Development Level

Tbio 126 | 11,651
Tchem 34 | 1,388
Tclin 18 | 612
Tdark 6 | 6,593

Collection

GPCR: IDG Consortium (Targets) 2 | 126
RFA-RM-18-021 2 | 328

IMPC Phenotype

preweaning lethality, complete... 18 | 979
hyperactivity 5 | 148
decreased total body fat amoun... 4 | 207
embryonic lethality prior to o... 3 | 239
embryonic lethality prior to t... 3 | 278
abnormal behavior 2 | 298
abnormal femur morphology 2 | 14
abnormal gait 2 | 69
abnormal head morphology 2 | 10
decreased circulating glucose ... 2 | 126
decreased eosinophil cell numb... 2 | 24
decreased grip strength 2 | 116
decreased lean body mass 2 | 135
increased bone mineral density 2 | 72
increased circulating alkaline... 2 | 122
increased circulating phosphat... 2 | 26
increased or absent threshold ... 2 | 101
increased startle reflex 2 | 112
increased total body fat amoun... 2 | 134
preweaning lethality, incomple... 2 | 499
abnormal bone mineralization 1 | 38
abnormal cranium morphology 1 | 36
abnormal ear morphology 1 | 9
abnormal heart left ventricle ... 1 | 16
abnormal heart morphology 1 | 162
abnormal humerus morphology 1 | 11
abnormal joint morphology 1 | 23
abnormal pelvic girdle bone mo... 1 | 12
abnormal radius morphology 1 | 8
abnormal startle reflex 1 | 15
abnormal testis morphology 1 | 43
abnormal tibia morphology 1 | 14
abnormal tooth morphology 1 | 24
abnormal ulna morphology 1 | 8
abnormal vertebrae morphology 1 | 18
decreased body length 1 | 101
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating bilirubi... 1 | 19
decreased circulating creatine... 1 | 4
decreased circulating glycerol... 1 | 16
decreased circulating insulin ... 1 | 76
decreased circulating iron lev... 1 | 32
decreased erythrocyte cell num... 1 | 62
decreased hemoglobin content 1 | 68
decreased lactate dehydrogenas... 1 | 16
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular hem... 1 | 31
decreased mean corpuscular vol... 1 | 79
decreased vertical activity 1 | 208
dilated heart left ventricle 1 | 11
edema 1 | 59
enlarged lymph nodes 1 | 37
hydrometra 1 | 53
impaired glucose tolerance 1 | 75
impaired righting response 1 | 26
increased aggression 1 | 4
increased blood uric acid leve... 1 | 5
increased bone mineral content 1 | 108
increased circulating chloride... 1 | 41
increased circulating creatine... 1 | 5
increased circulating creatini... 1 | 38
increased circulating sodium l... 1 | 71
increased granulocyte number 1 | 1
increased heart weight 1 | 62
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 36
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
long tibia 1 | 25
mammalian phenotype 1 | 17
persistence of hyaloid vascula... 1 | 33
premature death 1 | 5
short tibia 1 | 97
small adrenal glands 1 | 16
small lymph nodes 1 | 1

Disease

Osteoarthritis 184 | 184
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Endocrine System 181 | 18,159
Female tissues 180 | 17,400
Digestive Tract 179 | 17,369
Skin and soft tissues 178 | 17,230
Male tissues 176 | 17,142
Liver and Pancreas 175 | 16,750
Blood and immune system 174 | 16,909
Nervous System 174 | 16,725
Urinary Tract 174 | 16,678
Respiratory system 170 | 16,393
Cardiovascular System 162 | 15,192

Target Family

Non-IDG 95 | 12,091
Enzyme 61 | 4,145
Transcription Factor 7 | 1,400
GPCR 6 | 408
Transporter 5 | 473
Kinase 4 | 634
Ion Channel 3 | 344
Epigenetic 2 | 242
Nuclear Receptor 1 | 48

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Myosin-13 MYH13 Tbio Non-IDG -1.26079 16.6 12
Alpha-ketoglutarate-dependent dioxygenase FTO FTO Tbio Enzyme -3.13021 1342.0 318
Tripartite motif-containing protein 47 TRIM47 Tbio Non-IDG -2.24070 172.9 79
Nuclear receptor coactivator 3 NCOA3 Tbio Epigenetic -2.64583 480.2 417
Chloride intracellular channel protein 4 CLIC4 Tbio Ion Channel -1.81713 70.5 221
Ezrin EZR Tbio Non-IDG -2.99865 981.3 1088
Progressive ankylosis protein homolog ANKH Tbio Non-IDG -2.03140 109.5 89
Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide DAPP1 Tbio Non-IDG -1.14626 21.0 307
C-reactive protein CRP Tbio Non-IDG -4.57138 36497.6 1389
Guanine nucleotide-binding protein-like 3 GNL3 Tbio Non-IDG -1.97262 100.0 310