Development Level

Tbio 35 | 11,445
Tchem 35 | 1,598
Tclin 16 | 613

IMPC Phenotype

abnormal heart morphology 3 | 162
abnormal testis morphology 3 | 43
decreased circulating insulin ... 3 | 76
enlarged heart 3 | 210
preweaning lethality, incomple... 3 | 499
short tibia 3 | 97
small testis 3 | 58
abnormal behavior 2 | 298
abnormal epididymis morphology 2 | 42
abnormal lung morphology 2 | 26
decreased vertical activity 2 | 208
embryonic lethality prior to t... 2 | 278
enlarged epididymis 2 | 31
enlarged uterus 2 | 11
increased bone mineral content 2 | 108
increased fasted circulating g... 2 | 76
preweaning lethality, complete... 2 | 979
abnormal bone structure 1 | 187
abnormal cecum morphology 1 | 7
abnormal embryo size 1 | 220
abnormal forebrain development 1 | 20
abnormal gait 1 | 69
abnormal hindbrain development 1 | 16
abnormal lens morphology 1 | 81
abnormal liver morphology 1 | 17
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal spleen morphology 1 | 55
abnormal vibrissa morphology 1 | 25
absent seminal vesicle 1 | 4
absent startle reflex 1 | 24
cataract 1 | 92
convulsive seizures 1 | 13
decreased body length 1 | 101
decreased circulating aspartat... 1 | 34
decreased circulating bilirubi... 1 | 19
decreased circulating glucose ... 1 | 126
decreased heart weight 1 | 27
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular vol... 1 | 79
decreased total body fat amoun... 1 | 207
embryonic growth retardation 1 | 106
enlarged adrenal glands 1 | 3
enlarged cecum 1 | 5
enlarged heart atrium 1 | 4
enlarged kidney 1 | 14
enlarged spleen 1 | 41
female infertility 1 | 60
hydrometra 1 | 53
hyperactivity 1 | 148
impaired pupillary reflex 1 | 26
impaired righting response 1 | 26
increased blood uric acid leve... 1 | 5
increased body length 1 | 32
increased bone mineral density 1 | 72
increased circulating chloride... 1 | 41
increased eosinophil cell numb... 1 | 11
increased granulocyte number 1 | 1
increased heart rate 1 | 23
increased mean corpuscular vol... 1 | 92
increased neutrophil cell numb... 1 | 46
increased spleen weight 1 | 10
irregularly shaped pupil 1 | 7
limb grasping 1 | 41
male infertility 1 | 123
polycystic kidney 1 | 15
shortened RR interval 1 | 17
small seminal vesicle 1 | 10
small superior vagus ganglion 1 | 74
small uterus 1 | 3
vertebral fusion 1 | 23

Disease

Reperfusion Injury 86 | 86
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Digestive Tract 86 | 17,369
Endocrine System 85 | 18,159
Female tissues 85 | 17,400
Male tissues 84 | 17,142
Respiratory system 84 | 16,393
Skin and soft tissues 84 | 17,230
Blood and immune system 83 | 16,909
Liver and Pancreas 83 | 16,750
Nervous System 82 | 16,725
Urinary Tract 82 | 16,678
Cardiovascular System 77 | 15,192

Target Family

Non-IDG 42 | 12,091
Enzyme 27 | 4,145
Transcription Factor 7 | 1,400
Kinase 4 | 634
GPCR 2 | 408
Nuclear Receptor 2 | 48
Ion Channel 1 | 344
Transporter 1 | 473

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cytochrome b-245 heavy chain CYBB Tchem Ion Channel -3.09698 1276.8 315
Heat shock protein beta-1 HSPB1 Tchem Non-IDG -2.97780 974.9 1992
Choline O-acetyltransferase CHAT Tchem Enzyme -3.40175 2597.2 436
C-C motif chemokine 2 CCL2 Tchem Non-IDG -3.84820 7088.3 1260
Alanine aminotransferase 1 GPT Tbio Enzyme -2.47451 285.2 217
Phospholipase A2, membrane associated PLA2G2A Tchem Enzyme -2.83666 743.3 137
Prostaglandin G/H synthase 1 PTGS1 Tclin Enzyme -3.23035 1641.3 479
Estrogen sulfotransferase SULT1E1 Tchem Enzyme -2.97379 932.9 156
Nitric oxide synthase, inducible NOS2 Tchem Enzyme -3.35134 2277.5 752
Prostaglandin G/H synthase 2 PTGS2 Tclin Enzyme -4.06834 12504.5 731