Development Level

Tbio 50 | 11,651
Tchem 22 | 1,388
Tclin 13 | 612

Collection

Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

preweaning lethality, complete... 10 | 979
abnormal behavior 5 | 298
decreased vertical activity 3 | 208
abnormal bone structure 2 | 187
abnormal head morphology 2 | 10
embryonic lethality prior to t... 2 | 278
impaired glucose tolerance 2 | 75
improved glucose tolerance 2 | 79
increased body weight 2 | 25
increased total body fat amoun... 2 | 134
preweaning lethality, incomple... 2 | 499
abnormal bone mineralization 1 | 38
abnormal cranium morphology 1 | 36
abnormal epididymis morphology 1 | 42
abnormal eye morphology 1 | 68
abnormal gait 1 | 69
abnormal lens morphology 1 | 81
abnormal startle reflex 1 | 15
abnormal stomach morphology 1 | 10
abnormal vocalization 1 | 21
cataract 1 | 92
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating alkaline... 1 | 46
decreased circulating amylase ... 1 | 28
decreased circulating aspartat... 1 | 34
decreased circulating bilirubi... 1 | 19
decreased circulating insulin ... 1 | 76
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular hem... 1 | 31
decreased neutrophil cell numb... 1 | 42
decreased red blood cell distr... 1 | 41
decreased total body fat amoun... 1 | 207
edema 1 | 59
embryonic lethality prior to o... 1 | 239
enlarged heart 1 | 210
hyperactivity 1 | 148
hypoactivity 1 | 132
increased bone mineral density 1 | 72
increased circulating iron lev... 1 | 30
increased circulating serum al... 1 | 22
increased circulating sodium l... 1 | 71
increased eosinophil cell numb... 1 | 11
increased hematocrit 1 | 46
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
increased red blood cell distr... 1 | 34
increased startle reflex 1 | 112
increased vertical activity 1 | 24
long tibia 1 | 25
mammalian phenotype 1 | 17
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
short tibia 1 | 97

Disease

Pancreatic Neoplasm 85 | 85
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Endocrine System 81 | 18,159
Digestive Tract 80 | 17,369
Male tissues 79 | 17,142
Blood and immune system 78 | 16,909
Female tissues 78 | 17,400
Liver and Pancreas 78 | 16,750
Skin and soft tissues 78 | 17,230
Urinary Tract 77 | 16,678
Nervous System 76 | 16,725
Respiratory system 76 | 16,393
Cardiovascular System 73 | 15,192

Target Family

Non-IDG 43 | 12,091
Enzyme 18 | 4,145
Transcription Factor 11 | 1,400
GPCR 5 | 408
Kinase 4 | 634
Nuclear Receptor 2 | 48
Ion Channel 1 | 344
Transporter 1 | 473

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Thymidine phosphorylase TYMP Tclin Enzyme -2.83170 677.8 514
Protein patched homolog 1 PTCH1 Tbio Non-IDG -3.04637 1057.4 452
Equilibrative nucleoside transporter 1 SLC29A1 Tclin Transporter -2.61544 427.2 413
Transforming growth factor beta-1 TGFB1 Tchem Non-IDG -3.84680 5672.0 1222
Signal transducer and activator of transcription 3 STAT3 Tchem Transcription Factor -3.81500 6459.7 1749
Matrix metalloproteinase-9 MMP9 Tchem Enzyme -3.96102 8811.6 1442
Krueppel-like factor 5 KLF5 Tbio Transcription Factor -2.24489 208.0 218
Partner and localizer of BRCA2 PALB2 Tbio Non-IDG -2.16005 165.4 154
E3 ubiquitin-protein ligase ZNRF3 ZNRF3 Tbio Enzyme -1.17415 16.1 57
Tumor necrosis factor ligand superfamily member 10 TNFSF10 Tbio Non-IDG -2.87006 661.9 949