Development Level

Tbio 81 | 11,178
Tchem 12 | 1,885
Tdark 12 | 6,569
Tclin 1 | 612

Collection

Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 16 | 979
decreased body weight 4 | 161
embryonic lethality prior to t... 4 | 278
preweaning lethality, incomple... 4 | 499
abnormal behavior 3 | 298
abnormal embryo size 3 | 220
increased circulating alkaline... 3 | 122
increased total body fat amoun... 3 | 134
abnormal craniofacial morpholo... 2 | 33
abnormal eye morphology 2 | 68
abnormal gait 2 | 69
abnormal neural tube closure 2 | 46
decreased circulating glucose ... 2 | 126
decreased grip strength 2 | 116
decreased lean body mass 2 | 135
decreased prepulse inhibition 2 | 82
decreased respiratory quotient 2 | 16
embryonic growth retardation 2 | 106
enlarged lymph nodes 2 | 37
hypoactivity 2 | 132
impaired glucose tolerance 2 | 75
increased body weight 2 | 25
increased fasted circulating g... 2 | 76
long tibia 2 | 25
male infertility 2 | 123
small superior vagus ganglion 2 | 74
abnormal QT variability 1 | 10
abnormal behavioral response t... 1 | 66
abnormal embryo turning 1 | 31
abnormal facial morphology 1 | 17
abnormal forebrain development 1 | 20
abnormal forebrain morphology 1 | 10
abnormal heart left ventricle ... 1 | 16
abnormal hindbrain development 1 | 16
abnormal hindbrain morphology 1 | 10
abnormal lens morphology 1 | 81
abnormal limb bud morphology 1 | 17
abnormal limb morphology 1 | 13
abnormal liver size 1 | 5
abnormal midbrain development 1 | 20
abnormal midbrain morphology 1 | 10
abnormal pelvic girdle bone mo... 1 | 12
abnormal placenta size 1 | 20
abnormal response to tactile s... 1 | 17
abnormal retina morphology 1 | 71
abnormal retinal blood vessel ... 1 | 26
abnormal retinal inner nuclear... 1 | 8
abnormal retinal vasculature m... 1 | 27
abnormal startle reflex 1 | 15
abnormal stomach morphology 1 | 10
abnormal testis morphology 1 | 43
anophthalmia 1 | 33
cataract 1 | 92
cleft palate 1 | 8
cyanosis 1 | 7
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased cardiac stroke volum... 1 | 6
decreased circulating alkaline... 1 | 46
decreased circulating aspartat... 1 | 34
decreased circulating bilirubi... 1 | 19
decreased circulating creatini... 1 | 39
decreased circulating free fat... 1 | 31
decreased heart rate variabili... 1 | 13
decreased heart weight 1 | 27
decreased spleen weight 1 | 10
decreased total body fat amoun... 1 | 207
edema 1 | 59
enlarged urinary bladder 1 | 8
enlarged uterus 1 | 11
hydrometra 1 | 53
hyperactivity 1 | 148
increased circulating alanine ... 1 | 13
increased circulating aspartat... 1 | 15
increased circulating glucose ... 1 | 24
increased circulating phosphat... 1 | 26
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 42
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased prepulse inhibition 1 | 32
increased startle reflex 1 | 112
limb grasping 1 | 41
microphthalmia 1 | 26
pale liver 1 | 6
pale yolk sac 1 | 25
pallor 1 | 34
persistence of hyaloid vascula... 1 | 33
polydactyly 1 | 7
prolonged PR interval 1 | 15
prolonged QRS complex duration 1 | 8
prolonged QT interval 1 | 38
short tibia 1 | 97
shortened QT interval 1 | 4
small testis 1 | 58

