Development Level

Tbio 222 | 10,625
Tchem 57 | 1,890
Tdark 30 | 7,003
Tclin 25 | 602

Collection

GPCR: IDG Consortium (Complete/Control) 1 | 24
GPCR: IDG Consortium (Targets) 1 | 128
Kinase: IDG Consortium (Targets) 1 | 125

IMPC Phenotype

preweaning lethality, complete... 17 | 633
decreased body weight 7 | 174
abnormal bone structure 6 | 131
decreased lean body mass 6 | 195
embryonic lethality prior to o... 6 | 148
embryonic lethality prior to t... 6 | 187
increased heart weight 6 | 37
abnormal behavior 5 | 226
increased circulating HDL chol... 5 | 63
abnormal bone mineralization 4 | 55
decreased body length 4 | 108
decreased bone mineral content 4 | 157
decreased bone mineral density 4 | 126
decreased circulating triglyce... 4 | 83
decreased grip strength 4 | 123
enlarged heart 4 | 111
increased bone mineral content 4 | 92
increased circulating alkaline... 4 | 119
abnormal embryo size 3 | 112
abnormal lung morphology 3 | 15
decreased circulating HDL chol... 3 | 77
decreased circulating LDL chol... 3 | 37
decreased circulating alanine ... 3 | 53
decreased circulating choleste... 3 | 85
decreased circulating serum al... 3 | 79
decreased lactate dehydrogenas... 3 | 14
decreased total body fat amoun... 3 | 186
hyperactivity 3 | 108
improved glucose tolerance 3 | 56
increased circulating choleste... 3 | 53
increased circulating serum al... 3 | 25
increased hematocrit 3 | 36
increased lean body mass 3 | 107
increased mean corpuscular hem... 3 | 93
preweaning lethality, incomple... 3 | 260
abnormal brain morphology 2 | 6
abnormal gait 2 | 51
abnormal heart morphology 2 | 51
abnormal lens morphology 2 | 73
abnormal retina morphology 2 | 100
decreased basophil cell number 2 | 11
decreased caudal vertebrae num... 2 | 49
decreased circulating aspartat... 2 | 27
decreased circulating creatini... 2 | 31
decreased circulating iron lev... 2 | 25
decreased circulating phosphat... 2 | 15
decreased eosinophil cell numb... 2 | 41
decreased lumbar vertebrae num... 2 | 62
increased circulating chloride... 2 | 43
increased sacral vertebrae num... 2 | 62
prenatal lethality prior to he... 2 | 64
short tibia 2 | 82
vertebral transformation 2 | 12
abnormal behavioral response t... 1 | 52
abnormal coping response 1 | 12
abnormal liver morphology 1 | 5
abnormal neural tube morpholog... 1 | 8
abnormal retinal pigmentation 1 | 61
abnormal rib morphology 1 | 28
abnormal skin morphology 1 | 23
abnormal tail movements 1 | 12
abnormal urinary bladder morph... 1 | 2
absent vibrissae 1 | 14
decreased IgG1 level 1 | 4
decreased Ly6C high monocyte n... 1 | 18
decreased blood urea nitrogen ... 1 | 31
decreased circulating bilirubi... 1 | 14
decreased circulating calcium ... 1 | 33
decreased effector memory CD8-... 1 | 24
decreased exploration in new e... 1 | 9
decreased heart rate 1 | 10
decreased hemoglobin content 1 | 53
decreased neutrophil cell numb... 1 | 37
decreased threshold for audito... 1 | 32
decreased total retina thickne... 1 | 20
dilated heart left ventricle 1 | 10
enlarged lymph nodes 1 | 27
hypoactivity 1 | 89
increased blood urea nitrogen ... 1 | 44
increased body weight 1 | 42
increased bone mineral density 1 | 52
increased circulating creatini... 1 | 29
increased circulating glycerol... 1 | 11
increased circulating iron lev... 1 | 25
increased circulating triglyce... 1 | 24
increased effector memory CD4-... 1 | 15
increased erythrocyte cell num... 1 | 26
increased fasted circulating g... 1 | 68
increased mean corpuscular vol... 1 | 91
increased rib number 1 | 41
increased total body fat amoun... 1 | 57
oligodactyly 1 | 14
premature death 1 | 5
small kidney 1 | 10
small thymus 1 | 11
thrombocytopenia 1 | 46
thrombocytosis 1 | 23
tremors 1 | 34
trunk curl 1 | 15
urinary bladder obstruction 1 | 2

