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Development Level

Tbio 38 | 11,651
Tdark 10 | 6,593
Tchem 3 | 1,388
Tclin 3 | 612

Collection

Kinase: IDG Consortium (Target... 1 | 125
RFA-RM-18-021 1 | 328

IMPC Phenotype

increased circulating triglyce... 3 | 42
preweaning lethality, incomple... 3 | 499
abnormal behavior 2 | 298
abnormal bone structure 2 | 187
decreased leukocyte cell numbe... 2 | 73
increased circulating alkaline... 2 | 122
male infertility 2 | 123
abnormal embryo size 1 | 220
abnormal placenta size 1 | 20
abnormal tail movements 1 | 12
decreased body length 1 | 101
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased circulating bilirubi... 1 | 19
decreased circulating chloride... 1 | 30
decreased circulating glucose ... 1 | 126
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased neutrophil cell numb... 1 | 42
decreased startle reflex 1 | 75
decreased threshold for audito... 1 | 26
decreased vertical activity 1 | 208
enlarged heart 1 | 210
enlarged spleen 1 | 41
impaired glucose tolerance 1 | 75
increased blood urea nitrogen ... 1 | 48
increased cardiac muscle contr... 1 | 8
increased circulating aspartat... 1 | 15
increased mean corpuscular hem... 1 | 96
increased mean platelet volume 1 | 45
increased startle reflex 1 | 112
limb grasping 1 | 41
pallor 1 | 34
preweaning lethality, complete... 1 | 979
thrombocytopenia 1 | 56
vertebral fusion 1 | 23

Disease

Orofacial cleft 54 | 54
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Endocrine System 53 | 18,159
Nervous System 52 | 16,725
Male tissues 50 | 17,142
Digestive Tract 49 | 17,369
Female tissues 49 | 17,400
Skin and soft tissues 48 | 17,230
Urinary Tract 48 | 16,678
Liver and Pancreas 46 | 16,750
Blood and immune system 45 | 16,909
Respiratory system 44 | 16,393
Cardiovascular System 41 | 15,192

Target Family

Non-IDG 33 | 12,091
Transcription Factor 7 | 1,400
Enzyme 6 | 4,145
Kinase 4 | 634
GPCR 1 | 408
Ion Channel 1 | 344
Transporter 1 | 473
oGPCR 1 | 421

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Serine/threonine-protein kinase PAK 1 PAK1 Tchem Kinase -2.29299 237.8 1060
Thyroid adenoma-associated protein THADA Tbio Non-IDG -1.52487 33.2 60
FERM domain-containing protein 3 FRMD3 Tbio Non-IDG -1.25518 17.3 115
Protein sprouty homolog 2 SPRY2 Tbio Non-IDG -1.90829 87.6 217
Transthyretin TTR Tclin Non-IDG -3.79596 6198.3 750
DDB1- and CUL4-associated factor 4-like protein 2 DCAF4L2 Tdark Non-IDG 0.42 0.63 77
Acyl-coenzyme A thioesterase 12 ACOT12 Tbio Enzyme -1.10413 12.4 95
Kelch-like protein 26 KLHL26 Tdark Non-IDG 0.60 0.08 83
Junctional adhesion molecule C JAM3 Tbio Non-IDG -1.93757 97.1 251
Corticosteroid 11-beta-dehydrogenase isozyme 1 HSD11B1 Tclin Enzyme -2.90022 890.0 302