Development Level

Tbio 41 | 11,651
Tclin 21 | 612
Tchem 16 | 1,388
Tdark 9 | 6,593

IMPC Phenotype

decreased vertical activity 5 | 208
preweaning lethality, incomple... 4 | 499
decreased erythrocyte cell num... 3 | 62
embryonic lethality prior to t... 3 | 278
enlarged heart 3 | 210
increased mean corpuscular hem... 3 | 96
increased mean platelet volume 3 | 45
abnormal behavior 2 | 298
abnormal cranium morphology 2 | 36
abnormal heart morphology 2 | 162
abnormal seminal vesicle morph... 2 | 114
abnormal snout morphology 2 | 23
decreased bone mineral content 2 | 151
decreased hemoglobin content 2 | 68
improved glucose tolerance 2 | 79
increased circulating iron lev... 2 | 30
increased fasted circulating g... 2 | 76
male infertility 2 | 123
preweaning lethality, complete... 2 | 979
prolonged ST segment 2 | 36
tremors 2 | 39
abnormal bone structure 1 | 187
abnormal coat-hair pigmentatio... 1 | 64
abnormal cornea morphology 1 | 31
abnormal digit morphology 1 | 10
abnormal embryo size 1 | 220
abnormal gait 1 | 69
abnormal head size 1 | 6
abnormal maxilla morphology 1 | 17
abnormal pelvic girdle bone mo... 1 | 12
abnormal placement of pupils 1 | 6
abnormal retina morphology 1 | 71
abnormal skin morphology 1 | 50
abnormal testis morphology 1 | 43
convulsive seizures 1 | 13
corneal opacity 1 | 32
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating fructosa... 1 | 30
decreased circulating insulin ... 1 | 76
decreased circulating iron lev... 1 | 32
decreased fasted circulating g... 1 | 65
decreased hematocrit 1 | 46
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
decreased total body fat amoun... 1 | 207
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
impaired pupillary reflex 1 | 26
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating bilirubi... 1 | 16
increased circulating choleste... 1 | 66
increased circulating free fat... 1 | 20
increased circulating total pr... 1 | 28
increased large unstained cell... 1 | 5
increased lean body mass 1 | 172
increased red blood cell distr... 1 | 34
mammalian phenotype 1 | 17
mydriasis 1 | 6
narrow eye opening 1 | 12
pale yolk sac 1 | 25
prenatal lethality prior to he... 1 | 87
prolonged QT interval 1 | 38
small testis 1 | 58
syndactyly 1 | 23
thrombocytosis 1 | 27
vertebral transformation 1 | 12

Disease

Peripheral vascular disease 87 | 87
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Endocrine System 84 | 18,159
Liver and Pancreas 84 | 16,750
Digestive Tract 83 | 17,369
Urinary Tract 82 | 16,678
Blood and immune system 81 | 16,909
Nervous System 81 | 16,725
Skin and soft tissues 81 | 17,230
Female tissues 80 | 17,400
Male tissues 80 | 17,142
Respiratory system 80 | 16,393
Cardiovascular System 73 | 15,192

Target Family

Non-IDG 40 | 12,091
Enzyme 23 | 4,145
GPCR 8 | 408
Transcription Factor 6 | 1,400
Kinase 3 | 634
Ion Channel 2 | 344
Transporter 2 | 473
oGPCR 2 | 421
Nuclear Receptor 1 | 48

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Methylenetetrahydrofolate reductase MTHFR Tbio Enzyme -3.68447 5032.2 275
Endothelin-1 EDN1 Tbio Non-IDG -4.07520 12851.9 607
Interleukin-6 IL6 Tclin Non-IDG -4.50976 30968.8 2075
E-selectin SELE Tchem Non-IDG -3.44926 2672.1 919
HBS1-like protein HBS1L Tbio Non-IDG -2.55785 357.2 263
C-reactive protein CRP Tbio Non-IDG -4.57138 36497.6 1389
Voltage-dependent L-type calcium channel subunit alpha-1C CACNA1C Tclin Ion Channel -2.75188 537.5 330
Platelet factor 4 PF4 Tbio Non-IDG -3.30967 2121.0 327
Protein max MAX Tbio Transcription Factor -2.14268 110.6 398
Transferrin receptor protein 2 TFR2 Tbio Enzyme -2.11882 135.2 149