Development Level

Tbio 29 | 10,625
Tchem 8 | 1,890
Tdark 6 | 7,003
Tclin 2 | 602

IMPC Phenotype

increased grip strength 3 | 83
decreased CD4-positive, CD25-p... 2 | 24
decreased mature B cell number 2 | 25
decreased total body fat amoun... 2 | 186
increased lean body mass 2 | 107
preweaning lethality, complete... 2 | 633
abnormal behavior 1 | 226
absent startle reflex 1 | 15
decreased B cell number 1 | 30
decreased CD4-positive NK T ce... 1 | 4
decreased CD4-positive, alpha ... 1 | 19
decreased CD8-positive, alpha-... 1 | 26
decreased Ly6C low monocyte nu... 1 | 23
decreased Ly6C-positive immatu... 1 | 4
decreased Ly6C-positive mature... 1 | 4
decreased NK T cell number 1 | 28
decreased NK cell number 1 | 16
decreased T cell number 1 | 31
decreased alpha-beta T cell nu... 1 | 12
decreased body weight 1 | 174
decreased circulating free fat... 1 | 39
decreased circulating serum al... 1 | 79
decreased effector memory CD4-... 1 | 6
decreased effector memory CD8-... 1 | 24
decreased eosinophil cell numb... 1 | 41
decreased fasted circulating g... 1 | 49
decreased gamma-delta T cell n... 1 | 18
decreased grip strength 1 | 123
decreased large unstained cell... 1 | 3
decreased late germinal center... 1 | 2
decreased leukocyte cell numbe... 1 | 54
decreased lumbar vertebrae num... 1 | 62
decreased lymphocyte cell numb... 1 | 9
decreased mean corpuscular hem... 1 | 34
decreased memory-marker CD4-ne... 1 | 4
decreased memory-marker CD4-po... 1 | 4
decreased neutrophil cell numb... 1 | 37
hypoactivity 1 | 89
immune system phenotype 1 | 17
increased CD11b-high dendritic... 1 | 5
increased CD4-negative NK T ce... 1 | 4
increased CD4-positive, CD25-p... 1 | 18
increased body length 1 | 20
increased body weight 1 | 42
increased circulating HDL chol... 1 | 63
increased circulating alanine ... 1 | 11
increased circulating aspartat... 1 | 17
increased circulating bilirubi... 1 | 16
increased circulating choleste... 1 | 53
increased circulating triglyce... 1 | 24
increased early germinal cente... 1 | 2
increased effector memory CD4-... 1 | 15
increased effector memory CD8-... 1 | 14
increased exploration in new e... 1 | 56
increased granulocyte number 1 | 8
increased kidney weight 1 | 4
increased lactate dehydrogenas... 1 | 3
increased leukocyte cell numbe... 1 | 37
increased mean corpuscular hem... 1 | 93
increased monocyte cell number 1 | 27
increased neutrophil cell numb... 1 | 15
increased sacral vertebrae num... 1 | 62
preweaning lethality, incomple... 1 | 260
vertebral fusion 1 | 23

