Development Level

Tbio 183 | 11,445
Tclin 18 | 613
Tchem 17 | 1,598
Tdark 8 | 6,588

Collection

Ion Channel: IDG Consortium (T... 2 | 99
RFA-RM-18-021 2 | 328

IMPC Phenotype

preweaning lethality, complete... 19 | 979
decreased vertical activity 7 | 208
enlarged heart 7 | 210
embryonic lethality prior to o... 6 | 239
preweaning lethality, incomple... 6 | 499
embryonic lethality prior to t... 5 | 278
hypoactivity 5 | 132
increased lean body mass 5 | 172
abnormal behavior 4 | 298
abnormal heart morphology 4 | 162
enlarged lymph nodes 4 | 37
increased or absent threshold ... 4 | 101
increased total body fat amoun... 4 | 134
male infertility 4 | 123
abnormal bone structure 3 | 187
abnormal testis morphology 3 | 43
absent startle reflex 3 | 24
decreased body weight 3 | 161
decreased circulating choleste... 3 | 93
decreased total body fat amoun... 3 | 207
hyperactivity 3 | 148
impaired righting response 3 | 26
increased bone mineral density 3 | 72
increased circulating potassiu... 3 | 29
increased circulating sodium l... 3 | 71
increased mean corpuscular hem... 3 | 96
limb grasping 3 | 41
small testis 3 | 58
abnormal behavioral response t... 2 | 66
abnormal eye morphology 2 | 68
abnormal kidney morphology 2 | 65
abnormal lung morphology 2 | 26
abnormal retina morphology 2 | 71
abnormal vibrissa morphology 2 | 25
absent pinna reflex 2 | 23
decreased bone mineral content 2 | 151
decreased bone mineral density 2 | 126
decreased circulating amylase ... 2 | 28
decreased circulating glucose ... 2 | 126
decreased circulating serum al... 2 | 82
decreased circulating triglyce... 2 | 79
decreased fasted circulating g... 2 | 65
decreased lean body mass 2 | 135
decreased leukocyte cell numbe... 2 | 73
decreased lymphocyte cell numb... 2 | 83
decreased prepulse inhibition 2 | 82
decreased startle reflex 2 | 75
enlarged spleen 2 | 41
enlarged uterus 2 | 11
hydrometra 2 | 53
improved glucose tolerance 2 | 79
increased blood urea nitrogen ... 2 | 48
increased bone mineral content 2 | 108
increased circulating phosphat... 2 | 26
increased fasted circulating g... 2 | 76
increased heart rate 2 | 23
increased thermal nociceptive ... 2 | 9
prolonged PR interval 2 | 15
short tibia 2 | 97
shortened RR interval 2 | 17
small superior vagus ganglion 2 | 74
stereotypic behavior 2 | 3
trunk curl 2 | 16
abnormal coat-hair pigmentatio... 1 | 64
abnormal cornea morphology 1 | 31
abnormal craniofacial morpholo... 1 | 33
abnormal ear morphology 1 | 9
abnormal epididymis morphology 1 | 42
abnormal liver morphology 1 | 17
abnormal locomotor behavior 1 | 24
abnormal pancreas morphology 1 | 13
abnormal seminal vesicle morph... 1 | 114
abnormal whole-body plethysmog... 1 | 4
anophthalmia 1 | 33
cardiovascular system phenotyp... 1 | 36
convulsive seizures 1 | 13
decreased body length 1 | 101
decreased caudal vertebrae num... 1 | 53
decreased circulating calcium ... 1 | 36
decreased circulating creatini... 1 | 39
decreased circulating insulin ... 1 | 76
decreased circulating potassiu... 1 | 20
decreased neutrophil cell numb... 1 | 42
decreased red blood cell distr... 1 | 41
enlarged urinary bladder 1 | 8
impaired pupillary reflex 1 | 26
increased blood uric acid leve... 1 | 5
increased circulating alkaline... 1 | 122
increased circulating calcium ... 1 | 34
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased circulating fructosa... 1 | 13
increased heart weight 1 | 62
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased prepulse inhibition 1 | 32
increased startle reflex 1 | 112
thin ventricular wall 1 | 24
tremors 1 | 39
vertebral fusion 1 | 23

Disease

Retinitis Pigmentosa 226 | 226
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Endocrine System 222 | 18,159
Digestive Tract 218 | 17,369
Skin and soft tissues 216 | 17,230
Nervous System 214 | 16,725
Female tissues 213 | 17,400
Male tissues 211 | 17,142
Blood and immune system 210 | 16,909
Urinary Tract 208 | 16,678
Liver and Pancreas 206 | 16,750
Respiratory system 203 | 16,393
Cardiovascular System 183 | 15,192

Target Family

Non-IDG 114 | 12,091
Enzyme 71 | 4,145
Transcription Factor 10 | 1,400
GPCR 8 | 408
Ion Channel 8 | 344
Kinase 8 | 634
Transporter 5 | 473
Nuclear Receptor 1 | 48
oGPCR 1 | 421

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Peroxisome biogenesis factor 2 PEX2 Tbio Non-IDG -1.76849 57.3 170
Cytochrome c oxidase assembly protein COX15 homolog COX15 Tbio Enzyme -1.37513 23.0 104
Cytoglobin CYGB Tbio Non-IDG -3.10582 1269.7 202
Peroxisomal membrane protein PEX16 PEX16 Tbio Non-IDG -1.43594 27.8 78
Neural retina-specific leucine zipper protein NRL Tbio Transcription Factor -2.46080 279.4 74
Protocadherin-15 PCDH15 Tbio Non-IDG -1.83877 74.3 42
Harmonin USH1C Tbio Non-IDG -2.10689 124.7 188
Bardet-Biedl syndrome 4 protein BBS4 Tbio Non-IDG -1.53435 31.5 200
Electrogenic sodium bicarbonate cotransporter 1 SLC4A4 Tbio Transporter -2.63743 436.2 124
NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial NDUFS4 Tclin Enzyme -2.97252 871.7 197