Development Level

Tbio 1,340 | 11,651
Tdark 332 | 6,593
Tchem 158 | 1,388
Tclin 64 | 612

Collection

RFA-RM-18-021 34 | 328
Ion Channel: IDG Consortium (T... 18 | 99
Kinase: IDG Consortium (Target... 17 | 125
Kinase: IDG Consortium (Comple... 9 | 37
GPCR: IDG Consortium (Complete... 1 | 25
GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

preweaning lethality, complete... 119 | 979
preweaning lethality, incomple... 89 | 499
abnormal behavior 51 | 298
decreased total body fat amoun... 45 | 207
embryonic lethality prior to t... 42 | 278
abnormal bone structure 32 | 187
increased total body fat amoun... 32 | 134
abnormal embryo size 31 | 220
embryonic lethality prior to o... 31 | 239
increased lean body mass 30 | 172
decreased bone mineral content 29 | 151
decreased body weight 26 | 161
enlarged heart 26 | 210
hyperactivity 26 | 148
decreased lean body mass 25 | 135
hypoactivity 25 | 132
increased circulating alkaline... 22 | 122
abnormal heart morphology 19 | 162
decreased prepulse inhibition 19 | 82
decreased vertical activity 19 | 208
decreased circulating glucose ... 18 | 126
decreased lymphocyte cell numb... 18 | 83
increased bone mineral content 18 | 108
decreased body length 17 | 101
decreased circulating serum al... 17 | 82
increased bone mineral density 17 | 72
decreased bone mineral density 16 | 126
decreased hemoglobin content 16 | 68
decreased leukocyte cell numbe... 16 | 73
increased mean corpuscular vol... 16 | 92
decreased grip strength 15 | 116
increased mean corpuscular hem... 15 | 96
increased startle reflex 15 | 112
decreased startle reflex 14 | 75
increased blood urea nitrogen ... 14 | 48
increased or absent threshold ... 14 | 101
decreased circulating insulin ... 13 | 76
decreased circulating triglyce... 13 | 79
embryonic growth retardation 13 | 106
male infertility 13 | 123
tremors 13 | 39
abnormal eye morphology 12 | 68
cataract 12 | 92
impaired glucose tolerance 12 | 75
increased monocyte cell number 12 | 63
decreased circulating choleste... 11 | 93
decreased circulating total pr... 11 | 49
increased heart weight 11 | 62
abnormal lens morphology 10 | 81
abnormal retina morphology 10 | 71
abnormal seminal vesicle morph... 10 | 114
decreased circulating alanine ... 10 | 47
decreased erythrocyte cell num... 10 | 62
decreased fasted circulating g... 10 | 65
decreased neutrophil cell numb... 10 | 42
increased fasted circulating g... 10 | 76
prenatal lethality prior to he... 10 | 87
abnormal coat-hair pigmentatio... 9 | 64
abnormal gait 9 | 69
abnormal sleep behavior 9 | 70
corneal opacity 9 | 32
decreased circulating HDL chol... 9 | 68
decreased circulating alkaline... 9 | 46
decreased hematocrit 9 | 46
decreased mean corpuscular vol... 9 | 79
increased circulating triglyce... 9 | 42
increased hemoglobin content 9 | 45
short tibia 9 | 97
abnormal cranium morphology 8 | 36
abnormal skin morphology 8 | 50
decreased circulating calcium ... 8 | 36
decreased mean corpuscular hem... 8 | 50
edema 8 | 59
increased circulating calcium ... 8 | 34
increased circulating chloride... 8 | 41
increased hematocrit 8 | 46
increased leukocyte cell numbe... 8 | 47
increased red blood cell distr... 8 | 34
limb grasping 8 | 41
abnormal testis morphology 7 | 43
absent startle reflex 7 | 24
decreased caudal vertebrae num... 7 | 53
decreased circulating amylase ... 7 | 28
improved glucose tolerance 7 | 79
increased body length 7 | 32
increased circulating choleste... 7 | 66
increased grip strength 7 | 41
increased mean corpuscular hem... 7 | 36
small superior vagus ganglion 7 | 74
small testis 7 | 58
thrombocytopenia 7 | 56
abnormal craniofacial morpholo... 6 | 33
abnormal epididymis morphology 6 | 42
abnormal joint morphology 6 | 23
abnormal kidney morphology 6 | 65
abnormal spleen morphology 6 | 55
decreased mean corpuscular hem... 6 | 31
increased circulating HDL chol... 6 | 80
increased prepulse inhibition 6 | 32
persistence of hyaloid vascula... 6 | 33

Disease

Pick disease 1,894 | 1,894
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Nervous System 1,881 | 16,725
Endocrine System 1,876 | 18,159
Digestive Tract 1,866 | 17,369
Female tissues 1,864 | 17,400
Skin and soft tissues 1,862 | 17,230
Male tissues 1,857 | 17,142
Liver and Pancreas 1,848 | 16,750
Urinary Tract 1,846 | 16,678
Blood and immune system 1,833 | 16,909
Respiratory system 1,831 | 16,393
Cardiovascular System 1,771 | 15,192

Target Family

Non-IDG 1,089 | 12,091
Enzyme 440 | 4,145
Transcription Factor 112 | 1,400
Kinase 92 | 634
Transporter 58 | 473
Ion Channel 48 | 344
Epigenetic 25 | 242
GPCR 19 | 408
Nuclear Receptor 6 | 48
TF/Epigenetic 5 | 38

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Elongation of very long chain fatty acids protein 2 ELOVL2 Tbio Non-IDG -1.99271 91.8 122
Paraspeckle component 1 PSPC1 Tbio Non-IDG -1.75415 48.3 19
Ras-related protein Rab-22A RAB22A Tbio Enzyme -1.40824 19.7 123
MAP kinase-interacting serine/threonine-protein kinase 1 MKNK1 Tchem Kinase -1.71576 46.7 408
Tyrosine-protein phosphatase non-receptor type 5 PTPN5 Tchem Enzyme -1.85420 70.8 225
Stonin-2 STON2 Tbio Non-IDG -1.43585 30.0 11
Paraneoplastic antigen Ma2 PNMA2 Tbio Non-IDG -2.92781 822.4 113
ATP-binding cassette sub-family A member 1 ABCA1 Tclin Transporter -3.15111 1451.8 388
Carbonyl reductase family member 4 CBR4 Tbio Enzyme -1.69083 48.5 128
Ras GTPase-activating protein 1 RASA1 Tbio Enzyme -2.61637 404.4 402