Development Level

Tbio 43 | 11,445
Tchem 8 | 1,598
Tclin 3 | 613

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 6 | 979
preweaning lethality, incomple... 3 | 499
abnormal spleen morphology 2 | 55
increased circulating triglyce... 2 | 42
abnormal esophagus morphology 1 | 5
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal pancreas morphology 1 | 13
abnormal retina morphology 1 | 71
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal skin coloration 1 | 25
abnormal snout morphology 1 | 23
abnormal testis morphology 1 | 43
abnormal thyroid gland morphol... 1 | 3
abnormal trachea morphology 1 | 3
abnormal urinary bladder morph... 1 | 11
absent adrenal gland 1 | 2
absent lymph nodes 1 | 3
anophthalmia 1 | 33
cystolithiasis 1 | 3
decreased blood urea nitrogen ... 1 | 51
decreased bone mineral density 1 | 126
decreased circulating glucose ... 1 | 126
decreased circulating triglyce... 1 | 79
decreased eosinophil cell numb... 1 | 24
decreased grip strength 1 | 116
decreased lymphocyte cell numb... 1 | 83
decreased neutrophil cell numb... 1 | 42
edema 1 | 59
embryonic lethality prior to o... 1 | 239
enlarged heart 1 | 210
enlarged kidney 1 | 14
enlarged lymph nodes 1 | 37
enlarged spleen 1 | 41
enlarged thymus 1 | 5
enlarged urinary bladder 1 | 8
hydrometra 1 | 53
impaired glucose tolerance 1 | 75
increased bone mineral content 1 | 108
increased circulating sodium l... 1 | 71
increased mean corpuscular hem... 1 | 96
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
polycystic kidney 1 | 15
small kidney 1 | 16
small superior vagus ganglion 1 | 74
urinary bladder obstruction 1 | 4

Disease

Retrognathia 54 | 54
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Endocrine System 54 | 18,159
Female tissues 54 | 17,400
Male tissues 54 | 17,142
Nervous System 54 | 16,725
Blood and immune system 53 | 16,909
Cardiovascular System 53 | 15,192
Digestive Tract 53 | 17,369
Liver and Pancreas 53 | 16,750
Skin and soft tissues 53 | 17,230
Urinary Tract 53 | 16,678
Respiratory system 52 | 16,393

Target Family

Non-IDG 27 | 12,091
Enzyme 10 | 4,145
Transcription Factor 8 | 1,400
Kinase 4 | 634
Epigenetic 3 | 242
Nuclear Receptor 1 | 48
Transporter 1 | 473

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Paired mesoderm homeobox protein 1 PRRX1 Tbio Transcription Factor -1.58479 38.8 304
40S ribosomal protein S19 RPS19 Tbio Non-IDG -3.14746 1380.8 267
DNA endonuclease RBBP8 RBBP8 Tbio Enzyme -2.17933 148.4 308
Treacle protein TCOF1 Tbio Non-IDG -3.44117 2743.5 131
ETS domain-containing transcription factor ERF ERF Tbio Transcription Factor -2.42588 268.8 257
Centrosomal protein of 152 kDa CEP152 Tbio Non-IDG -1.23896 18.1 117
T-box transcription factor TBX1 TBX1 Tbio Transcription Factor -1.99519 95.5 207
Nuclear factor 1 X-type NFIX Tbio Transcription Factor -1.70265 49.7 74
Paired box protein Pax-2 PAX2 Tbio Transcription Factor -2.68609 492.0 349
Peroxisomal multifunctional enzyme type 2 HSD17B4 Tbio Non-IDG -2.17283 152.2 275