Development Level

Tbio 19 | 10,625
Tdark 6 | 7,003
Tchem 2 | 1,890
Tclin 1 | 602

IMPC Phenotype

abnormal behavior 3 | 226
decreased grip strength 3 | 123
abnormal tooth morphology 2 | 24
decreased body length 2 | 108
hypoactivity 2 | 89
preweaning lethality, complete... 2 | 633
short tibia 2 | 82
vertebral fusion 2 | 23
abnormal autopod morphology 1 | 1
abnormal bone structure 1 | 131
abnormal cranium morphology 1 | 32
abnormal digit morphology 1 | 13
abnormal embryo size 1 | 112
abnormal eye morphology 1 | 38
abnormal heart left ventricle ... 1 | 20
abnormal joint morphology 1 | 14
abnormal lens morphology 1 | 73
abnormal maxilla morphology 1 | 16
abnormal motor capabilities-co... 1 | 4
abnormal nail morphology 1 | 7
abnormal optic disc morphology 1 | 10
abnormal pericardium morpholog... 1 | 11
abnormal skin coloration 1 | 18
abnormal spine curvature 1 | 7
abnormal spleen morphology 1 | 36
abnormal stomach morphology 1 | 4
abnormal tail morphology 1 | 17
abnormal thoracic vertebrae mo... 1 | 16
abnormal tibia morphology 1 | 14
abnormal vocalization 1 | 21
absent teeth 1 | 4
aorta stenosis 1 | 1
brachydactyly 1 | 2
cataract 1 | 26
decreased CD5-positive gamma-d... 1 | 3
decreased alpha-beta T cell nu... 1 | 12
decreased body weight 1 | 174
decreased bone mineral content 1 | 157
decreased bone mineral density 1 | 126
decreased cardiac stroke volum... 1 | 3
decreased cervical vertebrae n... 1 | 12
decreased circulating calcium ... 1 | 33
decreased circulating insulin ... 1 | 75
decreased circulating magnesiu... 1 | 11
decreased heart weight 1 | 44
decreased kidney weight 1 | 7
decreased lean body mass 1 | 195
decreased mean corpuscular hem... 1 | 19
decreased mean corpuscular vol... 1 | 50
decreased rib number 1 | 59
decreased startle reflex 1 | 48
decreased total body fat amoun... 1 | 186
decreased vertical activity 1 | 22
edema 1 | 11
embryonic lethality prior to o... 1 | 148
embryonic lethality prior to t... 1 | 187
fusion of vertebral arches 1 | 7
hemorrhage 1 | 12
increased bone mineral content 1 | 92
increased circulating HDL chol... 1 | 63
increased circulating alkaline... 1 | 119
increased circulating aspartat... 1 | 17
increased circulating chloride... 1 | 43
increased circulating choleste... 1 | 53
increased circulating sodium l... 1 | 71
increased exploration in new e... 1 | 56
increased fasted circulating g... 1 | 68
increased gamma-delta T cell n... 1 | 16
increased hemoglobin content 1 | 45
increased lean body mass 1 | 107
increased mean corpuscular hem... 1 | 25
increased mean corpuscular vol... 1 | 91
increased or absent threshold ... 1 | 128
increased startle reflex 1 | 38
kinked tail 1 | 3
prenatal lethality 1 | 16
preweaning lethality, incomple... 1 | 260
short tail 1 | 4
shortened PQ interval 1 | 6
straub tail 1 | 26
thrombocytopenia 1 | 46
trunk curl 1 | 15

