Development Level

Tbio 177 | 10,625
Tchem 82 | 1,890
Tclin 26 | 602
Tdark 18 | 7,003

Collection

Eligible Kinase Proteins 3 | 134

IMPC Term

abnormal behavior 10 | 226
preweaning lethality, incomple... 8 | 260
preweaning lethality, complete... 6 | 633
increased circulating alkaline... 5 | 119
increased circulating potassiu... 5 | 31
abnormal gait 4 | 51
abnormal retina morphology 4 | 100
decreased body weight 4 | 174
decreased grip strength 4 | 123
embryonic lethality prior to t... 4 | 187
enlarged heart 4 | 111
hyperactivity 4 | 108
abnormal epididymis morphology 3 | 31
abnormal lens morphology 3 | 73
abnormal retinal pigmentation 3 | 61
decreased bone mineral content 3 | 157
decreased bone mineral density 3 | 126
decreased circulating alanine ... 3 | 53
decreased heart weight 3 | 44
hypoactivity 3 | 89
increased circulating alanine ... 3 | 11
increased circulating aspartat... 3 | 17
increased circulating choleste... 3 | 53
increased mean corpuscular hem... 3 | 93
abnormal embryo size 2 | 112
abnormal heart morphology 2 | 51
cataract 2 | 26
decreased circulating chloride... 2 | 32
decreased mean corpuscular hem... 2 | 34
decreased spleen weight 2 | 13
enlarged epididymis 2 | 27
increased blood urea nitrogen ... 2 | 44
increased grip strength 2 | 83
increased mean corpuscular vol... 2 | 91
long tibia 2 | 13
prenatal lethality prior to he... 2 | 64
straub tail 2 | 26
thrombocytopenia 2 | 46
abnormal behavioral response t... 1 | 52
abnormal bone structure 1 | 131
abnormal coat/hair pigmentatio... 1 | 54
abnormal lung morphology 1 | 15
abnormal retinal inner nuclear... 1 | 5
abnormal skin coloration 1 | 18
abnormal skin morphology 1 | 23
abnormal sleep behavior 1 | 63
abnormal testis morphology 1 | 30
cardiovascular system phenotyp... 1 | 35
corneal opacity 1 | 25
decreased CD4-positive, CD25-p... 1 | 24
decreased NK cell number 1 | 16
decreased body length 1 | 108
decreased cardiac muscle contr... 1 | 5
decreased caudal vertebrae num... 1 | 49
decreased circulating creatini... 1 | 31
decreased circulating magnesiu... 1 | 11
decreased circulating triglyce... 1 | 83
decreased effector memory CD8-... 1 | 24
decreased eosinophil cell numb... 1 | 41
decreased fasted circulating g... 1 | 49
decreased heart rate 1 | 10
decreased hemoglobin content 1 | 53
decreased lean body mass 1 | 195
decreased monocyte cell number 1 | 28
decreased neutrophil cell numb... 1 | 37
decreased rib number 1 | 59
decreased total retina thickne... 1 | 20
embryonic lethality prior to o... 1 | 148
enlarged lymph nodes 1 | 27
enlarged spleen 1 | 26
hydrops fetalis 1 | 22
impaired glucose tolerance 1 | 52
increased body weight 1 | 42
increased circulating HDL chol... 1 | 63
increased circulating bilirubi... 1 | 16
increased circulating calcium ... 1 | 32
increased circulating chloride... 1 | 43
increased circulating creatini... 1 | 29
increased circulating fructosa... 1 | 11
increased circulating glucose ... 1 | 16
increased circulating iron lev... 1 | 25
increased circulating serum al... 1 | 25
increased circulating sodium l... 1 | 71
increased circulating total pr... 1 | 20
increased eosinophil cell numb... 1 | 9
increased exploration in new e... 1 | 56
increased heart weight 1 | 37
increased hematocrit 1 | 36
increased hemoglobin content 1 | 45
increased lean body mass 1 | 107
increased leukocyte cell numbe... 1 | 37
increased lymphocyte cell numb... 1 | 9
increased or absent threshold ... 1 | 128
increased total body fat amoun... 1 | 57
lethargy 1 | 5
limb grasping 1 | 35
small adrenal glands 1 | 15
small seminal vesicle 1 | 6
small testis 1 | 37
tremors 1 | 34

