Development Level

Tbio 709 | 11,445
Tchem 222 | 1,598
Tclin 166 | 613
Tdark 63 | 6,588

Collection

Ion Channel: IDG Consortium (T... 14 | 99
GPCR: IDG Consortium (Targets) 11 | 126
Kinase: IDG Consortium (Target... 6 | 125
Kinase: IDG Consortium (Comple... 3 | 37
GPCR: IDG Consortium (Complete... 2 | 25

IMPC Phenotype

preweaning lethality, complete... 72 | 979
preweaning lethality, incomple... 44 | 499
abnormal behavior 29 | 298
decreased total body fat amoun... 27 | 207
embryonic lethality prior to t... 24 | 278
abnormal embryo size 19 | 220
abnormal heart morphology 18 | 162
embryonic lethality prior to o... 18 | 239
enlarged heart 18 | 210
abnormal bone structure 17 | 187
increased bone mineral content 17 | 108
increased lean body mass 17 | 172
decreased vertical activity 16 | 208
hyperactivity 16 | 148
decreased body weight 14 | 161
increased startle reflex 14 | 112
short tibia 14 | 97
decreased bone mineral content 13 | 151
decreased grip strength 13 | 116
hypoactivity 13 | 132
increased circulating alkaline... 13 | 122
increased total body fat amoun... 13 | 134
abnormal seminal vesicle morph... 12 | 114
decreased circulating choleste... 12 | 93
decreased lean body mass 12 | 135
decreased prepulse inhibition 12 | 82
decreased startle reflex 11 | 75
increased circulating triglyce... 11 | 42
abnormal retina morphology 10 | 71
decreased circulating alkaline... 10 | 46
decreased circulating glucose ... 10 | 126
decreased lymphocyte cell numb... 10 | 83
embryonic growth retardation 10 | 106
increased circulating sodium l... 10 | 71
increased mean corpuscular vol... 10 | 92
decreased circulating HDL chol... 9 | 68
decreased circulating insulin ... 9 | 76
impaired glucose tolerance 9 | 75
increased heart weight 9 | 62
small superior vagus ganglion 9 | 74
abnormal sleep behavior 8 | 70
decreased circulating serum al... 8 | 82
decreased circulating triglyce... 8 | 79
decreased heart left ventricle... 8 | 28
decreased mean corpuscular vol... 8 | 79
improved glucose tolerance 8 | 79
increased circulating chloride... 8 | 41
increased circulating choleste... 8 | 66
increased mean corpuscular hem... 8 | 96
increased monocyte cell number 8 | 63
increased or absent threshold ... 8 | 101
limb grasping 8 | 41
abnormal epididymis morphology 7 | 42
abnormal gait 7 | 69
cataract 7 | 92
decreased body length 7 | 101
decreased erythrocyte cell num... 7 | 62
decreased fasted circulating g... 7 | 65
decreased neutrophil cell numb... 7 | 42
increased bone mineral density 7 | 72
male infertility 7 | 123
prolonged ST segment 7 | 36
tremors 7 | 39
abnormal lens morphology 6 | 81
decreased circulating amylase ... 6 | 28
decreased hemoglobin content 6 | 68
hydrometra 6 | 53
increased fasted circulating g... 6 | 76
increased hemoglobin content 6 | 45
increased neutrophil cell numb... 6 | 46
prenatal lethality prior to he... 6 | 87
prolonged QT interval 6 | 38
thin ventricular wall 6 | 24
abnormal bone mineralization 5 | 38
abnormal testis morphology 5 | 43
decreased blood urea nitrogen ... 5 | 51
decreased caudal vertebrae num... 5 | 53
decreased circulating LDL chol... 5 | 38
decreased circulating aspartat... 5 | 34
decreased circulating creatini... 5 | 39
decreased heart weight 5 | 27
decreased mean corpuscular hem... 5 | 31
decreased mean platelet volume 5 | 25
decreased red blood cell distr... 5 | 41
impaired righting response 5 | 26
increased circulating HDL chol... 5 | 80
increased circulating alanine ... 5 | 13
increased circulating creatini... 5 | 38
increased circulating iron lev... 5 | 30
small testis 5 | 58
abnormal cornea morphology 4 | 31
abnormal cranium morphology 4 | 36
abnormal locomotor behavior 4 | 24
abnormal lung morphology 4 | 26
abnormal spleen morphology 4 | 55
cardiovascular system phenotyp... 4 | 36
decreased bone mineral density 4 | 126
decreased circulating total pr... 4 | 49
increased body length 4 | 32
persistence of hyaloid vascula... 4 | 33

Disease

Schizophrenia 1,160 | 1,160
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Endocrine System 1,119 | 18,159
Digestive Tract 1,087 | 17,369
Female tissues 1,084 | 17,400
Skin and soft tissues 1,084 | 17,230
Nervous System 1,076 | 16,725
Male tissues 1,062 | 17,142
Urinary Tract 1,060 | 16,678
Blood and immune system 1,057 | 16,909
Liver and Pancreas 1,050 | 16,750
Respiratory system 1,019 | 16,393
Cardiovascular System 940 | 15,192

Target Family

Non-IDG 559 | 12,091
Enzyme 251 | 4,145
GPCR 76 | 408
Transcription Factor 69 | 1,400
Kinase 67 | 634
Ion Channel 62 | 344
Transporter 40 | 473
Epigenetic 20 | 242
Nuclear Receptor 11 | 48
TF/Epigenetic 4 | 38
oGPCR 1 | 421

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Tyrosine-protein phosphatase non-receptor type 5 PTPN5 Tchem Enzyme -1.85420 70.8 225
Neuroplastin NPTN Tbio Non-IDG -2.31075 211.6 201
X-box-binding protein 1 XBP1 Tchem Transcription Factor -2.90444 780.2 514
F-box only protein 11 FBXO11 Tbio Non-IDG -1.53905 34.1 258
DNA topoisomerase 3-beta-1 TOP3B Tbio Enzyme -1.06981 9.54 153
Trace amine-associated receptor 6 TAAR6 Tbio GPCR -2.06244 115.1 64
Numb-like protein NUMBL Tbio Non-IDG -2.50313 317.9 171
Trace amine-associated receptor 1 TAAR1 Tclin GPCR -2.49444 308.8 117
Neurexin-1 NRXN1 Tbio Non-IDG -1.88807 125.1 174
Histone deacetylase 9 HDAC9 Tclin Epigenetic -2.27309 185.2 431