Development Level

Tbio 120 | 11,445
Tdark 13 | 6,588
Tchem 7 | 1,598
Tclin 2 | 613

Collection

Ion Channel: IDG Consortium (T... 2 | 99

IMPC Phenotype

increased or absent threshold ... 10 | 101
preweaning lethality, complete... 10 | 979
decreased prepulse inhibition 6 | 82
decreased startle reflex 6 | 75
preweaning lethality, incomple... 6 | 499
absent pinna reflex 5 | 23
absent startle reflex 4 | 24
decreased body weight 4 | 161
abnormal behavior 3 | 298
decreased circulating triglyce... 3 | 79
decreased total body fat amoun... 3 | 207
decreased vertical activity 3 | 208
embryonic lethality prior to t... 3 | 278
enlarged heart 3 | 210
hyperactivity 3 | 148
improved glucose tolerance 3 | 79
increased circulating sodium l... 3 | 71
increased lean body mass 3 | 172
abnormal craniofacial morpholo... 2 | 33
abnormal ear morphology 2 | 9
abnormal embryo size 2 | 220
decreased circulating amylase ... 2 | 28
decreased circulating free fat... 2 | 31
decreased eosinophil cell numb... 2 | 24
decreased mean corpuscular vol... 2 | 79
edema 2 | 59
embryonic growth retardation 2 | 106
impaired glucose tolerance 2 | 75
impaired righting response 2 | 26
increased leukocyte cell numbe... 2 | 47
increased mean corpuscular hem... 2 | 96
increased thermal nociceptive ... 2 | 9
increased total body fat amoun... 2 | 134
increased vertical activity 2 | 24
limb grasping 2 | 41
pallor 2 | 34
polycystic kidney 2 | 15
prenatal lethality prior to he... 2 | 87
stereotypic behavior 2 | 3
tremors 2 | 39
trunk curl 2 | 16
abnormal behavioral response t... 1 | 66
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal clavicle morphology 1 | 6
abnormal cranium morphology 1 | 36
abnormal digestive system phys... 1 | 1
abnormal embryo turning 1 | 31
abnormal facial morphology 1 | 17
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal liver morphology 1 | 17
abnormal locomotor activation 1 | 16
abnormal locomotor behavior 1 | 24
abnormal pericardium morpholog... 1 | 26
abnormal retina morphology 1 | 71
abnormal rib morphology 1 | 10
abnormal seminal vesicle morph... 1 | 114
abnormal sensory capabilities-... 1 | 8
abnormal spinal cord morpholog... 1 | 9
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
abnormal whole-body plethysmog... 1 | 4
cataract 1 | 92
cleft palate 1 | 8
cyanosis 1 | 7
decreased blood urea nitrogen ... 1 | 51
decreased bone mineral content 1 | 151
decreased caudal vertebrae num... 1 | 53
decreased circulating choleste... 1 | 93
decreased circulating fructosa... 1 | 30
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating potassiu... 1 | 20
decreased circulating serum al... 1 | 82
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
embryonic lethality prior to o... 1 | 239
enlarged lymph nodes 1 | 37
enlarged spleen 1 | 41
female infertility 1 | 60
hydrometra 1 | 53
increased blood urea nitrogen ... 1 | 48
increased bone mineral content 1 | 108
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased circulating triglyce... 1 | 42
increased fasted circulating g... 1 | 76
increased hemoglobin content 1 | 45
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
increased prepulse inhibition 1 | 32
increased startle reflex 1 | 112
persistence of hyaloid vascula... 1 | 33
prolonged PR interval 1 | 15
short tibia 1 | 97
small adrenal glands 1 | 16

Disease

Nonsyndromic deafness 142 | 142
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Endocrine System 136 | 18,159
Digestive Tract 129 | 17,369
Female tissues 129 | 17,400
Male tissues 129 | 17,142
Skin and soft tissues 129 | 17,230
Liver and Pancreas 128 | 16,750
Nervous System 125 | 16,725
Blood and immune system 124 | 16,909
Urinary Tract 123 | 16,678
Respiratory system 122 | 16,393
Cardiovascular System 103 | 15,192

Target Family

Non-IDG 93 | 12,091
Enzyme 21 | 4,145
Ion Channel 8 | 344
Transporter 7 | 473
Transcription Factor 6 | 1,400
Kinase 4 | 634
GPCR 2 | 408
Nuclear Receptor 1 | 48

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protocadherin-15 PCDH15 Tbio Non-IDG -1.83877 74.3 42
Unconventional myosin-XV MYO15A Tbio Non-IDG -1.64094 42.8 15
Testis anion transporter 1 SLC26A8 Tbio Transporter -0.96605 9.56 60
Harmonin USH1C Tbio Non-IDG -2.10689 124.7 188
G-protein coupled receptor 98 ADGRV1 Tbio GPCR -2.51228 316.6 64
Sodium-independent sulfate anion transporter SLC26A11 Tdark Transporter -0.88219 7.87 8
Beta-tectorin TECTB Tbio Non-IDG -1.23705 16.8 72
Calcium and integrin-binding protein 1 CIB1 Tbio Non-IDG -2.08897 121.1 264
Steroid hormone receptor ERR2 ESRRB Tchem Nuclear Receptor -1.95523 86.9 173
Glutaredoxin domain-containing cysteine-rich protein 2 GRXCR2 Tbio Non-IDG 0.00000 1.00 14