Disease

Polycystic Ovary Syndrome 334 | 334
ovarian cancer 8,491 | 8,491
osteosarcoma 7,933 | 7,933
psoriasis 6,685 | 6,685
medulloblastoma, large-cell 6,234 | 6,234
glioblastoma 5,572 | 5,572
lung cancer 4,473 | 4,473
atypical teratoid / rhabdoid tumor 4,369 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 3,289 | 3,289
malignant mesothelioma 3,163 | 3,163
Breast cancer 3,098 | 3,098
pilocytic astrocytoma 3,086 | 3,086
primitive neuroectodermal tumor 3,031 | 3,031
intraductal papillary-mucinous carcinoma (IPMC) 2,988 | 2,988
intraductal papillary-mucinous adenoma (IPMA) 2,956 | 2,956
invasive ductal carcinoma 2,950 | 2,950
oligodendroglioma 2,849 | 2,849
lung carcinoma 2,844 | 2,844
non-small cell lung cancer 2,798 | 2,798
lung adenocarcinoma 2,714 | 2,714
pediatric high grade glioma 2,712 | 2,712
ependymoma 2,514 | 2,514
Cancer 2,346 | 2,346
pancreatic cancer 2,300 | 2,300
interstitial cystitis 2,299 | 2,299
subependymal giant cell astrocytoma 2,287 | 2,287
group 3 medulloblastoma 2,254 | 2,254
astrocytic glioma 2,241 | 2,241
adult high grade glioma 2,148 | 2,148
Carcinoma 2,147 | 2,147
ulcerative colitis 2,087 | 2,087
pituitary cancer 1,972 | 1,972
Pick disease 1,893 | 1,893
group 4 medulloblastoma 1,875 | 1,875
pancreatic ductal adenocarcinoma liver metastasis 1,795 | 1,795
ductal carcinoma in situ 1,745 | 1,745
cystic fibrosis 1,670 | 1,670
diabetes mellitus 1,663 | 1,663
breast carcinoma 1,614 | 1,614
tuberculosis 1,563 | 1,563
posterior fossa group B ependymoma 1,530 | 1,530
medulloblastoma 1,524 | 1,524
posterior fossa group A ependymoma 1,511 | 1,511
astrocytoma 1,493 | 1,493
sonic hedgehog group medulloblastoma 1,482 | 1,482
colon cancer 1,475 | 1,475
adrenocortical carcinoma 1,427 | 1,427
Multiple myeloma 1,327 | 1,327
primary pancreatic ductal adenocarcinoma 1,271 | 1,271
juvenile dermatomyositis 1,189 | 1,189
Rheumatoid Arthritis 1,170 | 1,170
acute quadriplegic myopathy 1,157 | 1,157
atypical teratoid/rhabdoid tumor 1,095 | 1,095
spina bifida 1,064 | 1,064
cutaneous lupus erythematosus 1,056 | 1,056
nasopharyngeal carcinoma 1,056 | 1,056
dermatomyositis 966 | 966
Atopic dermatitis 944 | 944
active Crohn's disease 918 | 918
non primary Sjogren syndrome sicca 840 | 840
gastric carcinoma 832 | 832
primary Sjogren syndrome 788 | 788
acute myeloid leukemia 785 | 785
Waldenstrons macroglobulinemia 764 | 764
esophageal adenocarcinoma 737 | 737
tuberculosis and treatment for 6 months 686 | 686
progressive supranuclear palsy 674 | 674
aldosterone-producing adenoma 664 | 664
Alzheimer's disease 644 | 644
Obesity 616 | 616
Duchenne muscular dystrophy 602 | 602
Intellectual disability 573 | 573
pancreatic carcinoma 567 | 567
fibroadenoma 557 | 557
hepatocellular carcinoma 550 | 550
Down syndrome 548 | 548
Endometriosis 535 | 535
chronic rhinosinusitis 512 | 512
Schizophrenia 503 | 503
autosomal dominant Emery-Dreifuss muscular dystrophy 499 | 499
Multiple Sclerosis 498 | 498
mucosa-associated lymphoid tissue lymphoma 480 | 480
active ulcerative colitis 477 | 477
Prostatic Neoplasms 471 | 471
IGA Glomerulonephritis 454 | 454
gastric cancer 436 | 436
Amyotrophic Lateral Sclerosis 432 | 432
non-small cell lung carcinoma 413 | 413
Mammary Neoplasms 410 | 410
inflammatory breast cancer 404 | 404
Kidney disease 397 | 397
Neurodegenerative disease 383 | 383
sarcoidosis 368 | 368
Parkinson's disease 364 | 364
Asthma 349 | 349
glioblastoma multiforme 347 | 347
Epilepsy 346 | 346
nephrosclerosis 329 | 329
tuberculosis and treatment for 3 months 327 | 327
Autistic Disorder 320 | 320

Tissue

Digestive Tract 330 | 18,472
Female tissues 329 | 18,646
Liver and Pancreas 329 | 18,135
Blood and immune system 328 | 17,994
Nervous System 328 | 18,560
Cardiovascular System 327 | 17,957
Endocrine System 327 | 18,511
Male tissues 326 | 17,968
Urinary Tract 325 | 18,443
Respiratory system 322 | 17,483
Skin and soft tissues 322 | 18,114

Target Family

Non-IDG 202 | 11,969
Enzyme 75 | 4,146
Transcription Factor 25 | 1,400
Kinase 12 | 634
GPCR 7 | 408
Transporter 6 | 473
Ion Channel 3 | 341
Epigenetic 2 | 242
Nuclear Receptor 2 | 48

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Thyroid adenoma-associated protein THADA Tbio Non-IDG -1.50722 29.2 46
ERBB receptor feedback inhibitor 1 ERRFI1 Tbio Non-IDG -1.84249 72.2 131
Insulin-like growth factor-binding protein 3 IGFBP3 Tchem Non-IDG -3.34747 2121.3 411
Large neutral amino acids transporter small subunit 1 SLC7A5 Tbio Transporter -1.84839 135.6 220
Intraflagellar transport protein 25 homolog HSPB11 Tbio Non-IDG -1.36468 21.9 56
Trinucleotide repeat-containing gene 6B protein TNRC6B Tbio Non-IDG -0.97375 6.84 59
Corticosteroid 11-beta-dehydrogenase isozyme 1 HSD11B1 Tclin Enzyme -2.88110 850.3 270
Progonadoliberin-1 GNRH1 Tbio Non-IDG -3.57398 3724.8 253
Probable ATP-dependent RNA helicase DDX6 DDX6 Tbio Enzyme -1.77534 57.8 244
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2 HSD3B2 Tclin Enzyme -2.04980 106.6 103