Development Level

Tbio 254 | 11,651
Tchem 54 | 1,388
Tclin 54 | 612
Tdark 3 | 6,593

Collection

Ion Channel: IDG Consortium (T... 3 | 99
RFA-RM-18-021 3 | 328
GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

preweaning lethality, complete... 50 | 979
embryonic lethality prior to o... 17 | 239
embryonic lethality prior to t... 13 | 278
abnormal behavior 11 | 298
decreased body weight 9 | 161
preweaning lethality, incomple... 9 | 499
abnormal embryo size 7 | 220
decreased bone mineral density 7 | 126
decreased circulating choleste... 7 | 93
increased mean corpuscular hem... 7 | 96
decreased circulating HDL chol... 5 | 68
decreased total body fat amoun... 5 | 207
impaired glucose tolerance 5 | 75
abnormal neural tube closure 4 | 46
decreased body length 4 | 101
decreased circulating alanine ... 4 | 47
decreased vertical activity 4 | 208
enlarged lymph nodes 4 | 37
hypoactivity 4 | 132
increased circulating sodium l... 4 | 71
increased prepulse inhibition 4 | 32
prenatal lethality prior to he... 4 | 87
abnormal eye morphology 3 | 68
decreased circulating serum al... 3 | 82
decreased circulating total pr... 3 | 49
decreased circulating triglyce... 3 | 79
decreased fasted circulating g... 3 | 65
decreased grip strength 3 | 116
decreased hemoglobin content 3 | 68
decreased lean body mass 3 | 135
enlarged heart 3 | 210
hyperactivity 3 | 148
increased blood urea nitrogen ... 3 | 48
increased bone mineral density 3 | 72
increased circulating amylase ... 3 | 25
increased circulating calcium ... 3 | 34
increased circulating chloride... 3 | 41
increased circulating potassiu... 3 | 29
increased heart weight 3 | 62
increased lean body mass 3 | 172
small kidney 3 | 16
thrombocytopenia 3 | 56
abnormal bone structure 2 | 187
abnormal embryo turning 2 | 31
abnormal epididymis morphology 2 | 42
abnormal forebrain development 2 | 20
abnormal hindbrain development 2 | 16
abnormal joint morphology 2 | 23
abnormal lung morphology 2 | 26
abnormal midbrain development 2 | 20
abnormal pancreas morphology 2 | 13
abnormal pelvic girdle bone mo... 2 | 12
abnormal retina morphology 2 | 71
abnormal seminal vesicle morph... 2 | 114
abnormal vertebrae morphology 2 | 18
anophthalmia 2 | 33
decreased basophil cell number 2 | 16
decreased bone mineral content 2 | 151
decreased circulating LDL chol... 2 | 38
decreased circulating aspartat... 2 | 34
decreased circulating fructosa... 2 | 30
decreased circulating glucose ... 2 | 126
decreased circulating phosphat... 2 | 27
decreased erythrocyte cell num... 2 | 62
decreased heart left ventricle... 2 | 28
decreased leukocyte cell numbe... 2 | 73
decreased mean corpuscular hem... 2 | 50
decreased mean platelet volume 2 | 25
decreased startle reflex 2 | 75
embryonic growth retardation 2 | 106
enlarged spleen 2 | 41
hydrometra 2 | 53
increased circulating alkaline... 2 | 122
increased circulating bilirubi... 2 | 16
increased circulating phosphat... 2 | 26
increased fasted circulating g... 2 | 76
increased mean platelet volume 2 | 45
increased startle reflex 2 | 112
pallor 2 | 34
persistence of hyaloid vascula... 2 | 33
short tibia 2 | 97
small spleen 2 | 19
small testis 2 | 58
thin ventricular wall 2 | 24
abnormal craniofacial morpholo... 1 | 33
abnormal cranium morphology 1 | 36
abnormal heart looping 1 | 5
abnormal lens morphology 1 | 81
abnormal neural tube morpholog... 1 | 12
abnormal spleen morphology 1 | 55
abnormal tail movements 1 | 12
abnormal tooth morphology 1 | 24
decreased caudal vertebrae num... 1 | 53
decreased circulating chloride... 1 | 30
decreased red blood cell distr... 1 | 41
enlarged urinary bladder 1 | 8
increased anti-nuclear antigen... 1 | 19
increased circulating choleste... 1 | 66
increased mean corpuscular vol... 1 | 92
increased red blood cell distr... 1 | 34

Disease

Pediatric failure to thrive 365 | 365
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Endocrine System 360 | 18,159
Digestive Tract 359 | 17,369
Skin and soft tissues 355 | 17,230
Blood and immune system 354 | 16,909
Male tissues 352 | 17,142
Urinary Tract 352 | 16,678
Nervous System 351 | 16,725
Liver and Pancreas 350 | 16,750
Female tissues 349 | 17,400
Respiratory system 343 | 16,393
Cardiovascular System 326 | 15,192

Target Family

Enzyme 147 | 4,145
Non-IDG 127 | 12,091
Transcription Factor 20 | 1,400
Transporter 20 | 473
Kinase 19 | 634
Ion Channel 13 | 344
Epigenetic 11 | 242
GPCR 4 | 408
Nuclear Receptor 3 | 48
TF/Epigenetic 1 | 38

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
GTP-binding protein SAR1b SAR1B Tbio Enzyme -1.91051 79.7 184
Tyrosine-protein kinase ZAP-70 ZAP70 Tchem Kinase -2.91589 798.2 1515
Poly(A)-specific ribonuclease PARN PARN Tbio Enzyme -1.87605 76.4 263
Sialin SLC17A5 Tbio Transporter -2.93541 845.6 63
Tyrosine-protein kinase JAK3 JAK3 Tclin Kinase -2.64385 453.7 292
Laminin subunit gamma-2 LAMC2 Tbio Non-IDG -2.09168 112.5 175
Laminin subunit beta-3 LAMB3 Tbio Non-IDG -2.07156 116.4 170
T-cell surface protein tactile CD96 Tbio Non-IDG -2.05505 111.7 205
Mannosyl-oligosaccharide glucosidase MOGS Tbio Enzyme -2.28289 185.6 149
Transmembrane protein 70, mitochondrial TMEM70 Tbio Non-IDG -1.36229 24.6 93