Disease

Primary biliary cirrhosis 45 | 45
ovarian cancer 8,491 | 8,491
osteosarcoma 7,933 | 7,933
psoriasis 6,685 | 6,685
medulloblastoma, large-cell 6,234 | 6,234
glioblastoma 5,572 | 5,572
lung cancer 4,473 | 4,473
atypical teratoid / rhabdoid tumor 4,369 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 3,289 | 3,289
malignant mesothelioma 3,163 | 3,163
Breast cancer 3,098 | 3,098
pilocytic astrocytoma 3,086 | 3,086
primitive neuroectodermal tumor 3,031 | 3,031
intraductal papillary-mucinous carcinoma (IPMC) 2,988 | 2,988
intraductal papillary-mucinous adenoma (IPMA) 2,956 | 2,956
invasive ductal carcinoma 2,950 | 2,950
oligodendroglioma 2,849 | 2,849
lung carcinoma 2,844 | 2,844
non-small cell lung cancer 2,798 | 2,798
lung adenocarcinoma 2,714 | 2,714
pediatric high grade glioma 2,712 | 2,712
ependymoma 2,514 | 2,514
Cancer 2,346 | 2,346
pancreatic cancer 2,300 | 2,300
interstitial cystitis 2,299 | 2,299
subependymal giant cell astrocytoma 2,287 | 2,287
group 3 medulloblastoma 2,254 | 2,254
astrocytic glioma 2,241 | 2,241
adult high grade glioma 2,148 | 2,148
Carcinoma 2,147 | 2,147
ulcerative colitis 2,087 | 2,087
pituitary cancer 1,972 | 1,972
Pick disease 1,893 | 1,893
group 4 medulloblastoma 1,875 | 1,875
pancreatic ductal adenocarcinoma liver metastasis 1,795 | 1,795
ductal carcinoma in situ 1,745 | 1,745
cystic fibrosis 1,670 | 1,670
diabetes mellitus 1,663 | 1,663
breast carcinoma 1,614 | 1,614
tuberculosis 1,563 | 1,563
posterior fossa group B ependymoma 1,530 | 1,530
medulloblastoma 1,524 | 1,524
posterior fossa group A ependymoma 1,511 | 1,511
astrocytoma 1,493 | 1,493
sonic hedgehog group medulloblastoma 1,482 | 1,482
colon cancer 1,475 | 1,475
adrenocortical carcinoma 1,427 | 1,427
Multiple myeloma 1,327 | 1,327
primary pancreatic ductal adenocarcinoma 1,271 | 1,271
juvenile dermatomyositis 1,189 | 1,189
Rheumatoid Arthritis 1,170 | 1,170
acute quadriplegic myopathy 1,157 | 1,157
atypical teratoid/rhabdoid tumor 1,095 | 1,095
spina bifida 1,064 | 1,064
cutaneous lupus erythematosus 1,056 | 1,056
nasopharyngeal carcinoma 1,056 | 1,056
dermatomyositis 966 | 966
Atopic dermatitis 944 | 944
active Crohn's disease 918 | 918
non primary Sjogren syndrome sicca 840 | 840
gastric carcinoma 832 | 832
primary Sjogren syndrome 788 | 788
acute myeloid leukemia 785 | 785
Waldenstrons macroglobulinemia 764 | 764
esophageal adenocarcinoma 737 | 737
tuberculosis and treatment for 6 months 686 | 686
progressive supranuclear palsy 674 | 674
aldosterone-producing adenoma 664 | 664
Alzheimer's disease 644 | 644
Obesity 616 | 616
Duchenne muscular dystrophy 602 | 602
Intellectual disability 573 | 573
pancreatic carcinoma 567 | 567
fibroadenoma 557 | 557
hepatocellular carcinoma 550 | 550
Down syndrome 548 | 548
Endometriosis 535 | 535
chronic rhinosinusitis 512 | 512
Schizophrenia 503 | 503
autosomal dominant Emery-Dreifuss muscular dystrophy 499 | 499
Multiple Sclerosis 498 | 498
mucosa-associated lymphoid tissue lymphoma 480 | 480
active ulcerative colitis 477 | 477
Prostatic Neoplasms 471 | 471
IGA Glomerulonephritis 454 | 454
gastric cancer 436 | 436
Amyotrophic Lateral Sclerosis 432 | 432
non-small cell lung carcinoma 413 | 413
Mammary Neoplasms 410 | 410
inflammatory breast cancer 404 | 404
Kidney disease 397 | 397
Neurodegenerative disease 383 | 383
sarcoidosis 368 | 368
Parkinson's disease 364 | 364
Asthma 349 | 349
glioblastoma multiforme 347 | 347
Epilepsy 346 | 346
Polycystic Ovary Syndrome 334 | 334
nephrosclerosis 329 | 329
tuberculosis and treatment for 3 months 327 | 327
Autistic Disorder 320 | 320

Tissue

Blood and immune system 45 | 17,994
Digestive Tract 45 | 18,472
Female tissues 45 | 18,646
Liver and Pancreas 45 | 18,135
Male tissues 45 | 17,968
Skin and soft tissues 45 | 18,114
Urinary Tract 45 | 18,443
Cardiovascular System 44 | 17,957
Endocrine System 44 | 18,511
Nervous System 44 | 18,560
Respiratory system 44 | 17,483

Target Family

Non-IDG 25 | 11,969
Enzyme 7 | 4,146
Transcription Factor 4 | 1,400
Transporter 3 | 473
TF/Epigenetic 2 | 38
Epigenetic 1 | 242
GPCR 1 | 408
Kinase 1 | 634
Nuclear Receptor 1 | 48

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Zinc finger protein Aiolos IKZF3 Tbio Transcription Factor -1.78743 55.0 277
Interleukin-7 receptor subunit alpha IL7R Tbio Non-IDG -2.76199 528.6 688
Transcription factor Spi-B SPIB Tbio Transcription Factor -1.78372 61.2 109
Complex I assembly factor TIMMDC1, mitochondrial TIMMDC1 Tdark Non-IDG -0.53832 3.93 9
Engulfment and cell motility protein 1 ELMO1 Tbio Non-IDG -1.59668 42.1 164
Exocyst complex component 3-like protein 4 EXOC3L4 Tdark Non-IDG 0.48 0.25 5
Ribosomal protein S6 kinase alpha-4 RPS6KA4 Tchem Kinase -1.06743 12.4 142
Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial DBT Tbio Enzyme -2.36450 229.7 95
DNA repair protein RAD51 homolog 2 RAD51B Tbio Non-IDG -1.91381 85.0 142
Protein CLEC16A CLEC16A Tbio Non-IDG -1.60632 38.5 124