Disease

Peripheral Neuropathy 303 | 303
ovarian cancer 8,492 | 8,492
osteosarcoma 7,933 | 7,933
psoriasis 6,685 | 6,685
medulloblastoma, large-cell 6,234 | 6,234
glioblastoma 5,572 | 5,572
lung cancer 4,473 | 4,473
atypical teratoid / rhabdoid tumor 4,369 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 3,289 | 3,289
malignant mesothelioma 3,163 | 3,163
Breast cancer 3,099 | 3,099
pilocytic astrocytoma 3,086 | 3,086
primitive neuroectodermal tumor 3,031 | 3,031
intraductal papillary-mucinous carcinoma (IPMC) 2,988 | 2,988
intraductal papillary-mucinous adenoma (IPMA) 2,956 | 2,956
invasive ductal carcinoma 2,950 | 2,950
oligodendroglioma 2,849 | 2,849
lung carcinoma 2,844 | 2,844
non-small cell lung cancer 2,798 | 2,798
lung adenocarcinoma 2,714 | 2,714
pediatric high grade glioma 2,712 | 2,712
ependymoma 2,514 | 2,514
Cancer 2,346 | 2,346
pancreatic cancer 2,300 | 2,300
interstitial cystitis 2,299 | 2,299
subependymal giant cell astrocytoma 2,287 | 2,287
group 3 medulloblastoma 2,254 | 2,254
astrocytic glioma 2,241 | 2,241
adult high grade glioma 2,148 | 2,148
Carcinoma 2,147 | 2,147
ulcerative colitis 2,087 | 2,087
pituitary cancer 1,972 | 1,972
Pick disease 1,893 | 1,893
group 4 medulloblastoma 1,875 | 1,875
pancreatic ductal adenocarcinoma liver metastasis 1,795 | 1,795
ductal carcinoma in situ 1,745 | 1,745
cystic fibrosis 1,670 | 1,670
diabetes mellitus 1,663 | 1,663
breast carcinoma 1,614 | 1,614
tuberculosis 1,563 | 1,563
posterior fossa group B ependymoma 1,530 | 1,530
medulloblastoma 1,524 | 1,524
posterior fossa group A ependymoma 1,511 | 1,511
astrocytoma 1,493 | 1,493
sonic hedgehog group medulloblastoma 1,482 | 1,482
colon cancer 1,475 | 1,475
adrenocortical carcinoma 1,427 | 1,427
Multiple myeloma 1,328 | 1,328
primary pancreatic ductal adenocarcinoma 1,271 | 1,271
juvenile dermatomyositis 1,189 | 1,189
Rheumatoid Arthritis 1,171 | 1,171
acute quadriplegic myopathy 1,157 | 1,157
atypical teratoid/rhabdoid tumor 1,095 | 1,095
spina bifida 1,064 | 1,064
cutaneous lupus erythematosus 1,056 | 1,056
nasopharyngeal carcinoma 1,056 | 1,056
dermatomyositis 967 | 967
Atopic dermatitis 944 | 944
active Crohn's disease 918 | 918
non primary Sjogren syndrome sicca 840 | 840
gastric carcinoma 832 | 832
primary Sjogren syndrome 789 | 789
acute myeloid leukemia 785 | 785
Waldenstrons macroglobulinemia 765 | 765
esophageal adenocarcinoma 737 | 737
tuberculosis and treatment for 6 months 686 | 686
progressive supranuclear palsy 674 | 674
aldosterone-producing adenoma 664 | 664
Alzheimer's disease 644 | 644
Obesity 616 | 616
Duchenne muscular dystrophy 602 | 602
Intellectual disability 573 | 573
pancreatic carcinoma 567 | 567
fibroadenoma 557 | 557
hepatocellular carcinoma 550 | 550
Down syndrome 548 | 548
Endometriosis 535 | 535
chronic rhinosinusitis 512 | 512
Schizophrenia 503 | 503
autosomal dominant Emery-Dreifuss muscular dystrophy 499 | 499
Multiple Sclerosis 498 | 498
mucosa-associated lymphoid tissue lymphoma 480 | 480
active ulcerative colitis 477 | 477
Prostatic Neoplasms 471 | 471
IGA Glomerulonephritis 454 | 454
gastric cancer 436 | 436
Amyotrophic Lateral Sclerosis 432 | 432
non-small cell lung carcinoma 413 | 413
Mammary Neoplasms 410 | 410
inflammatory breast cancer 404 | 404
Kidney disease 397 | 397
Neurodegenerative disease 383 | 383
sarcoidosis 368 | 368
Parkinson's disease 364 | 364
Asthma 349 | 349
glioblastoma multiforme 347 | 347
Epilepsy 346 | 346
Polycystic Ovary Syndrome 335 | 335
nephrosclerosis 329 | 329
tuberculosis and treatment for 3 months 327 | 327
Autistic Disorder 320 | 320

Tissue

Female tissues 299 | 18,647
Endocrine System 295 | 18,512
Digestive Tract 294 | 18,473
Nervous System 294 | 18,561
Male tissues 293 | 17,969
Blood and immune system 291 | 17,995
Liver and Pancreas 291 | 18,136
Skin and soft tissues 289 | 18,115
Urinary Tract 288 | 18,444
Cardiovascular System 285 | 17,958
Respiratory system 284 | 17,484

Target Family

Non-IDG 158 | 11,969
Enzyme 76 | 4,146
Kinase 25 | 634
Transcription Factor 17 | 1,400
Transporter 16 | 473
Epigenetic 3 | 242
Nuclear Receptor 3 | 48
GPCR 2 | 408
Ion Channel 2 | 341
TF/Epigenetic 1 | 38

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Solute carrier organic anion transporter family member 3A1 SLCO3A1 Tbio Transporter -1.38328 23.0 28
Adenine DNA glycosylase MUTYH Tbio Enzyme -2.83418 699.9 239
Low affinity immunoglobulin gamma Fc region receptor II-c FCGR2C Tbio Non-IDG -2.59865 595.2 0
Unconventional myosin-Va MYO5A Tbio Non-IDG -1.72093 48.8 66
Putative peripheral benzodiazepine receptor-related protein TSPO Tbio Non-IDG -3.04986 2078.3 186
Cell division control protein 6 homolog CDC6 Tchem Non-IDG -2.49821 321.6 473
Talin-2 TLN2 Tbio Non-IDG -1.31287 18.3 45
Methylated-DNA--protein-cysteine methyltransferase MGMT Tchem Enzyme -3.10644 1345.2 435
Zinc finger transcription factor Trps1 TRPS1 Tbio Transcription Factor -1.94257 98.5 61
Sulfotransferase 4A1 SULT4A1 Tbio Enzyme -1.84964 70.4 113