Development Level

Tbio 261 | 10,625
Tchem 88 | 1,890
Tclin 20 | 602
Tdark 14 | 7,003

Collection

Eligible Kinase Proteins 2 | 134
Eligible non-olfactory GPCR Proteins 1 | 143

IMPC Term

preweaning lethality, complete... 23 | 633
abnormal behavior 12 | 226
decreased total body fat amoun... 10 | 186
embryonic lethality prior to t... 10 | 187
preweaning lethality, incomple... 10 | 260
decreased bone mineral content 8 | 157
decreased circulating glucose ... 8 | 121
embryonic lethality prior to o... 8 | 148
decreased grip strength 7 | 123
decreased lean body mass 7 | 195
increased or absent threshold ... 7 | 128
abnormal bone structure 6 | 131
decreased circulating triglyce... 6 | 83
decreased rib number 6 | 59
hyperactivity 6 | 108
abnormal embryo size 5 | 112
decreased body length 5 | 108
decreased circulating HDL chol... 5 | 77
decreased circulating choleste... 5 | 85
decreased circulating insulin ... 5 | 75
decreased heart weight 5 | 44
decreased hemoglobin content 5 | 53
decreased mean corpuscular hem... 5 | 34
increased bone mineral content 5 | 92
increased circulating alkaline... 5 | 119
male infertility 5 | 62
abnormal gait 4 | 51
abnormal heart morphology 4 | 51
abnormal retina morphology 4 | 100
decreased body weight 4 | 174
decreased circulating iron lev... 4 | 25
decreased circulating serum al... 4 | 79
decreased mean corpuscular vol... 4 | 50
enlarged heart 4 | 111
hypoactivity 4 | 89
improved glucose tolerance 4 | 56
increased circulating choleste... 4 | 53
increased lean body mass 4 | 107
increased mean corpuscular hem... 4 | 93
limb grasping 4 | 35
short tibia 4 | 82
tremors 4 | 34
abnormal skin morphology 3 | 23
abnormal sleep behavior 3 | 63
decreased bone mineral density 3 | 126
decreased caudal vertebrae num... 3 | 49
decreased circulating glycerol... 3 | 19
decreased mean corpuscular hem... 3 | 19
decreased total retina thickne... 3 | 20
impaired glucose tolerance 3 | 52
increased bone mineral density 3 | 52
increased circulating sodium l... 3 | 71
increased grip strength 3 | 83
increased heart weight 3 | 37
increased mean corpuscular hem... 3 | 25
increased mean corpuscular vol... 3 | 91
persistence of hyaloid vascula... 3 | 22
straub tail 3 | 26
abnormal behavioral response t... 2 | 52
abnormal coat/hair pigmentatio... 2 | 54
abnormal coping response 2 | 12
abnormal epididymis morphology 2 | 31
abnormal heart left ventricle ... 2 | 20
abnormal kidney morphology 2 | 30
abnormal lens morphology 2 | 73
abnormal retinal inner nuclear... 2 | 5
abnormal rib morphology 2 | 28
abnormal tooth morphology 2 | 24
cardiovascular system phenotyp... 2 | 35
decreased T cell number 2 | 31
decreased circulating LDL chol... 2 | 37
decreased circulating bilirubi... 2 | 14
decreased circulating chloride... 2 | 32
decreased circulating potassiu... 2 | 17
decreased fasted circulating g... 2 | 49
decreased hematocrit 2 | 25
decreased lumbar vertebrae num... 2 | 62
decreased startle reflex 2 | 48
decreased thoracic vertebrae n... 2 | 7
decreased vertical activity 2 | 22
hydrops fetalis 2 | 22
increased blood urea nitrogen ... 2 | 44
increased body length 2 | 20
increased circulating HDL chol... 2 | 63
increased circulating aspartat... 2 | 17
increased circulating bilirubi... 2 | 16
increased circulating chloride... 2 | 43
increased circulating creatini... 2 | 29
increased circulating glucose ... 2 | 16
increased effector memory CD4-... 2 | 15
increased erythrocyte cell num... 2 | 26
increased fasted circulating g... 2 | 68
increased hemoglobin content 2 | 45
increased prepulse inhibition 2 | 21
increased sacral vertebrae num... 2 | 62
premature death 2 | 5
small testis 2 | 37
thrombocytopenia 2 | 46
thrombocytosis 2 | 23
vertebral fusion 2 | 23