Disease

Restless legs syndrome 28 | 28
ovarian cancer 8,491 | 8,491
osteosarcoma 7,933 | 7,933
psoriasis 6,685 | 6,685
medulloblastoma, large-cell 6,234 | 6,234
glioblastoma 5,572 | 5,572
lung cancer 4,473 | 4,473
atypical teratoid / rhabdoid tumor 4,369 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 3,289 | 3,289
malignant mesothelioma 3,163 | 3,163
Breast cancer 3,098 | 3,098
pilocytic astrocytoma 3,086 | 3,086
primitive neuroectodermal tumor 3,031 | 3,031
intraductal papillary-mucinous carcinoma (IPMC) 2,988 | 2,988
intraductal papillary-mucinous adenoma (IPMA) 2,956 | 2,956
invasive ductal carcinoma 2,950 | 2,950
oligodendroglioma 2,849 | 2,849
lung carcinoma 2,844 | 2,844
non-small cell lung cancer 2,798 | 2,798
lung adenocarcinoma 2,714 | 2,714
pediatric high grade glioma 2,712 | 2,712
ependymoma 2,514 | 2,514
Cancer 2,346 | 2,346
pancreatic cancer 2,300 | 2,300
interstitial cystitis 2,299 | 2,299
subependymal giant cell astrocytoma 2,287 | 2,287
group 3 medulloblastoma 2,254 | 2,254
astrocytic glioma 2,241 | 2,241
adult high grade glioma 2,148 | 2,148
Carcinoma 2,147 | 2,147
ulcerative colitis 2,087 | 2,087
pituitary cancer 1,972 | 1,972
Pick disease 1,893 | 1,893
group 4 medulloblastoma 1,875 | 1,875
pancreatic ductal adenocarcinoma liver metastasis 1,795 | 1,795
ductal carcinoma in situ 1,745 | 1,745
cystic fibrosis 1,670 | 1,670
diabetes mellitus 1,663 | 1,663
breast carcinoma 1,614 | 1,614
tuberculosis 1,563 | 1,563
posterior fossa group B ependymoma 1,530 | 1,530
medulloblastoma 1,524 | 1,524
posterior fossa group A ependymoma 1,511 | 1,511
astrocytoma 1,493 | 1,493
sonic hedgehog group medulloblastoma 1,482 | 1,482
colon cancer 1,475 | 1,475
adrenocortical carcinoma 1,427 | 1,427
Multiple myeloma 1,327 | 1,327
primary pancreatic ductal adenocarcinoma 1,271 | 1,271
juvenile dermatomyositis 1,189 | 1,189
Rheumatoid Arthritis 1,170 | 1,170
acute quadriplegic myopathy 1,157 | 1,157
atypical teratoid/rhabdoid tumor 1,095 | 1,095
spina bifida 1,064 | 1,064
cutaneous lupus erythematosus 1,056 | 1,056
nasopharyngeal carcinoma 1,056 | 1,056
dermatomyositis 966 | 966
Atopic dermatitis 944 | 944
active Crohn's disease 918 | 918
non primary Sjogren syndrome sicca 840 | 840
gastric carcinoma 832 | 832
primary Sjogren syndrome 788 | 788
acute myeloid leukemia 785 | 785
Waldenstrons macroglobulinemia 764 | 764
esophageal adenocarcinoma 737 | 737
tuberculosis and treatment for 6 months 686 | 686
progressive supranuclear palsy 674 | 674
aldosterone-producing adenoma 664 | 664
Alzheimer's disease 644 | 644
Obesity 616 | 616
Duchenne muscular dystrophy 602 | 602
Intellectual disability 573 | 573
pancreatic carcinoma 567 | 567
fibroadenoma 557 | 557
hepatocellular carcinoma 550 | 550
Down syndrome 548 | 548
Endometriosis 535 | 535
chronic rhinosinusitis 512 | 512
Schizophrenia 503 | 503
autosomal dominant Emery-Dreifuss muscular dystrophy 499 | 499
Multiple Sclerosis 498 | 498
mucosa-associated lymphoid tissue lymphoma 480 | 480
active ulcerative colitis 477 | 477
Prostatic Neoplasms 471 | 471
IGA Glomerulonephritis 454 | 454
gastric cancer 436 | 436
Amyotrophic Lateral Sclerosis 432 | 432
non-small cell lung carcinoma 413 | 413
Mammary Neoplasms 410 | 410
inflammatory breast cancer 404 | 404
Kidney disease 397 | 397
Neurodegenerative disease 383 | 383
sarcoidosis 368 | 368
Parkinson's disease 364 | 364
Asthma 349 | 349
glioblastoma multiforme 347 | 347
Epilepsy 346 | 346
Polycystic Ovary Syndrome 334 | 334
nephrosclerosis 329 | 329
tuberculosis and treatment for 3 months 327 | 327
Autistic Disorder 320 | 320

Tissue

Blood and immune system 28 | 17,994
Cardiovascular System 28 | 17,957
Digestive Tract 28 | 18,472
Endocrine System 28 | 18,511
Female tissues 28 | 18,646
Liver and Pancreas 28 | 18,135
Male tissues 28 | 17,968
Nervous System 28 | 18,560
Skin and soft tissues 28 | 18,114
Urinary Tract 28 | 18,443
Respiratory system 26 | 17,483

Target Family

Non-IDG 16 | 11,969
Enzyme 6 | 4,146
Transcription Factor 3 | 1,400
Ion Channel 1 | 341
Kinase 1 | 634
Transporter 1 | 473

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
BTB/POZ domain-containing protein 9 BTBD9 Tbio Non-IDG -1.30579 21.1 87
Decaprenyl-diphosphate synthase subunit 2 PDSS2 Tbio Enzyme -1.68757 48.4 133
Sodium-dependent dopamine transporter SLC6A3 Tclin Transporter -3.57190 3495.1 271
Orexin HCRT Tbio Non-IDG -3.24848 2104.5 162
Ataxin-3 ATXN3 Tbio Non-IDG -2.85838 721.6 233
DET1 homolog DET1 Tdark Non-IDG -1.23109 17.3 16
Dual specificity mitogen-activated protein kinase kinase 5 MAP2K5 Tchem Kinase -1.86736 59.4 368
BTB/POZ domain-containing protein KCTD18 KCTD18 Tdark Non-IDG 0.15 0.67 49
Serine/threonine-protein phosphatase 4 catalytic subunit PPP4C Tbio Enzyme -2.37479 260.9 290
Flap endonuclease GEN homolog 1 GEN1 Tbio Enzyme -2.04306 106.0 63