Disease

Polydactyly 106 | 106
Carcinoma 11,192 | 11,192
ovarian cancer 8,297 | 8,297
osteosarcoma 7,766 | 7,766
psoriasis 6,514 | 6,514
medulloblastoma, large-cell 6,086 | 6,086
glioblastoma 5,635 | 5,635
atypical teratoid / rhabdoid tumor 4,971 | 4,971
lung cancer 4,607 | 4,607
ependymoma 4,559 | 4,559
group 3 medulloblastoma 4,002 | 4,002
adult high grade glioma 3,701 | 3,701
Breast cancer 3,469 | 3,469
intraductal papillary-mucinous neoplasm (IPMN) 3,204 | 3,204
malignant mesothelioma 3,135 | 3,135
Astrocytoma, Pilocytic 3,006 | 3,006
primitive neuroectodermal tumor 2,957 | 2,957
intraductal papillary-mucinous carcinoma (IPMC) 2,902 | 2,902
intraductal papillary-mucinous adenoma (IPMA) 2,872 | 2,872
invasive ductal carcinoma 2,867 | 2,867
non-small cell lung cancer 2,799 | 2,799
oligodendroglioma 2,768 | 2,768
lung carcinoma 2,755 | 2,755
lung adenocarcinoma 2,627 | 2,627
Kidney cancer 2,548 | 2,548
astrocytic glioma 2,530 | 2,530
Cancer 2,388 | 2,388
pancreatic cancer 2,322 | 2,322
interstitial cystitis 2,237 | 2,237
subependymal giant cell astrocytoma 2,230 | 2,230
tuberculosis 1,963 | 1,963
pituitary cancer 1,915 | 1,915
pancreatic ductal adenocarcinoma liver metastasis 1,911 | 1,911
Pick disease 1,856 | 1,856
group 4 medulloblastoma 1,806 | 1,806
ulcerative colitis 1,765 | 1,765
ductal carcinoma in situ 1,686 | 1,686
diabetes mellitus 1,683 | 1,683
cystic fibrosis 1,629 | 1,629
breast carcinoma 1,589 | 1,589
colon cancer 1,428 | 1,428
Autosomal recessive predisposition 1,407 | 1,407
adrenocortical carcinoma 1,385 | 1,385
Multiple myeloma 1,296 | 1,296
Rheumatoid arthritis 1,156 | 1,156
juvenile dermatomyositis 1,147 | 1,147
Schizophrenia 1,136 | 1,136
acute quadriplegic myopathy 1,133 | 1,133
astrocytoma 1,113 | 1,113
primary pancreatic ductal adenocarcinoma 1,071 | 1,071
spina bifida 1,053 | 1,053
pediatric high grade glioma 1,035 | 1,035
nasopharyngeal carcinoma 1,024 | 1,024
cutaneous lupus erythematosus 1,016 | 1,016
Intellectual disability 998 | 998
dermatomyositis 941 | 941
Atopic dermatitis 915 | 915
active Crohn's disease 882 | 882
non primary Sjogren syndrome sicca 861 | 861
gastric carcinoma 781 | 781
Epilepsy 775 | 775
acute myeloid leukemia 760 | 760
Waldenstrons macroglobulinemia 742 | 742
active ulcerative colitis 736 | 736
Liver Cirrhosis, Experimental 733 | 733
primary Sjogren syndrome 710 | 710
medulloblastoma 702 | 702
esophageal adenocarcinoma 696 | 696
Melanoma 689 | 689
progressive supranuclear palsy 656 | 656
Obesity 655 | 655
Bipolar Disorder 646 | 646
aldosterone-producing adenoma 646 | 646
Alzheimer's disease 640 | 640
Dull intelligence 634 | 634
Low intelligence 634 | 634
Mental Retardation 634 | 634
Mental deficiency 634 | 634
Poor school performance 634 | 634
Cognitive delay 596 | 596
Global developmental delay 596 | 596
Mental and motor retardation 596 | 596
Liver cancer 589 | 589
Duchenne muscular dystrophy 587 | 587
Seizures 584 | 584
Muscle hypotonia 562 | 562
pancreatic carcinoma 555 | 555
fibroadenoma 538 | 538
hepatocellular carcinoma 536 | 536
Multiple Sclerosis 527 | 527
Endometriosis 521 | 521
Short stature 514 | 514
chronic rhinosinusitis 505 | 505
autosomal dominant Emery-Dreifuss muscular dystrophy 492 | 492
Down syndrome 480 | 480
mucosa-associated lymphoid tissue lymphoma 473 | 473
Prostatic Neoplasms 472 | 472
sonic hedgehog group medulloblastoma 459 | 459
posterior fossa group A ependymoma 456 | 456
Skin cancer 451 | 451
gastric cancer 445 | 445

Tissue

Digestive Tract 105 | 17,369
Female tissues 105 | 17,400
Endocrine System 104 | 18,159
Male tissues 104 | 17,142
Skin and soft tissues 104 | 17,230
Urinary Tract 103 | 16,678
Liver and Pancreas 100 | 16,750
Nervous System 99 | 16,725
Respiratory system 98 | 16,393
Blood and immune system 96 | 16,909
Cardiovascular System 95 | 15,192

Target Family

Non-IDG 75 | 12,091
Transcription Factor 16 | 1,400
Enzyme 8 | 4,145
Epigenetic 3 | 242
Kinase 3 | 634
Ion Channel 1 | 344

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transmembrane protein 216 TMEM216 Tbio Non-IDG -1.05847 10.9 0
Ellis-van Creveld syndrome protein EVC Tbio Non-IDG -2.18746 152.4 42
TRAF3-interacting protein 1 TRAF3IP1 Tbio Non-IDG -0.90740 11.2 169
Intraflagellar transport protein 80 homolog IFT80 Tbio Non-IDG -0.92606 9.26 52
WD repeat-containing protein 35 WDR35 Tbio Non-IDG -1.31497 20.6 39
Coiled-coil and C2 domain-containing protein 2A CC2D2A Tbio Non-IDG -1.23748 18.2 17
7-dehydrocholesterol reductase DHCR7 Tchem Enzyme -2.44252 276.5 109
Indian hedgehog protein IHH Tbio Non-IDG -2.61880 417.4 375
Polycystic kidney disease and receptor for egg jelly-related protein PKDREJ Tdark Ion Channel -3.42941 2602.1 26
Protein broad-minded TBC1D32 Tbio Non-IDG 0.01 1.03 53