Development Level

Tbio 89 | 11,651
Tchem 11 | 1,388
Tclin 4 | 612
Tdark 2 | 6,593

Collection

Kinase: IDG Consortium (Target... 1 | 125
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 6 | 979
abnormal retina morphology 4 | 71
preweaning lethality, incomple... 4 | 499
enlarged heart 3 | 210
hyperactivity 3 | 148
hypoactivity 3 | 132
abnormal behavior 2 | 298
decreased circulating calcium ... 2 | 36
decreased hemoglobin content 2 | 68
decreased mean corpuscular vol... 2 | 79
decreased vertical activity 2 | 208
embryonic lethality prior to t... 2 | 278
enlarged uterus 2 | 11
impaired pupillary reflex 2 | 26
increased mean corpuscular vol... 2 | 92
limb grasping 2 | 41
prolonged PR interval 2 | 15
abnormal behavioral response t... 1 | 66
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal embryo size 1 | 220
abnormal eye morphology 1 | 68
abnormal heart morphology 1 | 162
abnormal liver morphology 1 | 17
abnormal locomotor behavior 1 | 24
abnormal pelvic girdle bone mo... 1 | 12
abnormal pupil morphology 1 | 2
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
abnormal sleep behavior 1 | 70
abnormal testis morphology 1 | 43
abnormal whole-body plethysmog... 1 | 4
cataract 1 | 92
decreased body weight 1 | 161
decreased circulating amylase ... 1 | 28
decreased circulating free fat... 1 | 31
decreased circulating iron lev... 1 | 32
decreased circulating potassiu... 1 | 20
decreased circulating triglyce... 1 | 79
decreased hematocrit 1 | 46
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular hem... 1 | 31
decreased total body fat amoun... 1 | 207
embryonic growth retardation 1 | 106
enlarged spleen 1 | 41
hydrometra 1 | 53
increased blood uric acid leve... 1 | 5
increased body weight 1 | 25
increased cellular hemoglobin ... 1 | 1
increased circulating iron lev... 1 | 30
increased circulating potassiu... 1 | 29
increased circulating triglyce... 1 | 42
increased fasted circulating g... 1 | 76
increased heart weight 1 | 62
increased kidney weight 1 | 6
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 96
increased startle reflex 1 | 112
macrophthalmia 1 | 2
male infertility 1 | 123
mydriasis 1 | 6
premature death 1 | 5
small superior vagus ganglion 1 | 74
small testis 1 | 58

Disease

Retinal Degeneration 106 | 106
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Endocrine System 103 | 18,159
Digestive Tract 97 | 17,369
Skin and soft tissues 97 | 17,230
Blood and immune system 95 | 16,909
Nervous System 95 | 16,725
Female tissues 91 | 17,400
Male tissues 91 | 17,142
Liver and Pancreas 89 | 16,750
Urinary Tract 86 | 16,678
Respiratory system 85 | 16,393
Cardiovascular System 76 | 15,192

Target Family

Non-IDG 61 | 12,091
Enzyme 24 | 4,145
Transcription Factor 7 | 1,400
GPCR 4 | 408
Ion Channel 4 | 344
Kinase 4 | 634
Transporter 2 | 473

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein O-mannosyl-transferase 2 POMT2 Tbio Enzyme -1.48456 31.6 104
Ciliary neurotrophic factor CNTF Tbio Non-IDG -2.96004 1015.5 485
U4/U6 small nuclear ribonucleoprotein Prp4 PRPF4 Tchem Non-IDG -0.61497 4.52 86
Retinol dehydrogenase 12 RDH12 Tbio Enzyme -1.56819 38.9 67
3-hydroxyacyl-CoA dehydrogenase type-2 HSD17B10 Tbio Enzyme -2.13468 132.4 359
Melanopsin OPN4 Tbio GPCR -2.77246 589.6 65
Protein unc-119 homolog A UNC119 Tbio Non-IDG -2.04467 109.5 42
Protein O-mannosyl-transferase 1 POMT1 Tbio Enzyme -1.57372 38.3 123
Neural retina-specific leucine zipper protein NRL Tbio Transcription Factor -2.46080 279.4 74
Ceroid-lipofuscinosis neuronal protein 6 CLN6 Tbio Non-IDG -1.87357 0.00000 103