Disease

Neurodegenerative disease 383 | 383
ovarian cancer 8,484 | 8,484
osteosarcoma 7,933 | 7,933
psoriasis 6,685 | 6,685
medulloblastoma, large-cell 6,234 | 6,234
glioblastoma 5,572 | 5,572
lung cancer 4,466 | 4,466
atypical teratoid / rhabdoid tumor 4,369 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 3,289 | 3,289
malignant mesothelioma 3,162 | 3,162
Breast cancer 3,094 | 3,094
pilocytic astrocytoma 3,086 | 3,086
primitive neuroectodermal tumor 3,031 | 3,031
intraductal papillary-mucinous carcinoma (IPMC) 2,988 | 2,988
intraductal papillary-mucinous adenoma (IPMA) 2,956 | 2,956
invasive ductal carcinoma 2,950 | 2,950
oligodendroglioma 2,849 | 2,849
lung carcinoma 2,844 | 2,844
non-small cell lung cancer 2,798 | 2,798
lung adenocarcinoma 2,713 | 2,713
pediatric high grade glioma 2,712 | 2,712
ependymoma 2,514 | 2,514
Cancer 2,346 | 2,346
pancreatic cancer 2,300 | 2,300
interstitial cystitis 2,299 | 2,299
subependymal giant cell astrocytoma 2,287 | 2,287
group 3 medulloblastoma 2,254 | 2,254
astrocytic glioma 2,241 | 2,241
adult high grade glioma 2,148 | 2,148
Carcinoma 2,147 | 2,147
ulcerative colitis 2,087 | 2,087
pituitary cancer 1,972 | 1,972
Pick disease 1,893 | 1,893
group 4 medulloblastoma 1,875 | 1,875
pancreatic ductal adenocarcinoma liver metastasis 1,795 | 1,795
ductal carcinoma in situ 1,745 | 1,745
cystic fibrosis 1,665 | 1,665
diabetes mellitus 1,663 | 1,663
breast carcinoma 1,614 | 1,614
tuberculosis 1,557 | 1,557
posterior fossa group B ependymoma 1,530 | 1,530
medulloblastoma 1,524 | 1,524
posterior fossa group A ependymoma 1,511 | 1,511
astrocytoma 1,493 | 1,493
sonic hedgehog group medulloblastoma 1,482 | 1,482
colon cancer 1,475 | 1,475
adrenocortical carcinoma 1,427 | 1,427
Multiple myeloma 1,327 | 1,327
primary pancreatic ductal adenocarcinoma 1,271 | 1,271
juvenile dermatomyositis 1,189 | 1,189
Rheumatoid Arthritis 1,160 | 1,160
acute quadriplegic myopathy 1,157 | 1,157
atypical teratoid/rhabdoid tumor 1,095 | 1,095
spina bifida 1,064 | 1,064
cutaneous lupus erythematosus 1,056 | 1,056
nasopharyngeal carcinoma 1,056 | 1,056
Atopic dermatitis 944 | 944
dermatomyositis 933 | 933
active Crohn's disease 918 | 918
non primary Sjogren syndrome sicca 840 | 840
gastric carcinoma 832 | 832
primary Sjogren syndrome 789 | 789
acute myeloid leukemia 780 | 780
Waldenstrons macroglobulinemia 765 | 765
esophageal adenocarcinoma 737 | 737
tuberculosis and treatment for 6 months 686 | 686
progressive supranuclear palsy 674 | 674
aldosterone-producing adenoma 664 | 664
Alzheimer's disease 644 | 644
Obesity 616 | 616
Duchenne muscular dystrophy 602 | 602
Intellectual disability 573 | 573
pancreatic carcinoma 567 | 567
fibroadenoma 557 | 557
Down syndrome 548 | 548
Endometriosis 535 | 535
hepatocellular carcinoma 532 | 532
chronic rhinosinusitis 512 | 512
Schizophrenia 501 | 501
autosomal dominant Emery-Dreifuss muscular dystrophy 499 | 499
Multiple Sclerosis 498 | 498
mucosa-associated lymphoid tissue lymphoma 480 | 480
active ulcerative colitis 477 | 477
Prostatic Neoplasms 471 | 471
IGA Glomerulonephritis 454 | 454
Amyotrophic Lateral Sclerosis 431 | 431
gastric cancer 430 | 430
non-small cell lung carcinoma 413 | 413
Mammary Neoplasms 410 | 410
inflammatory breast cancer 404 | 404
Kidney disease 396 | 396
Parkinson's disease 364 | 364
sarcoidosis 358 | 358
Asthma 349 | 349
glioblastoma multiforme 347 | 347
Epilepsy 346 | 346
Polycystic Ovary Syndrome 332 | 332
nephrosclerosis 329 | 329
tuberculosis and treatment for 3 months 327 | 327
Autistic Disorder 320 | 320

Tissue

Cardiovascular System 380 | 17,958
Digestive Tract 380 | 18,473
Female tissues 380 | 18,647
Nervous System 380 | 18,561
Blood and immune system 379 | 17,995
Endocrine System 379 | 18,512
Liver and Pancreas 379 | 18,136
Male tissues 379 | 17,969
Urinary Tract 378 | 18,444
Respiratory system 377 | 17,484
Skin and soft tissues 377 | 18,115

Target Family

Non-IDG 212 | 11,971
Enzyme 107 | 4,146
Kinase 19 | 634
Ion Channel 15 | 341
Transporter 13 | 473
Epigenetic 6 | 242
Transcription Factor 6 | 1,400
GPCR 3 | 406
Nuclear Receptor 1 | 48
TF/Epigenetic 1 | 38

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
C-reactive protein CRP Tbio Non-IDG -4.51399 33883.5 1160
Erythropoietin EPO Tbio Non-IDG -3.90053 8755.8 628
Apolipoprotein E APOE Tbio Non-IDG -4.17470 15380.4 788
Charged multivesicular body protein 2b CHMP2B Tbio Non-IDG -1.65708 53.0 166
Kinesin-like protein KIF1C KIF1C Tbio Non-IDG -1.21884 20.0 95
Proliferating cell nuclear antigen PCNA Tchem Non-IDG -1.10426 11.5 1277
Beta-1,4 N-acetylgalactosaminyltransferase 1 B4GALNT1 Tbio Enzyme -1.85387 67.6 146
Neurofilament heavy polypeptide NEFH Tbio Non-IDG -2.73883 563.3 681
Angiogenin ANG Tbio Enzyme -2.89794 796.0 203
Cytochrome c oxidase subunit 6A1, mitochondrial COX6A1 Tbio Enzyme -1.00384 11.8 165