161
decreased bone mineral density 2 | 126
decreased circulating amylase ... 2 | 28
decreased circulating aspartat... 2 | 34
decreased hemoglobin content 2 | 68
decreased leukocyte cell numbe... 2 | 73
decreased lymphocyte cell numb... 2 | 83
decreased mean corpuscular hem... 2 | 31
decreased mean corpuscular vol... 2 | 79
decreased prepulse inhibition 2 | 82
decreased respiratory quotient 2 | 16
decreased startle reflex 2 | 75
embryonic growth retardation 2 | 106
hyperactivity 2 | 148
impaired glucose tolerance 2 | 75
increased mean corpuscular hem... 2 | 96
male infertility 2 | 123
small superior vagus ganglion 2 | 74
abnormal behavioral response t... 1 | 66
abnormal cornea morphology 1 | 31
abnormal craniofacial morpholo... 1 | 33
abnormal cranium morphology 1 | 36
abnormal epididymis morphology 1 | 42
abnormal eye morphology 1 | 68
abnormal gait 1 | 69
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal neural tube closure 1 | 46
abnormal retinal inner nuclear... 1 | 8
abnormal seminal vesicle morph... 1 | 114
abnormal sleep behavior 1 | 70
abnormal tibia morphology 1 | 14
absent pinna reflex 1 | 23
cataract 1 | 92
corneal opacity 1 | 32
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased circulating alkaline... 1 | 46
decreased circulating bilirubi... 1 | 19
decreased circulating glucose ... 1 | 126
decreased circulating glycerol... 1 | 16
decreased circulating iron lev... 1 | 32
decreased circulating phosphat... 1 | 27
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased food intake 1 | 13
decreased heart left ventricle... 1 | 28
decreased heart weight 1 | 27
decreased hematocrit 1 | 46
decreased lactate dehydrogenas... 1 | 16
decreased lean body mass 1 | 135
decreased mean platelet volume 1 | 25
decreased neutrophil cell numb... 1 | 42
decreased red blood cell distr... 1 | 41
decreased total retina thickne... 1 | 17
decreased vertical activity 1 | 208
enlarged heart 1 | 210
enlarged lymph nodes 1 | 37
hydrometra 1 | 53
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating phosphat... 1 | 26
increased circulating potassiu... 1 | 29
increased circulating serum al... 1 | 22
increased circulating total pr... 1 | 28
increased circulating triglyce... 1 | 42
increased fasted circulating g... 1 | 76
increased fluid intake 1 | 1
increased heart weight 1 | 62
increased lean body mass 1 | 172
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
increased vertical activity 1 | 24
limb grasping 1 | 41
long tibia 1 | 25
microphthalmia 1 | 26
pale yolk sac 1 | 25
short tibia 1 | 97
shortened QT interval 1 | 4
thin ventricular wall 1 | 24
thrombocytosis 1 | 27
tremors 1 | 39
vertebral fusion 1 | 23

Disease

Speech Delay 112 | 112
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Endocrine System 112 | 18,159
Female tissues 112 | 17,400
Male tissues 112 | 17,142
Skin and soft tissues 112 | 17,230
Blood and immune system 111 | 16,909
Digestive Tract 111 | 17,369
Liver and Pancreas 111 | 16,750
Urinary Tract 111 | 16,678
Nervous System 110 | 16,725
Respiratory system 108 | 16,393
Cardiovascular System 103 | 15,192

Target Family

Non-IDG 37 | 12,091
Enzyme 36 | 4,145
Transcription Factor 14 | 1,400
Kinase 10 | 634
Epigenetic 8 | 242
Ion Channel 2 | 344
Transporter 2 | 473
GPCR 1 | 408
Nuclear Receptor 1 | 48
TF/Epigenetic 1 | 38

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase FTSJ1 Tbio Enzyme -1.64419 45.9 108
SET domain-containing protein 5 SETD5 Tbio Epigenetic -0.91515 9.39 43
Sialin SLC17A5 Tbio Transporter -2.93541 845.6 63
AP-4 complex subunit beta-1 AP4B1 Tbio Non-IDG -0.79214 6.23 124
V-type proton ATPase 116 kDa subunit a isoform 2 ATP6V0A2 Tbio Enzyme -2.46402 298.9 76
TERF1-interacting nuclear factor 2 TINF2 Tbio Non-IDG -2.03707 99.1 138
Paired amphipathic helix protein Sin3a SIN3A Tbio Non-IDG -1.93639 70.1 171
Histone acetyltransferase KAT6B KAT6B Tbio Epigenetic -2.30232 201.0 58
Nipped-B-like protein NIPBL Tbio Non-IDG -2.25874 186.3 134
ATP-sensitive inward rectifier potassium channel 10 KCNJ10 Tbio Ion Channel -2.43730 273.3 158