Development Level

Tbio 60 | 10,625
Tchem 22 | 1,890
Tclin 10 | 602
Tdark 4 | 7,003

Collection

Eligible non-olfactory GPCR Proteins 1 | 145

IMPC Term

preweaning lethality, complete... 8 | 633
abnormal head morphology 2 | 10
decreased body weight 2 | 174
decreased total body fat amoun... 2 | 186
hyperactivity 2 | 108
abnormal behavior 1 | 226
abnormal bone mineralization 1 | 55
abnormal cranium morphology 1 | 32
abnormal ear morphology 1 | 5
abnormal femur morphology 1 | 14
abnormal gait 1 | 51
abnormal humerus morphology 1 | 11
abnormal joint morphology 1 | 14
abnormal lens morphology 1 | 73
abnormal pelvic girdle bone mo... 1 | 11
abnormal radius morphology 1 | 8
abnormal retinal pigmentation 1 | 61
abnormal startle reflex 1 | 14
abnormal tibia morphology 1 | 14
abnormal ulna morphology 1 | 8
decreased CD8-positive, alpha-... 1 | 26
decreased NK T cell number 1 | 28
decreased T cell number 1 | 31
decreased body length 1 | 108
decreased circulating LDL chol... 1 | 37
decreased circulating alanine ... 1 | 53
decreased circulating aspartat... 1 | 27
decreased circulating glucose ... 1 | 121
decreased circulating glycerol... 1 | 19
decreased circulating iron lev... 1 | 25
decreased eosinophil cell numb... 1 | 41
decreased erythrocyte cell num... 1 | 43
decreased lactate dehydrogenas... 1 | 14
decreased lean body mass 1 | 195
decreased lumbar vertebrae num... 1 | 62
decreased mean corpuscular hem... 1 | 19
decreased monocyte cell number 1 | 28
decreased rib number 1 | 59
hydrops fetalis 1 | 22
impaired righting response 1 | 19
increased CD4-positive, CD25-p... 1 | 18
increased T cell number 1 | 15
increased alpha-beta T cell nu... 1 | 9
increased bone mineral density 1 | 52
increased circulating alkaline... 1 | 119
increased circulating creatini... 1 | 29
increased circulating phosphat... 1 | 24
increased fasted circulating g... 1 | 68
increased lean body mass 1 | 107
increased mean corpuscular vol... 1 | 91
increased monocyte cell number 1 | 27
increased or absent threshold ... 1 | 128
increased sacral vertebrae num... 1 | 62
polydactyly 1 | 22
short tibia 1 | 82

