Development Level

Tbio 18 | 11,445
Tclin 15 | 613
Tchem 6 | 1,598

IMPC Phenotype

preweaning lethality, complete... 9 | 979
embryonic lethality prior to o... 3 | 239
embryonic lethality prior to t... 3 | 278
enlarged heart 3 | 210
abnormal behavior 2 | 298
abnormal heart morphology 2 | 162
hypoactivity 2 | 132
increased lean body mass 2 | 172
abnormal bone structure 1 | 187
abnormal embryo size 1 | 220
abnormal forebrain development 1 | 20
abnormal gait 1 | 69
abnormal hindbrain development 1 | 16
abnormal lens morphology 1 | 81
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal tail movements 1 | 12
aorta dilation 1 | 3
cataract 1 | 92
decreased circulating choleste... 1 | 93
decreased circulating insulin ... 1 | 76
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased lactate dehydrogenas... 1 | 16
decreased lymphocyte cell numb... 1 | 83
decreased total body fat amoun... 1 | 207
hydrometra 1 | 53
improved glucose tolerance 1 | 79
increased circulating calcium ... 1 | 34
increased circulating phosphat... 1 | 26
increased heart weight 1 | 62
increased mean corpuscular hem... 1 | 96
increased monocyte cell number 1 | 63
microphthalmia 1 | 26
preweaning lethality, incomple... 1 | 499
prolonged QT interval 1 | 38
shortened QT interval 1 | 4
small epididymis 1 | 3
small seminal vesicle 1 | 10
small testis 1 | 58
vertebral fusion 1 | 23

Disease

Pallor of optic disc 39 | 39
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Digestive Tract 38 | 17,369
Endocrine System 38 | 18,159
Liver and Pancreas 38 | 16,750
Male tissues 38 | 17,142
Skin and soft tissues 38 | 17,230
Blood and immune system 37 | 16,909
Female tissues 37 | 17,400
Nervous System 37 | 16,725
Respiratory system 37 | 16,393
Urinary Tract 37 | 16,678
Cardiovascular System 33 | 15,192

Target Family

Enzyme 21 | 4,145
Non-IDG 11 | 12,091
Kinase 3 | 634
Ion Channel 1 | 344
Nuclear Receptor 1 | 48
Transcription Factor 1 | 1,400
Transporter 1 | 473

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial NDUFS1 Tclin Enzyme -1.42734 26.2 214
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 NDUFB9 Tclin Enzyme -2.43529 263.5 165
NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial NDUFS4 Tclin Enzyme -2.97252 871.7 197
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha PDE6A Tclin Enzyme -1.29228 20.3 111
Tyrosine-protein kinase Mer MERTK Tchem Kinase -2.27276 199.1 609
Bardet-Biedl syndrome 2 protein BBS2 Tbio Non-IDG -2.84516 693.9 69
Aryl-hydrocarbon-interacting protein-like 1 AIPL1 Tbio Non-IDG -1.73867 59.0 229
Peroxisome biogenesis factor 1 PEX1 Tbio Enzyme -0.77059 5.43 107
COUP transcription factor 1 NR2F1 Tbio Nuclear Receptor -2.00427 106.7 184
Mitofusin-2 MFN2 Tbio Non-IDG -2.68784 484.6 447