Disease

Osteoarthritis 96 | 96
ovarian cancer 8,492 | 8,492
osteosarcoma 7,933 | 7,933
psoriasis 6,685 | 6,685
medulloblastoma, large-cell 6,234 | 6,234
glioblastoma 5,572 | 5,572
lung cancer 4,473 | 4,473
atypical teratoid / rhabdoid tumor 4,369 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 3,289 | 3,289
malignant mesothelioma 3,163 | 3,163
Breast cancer 3,099 | 3,099
pilocytic astrocytoma 3,086 | 3,086
primitive neuroectodermal tumor 3,031 | 3,031
intraductal papillary-mucinous carcinoma (IPMC) 2,988 | 2,988
intraductal papillary-mucinous adenoma (IPMA) 2,956 | 2,956
invasive ductal carcinoma 2,950 | 2,950
oligodendroglioma 2,849 | 2,849
lung carcinoma 2,844 | 2,844
non-small cell lung cancer 2,798 | 2,798
lung adenocarcinoma 2,714 | 2,714
pediatric high grade glioma 2,712 | 2,712
ependymoma 2,514 | 2,514
Cancer 2,346 | 2,346
pancreatic cancer 2,300 | 2,300
interstitial cystitis 2,299 | 2,299
subependymal giant cell astrocytoma 2,287 | 2,287
group 3 medulloblastoma 2,254 | 2,254
astrocytic glioma 2,241 | 2,241
adult high grade glioma 2,148 | 2,148
Carcinoma 2,147 | 2,147
ulcerative colitis 2,087 | 2,087
pituitary cancer 1,972 | 1,972
Pick disease 1,893 | 1,893
group 4 medulloblastoma 1,875 | 1,875
pancreatic ductal adenocarcinoma liver metastasis 1,795 | 1,795
ductal carcinoma in situ 1,745 | 1,745
cystic fibrosis 1,670 | 1,670
diabetes mellitus 1,663 | 1,663
breast carcinoma 1,614 | 1,614
tuberculosis 1,563 | 1,563
posterior fossa group B ependymoma 1,530 | 1,530
medulloblastoma 1,524 | 1,524
posterior fossa group A ependymoma 1,511 | 1,511
astrocytoma 1,493 | 1,493
sonic hedgehog group medulloblastoma 1,482 | 1,482
colon cancer 1,475 | 1,475
adrenocortical carcinoma 1,427 | 1,427
Multiple myeloma 1,328 | 1,328
primary pancreatic ductal adenocarcinoma 1,271 | 1,271
juvenile dermatomyositis 1,189 | 1,189
Rheumatoid Arthritis 1,171 | 1,171
acute quadriplegic myopathy 1,157 | 1,157
atypical teratoid/rhabdoid tumor 1,095 | 1,095
spina bifida 1,064 | 1,064
cutaneous lupus erythematosus 1,056 | 1,056
nasopharyngeal carcinoma 1,056 | 1,056
dermatomyositis 967 | 967
Atopic dermatitis 944 | 944
active Crohn's disease 918 | 918
non primary Sjogren syndrome sicca 840 | 840
gastric carcinoma 832 | 832
primary Sjogren syndrome 789 | 789
acute myeloid leukemia 785 | 785
Waldenstrons macroglobulinemia 765 | 765
esophageal adenocarcinoma 737 | 737
tuberculosis and treatment for 6 months 686 | 686
progressive supranuclear palsy 674 | 674
aldosterone-producing adenoma 664 | 664
Alzheimer's disease 644 | 644
Obesity 616 | 616
Duchenne muscular dystrophy 602 | 602
Intellectual disability 573 | 573
pancreatic carcinoma 567 | 567
fibroadenoma 557 | 557
hepatocellular carcinoma 550 | 550
Down syndrome 548 | 548
Endometriosis 535 | 535
chronic rhinosinusitis 512 | 512
Schizophrenia 503 | 503
autosomal dominant Emery-Dreifuss muscular dystrophy 499 | 499
Multiple Sclerosis 498 | 498
mucosa-associated lymphoid tissue lymphoma 480 | 480
active ulcerative colitis 477 | 477
Prostatic Neoplasms 471 | 471
IGA Glomerulonephritis 454 | 454
gastric cancer 436 | 436
Amyotrophic Lateral Sclerosis 432 | 432
non-small cell lung carcinoma 413 | 413
Mammary Neoplasms 410 | 410
inflammatory breast cancer 404 | 404
Kidney disease 397 | 397
Neurodegenerative disease 383 | 383
sarcoidosis 368 | 368
Parkinson's disease 364 | 364
Asthma 349 | 349
glioblastoma multiforme 347 | 347
Epilepsy 346 | 346
Polycystic Ovary Syndrome 335 | 335
nephrosclerosis 329 | 329
tuberculosis and treatment for 3 months 327 | 327
Autistic Disorder 320 | 320

Tissue

Endocrine System 96 | 18,512
Female tissues 96 | 18,647
Male tissues 96 | 17,969
Nervous System 96 | 18,561
Digestive Tract 95 | 18,473
Liver and Pancreas 95 | 18,136
Skin and soft tissues 95 | 18,115
Urinary Tract 95 | 18,444
Blood and immune system 94 | 17,995
Cardiovascular System 94 | 17,958
Respiratory system 93 | 17,484

Target Family

Non-IDG 53 | 11,969
Enzyme 26 | 4,146
GPCR 5 | 408
Transcription Factor 5 | 1,400
Kinase 3 | 634
Transporter 3 | 473
Epigenetic 1 | 242

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Prohibitin-2 PHB2 Tbio Non-IDG -2.94110 882.0 319
39S ribosomal protein L49, mitochondrial MRPL49 Tbio Non-IDG -2.70795 488.4 64
Beta-nerve growth factor NGF Tchem Non-IDG -4.00388 10626.8 510
Transcription factor Sp9 SP9 Tdark Transcription Factor -1.94388 82.1 11
Isovaleryl-CoA dehydrogenase, mitochondrial IVD Tbio Enzyme -3.09487 1224.3 81
Collagen alpha-1(II) chain COL2A1 Tbio Non-IDG -2.86562 689.3 377
Acrosomal protein SP-10 ACRV1 Tbio Non-IDG -2.27505 185.8 152
Xylosyltransferase 1 XYLT1 Tbio Enzyme -2.08783 122.1 75
Endoglin ENG Tbio Non-IDG -3.07363 1147.6 1239
Disintegrin and metalloproteinase domain-containing protein 12 ADAM12 Tchem Enzyme -2.26226 200.8 285